"Kimura A.,Kitajima, M.,Nishida, K.,Serada, S.,Fujimoto, M.,Naka, T.,Fujii-Kuriyama, Y.,Satoshi Sakamoto,Takumi Ito,HIROSHI HANDA,Tanaka, T.,Yoshimura, A,Suzuki, H.","NQO1 inhibits TLR-dependent production of selective cytokines by promoting PDLIM2-mediated degradation of IkB-z",,"J. Exp. Med.",,"Vol. 215","No. 8","p. 2197-2209",2018,June "Tomoyuki Mori,Takumi Ito,Shujie Liu,Hideki Ando,Satoshi Sakamoto,Yuki Yamaguchi,Etsuko Tokunaga,Norio Shibata,Hiroshi Handa","Structural basis of thalidomide enantiomer binding to cereblon",,"Scientific Reports",," 8"," 1"," 1294",2018,Jan. "ˆÉ“¡ ‘ñ…,’©È ’mŽq,ŽR–{ ~ˆê,ˆÀ“¡ GŽ÷,²“¡ ’q”ü,ŽRŒû —Y‹P,”¼“c G","ƒŠƒKƒ“ƒhˆË‘¶“Iƒ†ƒrƒLƒ`ƒ“ƒŠƒK[ƒ[‚b‚q‚a‚m‚̧Œä‹@\","“ú–{ƒPƒ~ƒJƒ‹ƒoƒCƒIƒƒW[Šw‰ï‘æ11‰ñ”N‰ï",,,,,,2016,June "â–{ ‘,ˆÉ“¡ ‘ñ…,X ’qs,ˆÀ“¡ GŽ÷,ŽRŒû —Y‹P,” “ˆ •q—Y,”¼“c G","CRBN‚ɑ΂·‚éƒTƒŠƒhƒ}ƒCƒhŒõŠwˆÙ«‘Ì‚ÌŒ‹‡Šî”Õ‰ðÍ","“ú–{ƒPƒ~ƒJƒ‹ƒoƒCƒIƒƒW[Šw‰ï‘æ11‰ñ”N‰ï",,,,,,2016,June "Satoshi Sakamoto,Yuki Yamaguchi,Takumi Ito,Hiroshi Handa","Elucidation of the molecular mechanisms of action of bioactive natural products using high performance affinity beads","PACIFCHEM2015",,,,,,2015,Dec. "Satoshi Sakamoto,Takumi Ito,Yuki Yamaguchi,Hideki Ando,Hiroshi Handa","Biochemical analyses of CRBN, the target protein for immunomodulatory drugs (IMiDs)","PACIFCHEM2015",,,,,,2015,Dec. "â–{ ‘,ˆÉ“¡ ‘ñ…,ˆÀ“¡ GŽ÷,ŽRŒû —Y‹P,”¼“c G","IMiDs•W“Iƒ^ƒ“ƒpƒNŽ¿CRBN‚̶‰»Šw“I‰ðÍ","“ú–{ƒPƒ~ƒJƒ‹ƒoƒCƒIƒƒW[Šw‰ï‘æ‚P‚O‰ñ”N‰ï",,,,,,2015,June "ät‘¢ ³‰p,ˆÉ“¡ ‘ñ…,ˆÀ“¡ GŽ÷,ŽRŒû —Y‹P,”¼“c G","‘½”­«œ‘Žî‚É‚¨‚¯‚éCRBN Œ‹‡ˆöŽq‚Ì’Tõ‹y‚щðÍ","‘æ‚R‚U‰ñ“ú–{•ªŽq¶•¨Šw‰ï”N‰ï",,,,,,2013,Dec. "”Ñ“c Œ‹,ˆÉ“¡ ‘ñ…,ˆÀ“¡ GŽ÷,ŽRŒû —Y‹P,”¼“c G","ƒTƒŠƒhƒ}ƒCƒhƒ^[ƒQƒbƒg•ªŽqCRBN ‚̶‰»Šw“I‰ðÍ","‘æ‚R‚U‰ñ“ú–{•ªŽq¶•¨Šw‰ï”N‰ï",,,,,,2013,Dec. "Kentaro Hotta,Akihiro Nashimoto,Eiji Yasumura,Masafumi Suzuki,Motoki Azuma,Yosuke Iizumi,Daisuke Shima,Ryusuke Nabeshima,Masaki Hiramoto,Akira Okada,Kumiko Sakata-Sogawa,Makio Tokunaga,Takumi Ito,Hideki Ando,Satoshi Sakamoto,Yasuaki Kabe,Shinichi Aizawa,Takeshi Imai,Yuki Yamaguchi,Hajime Watanabe,Hiroshi Handa","Vesnarinone suppresses TNFƒ¿ mRNA expression by inhibiting valosin-containing protein",,"Mol. Pharmacol.",,"Vol. 83","No. 5","pp. 930-938",2013,May "Yuki Ito,Takumi Ito,Satoki Karasawa,Teruya Enomoto,Nashimoto, Akihiro,Hase, Yasuyoshi,Sakamoto, Satoshi,Mimori, Tsuneyo,Yoshihisa Matsumoto,Yuki Yamaguchi,HIROSHI HANDA","Identification of DNA-Dependent Protein Kinase Catalytic Subunit (DNA-PKcs) as a Novel Target of Bisphenol A",,"Plos One",,"Vol. 7","No. 12","p. e50481",2012,Dec. "HIROSHI HANDA,Takumi Ito","Deciphering the mystery of thalidomide teratogenicity",,"Congenital Anomalies",,"Vol. 52","No. 1","pp. 1-7",2012,Mar. "Satoshi Sakamoto,Mamoru Hatakeyama,Takumi Ito,Hiroshi Handa","Tools and methodologies capable of isolating and identifying a target molecule for a bioactive compound",,"Bioorganic & Medicinal Chemistry",,"Vol. 20","No. 6","pp. 1990?2001",2012,Mar. "Naoya Maekawa,Masaki Hiramoto,Satoshi Sakamoto,Motoki Azuma,Takumi Ito,Marie Ikeda,Michitaka Naitou,Hukum P. Acharya,Yuichi Kobayashi,Makoto Suematsu,Hiroshi Handa,Takeshi Imai","High-performance affinity purification for identification of 15-deoxy-ƒ¢12,14-PGJ2 interacting factors using magnetic nanobeads",,"Biomedical Chromatography",,"Vol. 25","No. 4","pp. 466?471",2011,Apr. "Miho Aizawa,Yuichi Abe,Takumi Ito,Hiroshi Handa,Hiroyuki Nawa","mRNA distribution of the thalidomide binding protein cereblon in adult mouse brain",,"Neuroscience Research",,"Vol. 69","No. 4","pp. 343?347",2011,Apr. "Takumi Ito,Hideki Ando,Hiroshi Handa","Teratogenic effects of thalidomide: molecular mechanisms",,"Cellular and Molecular Life Sciences",,"Vol. 68","No. 9","pp. 1569-1579",2011,Mar. "Takumi Ito,Hideki Ando,Takayuki Suzuki,Toshihiko Ogura,Kentaro Hotta,Yoshimasa Imamura,Yuki Yamaguchi,Hiroshi Handa","Identification of a primary target of thalidomide teratogenicity",,"Science",,"Vol. 327","No. 5971","p. 1345-1350",2010,Mar.