"荒川 翼,山口 雄輝,坂本 聡","神経変性疾患の原因であるタンパク質凝集体を選択的に分解誘導するPROTACの開発を目指した研究","第46回日本分子生物学会",,,,,,2023,Dec.
"Nutchaya Muksombat,Yuki Yamaguchi","A focused study of uncharacterized human genes containing putative nucleic acid-interacting motifs: toward a comprehensive understanding of the human genome","第46回日本分子生物学会",,,,,,2023,Dec.
"Noriyuki Azuma,Tadashi Yokoi,Taku Tanaka,Emiko Matsuzaka,Yuki Saida,Sachiko Nishina,Miho Terao,Shuji Takada,Maki Fukami,Kohji Okamura,Kayoko Maehara,Tokiwa Yamasaki,Jun Hirayama,Hiroshi Nishina,Hiroshi Handa,Yuki Yamaguchi","Integrator complex subunit 15 controls mRNA splicing and is critical for eye development",,"Hum. Mol. Genet.",,"vol. 32",,"pp. 2032-2045",2023,June
"奥田昌彦,諏訪哲史,鈴木秀文,山口雄輝,西村善文","ヒトRNAポリメラーゼと基本転写/修復因子TFIIHの新たな相互作用の構造生物学的研究","第45回日本分子生物学会",,,,,,2022,Dec.
"山本淳一,山口雄輝,半田宏","レナリドマイド耐性多発性骨髄腫細胞の生存に重要なポマリドマイド依存性CRL4CRBNのネオ基質ARID2の解析","第45回日本分子生物学会",,,,,,2022,Dec.
"原口大和,坂本聡,山口雄輝","二次元的スクリーニング解析を駆使した既存抗がん剤の新規作用機序の解明を目指した研究","第45回日本分子生物学会",,,,,,2022,Dec.
"高橋秀尚,鈴木秀文,阿部竜太,嶋田美穂,廣瀬智威,廣瀬博子,野口慶介,池陽子,安井七海,古郡華月,山口雄輝,豊田敦,鈴木穣,山本達郎,斉藤典子,Sato Shigeo,Tomomori-Sato Chieri,Conaway Joan,Canaway Ronald","Pol IIの一時停止および核体凝集体の制御におけるメディエーター複合体の役割","第45回日本分子生物学会",,,,,,2022,Dec.
"野口慶介,鈴木秀文,阿部竜太,池陽子,井野洋子,木村弥生,梁明秀,土井宏,田中章景,山口雄輝,高橋秀尚","新規ビオチン標識法を用いたマルチオミクス解析によるCajal body構成因子の網羅的解析とCajal body形成メカニズムの解明","第45回日本分子生物学会",,,,,,2022,Nov.
"Junichi Yamamoto,Tomoko Asatsuma-Okumura,Takumi Ito,Yuki Yamaguchi,Hiroshi Handa","History of IMiDs and Protein Degradation as a Pharmacological Modality",,"Protein Homeostasis in Drug Discovery: A Chemical Biology Perspective","John Wiley & Sons",,,,2022,Nov.
"鈴木秀文,阿部竜太,嶋田美穂,廣瀬智威,廣瀬博子,野口慶介,池陽子,安井七海,古郡華月,山口雄輝,豊田敦,鈴木穣,山本達郎,斉藤典子,Sato Shigeo,Tomomori-Sato Chieri,Conaway Ronald,Conaway Joan,高橋秀尚","メディエーター複合体による新規の転写スピード調節機構の解明","第45回日本分子生物学会",,,,,,2022,Nov.
"Junichi Yamamoto,Takumi Ito,Yuki Yamaguchi,Hiroshi Handa","Discovery of CRBN as a target of thalidomide: a breakthrough for progress in the development of protein degraders.",,"CHEM. SOC. REV.",,"  51",,"  6234-6250",2022,July
"Hidefumi Suzuki,Ryota Abe,Miho Shimada,Tomonori Hirose,Hiroko Hirose,Keisuke Noguchi,Yoko Ike,Nanami Yasui,Kazuki Furugori,Yuki Yamaguchi,Atsushi Toyoda,Yutaka Suzuki,Tatsuro Yamamoto,Noriko Saitoh,Shigeo Sato,Chieri Tomomori-Sato,Ronald Conaway,Joan Conaway,Hidehisa Takahashi","The 3′ Pol II pausing at replication-dependent histone genes is regulated by Mediator through Cajal bodies’ association with histone locus bodies",,"Nat. Commun.",,"  13","  1","  2905",2022,May
"Masahiko Okuda,Tetsufumi Suwa,Hidefumi Suzuki,Yuki Yamaguchi,Yoshifumi Nishimura","Three human RNA polymerases interact with TFIIH via a common RPB6 subunit",,"Nucleic Acids Res.",,"Vol. 50","No. 1","pp. 1-16",2022,Jan.
"諏訪哲史,奥田昌彦,鈴木秀文,西村善文,山口雄輝","共通サブユニットRPB6を介したヒトRNAポリメラーゼと基本転写因子TFIIHの相互作用","第44回日本分子生物学会",,,,,,2021,Dec.
"奥田昌彦,諏訪哲史,鈴木秀文,山口雄輝,西村善文","RNAポリメラーゼと基本転写/修復因子TFIIHの新たな相互作用","第39回染色体ワークショップ・第20回核ダイナミクス研究会",,,,,,2021,Dec.
"原口大和,坂本聡,山口雄輝","ナノ磁性ビーズ精製とCRISPRライブラリースクリーニングによる薬剤標的分子の網羅的同定を目指した研究","第44回日本分子生物学会",,,,,,2021,Dec.
"古屋智基,山口雄輝","In situ ビオチン化によるコヒーシン近傍因子の探索","第44回日本分子生物学会",,,,,,2021,Dec.
"山本淳一,山口雄輝,半田宏","ポマリドミド依存的なCRBNのネオ基質ARID2の解析","第44回日本分子生物学会",,,,,,2021,Dec.
"野口慶介,鈴木秀文,阿部竜太,池陽子,井野洋子,木村弥生,梁明秀,土井宏,田中章景,山口雄輝,高橋秀尚","新規ビオチン標識法を用いたマルチオミックス解析によるCajal body形成メカニズムの解明","第44回日本分子生物学会",,,,,,2021,Dec.
"鈴木秀文,阿部竜太,嶋田美穂,廣瀬智威,廣瀬博子,野口慶介,古郡華月,池陽子,安井七海,豊田敦,鈴木穣,山本達郎,斉藤典子,Ronald Conaway,Joan Conaway,山口雄輝,高橋秀尚","メディエーター複合体による新規の3' Pol IIポージング制御機構の解明","第44回日本分子生物学会",,,,,,2021,Dec.
"山本淳一,山口雄輝,半田宏","ホ?マリト?ミト?依存的な CRBN のネオ基質 ARID2 の解析","第44回日本分子生物学会年会",,,,,,2021,Dec.
"山口雄輝","RNAポリメラーゼとTFIIHの相互作用部位の細胞機能解析","BINDS-NMR報告会",,,,,,2021,Nov.
"Nobuyuki Shimizu,Tomoko Asatsuma-Okumura,Junichi Yamamoto,Yuki Yamaguchi,Hiroshi Handa,Takumi Ito","PLZF and its fusion proteins are pomalidomide-dependent CRBN neosubstrates",,"Commun. Biol.",,"  4","  1","  1277",2021,Nov.
"Takumi Ito,Yuki Yamaguchi,Hiroshi Handa","Exploiting ubiquitin ligase cereblon as a target for small-molecule compounds in medicine and chemical biology",,"Cell Chem. Biol.",,"  28","  7","  987-999",2021,July
"Junichi Yamamoto,Tetsufumi Suwa,Yuki Murase,Shunpei Tateno,Hirotaka Mizutome,Tomoko Asatsuma-Okumura,Nobuyuki Shimizu,Tsutomu Kishi,Shuji Momose,Masahiro Kizaki,Takumi Ito,Yuki Yamaguchi,Hiroshi Handa","ARID2 is a pomalidomide-dependent CRL4CRBN substrate in multiple myeloma cells",,"Nature Chemical Biology",,,,,2020,Sept.
"山口 雄輝","サリドマイド胎芽症診療ガイド 2020",,"サリドマイド胎芽症診療ガイド 2020","国立国際医療研究センター",,,,2020,May
"Shunpei Tateno,Midori Iida,Satoshi Fujii,Miki Katayama,Haruka Tokuyama,Junichi Yamamoto,Takumi Ito,Satoshi Sakamoto,Hiroshi Handa,Yuki Yamaguchi","Genome-wide screening reveals a role for subcellular localization of CRBN in the anti-myeloma activity of pomalidomide?",,"Scientific Reports",,"Volume 10","Number 4012",,2020,Mar.
"Takahashi H,Ranjan A,Chen S,Suzuki H,Shibata M,Hirose T,Hirose H,Sasaki K,Abe R,Chen K,He Y,Zhang Y,Takigawa I,Tsukiyama T,Watanabe M,Fujii S,Iida M,Yamamoto J,Yamaguchi Y,Suzuki Y,Matsumoto M,Nakayama KI,Washburn MP,Saraf A,Florens L,Sato S,Tomomori-Sato C,Conaway RC,Conaway JW,Hatakeyama S","The role of Mediator and Little Elongation Complex in transcription termination",,"Nat Commun.",,"Vol. 11","No. 1","p. 1063",2020,Feb.
"高森 朝浩,Fajar Muhamad,山口 雄輝","タンパク質コード遺伝子の3'末端プロセシングにおけるポリ(A)付加サイト選択の作用機序の解明","第３７回染色体ワークショップ・第１８回核ダイナミクス研究会",,,,,,2019,Dec.
"高橋秀尚,Amol Ranjan,鈴木 秀文,阿部 竜太,廣瀬 智威,佐々木 和教,山口 雄輝,中山 敬一,Joan Conaway,Ronald Conaway,畠山 鎮次","メディエーター複合体による転写終結制御機構の解明","第４２回日本分子生物学会年会",,,,,,2019,Dec.
"山口 雄輝,瑞慶覧 安里,Muhamad Fajar,舘野 峻平,高森 朝浩","Pol IIの転写終結部位を制御する分子機構","第４２回日本分子生物学会年会",,,,,,2019,Dec.
"山口 雄輝","E3ユビキチンリガーゼを標的とした創薬の新展開","東工大創薬ゲノムシンポジウム",,,,,,2019,Nov.
"Asatsuma-Okumura T,Ando H,De Simone M,Yamamoto J,Sato T,Shimizu N,Asakawa K,Yamaguchi Y,Takumi Ito,Guerrini L,Hiroshi Handa","p63 is a cereblon substrate involved in thalidomide teratogenicity",,"Nature Chemical Biology",,,"  15","Page 1077?1084",2019,Oct.
"Yuki Yamaguchi","Comprehensive identification of proximal proteins by in situ biotinylation through a specific antibody: toward proteomic analysis of liquid droplets","第９２回日本生化学会大会",,,,,,2019,Sept.
"Ando, H.,Sato, T.,Ito, T.,Yamamoto, J.,Sakamoto, S.,Nitta, N.,Asatsuma-Okumura, T.,Shimizu, N.,Mizushima, R.,Aoki, I.,Imai, T.,Yamaguchi, Y.,Berk, A.J.,Hiroshi Handa","Cereblon Control of Zebrafish Brain Size by Regulation of Neural Stem Cell Proliferation",,"iScience",,,,,2019,Apr.
"Hidefumi Suzuki,Mayumi Okamoto-Katsuyama,Tetsufumi Suwa,Ryo Maeda,Taka-aki Tamura,Yuki Yamaguchi","TLP-mediated global transcriptional repression after double-strand DNA breaks slows down DNA repair and induces apoptosis",,"Scientific Reports",,"  9","  1","  4868",2019,Mar.
"小泉 純玲,坂本 聡,山口 雄輝","抗がん作用を有するカンナビノイドの作用機序の解析","日本薬学会第139年会",,,,,,2019,Feb.
"Yasuaki kabe,Satoshi Sakamoto,Mamoru Hatakeyama,Yuki Yamaguchi,Makoto Suematsu,Makoto Itonaga,Hiroshi Handa","Application of high-performance magnetic nano-beads to biological sensing devices",,"Anal. Bioanal. Chem.",,"Vol. 411",,"p. 1825-1837",2019,Jan.
"Yuki Yamaguchi","Molecular mechanisms controlling pathways and sites for Pol ? transcription termination","第４１回日本分子生物学会年会",,,,,,2018,Nov.
"水止 洋孝,新垣 貴之,山口 雄輝","In situでのビオチン化反応を利用したタンパク質間相互作用の解析","第４１回日本分子生物学会年会",,,,,,2018,Nov.
"諏訪 哲史,鈴木 秀文,奥田 昌彦,西村 善文,山口 雄輝","TFIIH の多機能性を司るPleckstrin homology ドメインと新規標的因子の機能構造解析","第４１回日本分子生物学会年会",,,,,,2018,Nov.
"Tomoyuki Mori,Takumi Ito,Shujie Liu,Hideki Ando,Satoshi Sakamoto,Yuki Yamaguchi,Etsuko Tokunaga,Norio Shibata,Hiroshi Handa","Structural basis of thalidomide enantiomer binding to cereblon",,"Scientific Reports",,"  8","  1","  1294",2018,Jan.
"山本 淳一,Fajar Muhamad,瑞慶覧 安里,舘野 峻平,半田宏,山口 雄輝","NELFを中心としたポリ(A)付加部位の選択機構の解析","２０１７年度生命科学系学会合同年次大会",,,,,,2017,Dec.
"高橋 秀尚,柴田 美音,瀧川 一学,渡部 昌,築山 忠維,山本 淳一,山口 雄輝,藤井聡,飯田緑,Amol Ranjan,Shigeo Sato,Chieri Tomomori-Sato,Joan Conaway,Ronald Conaway,畠山 鎮次","メディエーター複合体による転写終結制御機構","２０１７年度生命科学系学会合同年次大会",,,,,,2017,Dec.
"舘野 峻平,Thiengtrong Benjarat,山口 雄輝","snRNAプロセシング因子Integrator複合体の分子構造解析","２０１７年度生命科学系学会合同年次大会",,,,,,2017,Dec.
"Fajar Muhamad,Ari Zukeran,Shunpei Tateno,Junichi Yamamoto,Hiroshi Handa,Yuki Yamaguchi","Mechanisms that affect post-transcriptional fate of RNA polymerase II-transcribed genes","２０１７年度生命科学系学会合同年次大会",,,,,,2017,Dec.
"鈴木 翔子,柴田 紘孝,山口 雄輝","マウスES細胞における2細胞期特異的遺伝子Zscan4の転写制御機構の解明","２０１７年度生命科学系学会合同年次大会",,,,,,2017,Dec.
"鈴木 秀文,前田 亮,木村 宏,浦 聖恵,田村 隆明,山口 雄輝","DNA損傷応答における転写抑制メカニズムとその生理的意義の解析","２０１７年度生命科学系学会合同年次大会",,,,,,2017,Dec.
"Hidefumi Suzuki,Ryo Maeda,Hiroshi Kimura,Kiyoe Ura,Taka-aki Tamura,Yuki Yamaguchi","Transcription silencing by TLP contributes to etoposide-induced apoptosis","Mechanisms of Eukaryotic Transcription  2017",,,,,,2017,Aug.
"Shunpei Tateno,Ari Zukeran,Junichi Yamamoto,Yuki Yamaguchi","Molecular mechanisms for polyadenylation site selection by NELF and related factors","Mechanisms of Eukaryotic Transcription  2017",,,,,,2017,Aug.
"山口 雄輝","転写反応の生化学",,"生体の科学",,"vol. 68","no. 3","p. 233-236",2017,July
"田村隆明,浦聖恵,山口雄輝","遺伝子発現制御機構 クロマチン，転写制御，エピジェネティクス",,"遺伝子発現制御機構 クロマチン，転写制御，エピジェネティクス","東京化学同人",,,,2017,Apr.
"坂本 聡,Gupta Vipul,劉 舒捷,安藤秀樹,舘野峻平,金子裕生,湯上真人,石井亮平,濡木 理,山口雄輝,半田 宏","抗炎症薬サリチル酸が示す生体内作用メカニズムの解析","日本化学会年第97春季年会",,,,,,2017,Mar.
"鈴木 翔子,柴田 紘孝,山口 雄輝","マウスES細胞における2細胞期特異的な遺伝子の発現制御メカニズムの解析","新学術領域研究「転写サイクル」冬の若手ワークショップ2017",,,,,,2017,Jan.
"舘野 峻平,飯田 緑,藤井 聡,佐倉 絵里,山口 雄輝","多発性骨髄腫における Pomalidomide 標的因子の網羅的探索","新学術領域研究「転写サイクル」冬の若手ワークショップ2017",,,,,,2017,Jan.
"鈴木秀文,前田 亮,木村 宏,浦聖恵,山口 雄輝,田村隆明","DNA損傷時に誘導される転写制御の生理的意義とTLPの役割","新学術領域研究「転写サイクル」冬の若手ワークショップ2017",,,,,,2017,Jan.
"坂本 聡,山口 雄輝,半田宏","ターゲット因子の解析を基盤とする生物活性物質が示す作用機構の解明","新学術領域研究「転写サイクル」冬の若手ワークショップ2017",,,,,,2017,Jan.
"徳山 遥香,片山 美樹,山口 雄輝","E3ユビキチンリガーゼCRBNの細胞内局在が免疫調整薬IMiDsの薬効に及ぼす影響","新学術領域研究「転写サイクル」冬の若手ワークショップ2017",,,,,,2017,Jan.
"瑞慶覧 安里,舘野 峻平,山本淳一,山口 雄輝","ＲＮＡポリメラーゼ?転写産物の長さを決める３’末端プロセシングの制御メカニズムの解明","新学術領域研究「転写サイクル」冬の若手ワークショップ2017",,,,,,2017,Jan.
"瑞慶覧 安里,山本 淳一,山口 雄輝","How Pol II termination and 3' processing sites are precisely determined in higher eukaryotes.高等真核生物においてPol IIの転写終結と3'プロセシングの部位はいかにして正確に決定されるのか","第39回日本分子生物学会年会",,,,,,2016,Nov.
"Shinnnosuke Kunimi,Yuma Ito,Yuki Yamaguchi,Kumiko Sakata-Sogawa,Makio Tokunaga","Quantitative image analysis of dynamics of promoter-proximal pausing related proteins","The 54th Annual Meeting of the Biophysical Society of Japan",,,,,,2016,Nov.
"瑞慶覧 安里,山本 淳一,山口 雄輝","NELFを中心としたポリ(A)付加部位選択のメカニズム","第39回日本分子生物学会年会",,,,,,2016,Nov.
"瑞慶覧 安里,舘野 峻平,山本淳一,山口 雄輝","NELFを中心としたポリ(A)付加部位選択のメカニズム","新学術領域研究「転写サイクル」班会議2016",,,,,,2016,Sept.
"鈴木秀文,前田 亮,浦聖恵,木村 宏,山口 雄輝,田村隆明","ＴＢＰ類似因子ＴＬＰによるＤＮＡ損傷応答時の転写抑制と細胞死誘導機構の解析","新学術領域研究「転写サイクル」班会議2016",,,,,,2016,Sept.
"瑞慶覧 安里,長谷川 冴妃子,舘野 峻平,山本淳一,山口 雄輝","高等真核生物においてPOL ?の転写終結と3'プロセシングの部位はいかにして正確に決定されるのか","新学術領域研究「転写サイクル」班会議2016",,,,,,2016,Sept.
"伊藤 拓水,朝妻 知子,山本 淳一,安藤 秀樹,佐藤 智美,山口 雄輝,半田 宏","リガンド依存的ユビキチンリガーゼＣＲＢＮの制御機構","日本ケミカルバイオロジー学会第11回年会",,,,,,2016,June
"坂本 聡,伊藤 拓水,森 智行,安藤 秀樹,山口 雄輝,箱嶋 敏雄,半田 宏","CRBNに対するサリドマイド光学異性体の結合基盤解析","日本ケミカルバイオロジー学会第11回年会",,,,,,2016,June
"Yasuaki Kabe,Takanori Nakane,Ikko Koike,Tatsuya Yamamoto,Yuki Sugiura,Erisa Harada,Kenji Sugase,Tatsuro Shimamura,Mitsuyo Ohmura,Kazumi Muraoka,Ayumi Yamamoto,Takeshi Uchida,So Iwata,Yuki Yamaguchi,Elena Krayukhina,Masanori Noda,Hiroshi Handa,Koichiro Ishimori,Susumu Uchiyama,Takuya Kobayashi,Makoto Suematsu","Haem-dependent dimerization of PGRMC1/sigma-2 receptor facilitates cancer proliferation and chemoresistance",,"Nat. Commun.",,"Vol. 7",,"pp. 11030",2016,Mar.
"外山 黛,荻原 裕里,Thiengtrong Benjarat,山口 雄輝","snRNA3'末端プロセシング因子インテグレーターの構造・機能解析","新学術領域研究「転写サイクル」冬の若手ワークショップ2016",,,,,,2016,Feb.
"山口 雄輝,伊藤拓水,山本淳一,半田宏","サリドマイドの多様な薬理作用の分子メカニズム","新学術領域研究「転写サイクル」冬の若手ワークショップ2016",,,,,,2016,Feb.
"鈴木 翔子,柴田 紘孝,山口 雄輝","マウスES細胞における2細胞期特異的な遺伝子の発現制御メカニズムの解析","新学術領域研究「転写サイクル」冬の若手ワークショップ2016",,,,,,2016,Feb.
"徳山 遥香,新垣 貴之,山口雄輝","サリドマイド標的タンパク質CRBNの相互作用因子の探索","新学術領域研究「転写サイクル」冬の若手ワークショップ2016",,,,,,2016,Feb.
"瑞慶覧 安里,山本 淳一,磯部 智康,山口 雄輝","NELFを中心としたRNAの品質管理のメカニズム","新学術領域研究「転写サイクル」冬の若手ワークショップ2016",,,,,,2016,Feb.
"新垣 貴之,徳山 遥香,山口 雄輝","Pol?複合体をモデルとしたタンパク質間相互作用の実験系の評価","新学術領域研究「転写サイクル」冬の若手ワークショップ2016",,,,,,2016,Feb.
"佐倉 絵里,舘野 峻平,山口 雄輝","新規抗がん剤の作用機構の解明","新学術領域研究「転写サイクル」冬の若手ワークショップ2016",,,,,,2016,Feb.
"舘野 峻平,飯田緑,藤井聡,山口 雄輝","多発性骨髄腫におけるPomalidomide標的因子の網羅的探索","新学術領域研究「転写サイクル」冬の若手ワークショップ2016",,,,,,2016,Feb.
"Satoshi Sakamoto,Takumi Ito,Yuki Yamaguchi,Hideki Ando,Hiroshi Handa","Biochemical analyses of CRBN, the target protein for immunomodulatory drugs (IMiDs)","PACIFCHEM2015",,,,,,2015,Dec.
"舘野 峻平,飯田緑,藤井聡,山口 雄輝","多発性骨髄腫に対するポマリドマイドの標的因子の網羅的探索","第３８回日本分子生物学会年会",,,,,,2015,Dec.
"Satoshi Sakamoto,Yuki Yamaguchi,Takumi Ito,Hiroshi Handa","Elucidation of the molecular mechanisms of action of bioactive natural products using high performance affinity beads","PACIFCHEM2015",,,,,,2015,Dec.
"山口雄輝","Ｐｏｌ?の転写伸長と運命決定制御のメカニズム","第２回北陸エピジェネティクス研究会",,,,,,2015,Nov.
"Qing-Fu Cao,Junichi Yamamoto,Tomoyasu Isobe,Shunpei Tateno,Yuki Murase,Yexi Chen,Hiroshi Handa,Yuki Yamaguchi","Characterization of the human transcription elongation factor Rtf1: evidence for non-overlapping functions of Rtf1 and the Paf1 complex",,"Mol. Cell. Biol.",,"Vol. 35","No. 20","pp. 3459-3470",2015,Oct.
"Clelia Laitem,Justyna Zaborowska,Michael Tellier,Yuki Yamaguchi,Seifuku Sou,Sylvain Egloff,Hiroshi Handa,Shona Murphy","CTCF regulates NELF, DSIF and P-TEFb recruitment during transcription",,"Transcription",,"Vol. 6","No. 5","pp. 79-90",2015,Sept.
"瑞慶覧 安里,山本 淳一,磯部智康,山口 雄輝","NELFを中心としたmRNAの品質管理のメカニズム","新学術領域研究「転写サイクル」班会議2015",,,,,,2015,Aug.
"Yuki Yamaguchi,Junichi Yamamoto","Regulatory Mechanisms for Pol II Termination Sites and 3' Processing Pathways in Higher Eukaryotes","MECHANISM OF EUKARYOTIC TRANSCRIPTION",,,,,,2015,Aug.
"山口 雄輝,磯部智康,曹 青福,山本 淳一","転写伸長段階の制御メカニズム：新たな制御因子の探索","新学術領域研究「転写サイクル」班会議2015",,,,,,2015,Aug.
"磯部智康,山口 雄輝","転写伸張因子DSIFのCTRを介した転写制御機構の解析","新学術領域研究「転写サイクル」班会議2015",,,,,,2015,Aug.
"坂本 聡,伊藤 拓水,安藤 秀樹,山口 雄輝,半田 宏","IMiDs標的タンパク質CRBNの生化学的解析","日本ケミカルバイオロジー学会第１０回年会",,,,,,2015,June
"坂本 聡,山口雄輝,半田 宏","アフィニティビーズを利用した生物活性物質標的タンパク質の単離・同定・評価","日本薬学会第135年会",,,,,,2015,Mar.
"Masa-aki Kawano,Koji Doi,Hajime Fukuda,Yoshinori Kita,Imai Kensuke,Takamasa Inoue,Teruya Enomoto,Masanori Matsui,Mamoru Hatakeyama,Yuki Yamaguchi,Hiroshi Handa","SV40 VP1 major capsid protein in its self-assembled form allows VP1 pentamers to coat various types of artificial beads in vitro regardless of their sizes and shapes",,"Biotechnol. Rep.",,"Vol. 5",,"pp. 105-111",2015,Mar.
"磯部智康,千葉 国俊,山口 雄輝","転写伸長因子DSIFのリン酸化の転写伸長反応への寄与の解析","新学術領域研究「転写サイクル」冬の若手ワークショップ2015",,,,,,2015,Feb.
"山本淳一,半田宏,山口 雄輝","DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes","新学術領域研究「転写サイクル」冬の若手ワークショップ2015",,,,,,2015,Feb.
"片山 美樹,伊藤拓水,安藤 秀樹,山口 雄輝,半田宏","E3ユビキチンリガーゼの基質認識レセプター CRBNとポマリドマイド依存的な基質Aiolosの生化学的解析","第３７回日本分子生物学会年会",,,,,,2014,Nov.
"Kyota Ko,Simon Gillett,近藤 科江,山口 雄輝","理系英会話アクティブラーニング1 テツヤ、国際学会いってらっしゃい",,,"羊土社",,,,2014,Nov.
"Yuki Yamaguchi,Junichi Yamamoto","Regulatory Mechanisms for Pol II Termination Sites and 3' Processing Pathways in Higher Eukaryotes","新学術領域研究「転写サイクル」国際シンポジウム2014",,,,,,2014,Nov.
"Kyota Ko,Simon Gillett,近藤 科江,山口 雄輝","理系英会話アクティブラーニング2 テツヤ、ディスカッションしようか",,,"羊土社",,,,2014,Nov.
"山口雄輝,成田央","基礎からしっかり学ぶ生化学",,,"羊土社",,,,2014,Oct.
"半田宏,山口雄輝","新しい遺伝子工学 新版",,,"朝倉書店",,,,2014,Sept.
"柴田 紘孝,半田宏,山口 雄輝","転写伸長因子DSIFおよびNELFがES細胞の多分化能維持に果たす役割","新学術領域研究「転写サイクル」班会議2014",,,,,,2014,Aug.
"磯部智康,千葉 国俊,山口 雄輝","転写伸長因子DSIFにリン酸化依存的に相互作用する因子の機能解析","新学術領域研究「転写サイクル」班会議2014",,,,,,2014,Aug.
"山本淳一,半田宏,山口雄輝","DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes","新学術領域研究「転写サイクル」班会議2014",,,,,,2014,Aug.
"曹 青福,陳 業熹,半田 宏,山口 雄輝","新規転写伸長因子ヒトRtf1が関与する転写制御の分子機構","新学術領域研究「転写サイクル」班会議2014",,,,,,2014,Aug.
"山口雄輝,山本淳一,半田宏","ヒトRNA ポリメラーゼII 転写産物のプロセシング経路の選択機構","新学術領域研究「転写サイクル」班会議2014",,,,,,2014,Aug.
"Junichi Yamamoto,Yuri Hagiwara,Kunitoshi Chiba,Tomoyasu Isobe,Takashi Narita,Hiroshi Handa,Yuki Yamaguchi","DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes.",,"Nat. Commun.",,"Vol. 5",,"pp. 4263",2014,June
"坂本 聡,Vipul Gupta,劉 舒捷,安藤 秀樹,舘野 峻平,金子 裕生,湯上 真人,石井 亮平,濡木 理,山口 雄輝,半田 宏","抗炎症薬サリチル酸の生体内作用機構の解析","日本ケミカルバイオロジー学会第９回年会",,,,,,2014,June
"Misao Takemoto,Yumi Kawamura,Mikako Hirohama,Yuki Yamaguchi,Hiroshi Handa,Hisato Saitoh,Yoichi Nakao,Manabu Kawada,Khan Khalid,Hiroyuki Koshino,Ken-ichi Kimura,Akihiro Ito,Minoru Yoshida","Inhibition of protein SUMOylation by davidiin, an ellagitannin from Davidia involucrata",,"J. Antibiot.",,"Vol. 67","No. 4","pp. 335-338",2014,Apr.
"坂本 聡,唐澤 慧記,東 基記,笠間 健嗣,宮澤 啓介,山口 雄輝,半田 宏","ビタミンK2が引き起こすがん細胞のアポトーシス誘導機構の解析","日本化学会第９４春季年会",,,,,,2014,Mar.
"飯田緑,舘野 峻平,山口 雄輝,藤井聡","Cellecta社製プール型レンチウイルスshRNAライブラリーを用いたスクリーニングデータ解析法の検討","新学術領域「転写サイクル」冬の若手ワークショップ2014",,,,,,2014,Jan.
"曹 青福,陳 業熹,半田 宏,山口 雄輝","転写伸長因子ヒトPaf1複合体が関与する転写制御の分子機構","新学術領域研究「転写サイクル」冬の若手ワークショップ2014",,,,,,2014,Jan.
"舘野 峻平,山口 雄輝","多発性骨髄腫に対するポマリドマイドの標的因子の網羅的探索","新学術領域研究「転写サイクル」冬の若手ワークショップ2014",,,,,,2014,Jan.
"Satoshi Sakamoto,Kenshi Omagari,Yoshinori Kita,Yusuke Mochizuki,Yasuyuki Naito,Shintaro Kawata,Sachiko Matsuda,Osamu Itano,Hiromitsu Jinno,Hiroya Takeuchi,Yuki Yamaguchi,Yuko Kitagawa,Hiroshi Handa","Magnetically Promoted Rapid Immunoreactions Using Functionalized Fluorescent Magnetic Beads: A Proof of Principle",,"Clinical Chemistry","American Association for Clinical Chemistry","Vol. 60","No. 4","pp. 610-620",2014,Jan.
"中村 佳奈子,山口 雄輝","ゲノム上のRNAポリメラーゼ等の動的解析を目指した予備的な検討","新学術領域研究「転写サイクル」冬の若手ワークショップ2014",,,,,,2014,Jan.
"長谷川 冴妃子,千葉 国俊,磯部智康,山口 雄輝","転写伸長因子DSIFにリン酸化依存的に相互作用する因子の機能解析","新学術領域研究「転写サイクル」冬の若手ワークショップ2014",,,,,,2014,Jan.
"柴田 紘孝,半田 宏,山口 雄輝","転写伸長因子DSIFおよびNELFがES細胞の多分化能維持に果たす役割","新学術領域研究「転写サイクル」冬の若手ワークショップ2014",,,,,,2014,Jan.
"飯田 結,伊藤 拓水,安藤 秀樹,山口 雄輝,半田 宏","サリドマイドターゲット分子CRBN の生化学的解析","第３６回日本分子生物学会年会",,,,,,2013,Dec.
"中村 佳奈子,山口 雄輝","ゲノム上のRNA ポリメラーゼ等のカイネティクス解析を目指した予備的な検討","第３６回日本分子生物学会年会",,,,,,2013,Dec.
"舘野 峻平,山口 雄輝","多発性骨髄腫に対するポマリドマイドの標的因子の網羅的探索","第３６回日本分子生物学会年会",,,,,,2013,Dec.
"舩造 正英,伊藤 拓水,安藤 秀樹,山口 雄輝,半田 宏","多発性骨髄腫におけるCRBN 結合因子の探索及び解析","第３６回日本分子生物学会年会",,,,,,2013,Dec.
"Vipul Gupta,Shujie Liu,Hideki Ando,Ryohei Ishii,Shumpei Tateno,Yuki Kaneko,Masato Yugami,Satoshi Sakamoto,Yuki Yamaguchi,Osamu Nureki,Hiroshi Handa","Salicylic acid induces mitochondrial injury by inhibiting ferrochelatase heme biosynthesis activity",,"Mol. Pharmacol.",,"Vol. 84","No. 6","pp. 824-833",2013,Nov.
"Efrat Shema-Yaacoby,Miroslav Nikolov,Mahmood Haj-Yahya,Peter Siman,Eric Allemand,Yuki Yamaguchi,Christian Muchardt,Henning Urlaub,Ashraf Brik,Moshe Oren,Wolfgang Fischle","Systematic identification of proteins binding to chromatin-embedded ubiquitylated H2B reveals recruitment of SWI/SNF to regulate transcription",,"Cell Rep.",,"Vol. 4","No. 3","pp. 601-608",2013,Aug.
"Teruya Enomoto,Masa-aki Kawano,Hajime Fukuda,Wataru Sawada,Takamasa Inoue,Kok Chee Haw,Yoshinori Kita,Satoshi Sakamoto,Yuki Yamaguchi,Takeshi Imai,Mamoru Hatakeyama,Shigeyoshi Saito,Adarsh Sandhu,Masanori Matsui,Ichio Aoki,Hiroshi Handa","Viral protein-coating of magnetic nanoparticles using simian virus 40 VP1",,"J. Biotechnol.",,"Vol. 167","No. 1","pp. 8-15",2013,Aug.
"Tomoyasu Isobe,Soken-Nakazawa J. Song,Prabha Tiwari,Hiroki Ito,Yuki Yamaguchi,Kazuyuki Yoshizaki","Activation-induced cytidine deaminase auto-activates and triggers aberrant gene expression",,"FEBS Letters",,"Vol. 587","No. 16","pp. 2487-2492",2013,Aug.
"Kentaro Hotta,Akihiro Nashimoto,Eiji Yasumura,Masafumi Suzuki,Motoki Azuma,Yosuke Iizumi,Daisuke Shima,Ryusuke Nabeshima,Masaki Hiramoto,Akira Okada,Kumiko Sakata-Sogawa,Makio Tokunaga,Takumi Ito,Hideki Ando,Satoshi Sakamoto,Yasuaki Kabe,Shinichi Aizawa,Takeshi Imai,Yuki Yamaguchi,Hajime Watanabe,Hiroshi Handa","Vesnarinone suppresses TNFα mRNA expression by inhibiting valosin-containing protein",,"Mol. Pharmacol.",,"Vol. 83","No. 5","pp. 930-938",2013,May
"Jeff Kershaw,Christoph Leuze,Ichio Aoki,Takayuki Obata,Iwao Kanno,Hiroshi Ito,Yuki Yamaguchi,Hiroshi Handa","Systematic changes to the apparent diffusion tensor of in vivo rat brain measured with an oscillating-gradient spin-echo sequence",,"Neuroimage",,"Vol. 70",,"pp. 10-20",2013,Apr.
"Satoki Karasawa,Motoki Azuma,Takeshi Kasama,Satoshi Sakamoto,Yasuaki Kabe,Takeshi Imai,Yuki Yamaguchi,Keisuke Miyazawa,Hiroshi Handa","Vitamin K2 Covalently Binds to Bak and Induces Bak-Mediated Apoptosis",,"Molecular Pharmacology",,"Vol. 83","No. 3","pp. 613-620",2013,Mar.
"Yuki Yamaguchi,Hirotaka Shibata,Hiroshi Handa","Transcription elongation factors DSIF and NELF: Promoter-proximal pausing and beyond",,"Biochimica et Biophysica Acta. Gene Regulatory Mechanisms",,"Vol. 1829","No. 1","pp. 98-104",2013,Jan.
"Yuki Ito,Takumi Ito,Satoki Karasawa,Teruya Enomoto,Nashimoto, Akihiro,Hase, Yasuyoshi,Sakamoto, Satoshi,Mimori, Tsuneyo,Yoshihisa Matsumoto,Yuki Yamaguchi,HIROSHI HANDA","Identification of DNA-Dependent Protein Kinase Catalytic Subunit (DNA-PKcs) as a Novel Target of Bisphenol A",,"Plos One",,"Vol. 7","No. 12","p. e50481",2012,Dec.
"Gil Diamant,Liat Amir-Zilberstein,Yuki Yamaguchi,Hiroshi Handa,Rivka Dikstein","DSIF Restricts NF-κB Signaling by Coordinating Elongation with mRNA Processing of Negative Feedback Genes",,"Cell Reports",,"Vol. 2","No. 4","pp. 722?731",2012,Oct.
"Teruya Enomoto,Iwao Kukimoto,Masa-aki Kawano,Yuki Yamaguchi,Arnold J. Berk,Hiroshi Handa","In vitro reconstitution of SV40 particles that are composed of VP1/2/3 capsid proteins and nucleosomal DNA and direct efficient gene transfer",,"Virology",,"Vol. 420","No. 1","pp. 1-9",2011,Nov.
"Ayumi Kawano,Yohei Hayashi,Shuhei Noguchi,Hiroshi Handa,Masami Horikoshi,Yuki Yamaguchi","Global analysis for functional residues of histone variant Htz1 using the comprehensive point mutant library",,"Genes Cells",,"Vol. 16","No. 5","pp. 590-607",2011,Mar.
"Takuya Taneda,Wenyan Zhu,Qingfu Cao,Hajime Watanabe,Yuki Yamaguchi,Hiroshi Handa,Tadashi Wada","Erythropoiesis is regulated by the transcription elongation factor Foggy/Spt5 through gata1 gene regulation",,"Genes to Cells",,"  16","  2","  231?242",2011,Feb.
"伊藤 拓水,安藤 秀樹,山口雄輝,半田 宏","S16-4 サリドマイドによる催奇性の分子機構 : ナノビーズ技術を用いたアプローチ(シンポジウムS16 薬物有害反応の発現機構と予測の新展開,臨床から学び臨床へと還元する医療薬学)",,"日本医療薬学会年会講演要旨集","日本医療薬学会","Vol. 20",,"pp. 236",2010,Oct.
"Kunitoshi Chiba,Junichi Yamamoto,Yuki Yamaguchi,Hiroshi Handa","Promoter-proximal pausing and its release: molecular mechanisms and physiological functions",,"Exp. Cell Res.",,"Vol. 316","No. 17","p. 2723-2730",2010,Oct.
"Sol Kim,Junichi Yamamoto,Yexi Chen,Masatoshi Aida,Tadashi Wada,Hiroshi Handa,Yuki Yamaguchi","Evidence that cleavage factor Im is a heterotetrameric protein complex controlling alternative polyadenylation",,"Genes Cells",,"Vol. 15","No. 9","p. 1003-1013",2010,Sept.
"Kanako Kume,Yosuke Iizumi,Masashi Shimada,Yuki Ito,Tsutomu Kishi,Yuki Yamaguchi,Hiroshi Handa","Role of N-end rule ubiquitin ligases UBR1 and UBR2 in regulating the leucine-mTOR signaling pathway",,"Genes Cells",,"Vol. 15","No. 4","p. 339-349",2010,Apr.
"Takumi Ito,Hideki Ando,Takayuki Suzuki,Toshihiko Ogura,Kentaro Hotta,Yoshimasa Imamura,Yuki Yamaguchi,Hiroshi Handa","Identification of a primary target of thalidomide teratogenicity",,"Science",,"Vol. 327","No. 5971","p. 1345-1350",2010,Mar.
"山口雄輝","転写伸長研究の新展開",,"生化學","日本生化学会","Vol. 82","No. 3","pp. 210-220",2010,Mar.
"Yuka Masaike,Takeshi Takagi,Masataka Hirota,Joe Yamada,Satoru Ishihara,Tetsu M. C. Yung,Takamasa Inoue,Chika Sawa,Hiroshi Sagara,Satoshi Sakamoto,Yasuyuki Takahashi,Yuki Yamaguchi,Hiroshi Handa,Yasuaki Kabe","Identification of Dynamin-2-Mediated Endocytosis as a New Target of Osteoporosis Drugs, Bisphosphonates",,"Molecular Pharmacology",,"Vol. 77","No. 2","pp. 262-269",2010,Feb.
"Yexi Chen,Yuki Yamaguchi,Yuta Tsugeno,Junichi Yamamoto,Tomoko Yamada,Mitsuhiro Nakamura,Koji Hisatake,Hiroshi Handa","DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation",,"Genes Dev.",,"  23","  23","  2765-2777",2009,Dec.
"Hui Chen,Xavier Contreras,Yuki Yamaguchi,Hiroshi Handa,B. Matija Peterlin,Su Guo","Repression of RNA Polymerase II elongation in vivo is critically dependent on the C-terminus of Spt5",,"PLoS ONE",,"Vol. 4","No. 9","p. e6918",2009,Sept.
"Hiroyuki Kamiya,Akihiro Suzuki,Yuki Yamaguchi,Hiroshi Handa,Hideyoshi Harashima","Incorporation of 8-hydroxyguanosine (8-oxo-7,8-dihydroguanosine) 5'-triphosphate by bacterial and human RNA polymerases",,"Free Radic. Biol. Med.",,"  46","  12","  1703-1707",2009,June
"Tetsu M. C. Yung,Takashi Narita,Toshiharu Komori,Yuki Yamaguchi,Hiroshi Handa","Cellular dynamics of the negative transcription elongation factor NELF",,"Exp. Cell Res.",,"  315","  10","  1693-1705",2009,June
"Chikanori Kuramori,Yasuyoshi Hase,Koichi Hoshikawa,Keiko Watanabe,Takeyuki Nishi,Takako Hishiki,Tomoyoshi Soga,Akihiro Nashimoto,Yasuaki Kabe,Yuki Yamaguchi,Hajime Watanabe,Kohsuke Kataoka,Makoto Suematsu,Hiroshi Handa","Mono-(2-ethylhexyl) phthalate targets glycogen debranching enzyme and affects glycogen metabolism in rat testis",,"Toxicol. Sci.",,"  109","  1","  143-151",2009,May
"Toshiharu Komori,Naoto Inukai,Tomoko Yamada,Yuki Yamaguchi,Hiroshi Handa","Role of human transcription elongation factor DSIF in the suppression of senescence and apoptosis",,"Genes Cells",,"  14","  3","  343-354",2009,Mar.
"Chikanori Kuramori,Motoki Azuma,Kanako Kume,Yuki Kaneko,Atsushi Inoue,Yuki Yamaguchi,Yasuaki Kabe,Takamitsu Hosoya,Masahiro Kizaki,Makoto Suematsu,Hiroshi Handa","Capsaicin binds to prohibitin 2 and displaces it from the mitochondria to the nucleus",,"Biochem. Biophys. Res. Commun.",,"  379","  2","  519-525",2009,Feb.
"Satoshi Sakamoto,Yasuaki Kabe,Mamoru Hatakeyama,Yuki Yamaguchi,Hiroshi Handa","Development and application of high-performance affinity beads: toward chemical biology and drug discovery",,"Chem. Rec.",,"  9","  1","  66-85",2009,
"山口雄輝,半田宏","転写制御とエピジェネティクス?ゲノムデコードに向けて",,,"南山堂",,,,2008,Dec.
"Motoki Azuma,Yasuaki Kabe,Chikanori Kuramori,Masao Kondo,Yuki Yamaguchi,Hiroshi Handa","Adenine nucleotide translocator transports haem precursors into mitochondria",,"PLoS One",,"  3","  8","  e3070",2008,Aug.
"Kozue Ando,Satoshi Hirao,Yasuaki Kabe,Yuji Ogura,Iwao Sato,Yuki Yamaguchi,Tadashi Wada,Hiroshi Handa","A new APE1/Ref-1-dependent pathway leading to reduction of NF-kappaB and AP-1, and activation of their DNA-binding activity",,"Nucleic Acids Res.",,"  36","  13","  4327-4336",2008,Aug.
"Ryou-u Takahashi,Shin-nosuke Kanesashi,Takamasa Inoue,Teruya Enomoto,Masa-aki Kawano,Hiroko Tsukamoto,Fumitaka Takeshita,Takeshi Imai,Takahiro Ochiya,Kohsuke Kataoka,Yuki Yamaguchi,Hiroshi Handa","Presentation of functional foreign peptides on the surface of SV40 virus-like particles",,"J. Biotechnol.",,"  135","  4","  385-392",2008,July
"Masafumi Suzuki,Shoichiro Furukawa,Chikanori Kuramori,Chika Sawa,Yasuaki Kabe,Mitsuhiro Nakamura,Jun-ichi Sawada,Yuki Yamaguchi,Satoshi Sakamoto,Satoshi Inouye,Hiroshi Handa","Development of a chemical screening system using aqueorin-fused protein",,"Biochem. Biophys. Res. Commun.",,"  368","  3","  600-605",2008,Apr.
"Hase, Y.,Tatsuno, M.,Nishi, T.,Kataoka, K.,Kabe, Y.,Yamaguchi, Y.,Ozawa, N.,Natori, M.,Handa, H.,Watanabe, H.","Atrazine binds to F1F0-ATP synthase and inhibits mitochondrial function in sperm",,"Biochem. Biophys. Res. Commun.",,"Vol. 366","No. 1","pp. 66-72",2008,Feb.
"山口雄輝,半田宏","細胞周期依存的なヒストンの発現機構",,"蛋白質核酸酵素","共立出版","Vol. 52","No. 14","pp. 1857-1862",2007,Nov.
"Tsukamoto, H.,Kawano, M.,Inoue, T.,Enomoto, T.,Takahashi, R.,Yokoyama, N.,Yamamoto, N.,Imai, T.,Kataoka, K.,Yamaguchi, Y.,Handa, H.","Evidence that SV40 VP1-DNA interactions contribute to the assembly of 40-nm spherical viral particles",,"Genes Cells",,"Vol. 12","No. 11","pp. 1267-1279",2007,Nov.
"Amir-Zilberstein, L.,Ainbinder, E.,Taube, L.,Yamaguchi, Y.,Handa, H.,Dikstein, R.","Differential regulation of NF-kB by elongation factors is determined by core promoter type",,"Mol. Cell. Biol.",,"Vol. 27","No. 14","pp. 5246-5259",2007,July
"Yamaguchi, Y.,Mura, T.,Chanarat, T.,Okamoto, S.,Handa, H.","Hepatitis delta antigen binds to the clamp of RNA polymerase II and affects transcriptional fidelity",,"Genes Cells",,"Vol. 12","No. 7","pp. 863-875",2007,July
"Zhu, W.,Wada, T.,Okabe, S.,Taneda, T.,Yamaguchi, Y.,Handa, H.","DSIF contributes to transcriptional activation by DNA-binding activators by preventing pausing during transcription elongation",,"Nucleic Acids Res.",,"Vol. 35","No. 12","pp. 4064-4075",2007,June
"山口雄輝,半田宏,和田忠士","転写因子による生命現象解明の最前線：実験医学増刊 25",,,"シュプリンガー・フェアラーク",,,,2007,June
"Takashi Narita,Yung, T.M.C.,Junichi Yamamoto,Tsuboi, Y.,Tanabe, H.,Tanaka, K.,Yamaguchi, Y.,HIROSHI HANDA,,","NELF interacts with CBC and participates in 3'-end processing of replication-dependent histone mRNAs",,"Mol. Cell",,"Vol. 26","No. 3","pp. 349-365",2007,May
"Nishio, K.,Gokon, N.,Hasegawa, M.,Ogura, Y.,Ikeda, M.,Narimatsu, H.,Tada, M.,Yamaguchi, Y.,Sakamoto, S.,Abe, M.,Handa, H.","Identification of a chemical substructure that is immobilized to ferrite nanoparticles (FP)",,"Colloids Surf. B. Biointerfaces.",,"Vol. 54","No. 21","pp. 249-253",2007,Feb.
"Yamamoto, N.,Suzuki, M.,Kawano, M.,Inoue, T.,Takahashi, R.,Tsukamoto, H.,Enomoto, T.,Yamaguchi, Y.,Wada, T.,Handa, H.","Adeno-associated virus site-specific integration is regulated by TRP-185",,"J. Virol.",,"Vol. 81","No. 4","pp. 1990-2001",2007,Feb.
"Yugami, M.,Kabe, Y.,Yamaguchi, Y.,Wada, T.,Handa, H.","hnRNP-U enhances the expression of specific genes by stabilizing mRNA.",,"FEBS Lett.",,"Vol. 581","No. 1","pp. 1-7",2007,Jan.
"Kubo, T.,Wada, T.,Yamaguchi, Y.,Shimizu, A.,Handa, H.","Knock-down of 25-kDa subunit of cleavage factor Im in HeLa cells alters alternative polyadenylation within 3' UTRs",,"Nucleic Acid Res.",,"Vol. 34","No. 21","pp. 6264-6271",2006,Dec.
"Hitoshi Uga,Chikanori Kuramori,Akiko Ohta,Yasunori Tsuboi,Hiroshi Tanaka,Mamoru Hatakeyama,Yuki Yamaguchi,Masahiro Kizaki,Takashi Takahashi,Hiroshi Handa","A new mechanism of methotrexate action revealed by target screening with affinity beads",,"Mol. Pharmacol.",,"Vol. 70","No. 5","pp. 1832-1839",2006,Aug.
"Aida, M.,Chen, Y.,Nakajima, K.,Yamaguchi, Y.,Wada, T.,Handa, H.","Transcriptional pausing caused by NELF plays a dual role in regulating immediate-early expression of the junB gene",,"Mol. Cell. Biol.",,"Vol. 26","No. 16","pp. 6094-6104",2006,Aug.
"Ogura, Y.,Azuma, M.,Tsuboi, Y.,Kabe, Y.,Yamaguchi, Y.,Wada, T.,Watanabe, H.,Handa, H.","TFII-I down-regulates a subset of estrogen-responsive genes through its interaction with an initiator element and estrogen receptor α",,"Genes Cell",,"Vol. 11","No. 4","pp. 373-381",2006,Apr.
"Yamada, T.,Yamaguchi, Y.,Inukai, N.,Kamijo, S.,Mura, T.,Handa, H.","P-TEFb-mediated phosphorylation of the hSpt5 C-terminal repeats is critical to processive transcription elongation",,"Mol. Cell",,"Vol. 21","No. 2","pp. 227-237",2006,Jan.
"Handa, Y.,Yamaguchi, Y.","Hepatitis Delta Virus",,,"Landes Bioscience / Springer Science+Business Media",,,,2006,
"山口雄輝","ケミカルバイオロジー・ケミカルゲノミクス",,,"シュプリンガー・フェアラーク",,,,2005,Nov.
"山口雄輝","転写研究集中マスター",,,"羊土社",,,,2005,Sept.
"Delehouzee, S.,Yoshikawa, T.,Sawa, C.,Sawada, J.,Ito, T.,Omori, M.,Wada, T.,Yamaguchi, Y.,Kabe, Y.,Handa, H.","GABP, HCF-1 and YY1 are involved in Rb gene expression during myogenesis",,"Genes Cells",,"Vol. 10","No. 7","pp. 717-731",2005,July
"Azuma, N.,Tadokoro, K.,Asaka, A.,Yamada, M.,Yamaguchi, Y.,Handa, H.,Matsushima, S.,Watanabe, T.,Kida, Y.,Ogura, T.,Shimamura, K.,Nakafuku, M.","Transdifferentiation of the retinal pigment epithelia to the neural retina by transfer of the Pax6 transcriptional factor",,"Hum. Mol. Genet.",,"Vol. 14","No. 8","pp. 1059-1068",2005,Apr.
"Ohtsu, Y.,Ohba, R.,Imamura, Y.,Kobayashi, M.,Hatori, H.,Zenkoh, T.,Hatakeyama, M.,Manabe, T.,Hino, M.,Yamaguchi, Y.,Kataoka, K.,Kawaguchi, H.,Watanabe, H.,Handa, H.","Selective ligand purification using high-performance affinity beads",,"Anal. Biochem.",,"Vol. 338","No. 2","pp. 245-252",2005,Mar.
"山口雄輝","科学英語論文の赤ペン添削講座",,,,,,,2005,Mar.
"Azuma, N.,Tadokoro, K.,Asaka, A.,Yamada, M.,Yamaguchi, Y.,Handa, H.,Matsushima, S.,Watanabe, T.,Kohsaka, S.,Kida, Y.,Shiraishi, T.,Ogura, T.,Shimamura, K.,Nakafuku, M.","The Pax6 isoform bearing an alternative spliced exon promotes the development of the neural retinal structure",,"Hum. Mol. Genet.",,"Vol. 14","No. 6","pp. 735-745",2005,Mar.
"Wang, G.,Balamotis, M.A.,Stevens, J.L.,Yamaguchi, Y.,Handa, H.,Berk, A.","Mediator requirement for both recruitment and post-recruitment steps in transcription initiation",,"Mol. Cell",,"Vol. 17","No. 5","pp. 683-694",2005,Mar.
"Wu,C.-H.,Lee, C.,Fan, R.,Smith, M.J.,Yamaguchi, Y.,Handa, H.,Gilmour, D.S.","Molecular characterization of Drosophila NELF",,"Nucleic Acids Res.",,"Vol. 33","No. 4","pp. 1269-1279",2005,Mar.
"Kabe, Y.,Yamada, J.,Uga, H.,Yamaguchi, Y.,Wada, T.,Handa, H.","NF-Y is essential for the recruitment of RNA polymerase II and inducible transcription of several CCAAT box-containing genes",,"Mol. Cell. Biol.",,"Vol. 25","No. 1","pp. 512-522",2005,Jan.
"Jennings, B.H.,Shah, S.,Yamaguchi, Y.,Seki, M.,Phillips, R.G.,Handa, H.,Ish-Horowicz, D.","Locus-specific requirements for Spt5 in transcriptional activation and repression in Drosophila",,"Curr. Biol.",,"Vol. 14","No. 18","pp. 1680-1684",2004,Sept.
"Aiyar, S.E.,Sun,J.-L.,Blair, A.L.,Moskaluk, C.A.,Lv, Y.,Ye,Q.-N.,Yamaguchi, Y.,Mukherjee, A.,Ren,D.-M.,Handa, H.,Li, R.","Attenuation of estrogen receptor α-mediated transcription through estrogen-stimulated recruitment of a negative elongation factor",,"Genes Dev.",,"Vol. 18","No. 17","pp. 2134-2146",2004,Sept.
"Oshima, S.,Nakamura, T.,Namiki, S.,Okada, E.,Tsuchiya, K.,Okamoto, R.,Yamazaki, M.,Yokota, T.,Aida, M.,Yamaguchi, Y.,Kanai, T.,Handa, H.,Watanab","Interferon regulatory factor 1 (IRF-1) and IRF-2 distinctively up-regulate gene expression and production of interleukin-7 in human intestinal epithelial cells",,"Mol. Cell. Biol.",,"Vol. 24","No. 14","pp. 6298-6310",2004,July
"Endou, M.,Zhu, W.,Hasegawa, J.,Watanabe, H.,Kim,D.-K.,Aida, M.,Inukai, N.,Narita, T.,Yamada, T.,Furuya, A.,Sato, H.,Yamaguchi, Y.,Mandal, S.S.,Rei","Human Spt6 stimulates transcription elongation by RNA polymerase II in vitro",,"Mol. Cell. Biol.",,"Vol. 24","No. 8","pp. 3324-3336",2004,Apr.
"Ainbinder, E.,Amir-Zilberstein, L.,Yamaguchi, Y.,Handa, H.,Dikstein, R.","Elongation inhibition by DRB sensitivity-inducing factor is regulated by the A20 promoter via a novel negative element and NF-κB",,"Mol. Cell. Biol.",,"Vol. 24","No. 6","pp. 2444-2454",2004,Mar.
"Inukai, N.,Yamaguchi, Y.,Kuraoka, I.,Yamada, T.,Kamijo, S.,Kato, J.,Tanaka, K.,Handa, H.","A novel hydrogen peroxide-induced phosphorylation and ubiquitination pathway leading to RNA polymerase II proteolysis",,"J. Biol. Chem.",,"Vol. 279","No. 9","pp. 8190-8195",2004,Feb.
"山口雄輝","キーワードで理解する転写イラストマップ",,"羊土社","羊土社",,,,2004,
"Azuma, N.,Yamaguchi, Y.,Handa, H.,Tadokoro, K.,Asaka, A.,Kawase, E.,Yamada, M.","Mutations of the PAX6 gene detected in patients with a variety of optic nerve malformations",,"Am. J. Hum. Genet.",,"Vol. 72","No. 6","pp. 1565-1570",2003,June
"Wu,C.-H.,Yamaguchi, Y.,Benjamin, L.R.,Horvat-Gordon, M.,Washinski, J.,Enerly, E.,Larsson, J.,Lambertsson, A.,Handa, H.,Gilmour, D.S.","NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila",,"Genes Dev.",,"Vol. 17","No. 11","pp. 1402-1414",2003,June
"Nedialkov, Y.A.,Gong, X.Q.,Hovde, S.L.,Yamaguchi, Y.,Handa, H.,Geiger, J.H.,Yan, H.,Burton, Z.F.","NTP-driven translocation by human RNA polymerase II",,"J. Biol. Chem.",,"Vol. 278","No. 20","pp. 18303-18312",2003,May
"Kim, D.,Inukai, N.,Yamada, T.,Furuya, A.,Sato, H.,Yamaguchi, Y.,Wada, T.,Handa, H.","Structure-function analysis of human Spt4: evidence that hSpt4 and hSpt5 exert their roles in transcriptional elongation as parts of the DSIF complex",,"Genes Cells",,"Vol. 8","No. 4","pp. 371-378",2003,Apr.
"Narita, T.,Yamaguchi, Y.,Yano, K.,Sugimoto, S.,Chanarat, S.,Wada, T.,Kim, D.,Hasegawa, J.,Omori, M.,Inukai, N.,Endoh, M.,Yamada, T.,Handa,H..","Human transcription elongation factor NELF: Identification of novel subunits and reconstitution of the functionally active complex",,"Mol. Cell. Biol.",,"Vol. 23","No. 6","pp. 1863-1873",2003,Mar.
"Shima, D.,Yugami, M.,Tatsuno, M.,Wada, T.,Yamaguchi, Y.,Handa, H.","Mechanism of H-8 inhibition of Cyclin-dependent kinase 9: study using inhibitor-immobilized matrices",,"Genes Cells",,"Vol. 8",,"pp. 215-223",2003,Mar.
"Kuraoka, I.,Endou, M.,Yamaguchi, Y.,Wada, T.,Handa, H.,Tanaka, K.","Effects of endogeneous DNA base lesions on transcription elongation by mammalian RNA polymerase II: Implications for transcription-coupled DNA repair and transcriptional mutagenesis",,"J. Biol. Chem.",,"Vol. 278",,"pp. 7294-7299",2003,Feb.
"Hasegawa, J.,Endou, M.,Narita, T.,Yamada, T.,Yamaguchi, Y.,Wada, T.,Handa, H.","A rapid purification method for human RNA polymerase II by two-step affinity chromatography",,"J. Biochem.",,"Vol. 133",,"pp. 133-138",2003,Jan.
"Nedialkov, Y.A.,Gong, X.Q.,Yamaguchi, Y.,Handa, H.,Burton, Z.F.","Assay of transient state kinetics of elongation by human RNA polymerase II",,"Methods in Enzymol.",,"Vol. 371",,"pp. 252-264",2003,
"山口雄輝","わかる実験医学シリーズ 転写がわかる",,"羊土社","羊土社",,,,2002,
"Yamaguchi, Y.,Delehouzee, S.,Handa, H.","HIV and HDV: evolution takes different paths to relieve blocks in transcriptional elongation",,"Microbes Infect.",,"Vol. 4",,"pp. 1169-1175",2002,
"Nishi, T.,Shimizu, N.,Hiramoto, M.,Sato, I.,Yamaguchi, Y.,Hasegawa, M.,Aizawa, S.,Tanaka, H.,Kataoka, K.,Watanabe, H.,Handa, H.","Spatial redox regulation of a critical cysteine residue of NF-kB in vivo",,"J. Biol. Chem.",,"Vol. 277",,"pp. 44548-44556",2002,
"Yamaguchi, Y.,Inukai, N.,Narita, T.,Wada, T.,Handa, H.","Evidence that negative elongation factor represses transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II complex and RNA",,"Mol. Cell. Biol.",,"Vol. 22",,"pp. 2918-2927",2002,
"Yamaguchi, Y.,Narita, T.,Inukai, N.,Wada, T.,Handa, H.","SPT genes: Key players in the regulation of transcription, chromatin structure and other cellular processes",,"J. Biochem.",,"Vol. 129",,"pp. 185-191",2001,
"Yamaguchi, Y.,Filipovska, J.,Yano, K.,Furuya, A.,Inukai, N.,Narita, T.,Wada, T.,Sugimoto, S.,Konarska, M.M.,Handa, H.","Stimulation of RNA polymerase II elongation by hepatitis delta antigen",,"Science",,"Vol. 293",,"pp. 124-127",2001,
"Renner, D.B.,Yamaguchi, Y.,Wada, T.,Handa, H.,Price, D.H.","A highly purified RNA polymerase II elongation control system",,"J. Biol. Chem",,"Vol. 276",,"pp. 42601-42609",2001,
"Kim, D.,Yamaguchi Y.,Wada, T.,Handa, H.","The regulation of elongation by eukaryotic RNA polymerase II: A recent view.",,"Mol. Cells",,"Vol. 11",,"pp. 267-274",2001,
"Shiba, K.,Hamaguchi, T.,Kataoka, K.,Yamaguchi, Y.,Handa, H.,Adachi, K.","Cloning of the hamstar androgen receptor gene",,"J. Dermatol. Sci.",,"Vol. 26",,"pp. 163-168",2001,
"Wada, T.,Orphanides, G.,Hasegawa, J.,Kim,D.-K.,Shima, D.,Yamaguchi, Y.,Fukuda, A.,Hisatake, K.,Oh, S.,Reinberg, D.,Handa, H.","FACT relieves DSIF/NELF-mediated inhibition of transcriptional elongation and reveals functional differences between P-TEFb and TFIIH",,"Mol. Cell",,"Vol. 5",,"pp. 1067-1072",2000,
"山口雄輝","ゲノムからの情報発現 転写因子とその機能",,"シュプリンガー・フェアラーク","シュプリンガー・フェアラーク",,,,2000,
"Guo, S.,Yamaguchi, Y.,Schilbach, S.,Wada, T.,Lee, J.,Goddard, A.,French, D.,Handa, H.,Rosenthal, A.","A regulator of transcriptional elongation controls vertebrate neuronal development",,"Nature",,"Vol. 408",,"pp. 366-369",2000,
"山口雄輝","BioScience用語ライブラリー新版",,,,,,,1999,Sept.
"山口雄輝","転写伸長反応を抑制する因子群の同定と解析",,,,,,,1999,Mar.
"山口雄輝","転写伸長反応を抑制する因子群の同定と解析",,,,,,,1999,Mar.
"Azuma, N.,Yamaguchi, Y.,Handa, H.,Hayakawa, M.,Kanai, A.,Yamada, M.","Missense mutation in the alternative splice region of the PAX6 gene in eye anomalies.",,"Am. J. Hum. Genet.",,"Vol. 65",,"pp. 656-663",1999,
"Kim, J.B.,Yamaguchi, Y.,Wada, T.,Handa, H.,Sharp, P.A.","Tat-SF1 protein associates with RAP30 and human SPT5 proteins",,"Mol. Cell. Biol.",,"Vol. 19",,"pp. 5960-5968",1999,
"Yamaguchi, Y.,Wada, T.,Watanabe, D.,Takagi, T.,Hasegawa, J.,Handa, H.","Structure and function of the human transcription elongation factor DSIF.",,"J. Biol. Chem.",,"Vol. 274",,"pp. 8085-8092",1999,
"Yamaguchi, Y.,Takagi, T.,Wada, T.,Yano, K.,Furuya, A.,Sugimoto, S.,Hasegawa, J.,Handa, H.","NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation",,"Cell",,"Vol. 97",,"pp. 41-51",1999,
"Handa, H.,Yamaguchi, Y.,Wada, T.","Purification of DNA binding proteins. in High resolution chromatography: A practical approach",,"Oxford University Press","Oxford University Press",,,"pp. 283-302",1999,
"Yamaguchi, Y.,Wada, T.,Suzuki, F.,Takagi, T.,Hasegawa, J.,Handa, H.","Casein kinase II interacts with the bZIP domains of several transcription factors",,"Nucleic Acids Res.",,"Vol. 26",,"pp. 3854-3861",1998,
"Wada, T.,Takagi, T.,Yamaguchi, Y.,Ferdous, A.,Imai, T.,Hirose, S.,Sugimoto, S.,Yano, K.,Hartzog, G.A.,Winston, F.,Buratowski, S.,Handa, H.","DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs.",,"Genes Dev.",,"Vol. 12",,"pp. 343-356",1998,
"Yamaguchi, Y.,Wada, T.,Handa, H.","Interplay between positive and negative elongation factors: drawing a new view of DRB",,"Genes Cells",,"Vol. 3",,"pp. 9-15",1998,
"Wada, T.,Takagi, T.,Yamaguchi, Y.,Watanabe, D.,Handa, H.","Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro",,"EMBO J.",,"Vol. 17",,"pp. 7395-7403",1998,
"Yamaguchi, Y.,Sawada, J.,Yamada, M.,Handa, H.,Azuma, N.","Autoregulation of Pax6 transcriptional activation by two distinct DNA-binding subdomains of the paired domain",,"Genes Cells",,"Vol. 2",,"pp. 255-261",1997,
"Wada, T.,Takagi, T.,Yamaguchi, Y.,Kawase, H.,Hiramoto, M.,Ferdous, A.,Takamiya, M.,Lee, K.A.,Hurst, H.C.,Handa, H.","Copurification of casein kinase II with transcription factor ATF/E4TF3",,"Nucleic Acids Res.",,"Vol. 24",,"pp. 876-884",1996,
"山口雄輝","BioScience用語ライブラリー",,,"羊土社",,,,1995,Sept.