A CMOS-based optical powering platform is proposed and demonstrated. Adopting an operation scheme with "charge and intermittent operation", we realized the optical powering platform that can drive blue LED and other electronics operating at 3V or higher. The minimum required area for solar cell system is as small as 1 mm2, and an implantable optical stimulation device for optogenetics with a volume of 1 mm3 was realized. It was also demonstrated that the proposed system is compatible with sequential operation, which is essential for intelligent biosensing and other applications including IoT and IoE (Internet of Everything) technology.