In design of steel-framed base isolated buildings, it is necessary to consider the stiffness and placement of the braces to prevent uplift of rubber bearings. This paper proposes a prediction method for uplift of rubber bearings of low to mid-rise braced, base isolated buildings subject to horizontal seismic ground motion. By using an equivalent spring model that considers the effect of vertical deformation of rubber bearings, a prediction equation for the axial compressive stress was derived as a function of inter-story deformation. The equation enables prediction of uplift of rubber bearings for different brace stiffnesses without the need for analysis.