"Tatsuya Onishi,Sachiko Matsuda,Yuki Nakamura,Junko Kuramoto,Akinori Tsuruma,Satoshi Sakamoto,Shunichi Suzuki,Daiichiro Fuchimoto,Akira Onishi,Shinichi Chikaki,Miki Kaneko,Akihiro Kuwahata,Masaki Sekino,Hiroshi Yasuno,Naohiro Hanyu,Tomoko Kurita,Hiroyuki Takei,Takashi Sakatani,Kanae Taruno,Seigo NakamuraTetsu Hayashida,Hiromitsu Jinno,Moriaki Kusakabe,Hiroshi Handa,Kaori Kameyama,Yuukou Kitagawa","Magnetically-promoted rapid immunofluorescence staining for frozen tissue sections.",,"J. Histochem. Cytochem.",,"vol. 67",,"p. 575-587",2019,Apr. "Kimura A.,Kitajima, M.,Nishida, K.,Serada, S.,Fujimoto, M.,Naka, T.,Fujii-Kuriyama, Y.,Satoshi Sakamoto,Takumi Ito,HIROSHI HANDA,Tanaka, T.,Yoshimura, A,Suzuki, H.","NQO1 inhibits TLR-dependent production of selective cytokines by promoting PDLIM2-mediated degradation of IkB-z",,"J. Exp. Med.",,"Vol. 215","No. 8","p. 2197-2209",2018,June "Tomoyuki Mori,Takumi Ito,Shujie Liu,Hideki Ando,Satoshi Sakamoto,Yuki Yamaguchi,Etsuko Tokunaga,Norio Shibata,Hiroshi Handa","Structural basis of thalidomide enantiomer binding to cereblon",,"Scientific Reports",," 8"," 1"," 1294",2018,Jan. "坂本 聡,Gupta Vipul,劉 舒捷,安藤秀樹,舘野峻平,金子裕生,湯上真人,石井亮平,濡木 理,山口雄輝,半田 宏","抗炎症薬サリチル酸が示す生体内作用メカニズムの解析","日本化学会年第97春季年会",,,,,,2017,Mar. "坂本 聡,山口 雄輝,半田宏","ターゲット因子の解析を基盤とする生物活性物質が示す作用機構の解明","新学術領域研究「転写サイクル」冬の若手ワークショップ2017",,,,,,2017,Jan. "坂本 聡,伊藤 拓水,森 智行,安藤 秀樹,山口 雄輝,箱嶋 敏雄,半田 宏","CRBNに対するサリドマイド光学異性体の結合基盤解析","日本ケミカルバイオロジー学会第11回年会",,,,,,2016,June "伊藤 拓水,朝妻 知子,山本 淳一,安藤 秀樹,佐藤 智美,山口 雄輝,半田 宏","リガンド依存的ユビキチンリガーゼCRBNの制御機構","日本ケミカルバイオロジー学会第11回年会",,,,,,2016,June "Yasuaki Kabe,Takanori Nakane,Ikko Koike,Tatsuya Yamamoto,Yuki Sugiura,Erisa Harada,Kenji Sugase,Tatsuro Shimamura,Mitsuyo Ohmura,Kazumi Muraoka,Ayumi Yamamoto,Takeshi Uchida,So Iwata,Yuki Yamaguchi,Elena Krayukhina,Masanori Noda,Hiroshi Handa,Koichiro Ishimori,Susumu Uchiyama,Takuya Kobayashi,Makoto Suematsu","Haem-dependent dimerization of PGRMC1/sigma-2 receptor facilitates cancer proliferation and chemoresistance",,"Nat. Commun.",,"Vol. 7",,"pp. 11030",2016,Mar. "Satoshi Sakamoto,Yuki Yamaguchi,Takumi Ito,Hiroshi Handa","Elucidation of the molecular mechanisms of action of bioactive natural products using high performance affinity beads","PACIFCHEM2015",,,,,,2015,Dec. "Satoshi Sakamoto,Takumi Ito,Yuki Yamaguchi,Hideki Ando,Hiroshi Handa","Biochemical analyses of CRBN, the target protein for immunomodulatory drugs (IMiDs)","PACIFCHEM2015",,,,,,2015,Dec. "坂本 聡,伊藤 拓水,安藤 秀樹,山口 雄輝,半田 宏","IMiDs標的タンパク質CRBNの生化学的解析","日本ケミカルバイオロジー学会第10回年会",,,,,,2015,June "坂本 聡,山口雄輝,半田 宏","アフィニティビーズを利用した生物活性物質標的タンパク質の単離・同定・評価","日本薬学会第135年会",,,,,,2015,Mar. "半田宏,山口雄輝","新しい遺伝子工学 新版",,,"朝倉書店",,,,2014,Sept. "P?rez-Perarnau, A.,Preciado, S.,Palmeri, C. M.,Moncunill-Massaguer, C.,Iglesias-Serret, D.,Gonz?lez-Giron?s, D. M.,Miguel, M.,Satoki Karasawa,Sakamoto, S,Cosialls, A. M.,Rubio-Pati?o, C.,Saura-Esteller, J.,Ram?n, R.,Caja, L.,Fabregat, I.,Pons, G.,HIROSHI HANDA,Albericio, F.,Gil, J.,Lavilla, R.","A trifluorinated thiazoline scaffold leading to pro-apoptotic agents targeting prohibitins",,"Angew. Chem. Int. Ed.",,"Vol. 53",,"p. 10150-10154",2014,Sept. "曹 青福,陳 業熹,半田 宏,山口 雄輝","新規転写伸長因子ヒトRtf1が関与する転写制御の分子機構","新学術領域研究「転写サイクル」班会議2014",,,,,,2014,Aug. "山口雄輝,山本淳一,半田宏","ヒトRNA ポリメラーゼII 転写産物のプロセシング経路の選択機構","新学術領域研究「転写サイクル」班会議2014",,,,,,2014,Aug. "Junichi Yamamoto,Yuri Hagiwara,Kunitoshi Chiba,Tomoyasu Isobe,Takashi Narita,Hiroshi Handa,Yuki Yamaguchi","DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes.",,"Nat. Commun.",,"Vol. 5",,"pp. 4263",2014,June "坂本 聡,Vipul Gupta,劉 舒捷,安藤 秀樹,舘野 峻平,金子 裕生,湯上 真人,石井 亮平,濡木 理,山口 雄輝,半田 宏","抗炎症薬サリチル酸の生体内作用機構の解析","日本ケミカルバイオロジー学会第9回年会",,,,,,2014,June "Misao Takemoto,Yumi Kawamura,Mikako Hirohama,Yuki Yamaguchi,Hiroshi Handa,Hisato Saitoh,Yoichi Nakao,Manabu Kawada,Khan Khalid,Hiroyuki Koshino,Ken-ichi Kimura,Akihiro Ito,Minoru Yoshida","Inhibition of protein SUMOylation by davidiin, an ellagitannin from Davidia involucrata",,"J. Antibiot.",,"Vol. 67","No. 4","pp. 335-338",2014,Apr. "坂本 聡,唐澤 慧記,東 基記,笠間 健嗣,宮澤 啓介,山口 雄輝,半田 宏","ビタミンK2が引き起こすがん細胞のアポトーシス誘導機構の解析","日本化学会第94春季年会",,,,,,2014,Mar. "曹 青福,陳 業熹,半田 宏,山口 雄輝","転写伸長因子ヒトPaf1複合体が関与する転写制御の分子機構","新学術領域研究「転写サイクル」冬の若手ワークショップ2014",,,,,,2014,Jan. "Satoshi Sakamoto,Kenshi Omagari,Yoshinori Kita,Yusuke Mochizuki,Yasuyuki Naito,Shintaro Kawata,Sachiko Matsuda,Osamu Itano,Hiromitsu Jinno,Hiroya Takeuchi,Yuki Yamaguchi,Yuko Kitagawa,Hiroshi Handa","Magnetically Promoted Rapid Immunoreactions Using Functionalized Fluorescent Magnetic Beads: A Proof of Principle",,"Clinical Chemistry","American Association for Clinical Chemistry","Vol. 60","No. 4","pp. 610-620",2014,Jan. "柴田 紘孝,半田 宏,山口 雄輝","転写伸長因子DSIFおよびNELFがES細胞の多分化能維持に果たす役割","新学術領域研究「転写サイクル」冬の若手ワークショップ2014",,,,,,2014,Jan. "舩造 正英,伊藤 拓水,安藤 秀樹,山口 雄輝,半田 宏","多発性骨髄腫におけるCRBN 結合因子の探索及び解析","第36回日本分子生物学会年会",,,,,,2013,Dec. "飯田 結,伊藤 拓水,安藤 秀樹,山口 雄輝,半田 宏","サリドマイドターゲット分子CRBN の生化学的解析","第36回日本分子生物学会年会",,,,,,2013,Dec. "坂本聡,半田宏","技術予測レポート2023 上巻 「健康寿命の延伸を目指す」日本の技術編",,,"日本能率協会総合研究所, ソレカラ社",,,,2013,Dec. "Hitomi Miyazaki,Ken Higashimoto,Yukari Yada,Takaho A. Endo,Jafar Sharif,Toshiharu Komori,Masashi Matsuda,Yoko Koseki,Manabu Nakayama,Hidenobu Soejima,Hiroshi Handa,Haruhiko Koseki,Susumu Hirose,Kenichi Nishioka","Ash1l Methylates Lys36 of Histone H3 Independently of Transcriptional Elongation to Counteract Polycomb Silencing",,"PLoS Genet",,"Vol. 9","No. 11","p. e1003897",2013,Nov. "Shuji Iida,Kensuke Imai,Sachiko Matsuda,Osamu Itano,Mamoru Hatakeyama,Satoshi Sakamoto,Daisuke Kokuryo,Koji Okabayashi,Takashi Endo,Yoshiyuki Ishii,Hirotoshi Hasegawa,Ichio Aoki,Hiroshi Handa,Yuko Kitagawa","In vivo identification of sentinel lymph nodes using MRI and size-controlled and monodispersed magnetite nanoparticles",,"Journal of Magnetic Resonance Imaging",,"Vol. 38","No. 6","pp. 1346?1355",2013,Nov. "Vipul Gupta,Shujie Liu,Hideki Ando,Ryohei Ishii,Shumpei Tateno,Yuki Kaneko,Masato Yugami,Satoshi Sakamoto,Yuki Yamaguchi,Osamu Nureki,Hiroshi Handa","Salicylic acid induces mitochondrial injury by inhibiting ferrochelatase heme biosynthesis activity",,"Mol. Pharmacol.",,"Vol. 84","No. 6","pp. 824-833",2013,Nov. "Kaoru Ohno,Jun-ichi Sawada,Shigeharu Takiya,Mai Kimoto,Akiko Matsumoto,Takuya Tsubota,Keiro Uchino,Chi-chung Hui,Hideki Sezutsu,Hiroshi Handa,Yoshiaki Suzuki","Silk Gland Factor-2, Involved in Fibroin Gene Transcription, Consists of LIM Homeodomain, LIM-interacting, and Single-stranded DNA-binding Proteins",,"J. biol. chem",,"Vol. 288",,"pp. 31581-31591",2013,Nov. "Teruya Enomoto,Masa-aki Kawano,Hajime Fukuda,Wataru Sawada,Takamasa Inoue,Kok Chee Haw,Yoshinori Kita,Satoshi Sakamoto,Yuki Yamaguchi,Takeshi Imai,Mamoru Hatakeyama,Shigeyoshi Saito,Adarsh Sandhu,Masanori Matsui,Ichio Aoki,Hiroshi Handa","Viral protein-coating of magnetic nanoparticles using simian virus 40 VP1",,"J. Biotechnol.",,"Vol. 167","No. 1","pp. 8-15",2013,Aug. "Teruya Enomoto,Masaaki Kawano,Hajime Fukuda,Wataru Sawada,Takamasa Inoue,Kok Chee Haw,Yoshinori Kita,Satoshi Sakamoto,Takeshi Imai,Mamoru Hatakeyama,Shigeyoshi Saito,Adarsh Sandhu,Masanori Matsui,Ichio Aoki,Hiroshi Handa","Viral protein-coating of magnetic nanoparticles using simian virus 40 VP1",,"Journal of Biotechnology",,"Vol. 167","No. 1","pp. 8-15",2013,Aug. "Jinsuk Kang,Zuolian Shen,Jae-Min Lim,Hiroshi Handa,Lance Wells,Dean Tantin","Regulation of Oct1/Pou2f1 transcription activity by O-GlcNAcylation",,"The FASEB Journal",,"Vol. 27","No. 7","pp. 2807-2817",2013,July "Kentaro Hotta,Akihiro Nashimoto,Eiji Yasumura,Masafumi Suzuki,Motoki Azuma,Yosuke Iizumi,Daisuke Shima,Ryusuke Nabeshima,Masaki Hiramoto,Akira Okada,Kumiko Sakata-Sogawa,Makio Tokunaga,Takumi Ito,Hideki Ando,Satoshi Sakamoto,Yasuaki Kabe,Shinichi Aizawa,Takeshi Imai,Yuki Yamaguchi,Hajime Watanabe,Hiroshi Handa","Vesnarinone suppresses TNFα mRNA expression by inhibiting valosin-containing protein",,"Mol. Pharmacol.",,"Vol. 83","No. 5","pp. 930-938",2013,May "半田宏,加部泰明,末松誠","見つける、量る、可視化する! 質量分析実験ガイド〜ライフサイエンス・医学研究で役立つ機器選択、サンプル調製、分析プロトコールのポイント",,"実験医学別冊 最強のステップUPシリーズ","羊土社",,,"pp. 58-68",2013,Apr. "Jeff Kershaw,Christoph Leuze,Ichio Aoki,Takayuki Obata,Iwao Kanno,Hiroshi Ito,Yuki Yamaguchi,Hiroshi Handa","Systematic changes to the apparent diffusion tensor of in vivo rat brain measured with an oscillating-gradient spin-echo sequence",,"Neuroimage",,"Vol. 70",,"pp. 10-20",2013,Apr. "Satoki Karasawa,Motoki Azuma,Takeshi Kasama,Satoshi Sakamoto,Yasuaki Kabe,Takeshi Imai,Yuki Yamaguchi,Keisuke Miyazawa,Hiroshi Handa","Vitamin K2 Covalently Binds to Bak and Induces Bak-Mediated Apoptosis",,"Molecular Pharmacology",,"Vol. 83","No. 3","pp. 613-620",2013,Mar. "Masaaki Kawano,Masanori Matsui,Hiroshi Handa","SV40 virus-like particles as an effective delivery system and its application to a vaccine carrier",,"Expert Review of Vaccines",,"Vol. 12","No. 2","pp. 199-210",2013,Feb. "Yuki Yamaguchi,Hirotaka Shibata,Hiroshi Handa","Transcription elongation factors DSIF and NELF: Promoter-proximal pausing and beyond",,"Biochimica et Biophysica Acta. Gene Regulatory Mechanisms",,"Vol. 1829","No. 1","pp. 98-104",2013,Jan. "Yuki Ito,Takumi Ito,Satoki Karasawa,Teruya Enomoto,Nashimoto, Akihiro,Hase, Yasuyoshi,Sakamoto, Satoshi,Mimori, Tsuneyo,Yoshihisa Matsumoto,Yuki Yamaguchi,HIROSHI HANDA","Identification of DNA-Dependent Protein Kinase Catalytic Subunit (DNA-PKcs) as a Novel Target of Bisphenol A",,"Plos One",,"Vol. 7","No. 12","p. e50481",2012,Dec. "Tadashi Wada,Masatoshi Hara,Takuya Taneda,Cao Qingfu,Ryouhei Takata,Kanako Moro,Kei Takeda,Takeo Kishimoto,Hiroshi Handa","Antisense morpholino targeting just upstream from a poly(A) tail junction of maternal mRNA removes the tail and inhibits translation",,"Nucleic Acids Res.",,"Vol. 40","No. 22","p. e173",2012,Dec. "Lopez-Girona,Mendy D,Ito T,Miller K,Gandhi AK,Kang J,Karasawa S,Carmel G,Jackson P,Abbasian M,Mahmoudi A,Cathers B,Rychak E,Gaidarova S,Chen R,Schafer PH,Handa H,Daniel TO,Evans JF,Chopra R.","Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide",,"Leukemia",,"Vol. 26","No. 11","pp. 2326-2335",2012,Nov. "Gil Diamant,Liat Amir-Zilberstein,Yuki Yamaguchi,Hiroshi Handa,Rivka Dikstein","DSIF Restricts NF-κB Signaling by Coordinating Elongation with mRNA Processing of Negative Feedback Genes",,"Cell Reports",,"Vol. 2","No. 4","pp. 722?731",2012,Oct. "西尾広介,坂本聡,宇賀均,倉森見典,半田宏","磁性ビーズのバイオ・環境技術への応用展開(普及版)",,"CMCテクニカルライブラリー―新材料・新素材シリーズ","シーエムシー出版",,,"pp. 144-153",2012,June "Emiko Okuda-Ashitaka,Toshiaki Minami,Shingo Tsubouchi,Hiroshi Kiyonari,Akihiro Iwamatsu,Tetsuo Noda,Hiroshi Handa,Seiji Ito","Identification of NIPSNAP1 as a nocistatin-interacting protein involving pain transmission",,"J Biol Chem",,"Vol. 287","No. 13","pp. 10403-10413",2012,Mar. "HIROSHI HANDA,Takumi Ito","Deciphering the mystery of thalidomide teratogenicity",,"Congenital Anomalies",,"Vol. 52","No. 1","pp. 1-7",2012,Mar. "Satoshi Sakamoto,Mamoru Hatakeyama,Takumi Ito,Hiroshi Handa","Tools and methodologies capable of isolating and identifying a target molecule for a bioactive compound",,"Bioorganic & Medicinal Chemistry",,"Vol. 20","No. 6","pp. 1990?2001",2012,Mar. "74. M. ABE,T. UEDA,T. MASAKI,Y. KITAMOTO,N. MATSUSHITA,H. HANDA","Detecting Ferrite Nanobeads for Sentinel Lymph Node Mapping with a Highly Sensitive Hall Differential Magnetic Field Sensor","Asia-PacificInterdisciplinaryResearchConference2011(AP-IRC2011)","Journal of physics : conference series",,"Vol. 352",," 012015",2012,Jan. "畠山士,半田宏","ナノ融合による先進バイオデバイス",,"バイオテクノロジーシリーズ","シーエムシー出版",,,"pp. 8-17",2011,Dec. "壷内信吾,池田森人,成松宏樹,半田宏","ソフトナノテクノロジーにおける材料開発(普及版)",,"CMCテクニカルライブラリー―新材料・新素材シリーズ","シーエムシー出版",,,,2011,Dec. "畠山士,加部泰明,半田宏","ナノ粒子分散系の基礎と応用",,"CMCテクニカルライブラリー―ファインケミカルシリーズ","シーエムシー出版",,,,2011,Nov. "Teruya Enomoto,Iwao Kukimoto,Masa-aki Kawano,Yuki Yamaguchi,Arnold J. Berk,Hiroshi Handa","In vitro reconstitution of SV40 particles that are composed of VP1/2/3 capsid proteins and nucleosomal DNA and direct efficient gene transfer",,"Virology",,"Vol. 420","No. 1","pp. 1-9",2011,Nov. "Yuichi Kitai,Hajime Fukuda,Teruya Enomoto,Yuki Asakawa,Takahiro Suzuki,Satoshi Inouye,Hiroshi Handa","Cell selective targeting of a simian virus 40 virus-like particle conjugated to epidermal growth factor",,"Journal of Biotechnology",,"Vol. 155","No. 2","pp. 251?256",2011,Sept. "Masaaki Kawano,Li Xing,Kit S. Lam,Hiroshi Handa,Tatsuo Miyamura,Susan Barnett,Indresh K. Srivastava,R. Holland Cheng","Development of Vaccines: From Discovery to Clinical Testing",,,"Wiley",,,"pp. 125-140",2011,Aug. "Ayako Yasuma,Toyoko Ochiai,Motoki Azuma,Hiroyuki Nishiyama,Ken Kikuchi,Masao Kondo,Hiroshi Handa","Exogenous coproporphyrin III production by Corynebacterium aurimucosum and Microbacterium oxydans in erythrasma lesions",,"J. Med. Microbiol.",,"Vol. 60"," Pt.7","pp. 1038-1042",2011,July "西尾広介,池田森人,成松宏樹,壺内信吾,郷右近展之,半田宏","医療分野における材料と機能膜(普及版)",,"CMCテクニカルライブラリー―新材料・新素材シリーズ","シーエムシー出版",,,"pp. 204-214",2011,June "Miho Aizawa,Yuichi Abe,Takumi Ito,Hiroshi Handa,Hiroyuki Nawa","mRNA distribution of the thalidomide binding protein cereblon in adult mouse brain",,"Neuroscience Research",,"Vol. 69","No. 4","pp. 343?347",2011,Apr. "Naoya Maekawa,Masaki Hiramoto,Satoshi Sakamoto,Motoki Azuma,Takumi Ito,Marie Ikeda,Michitaka Naitou,Hukum P. Acharya,Yuichi Kobayashi,Makoto Suematsu,Hiroshi Handa,Takeshi Imai","High-performance affinity purification for identification of 15-deoxy-Δ12,14-PGJ2 interacting factors using magnetic nanobeads",,"Biomedical Chromatography",,"Vol. 25","No. 4","pp. 466?471",2011,Apr. "Ayumi Kawano,Yohei Hayashi,Shuhei Noguchi,Hiroshi Handa,Masami Horikoshi,Yuki Yamaguchi","Global analysis for functional residues of histone variant Htz1 using the comprehensive point mutant library",,"Genes Cells",,"Vol. 16","No. 5","pp. 590-607",2011,Mar. "Takumi Ito,Hideki Ando,Hiroshi Handa","Teratogenic effects of thalidomide: molecular mechanisms",,"Cellular and Molecular Life Sciences",,"Vol. 68","No. 9","pp. 1569-1579",2011,Mar. "Mamoru Hatakeyama,Hiroshi Kishi,Yoshinori Kita,Kensuke Imai,Kosuke Nishio,Satoki Karasawa,Yuka Masaike,Satoshi Sakamoto,Adarsh Sandhu,Akihiro Tanimoto,Tatsuya Gomi,Eiichi Kohda,Masanori Abe,Hiroshi Handa","A two-step ligand exchange reaction generates highly water-dispersed magnetic nanoparticles for biomedical applications",,"Journal of Materials Chemistry",,"Vol. 21","No. 16","pp. 5959-5966",2011,Mar. "Takuya Taneda,Wenyan Zhu,Qingfu Cao,Hajime Watanabe,Yuki Yamaguchi,Hiroshi Handa,Tadashi Wada","Erythropoiesis is regulated by the transcription elongation factor Foggy/Spt5 through gata1 gene regulation",,"Genes to Cells",," 16"," 2"," 231?242",2011,Feb. "Adarsh Sandhu,Hiroshi Handa,Masanori Abe","Synthesis and applications of magnetic nanoparticles for biorecognition and point of care medical diagnostics",,"Nanotechnology",,"Vol. 21","No. 44","pp. 442001-442022",2010,Nov. "Kunitoshi Chiba,Junichi Yamamoto,Yuki Yamaguchi,Hiroshi Handa","Promoter-proximal pausing and its release: molecular mechanisms and physiological functions",,"Exp. Cell Res.",,"Vol. 316","No. 17","p. 2723-2730",2010,Oct. "Sol Kim,Junichi Yamamoto,Yexi Chen,Masatoshi Aida,Tadashi Wada,Hiroshi Handa,Yuki Yamaguchi","Evidence that cleavage factor Im is a heterotetrameric protein complex controlling alternative polyadenylation",,"Genes Cells",,"Vol. 15","No. 9","p. 1003-1013",2010,Sept. "半田宏,畠山士","コアシェル微粒子の設計・合成技術・応用の展開",,,"シーエムシー出版",,,"p. 204-214",2010,July "Masanori Abe,Hiroshi Handa","Biocompatible Nanomaterials: Synthesis, Characterization and Applications",,"Nanotechnology Science and Technology","Nova Science Pub Inc",,,"pp. 225-241",2010,July "Aiko Tominaga,Hideki Sugawara,Toshitaka Futagawa,Kazuhiko Inoue,Kazuki Sasaki,Naoto Minamino,Mamoru Hatakeyama,Hiroshi Handa,Atsuro Miyata","Characterization of the testis-specific promoter region in the human pituitary adenylate cyclase-activating polypeptide (PACAP) gene",,"Genes to Cells",,"Vol. 15","No. 6","pp. 595?606",2010,June "Masaki Hiramoto,Naoya Maekawa,Takeshi Kuge,Fumiaki Ayabe,Atsushi Watanabe,Yuka Masaike,Mamoru Hatakeyama,Hiroshi Handa,Takeshi Imai","High-performance affinity chromatography method for identification of L-arginine interacting factors using magnetic nanobeads",,"Biomedical Chromatography",,"Vol. 24","No. 6","pp. 606?612",2010,June "Sang Yoon Park,Pil Joo Ko,Hiroshi Handa,Adarsh Sandhu","Exploring magneto-optical properties of biofunctionalized magnetic chains for developing label-free immunoassays",,"Journal of Applied Physics",,"Vol. 107","No. 9","Page 09B324",2010,May "Yoshitaka Morimoto,Tsukasa Takamura,Sang Yoon Park,Satoshi Sakamoto,Shintaro Kawata,Hiroshi Handa,Adarsh Sandhu","Detection of 8 nm Diameter Superparamagnetic Beads by Magnetically-Induced Manipulation of Micrometer-Sized Magnetic Beads: A Novel Protocol for Magnetically-Labeled Biosensing",,"Japanese Journal of Applied Physics",,"Vol. 49",,"Page 04DL07",2010,Apr. "Kanako Kume,Yosuke Iizumi,Masashi Shimada,Yuki Ito,Tsutomu Kishi,Yuki Yamaguchi,Hiroshi Handa","Role of N-end rule ubiquitin ligases UBR1 and UBR2 in regulating the leucine-mTOR signaling pathway",,"Genes Cells",,"Vol. 15","No. 4","p. 339-349",2010,Apr. "壺内信吾,西尾広介,池田森人,成松宏樹,郷右近展之,半田宏","ナノ粒子・マイクロ粒子の調製と応用技術(普及版)",,"CMCテクニカルライブラリー―ファインケミカルシリーズ","シーエムシー出版",,,"pp. 219-228",2010,Apr. "半田宏,伊藤武彦,岩崎博史,岡田典弘,岸本健雄,工藤明,白髭克彦,田中幹子,徳永万喜洋,広瀬茂久,村上聡,菊池韶彦","ハートウェル遺伝学-遺伝子、ゲノム、そして生命システムへ-",,,"メディカルサイエンスインターナショナル",,,,2010,Mar. "Takumi Ito,Hideki Ando,Takayuki Suzuki,Toshihiko Ogura,Kentaro Hotta,Yoshimasa Imamura,Yuki Yamaguchi,Hiroshi Handa","Identification of a primary target of thalidomide teratogenicity",,"Science",,"Vol. 327","No. 5971","p. 1345-1350",2010,Mar. "Sang Yoon Park,Hiroshi Handa,Adarsh Sandhu","Magneto-Optical Biosensing Platform Based on Light Scattering from Self-Assembled Chains of Functionalized Rotating Magnetic Beads",,"NANO LETT.",,"Vol. 10","No. 2","pp. 446?451",2010,Feb. "Yuka Masaike,Takeshi Takagi,Masataka Hirota,Joe Yamada,Satoru Ishihara,Tetsu M. C. Yung,Takamasa Inoue,Chika Sawa,Hiroshi Sagara,Satoshi Sakamoto,Yasuyuki Takahashi,Yuki Yamaguchi,Hiroshi Handa,Yasuaki Kabe","Identification of Dynamin-2-Mediated Endocytosis as a New Target of Osteoporosis Drugs, Bisphosphonates",,"Molecular Pharmacology",,"Vol. 77","No. 2","pp. 262-269",2010,Feb. "Yexi Chen,Yuki Yamaguchi,Yuta Tsugeno,Junichi Yamamoto,Tomoko Yamada,Mitsuhiro Nakamura,Koji Hisatake,Hiroshi Handa","DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation",,"Genes Dev.",," 23"," 23"," 2765-2777",2009,Dec. "Hui Chen,Xavier Contreras,Yuki Yamaguchi,Hiroshi Handa,B. Matija Peterlin,Su Guo","Repression of RNA Polymerase II elongation in vivo is critically dependent on the C-terminus of Spt5",,"PLoS ONE",,"Vol. 4","No. 9","p. e6918",2009,Sept. "Hiroyuki Kamiya,Akihiro Suzuki,Yuki Yamaguchi,Hiroshi Handa,Hideyoshi Harashima","Incorporation of 8-hydroxyguanosine (8-oxo-7,8-dihydroguanosine) 5'-triphosphate by bacterial and human RNA polymerases",,"Free Radic. Biol. Med.",," 46"," 12"," 1703-1707",2009,June "Tetsu M. C. Yung,Takashi Narita,Toshiharu Komori,Yuki Yamaguchi,Hiroshi Handa","Cellular dynamics of the negative transcription elongation factor NELF",,"Exp. Cell Res.",," 315"," 10"," 1693-1705",2009,June "Chikanori Kuramori,Yasuyoshi Hase,Koichi Hoshikawa,Keiko Watanabe,Takeyuki Nishi,Takako Hishiki,Tomoyoshi Soga,Akihiro Nashimoto,Yasuaki Kabe,Yuki Yamaguchi,Hajime Watanabe,Kohsuke Kataoka,Makoto Suematsu,Hiroshi Handa","Mono-(2-ethylhexyl) phthalate targets glycogen debranching enzyme and affects glycogen metabolism in rat testis",,"Toxicol. Sci.",," 109"," 1"," 143-151",2009,May "Toshiharu Komori,Naoto Inukai,Tomoko Yamada,Yuki Yamaguchi,Hiroshi Handa","Role of human transcription elongation factor DSIF in the suppression of senescence and apoptosis",,"Genes Cells",," 14"," 3"," 343-354",2009,Mar. "Chikanori Kuramori,Motoki Azuma,Kanako Kume,Yuki Kaneko,Atsushi Inoue,Yuki Yamaguchi,Yasuaki Kabe,Takamitsu Hosoya,Masahiro Kizaki,Makoto Suematsu,Hiroshi Handa","Capsaicin binds to prohibitin 2 and displaces it from the mitochondria to the nucleus",,"Biochem. Biophys. Res. Commun.",," 379"," 2"," 519-525",2009,Feb. "半田宏,和田忠士,坂本聡","診断学、1.MEMSと診断 他",,"MEMS/NEMS工学全集","株式会社テクノシステム",,,"p. 212-217",2009, "Satoshi Sakamoto,Yasuaki Kabe,Mamoru Hatakeyama,Yuki Yamaguchi,Hiroshi Handa","Development and application of high-performance affinity beads: toward chemical biology and drug discovery",,"Chem. Rec.",," 9"," 1"," 66-85",2009, "HIROSHI HANDA","Preparation of spherical and uniform-sized ferrite nanoparticles with diameters between 50-150 nm for biomedical applications.",,"J.Magn. Magn. Mater",,"Vol. 321","No. 10","pp. 1417-1420",2009, "Yasuaki Kabe,Mamoru Hatakeyama,Satoshi Sakamoto,KOSUKE NISHIO,Hiroshi Handa","Novel Applications of Affinity Beads",,"PROTEIN TARGETING WITH SMALL MOLECULES, Chemical Biology Techniques and Applications","Jhon Wiley & Sons. Inc.",,,,2009, "山口雄輝,半田宏","転写制御とエピジェネティクス?ゲノムデコードに向けて",,,"南山堂",,,,2008,Dec. "NOBUHIRO MATSUSHITA,Kazunori Nakagawa,Takaaki Taniguchi,HIROSHI HANDA,Masaru TADA,masanori abe,MASAHIRO YOSHIMURA","Polymer Coated Magnetic Beads for Bio-screening Containing Ferrite Nanoparticles Synthesized by Hydrothermal Treatment","The 10th International Conference on Ferrite","The 10th Intl. Conf. on Ferrites (Chengdu, China)",,,,,2008,Oct. "Kozue Ando,Satoshi Hirao,Yasuaki Kabe,Yuji Ogura,Iwao Sato,Yuki Yamaguchi,Tadashi Wada,Hiroshi Handa","A new APE1/Ref-1-dependent pathway leading to reduction of NF-kappaB and AP-1, and activation of their DNA-binding activity",,"Nucleic Acids Res.",," 36"," 13"," 4327-4336",2008,Aug. "Motoki Azuma,Yasuaki Kabe,Chikanori Kuramori,Masao Kondo,Yuki Yamaguchi,Hiroshi Handa","Adenine nucleotide translocator transports haem precursors into mitochondria",,"PLoS One",," 3"," 8"," e3070",2008,Aug. "Ryou-u Takahashi,Shin-nosuke Kanesashi,Takamasa Inoue,Teruya Enomoto,Masa-aki Kawano,Hiroko Tsukamoto,Fumitaka Takeshita,Takeshi Imai,Takahiro Ochiya,Kohsuke Kataoka,Yuki Yamaguchi,Hiroshi Handa","Presentation of functional foreign peptides on the surface of SV40 virus-like particles",,"J. Biotechnol.",," 135"," 4"," 385-392",2008,July "Masafumi Suzuki,Shoichiro Furukawa,Chikanori Kuramori,Chika Sawa,Yasuaki Kabe,Mitsuhiro Nakamura,Jun-ichi Sawada,Yuki Yamaguchi,Satoshi Sakamoto,Satoshi Inouye,Hiroshi Handa","Development of a chemical screening system using aqueorin-fused protein",,"Biochem. Biophys. Res. Commun.",," 368"," 3"," 600-605",2008,Apr. "Matsushita Nobuhiro,Nakagawa Kazunori,Taniguchi Takaaki,Handa Hiroshi,Tada Masaru,Abe Masanori,Yoshimura Masahiro","Hundred-nanometer Sized Biomagnetic Beads with Large Magnetization Using Ferrite Nanoparticles Grown by Hydrothermal Process",,"Journal of Applied Physics",,"Volume 103","No. 7","p. 07A317",2008,Apr. "Toshiyuki Tanaka,Masaru Tada,Takashi Nakagawa,Masanori Abe,Adarsh Sandhu,Hiroshi Handa",""Flow Tubular Reactor Method" for Synthesis of Spherical","SMA International Conference 2008 & 5th International Symposium on Nanomanufacturing","SMA International Conference 2008 & 5th International Symposium on Nanomanufacturing",,,," 63",2008,Jan. "Kazunori NAKAGAWA,Takaaki TANIGUCHI,Nobuhiro MATSUSHITA,Hiroshi HANDA,Masanori ABE,Masahiro YOSHIMURA","Hundred-nanometer Sized Bio-Magnetic Beads with Large Magnetization Using Ferrite Nanoparticles Grown by Hydrothermal Process","MMM 2007","MMM 2007 Abstracts",,,,,2007,Nov. "阿部正紀,中川貴,多田大,SANDHUAdarsh,半田宏","医用磁性ナノビーズの作製と診断・治療への応用",,"臨床病理",,"Vol. 55",,"pp. 114",2007,Nov. "T. Kanemaru,T. Hara,M. Tada,T. Nakagawa,H. Handa,M. Abe","Ferrite hollow spheres, 200 nm in diameter, having continuous shell prepared by ferrite plating at low temperature for biomedical carrier application","52nd Magnetism and Magnetic Materials Conference","52nd Magnetism and Magnetic Materials Conference",,,,,2007,Nov. "金丸俊,原洸,多田大,中川貴,半田宏,阿部正紀","フェライトめっき反応を用いたフェライト中空ナノ粒子の低温(60℃)作製","第31回日本応用磁気学会学術講演会","第31回日本応用磁気学会学術講演会講演概要集",,,," 120",2007,Sept. "中川貴,田中俊行,島津隆一,志村拓真,金丸俊,黒田カルロス清一,多田大,半田宏,阿部正紀","バイオメディカル応用を目指したFeスピネルナノビーズの作製",,"日本セラミックス協会第20回秋季シンポジウム講演予稿集",,,," 45",2007,Sept. "Kazunori NAKAGAWA,Takaaki TANIGUCHI,Nobuhiro MATSUSHITA,Hiroshi HANDA,Masanori ABE,Masahiro YOSHIMURA","Biomagnetic Beads Using Fe3O4 Nanparticles Grown by Hydrothermal Process","IUMRS-ICMAT 2007","IUMRS-ICMAT 2007 Abstracts",,,,,2007,July "T. Tanaka*,R. Shimazu,M. Tada,T. Nakagawa,A. Sandhu,H. Handa,M. Abe","Size control (50-150 nm) of spherical monodisperse ferrite nanoparticles for biomedical applications","The 1st International Symposium on Advanced Magnetic Materials and Applications","ISAMMA2007",,,," 92",2007,May "Takashi Narita,Yung, T.M.C.,Junichi Yamamoto,Tsuboi, Y.,Tanabe, H.,Tanaka, K.,Yamaguchi, Y.,HIROSHI HANDA,,","NELF interacts with CBC and participates in 3'-end processing of replication-dependent histone mRNAs",,"Mol. Cell",,"Vol. 26","No. 3","pp. 349-365",2007,May "K. Okawa,T. Kanemaru,M. Tada,T. Nakagawa,Y. Hase,S Nomura,M. Ikeda,K. Nishio,H. Handa,M. Abe","Heating ability of iron oxide nanoparticles at 120-900 kHz for magnetic anticancer hyperthermia","The 1st International Symposium on Advanced Magnetic Materials and Applications","ISAMMA2007",,,," 9",2007,May "K. Nishio,M. Ikeda,N. Gokon,S. Tsubouchi,H. Narimatsu,Y. Mochizuki,S. Sakamoto,A. Sandhu,M. Abe,H. Handa","Preparation of size-controlled (30-100nm) magnetite nanoparticles for biomedical applications.",,"J. Magn. Magn. Mater.",,"Vol. 310",,"pp. 2408-2410",2007, "Adarsh Sandhu,Yoshimich Kumagai,Adam Lapicki,Satoshi Sakamoto,Masanori Abe,Hiroshi Handa","High efficiency Hall effect micro-biosensor platform for detection of magnetically labeled biomolecules",,"Biosensors & Bioelectronics",,"Vol. 2","No. 9-10","pp. 2115-2120",2007, "Hitoshi Uga,Chikanori Kuramori,Akiko Ohta,Yasunori Tsuboi,Hiroshi Tanaka,Mamoru Hatakeyama,Yuki Yamaguchi,Masahiro Kizaki,Takashi Takahashi,Hiroshi Handa","A new mechanism of methotrexate action revealed by target screening with affinity beads",,"Mol. Pharmacol.",,"Vol. 70","No. 5","pp. 1832-1839",2006,Aug. "Hisakage Funabashi,Yasuhiro Tanaka,Yoshimasa Imamura,Masayasu Mie,Takashi Manabe,Hiroshi Tanaka,Takashi Takahashi,Hiroshi Handa,Masuo Aizawa,Eiry Kobatake","Glucose oxidase assisted homogeneous electrochemical receptor binding assay for drug screening",,"Biosens Bioelectron",,"Vol. 21","No. 9","pp. 1675-1683",2006,June "Kumagai, Y.,Togawa, K.,Sakamoto, S.,Abe, M.,Handa, H.,Sandhu, A.","Hall biosensor with integrated current microstrips for control of magnetic beads.",,"IEEE Trans. Magn. Soc.",,"Vol. 42",,"pp. 3803",2006, "半田宏,和田忠士,山口雄輝","転写研究集中マスター",,,"羊土社",,,"pp. 12-26",2006, "半田宏,阿部正紀","「機能性磁性ビーズの構築とバイオテクノロジーへの応用(2)」",,"ライフサイエンスニュースレター 日本語版",,,"No. 4","pp. 31-33",2006, "中村栄一,濱口宏夫,半田宏","「化学の明日を考える」",,"化学",,"Vol. 1",,"pp. 12-17",2006, "Togawa, K.,Sanbonsugi, H.,Sandhu, A.,Narimatsu, H.,Nishio, K.,Handa, H.","Detection of magnetically labeled DNA using pseudomorphic AlGaAs/InGaAs/GaAs heterostructure micro-Hall biosensor.",,"J. Appl. Phys.",,"Vol. 99",,"pp. 08P103",2006, "Maeda, M.,Kuroda, S.,Shimura, T.,Tada, M.,Abe, M.,Yamamuro, S.,Sumiyama, K.,Handa, H.","Magnetic carriers of iron nanoparticles coated with a functional polymer for high thoughput bio-screening.",,"J. Appl. Phys.",,"Vol. 99",,"pp. 08H103",2006, "Okawa, K.,Sekine, M.,Maeda, M.,Tada, M.,Abe, M.,Matsushita, N.,Nishio, K.,Handa, H.","Heating ability of magnetite nanobeads with various sizes for magnetic hyperthermia at120kHz, a noninvasive frequency.",,"J. Appl. Phys.",,"Vol. 99",,"pp. 08H102",2006, "Yugami, M.,Kabe, Y.,Yamaguchi, Y.,Wada, T.,Handa, H.","hnRNP-U enhances the expression of specific genes by stabilizing mRNA.",,"FEBS Lett.",,"Vol. 581",,"pp. 1-7",2006, "Yamamoto, N.,Suzuki, M.,Kawano, M.,Inoue, T.,Takahashi, R.,Tsukamoto, H.,Enomoto, T.,Yamaguchi, Y.,Wada, T.,Handa, H.","Adeno-associated virus site-specific integration is regulated by TRP-185.",,"J.Virol.",,"Vol. 81",,"pp. 1990-2001",2006, "Uga, H.,Kuramori, C.,Ohta, A.,Tsuboi, Y.,Tanaka, H.,Hatakeyama, M.,Yamaguchi, Y.,Takahashi, T.,Kizaki, M.,Handa, H.","A new mechanism of methotrxate action revealed by target screening with affinity beads.",,"Mol. Pharmacol.",,"Vol. 70",,"pp. 1832-1839",2006, "Kabe, Y.,Ohmori, M.,Shinouchi, K.,Tsuboi, Y.,Hirao, S.,Azuma, M.,Watanabe, H.,Okura, I.,Handa, H.","Porphrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier.",,"J. Biol. Chem.",,"Vol. 281",,"pp. 31729-31735",2006, "Nishio, K.,Gokon, N.,Tsubouchi, S.,Ikeda, M.,Narimatsu, H.,Sakamoto, S.,Izumi, Y.,Abe, M.,Handa, H.","Direct Detection of Redox Reactions of Sulfur-containing Compounds on Ferrite Nanoparticle (FP) Surface.",,"Chem. Lett.",,"Vol. 35",,"pp. 974-975",2006, "Aida, M.,Chen, Y.,Nakajima, K.,Yamaguchi, Y.,Wada, T.,Handa, H.","Transcriptional pausing caused by NELF plays a dual role in regulating immediate-early expression of the junB gene.",,"Mol. Cell. Biol.",,"Vol. 26",,"pp. 6094-6104",2006, "Sakurai, N.,Miki, Y.,Suzuki, T,Watanabe, K.,Narita, T.,Ando, K.,Young, T.C.Y.,Aoki, D.,Sasano, H.,Handa, H.","Systemic Distribution and Tissue Localizations of Human 17beta-Hydroxysteroid Dehydrogenase Type 12.",,"J. Steroid Biochem. Mol. Biol.",,"Vol. 99",,"pp. 174-181",2006, "Kawano, M.,Inoue, T.,Tsukamoto, H.,Takaya, T.,Enomoto, T.,Takahashi, R. U.,Yokoyama, N.,Yamamoto, N.,Nakanishi, A.,Imai, T.,Wada, T.,Kataoka, K.,Handa, H.","The VP2/VP3 minor capsid ptotein of SV40 promotes the in vitro assembly of the major capsid protein VP1 into particles.",,"J. Biol. Chem.",,"Vol. 281",,"pp. 10164-10173",2006, "Ogura, Y.,Azuma, M.,Tsuboi, Y.,Kabe, Y.,Yamaguchi, Y.,Wada, T.,Watanabe, H.,Handa, H.","TFII-I down-regulates a subset of estrogen-responsive genes through its interaction with an initiator element and estrogen receptor alpha.",,"Genes Cells.",,"Vol. 11",,"pp. 373-381",2006, "野村祥太郎,望月勇輔,西尾広介,坂本聡,半田宏","ナノ磁性微粒子による遺伝子導入法",,,"遺伝子医学MOOK",,"No. 5",,2006, "半田宏,阿部正紀,野田紘憙","磁性ビーズのバイオ・環境技術への応用展開",,,"シーエムシー出版",,,,2006, "半田宏","新しい遺伝子工学",,,"昭晃堂",,,,2006, "半田宏,阿部正紀","機能性磁性ビーズの構築とバイオテクノロジーへの応用(2)",,,"ライフサイエンスニュースレター 日本語版",,"No. 4","pp. 31-33",2006, "半田 宏","東京工業大学21世紀COEプログラム 生命工学フロンティアシステム",,,"化学と工業","Vol. 6",,"pp. 4-8",2006, "加部泰明,坂本聡,半田宏","タンパク質を操るビーズ技術",,,"バイオニクス","Vol. 10",,"pp. 32-38",2006, "中村栄一,濱口宏夫,半田宏","化学の明日を考える",,,"化学","Vol. 1",,"pp. 12-17",2006, "Sophie Delehouzee,山口雄輝,半田宏","ヒトの分子生物学",,,"丸善株式会社",,,"pp. 618-635",2006, "半田宏","ナノ粒子分散系の化学と技術",,,"シーエムシー出版",,,"pp. 295-307",2006, "Kusunoki, N.,Ito, T.,Sakurai, N.,Handa, H.,Kawai S.","A celecoxib derivative potently inhibits proliferation of colon adenocarcinoma cells by induction of apoptosis.",,"Anticancer Res.",,"Vol. 26",,"pp. 3229-3236",2006, "Kubo, T.,Wada, T.,Yamaguchi, Y.,Shimizu, A.,Handa, H.","Knock-down of 25-kDa Subunit of Cleavage Factor Im in HeLa Cells Alters Alternative Polyadenylation within 3’UTRs.",,"Nucleic Acids Res.",,"Vol. 34",,"pp. 6264-6271",2006, "壷内信吾,池田森人,成松宏樹,半田宏","ソフトナノテクノロジー‐バイオマテリアル革命‐",,,"シ?エムシ?出版",,,,2005, "Shimizu, N.,Ouchida, R.,Yoshikawa, N.,Hisada, T.,Watanabe, H.,Okamoto, K.,Kusuhara, M.,Handa, H.,Morimoto, C,Tanaka, H.","HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b.",,"Proc. Natl. Acad. Sci. USA",,"Vol. 102",,"pp. 8555-8560",2005, "Kabe, Y.,Hirao, S.,Ando, K.,Handa, H.","Redox Regulation of NF-kappa B activation-the distinct redox regulation between the cytoplasm and the nucleus.",,"Antioxid. Redox. Signal.",,"Vol. 7",,"pp. 393-403",2005, "半田宏,阿部正紀","機能性磁性ビーズの構築とバイオテクノロジーへの応用(1)",,,"ライフサイエンスニュースレター 日本語版第3号",,,"pp. 29-31",2005, "川野雅章,金刺進之介,高橋陵宇,井上隆昌,半田宏","DDS研究の現状と将来展望",,,"PHARM TECH JAPAN","Vol. 12",,"pp. 168-171",2005, "半田宏 共訳","バイオテク用語辞典",,,"東京化学同人",,,,2005, "半田宏 共著","医療機器と再生医療―開発最前線と今後の動向―",,,"情報機構",,,,2005, "加部泰明,平尾聡,半田宏","ナノテクノロジ?の医学への応用-アフィニティナノ粒子を用いた医薬開発の応用展開-",,,"炎症と免疫","Vol. 2",,"pp. 3-10",2005, "郷右近展之,半田宏","機能性ナノ磁気ビ?ズの構築とバイオテクノロジ?への応用",,,"未来材料","Vol. 5",,"pp. 44-46",2005, "Delehouzee, S.,Yoshikawa, T.,Sawa, C.,Sawada,J-I.,Ito, T.,Omori, M.,Wada, T,Yamaguchi, Y.,Kabe, Y.,Handa, H.","GABP, HCF-1 and YY1 are involved in Rb gene expression during myogenesis.",,"Genes Cells",,"Vol. 10",,"pp. 717-731",2005, "Kusunoki, N.,Ito, T.,Sakurai, N.,Suguro, T.,Handa, H.,Kawai, S.","A novel celecoxib derivative potently induces apoptosis of human synovial fibroblasts.",,"J Pharmcol. Exp. Ther.",,"Vol. 314",,"pp. 796-803",2005, "Urano, A.,Endoh, M.,Wada, T.,Morikawa, Y.,Itoh, M.,Kataoka, Y.,Taki, T.,Akazawa, H.,Nakajima, H.,Komuro, I.,Yoshida, N.,Hayashi, Y.,Handa, H.,Kitamura, T.,Nosaka, T.","Infertility with defective spermiogenesis in mice lacking AF5q31, the target of  chromosomal translocation in human infant leukemia.",,"Mol. Cell. Biol.",,"Vol. 25",,"pp. 6834-6845",2005, "Azuma, N.,Tadokora, K.,Asaka, A.,Yamada, M.,Yamaguchi, Y.,Handa, H.,Matsushima, S.,Watanabe, T.,Kida, Y.,Ogura, T.,Shimamura, K.,Nakafuku, M.","Transdifferntiation of the retinal pigment epithelia to the neural retina by transfer of the Pax6 transcription factor.",,"Hum. Mol. Genet.",,"Vol. 14",,"pp. 1059-1068",2005, "Hasegawa, M.,Ohno, H.,Tanaka, H.,Hatakeyama, M.,Kawaguchi, H.,Takahashi, T.,Handa, H.","Affinity Identification of δ Opioid Receptors Using Latex Nanoparticles.",,"Bioorg. Med. Chem. Lett.",,"Vol. 16",,"pp. 158-161",2005, "Togawa. K.,Sanbonsugi. H.,Lapicki. A.,Abe. M.,Handa. H.,Sandhu, A.","High Sensitivity InSb Thin Film Micro-Hall Sensor Arrays for Simultaneous Multiple Detection of Magnetic Beads for Biomedical Applications",,"IEEE Trans Magn.",,"Vol. 41",,"pp. 3661-3663",2005, "Lapicki. A.,Sanbonsugi. H.,Yamamura. T.,Matsuhita. N.,Abe. M.,Narimatsu. H.,Handa. H.,Sandhu, A.","Functionalization of Micro-Hall Effect Sensors for Biomedical Applications Utilizing Superparamagnetic Beads",,"IEEE Trans Magn.",,"Vol. 41",,"pp. 4134-4136",2005, "Sandhu, A.,Handa. H.","Practical Hall Sensors for Biomedical Instrumentation",,"IEEE Trans Magn",,"Vol. 41",,"pp. 4123-4127",2005, "Wu,C-H.,Lee, C.,Fan, R.,Smith, J.M.,Yamaguchi, Y.,Handa, H.,Gilmour, D.S.","Molecular characterization of Drosophila NELF.",,"Nucleic Acids Res.",,"Vol. 33",,"pp. 1-11",2005, "Gang Wang,Michael A Balamotis,Jennitte L Stevens,Yuki Yamaguchi,Hiroshi Handa,Arnold Berk","Mediator Requirement for Both Recruitment and Post-Recruitment Steps in Transcription Initiation.",,"Mol.Cell",,"Vol. 5",,"pp. 683-694",2005, "Abe, M.,Matsushita, N.,Tada, M.,Gokon, N.,Nishio, K.,Handa, H.","Novel Medical Ferrite Nanobeads with Bioactive Molecules Immobilized Strongly onto the Surfaces","Mater. Res. Soc. 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Cell.",,"Vol. 5",,"pp. 683-694",2005, "Young, T.C.Y.,Rancourt, A.,Ho, E.L.Y.,Parent, M.,Vispe, S.,Suzuki-Matsuda, F.,Uehara, A.,Wada, T.,Handa, H.,Sato, M.","Poly(ADP-ribose)polymerase-1 is a negative regulator of HIV-1 expression through competitive binding to TAR RNA.",,"J. Biol. Chem.",,"Vol. 280",,"pp. 448-457",2005, "Ohtsu, Y.,Ohba, R.,Imamura, Y.,Kobayashi, M.,Hatori, H.,Zenkoh, T.,Hatakeyama, M.,Manabe, T.,Hino, M.,Yamaguchi, Y.,Kataoka, K.,Kawaguchi, H.,Watanabe, H.,Handa, H.","Selective ligand purification using high-performance affinity beads.",,"Anal. Biochem.",,"Vol. 338",,"pp. 245-252",2005, "Kabe, Y.,Yamada, J.,Uga, H.,Yamaguchi, Y.,Wada, T.,Handa, H.","NF-Y is essential for the recruitment of RNA polymerase II and synergistically acts the induced transcription on CCAAT box containing promoters.",,"Mol. Cell. 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Chem.",,"Vol. 277",,"pp. 44548-44556",2002, "半田宏 共著:小泉光惠,奥山喜久夫,目 義雄 編集","ナノ粒子の製造・評価・応用・機器の最新技術",,"Recent Advamces in Nano Power Technology-Preparation,Evaluation,Utilization and Equipments- (株)シーエムシー出版","Recent Advamces in Nano Power Technology-Preparation,Evaluation,Utilization and Equipments- (株)シーエムシー出版",,,,2002, "T.Oda,A.Ueda,N.Shimizu,H.Handa,T.Kasahara","Suppression of monocyte chemoattractant protein 1, but not IL-8, by alprazolam: Effect of alprazolam on c-Rel/p65 and c-Rel/p50 binding to the monocyte chemoattractant protein 1 promoter region.",,"J.Immunol",,"Vol. 169",,"pp. 3329-3335",2002, "Y.Yamaguchi,S.Delehouzee,H.Handa","HIV and HDV: evolution takes different paths to relieve blocks in transcriptional elongation.",,"Microbes and Infection",,"Vol. 4",,"pp. 1169-1175",2002, "H.Watanabe,A.Suzuki,T.Mizutani,S.Kohno,D.S.Lubahn,H.Handa,T.Iguchi.","Genome-wide analysis of changes in early gene expression induced by oestrogen.",,"Genes Cells",,"Vol. 7",,"pp. 497-507",2002, "Y.Yamaguchi,N.Inukai,T.Narita,T.Wada,H.Handa"," Evidence that NFLF represses transcription elongation through binding to a DSIF/RNA polymerase II complex and RNA.",,"Mol.Cell.Biol.",,"Vol. 22",,"pp. 2918-2927",2002, "M.Hiramoto,N.Shimizu,T.Nishi,D.Shima,S.Aizawa,H.Tanaka,M.Hatakeyama,H.Kawaguchi,H.Handa","High-performance affinity beads for identifying anti-NF-κB drug receptors.",,"Methods Enzymol.",,"Vol. 353",,"pp. 81-88",2002, " K.Nishimura,M.Hasegawa,Y.Ogura,T.Nishi,K.Kataoka,H.Handa,M.Abe.","4℃ preparation of ferrite nanoparticles having protein molecules immobilized on their surfaces.",,"J. 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Chem.",,"Vol. 277",,"pp. 22484-22490",2002, "半田 宏 編集,山口雄輝 共著","転写がわかる -基本転写から発生、再生、先端医療まで-",,"羊土社","羊土社",,,,2002, "半田 宏","サイエンスは個性&プライド",,"MEDCHEM NEWS 、社)日本薬学会","MEDCHEM NEWS 、社)日本薬学会","Vol. 12",,"pp. 6-9",2002, "半田 宏 共著,柳田 博明 監修","微粒子工学大系 第ニ巻 応用技術",,"フジ・テクノシステム","フジ・テクノシステム",,,,2002, "半田宏,古谷利夫,増保安彦,辻本豪三","「ゲノム創薬?創薬のパラダイム?」",,"中山書店","中山書店",,,,2001, "半田宏","「NAVIGATOR -Vascular Biologyナビゲーター‐」",,"メディカルレビュー社","メディカルレビュー社",,,,2001, "山口雄輝,半田宏","正反対の機能を使い分ける新たな転写調節因子、",,"化学と生物",,"Vol. 39",,"pp. 210-211",2001, "西剛志,長谷川慎,半田宏","生体レセプターを基盤とした創薬",,"ファルマシア",,"Vol. 37",,"pp. 491-495",2001, "T.Yoshimatsu,A.Saitoh,J.Ryu,D.Shima,H.Handa,M.Hiramoto,Y.Kawakami,S.Aizawa","Characterization of immortalized human chondrocytes originated from osteoarthritis cartilage",,"Int. J. Mol. 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