"オンゴノ スワンディ,近藤科江,門之園 哲哉","抗原密度依存的に結合するタンデム三量体Nanobodyの創出とADCC活性評価","第28回日本がん分子標的治療学会学術集会",,,,,,2024,June "上條航生,宮本康太郎,近藤科江,門之園 哲哉","RNA-seq遺伝子発現解析による休眠がん細胞マーカーの探索","第28回日本がん分子標的治療学会学術集会",,,,,,2024,June "門之園 哲哉","抗原親和性エンジニアリングによる次世代バイオ医薬品デザイン","第33回日本がん転移学会学術集会『癌創薬研究の未来予想図』",,,,,,2024,June "門之園 哲哉","スマートデザインによる抗体模倣中分子ペプチドの創出","第67回日本腎臓学会学術総会『新規創薬モダリティが切り開く腎臓病治療の未来』",,,,,,2024,June "松本真愛,近藤科江,門之園 哲哉","抗原親和性の異なるCAR-T細胞の活性化および疲弊マーカー発現パターン解析","第28回日本がん分子標的治療学会学術集会",,,,,,2024,June "長谷川佳保,門之園 哲哉,近藤科江","細胞障害性の高い細胞を腫瘍へ誘導する二重特異性抗体の創製","第28回日本がん分子標的治療学会学術集会",,,,,,2024,June "Ning Lin,Kotaro Miyamoto,Takumi Ogawara,Saki Sakurai,Shinae Kizaka-Kondoh,Tetsuya Kadonosono","Epitope binning for multiple antibodies simultaneously using mammalian cell display and DNA sequencing",,"Communications Biology",,"Vol. 7",,"pp. 652",2024,May "Maho Kaminaga,Shuta Otomo,Seisyu Tsunozaki,Tetsuya Kadonosono,Toru Omata","Fabrication of a Cancer Cell Aggregate Culture Device That Facilitates Observations of Nutrient and Oxygen Gradients",,"Micromachines (Basel)",,"Vol. 15","No. 6","pp. 689",2024,May "上條航生,宮本康太郎,近藤科江,門之園 哲哉","遺伝子発現解析による休眠がん細胞のバイオマーカー探索","量子生命科学会第6回大会",,,,,,2024,May "門之園 哲哉","哺乳類細胞ディスプレイを利用する高性能抗原結合分子の創出と評価","CPHI Japan 2024 バイオファーマセミナー",,,,,,2024,Apr. "門之園 哲哉","哺乳類細胞分子ディスプレイによる高性能バイオ医薬デザイン","日本薬学会第144年会『境界を超える融合研究:次世代が切り拓く創薬モダリティと分子計測』",,,,,,2024,Mar. "John Clyde CoSoriano,Shiho Tsutsumi,Daiya Ohara,Keiji Hirota,Gen Kondoh,Tatsuya Niwa,Hideki Taguchi,Tetsuya Kadonosono*,Shinae Kizaka-Kondoh","Identification of surface markers and functional characterization of myeloid derived suppressor cell-like adherent cells",,"Adv Biol (Weinh)",,"Vol. 8","No. 3","pp. e2300159",2024,Mar. "Tetsuya Kadonosono","Smart design system for developing high-performance biologics","RWTH Aachen University-TokyoTech-Tokyo Medical and Dental University Joint Workshop",,,,,,2024,Feb. "M. Minegishi,T. Kuchimaru,K. Nishikawa,T. Isagawa,S. Iwano,K. Iida,H. Hara,S. Miura,M. Sato,S. Watanabe,A. Shiomi,Y. Mabuchi,H. Hamana,H. Kishi,T. Sato,D. Sawaki,S. Sato,Y. Hanazono,A. Suzuki,T. Kohro,T. Kadonosono,T. Shimogori,A. Miyawaki,N. Takeda,H. Shintaku,S. Kizaka-Kondoh,S. Nishimura","Secretory GFP reconstitution labeling of neighboring cells interrogates cell?cell interactions in metastatic niches",,"Nature Communications",,"Vol. 14","No. 1","pp. 8031",2023,Dec. "Suwandi Onggono,門之園 哲哉","Development and binding-mode analysis of tandem trimeric nanobody to bind specifically on antigen-overexpressing cells","第46回 日本分子生物学会年会",,,,,,2023,Dec. "Takumi Ogawara,Ning Lin,Tetsuya Kadonosono","Development of binding affinity scoring system for mammalian cell-surface displayed antibody library","第46回 日本分子生物学会年会",,,,,,2023,Dec. "星慶吾,Lin Ning,門之園哲哉","生理活性ペプチドKp10の細胞表層ディスプレイと細胞増殖促進効果の解析","第46回 日本分子生物学会年会",,,,,,2023,Dec. "Yuki Sakamoto,Mahiro Matsumoto,Tetsuya Kadonosono","抗原親和性の異なるHER2標的CAR-T細胞の活性化レベルおよび疲弊レベル解析","第46回 日本分子生物学会年会",,,,,,2023,Dec. "門之園 哲哉","T細胞のがん攻撃スイッチ",,"生物工学会誌",,"Vol. 101","No. 12","pp. 641",2023,Dec. "山川 萌恵,小川原 巧,坂本 祐基,Lin Ning,門之園 哲哉","ナノ膜小胞による膜タンパク質標的抗体の結合親和性評価法の開発","第46回 日本分子生物学会年会",,,,,,2023,Dec. "Yuki Sakamoto,Mahiro Matsumoto,Tetsuya Kadonosono","抗原結合残基の置換によるHER2標的Nanobody型CAR-T細胞の親和性最適化","第40回メディシナルケミストリーシンポジウム",,,,,,2023,Nov. "Ning Lin,Kotaro Miyamoto,Takumi Ogawara,Tetsuya Kadonosono","A Monoclonal Antibody-guided Screening Platform for the Efficient Identification of Epitope-specific Antibodies","第40回メディシナルケミストリーシンポジウム",,,,,,2023,Nov. "Keigo Hoshi,Takumi Ogawara,Lin Ning,Tetsuya Kadonosono","Evaluation of kisspeptin-10 activity using a mammalian cell-surface display system","第60回ペプチド討論会",,,,,,2023,Nov. "Takumi Ogawara,Lin Ning,Tetsuya Kadonosono","Development of affinity scoring system for mammalian cell-displayed antibody library","第60回ペプチド討論会",,,,,,2023,Nov. "Suwandi Onggono,Tetsuya Kadonosono","Development of nanobody for specific binding on antigen-high-expressing cells by affinity optimization and tandem trimerization","第60回ペプチド討論会",,,,,,2023,Nov. "門之園 哲哉","細胞ディスプレイを基軸とするバイオ医薬デザインシステムの開拓","2023生命創薬ギルド",,,,,,2023,Oct. "小川原 巧,門之園 哲哉","抗体誘導スクリーニング法による抗体代替ナノボディの同定","第75回日本生物工学会",,,,,,2023,Sept. "Ning Lin,Tetsuya Kadonosono","Development of Evaluation System for Antibody Epitopes by Co-display of Antibodies and Antigen on Mammalian Cells","第75回日本生物工学会",,,,,,2023,Sept. "Onggono Suwandi,門之園 哲哉","親和性最適化による標的細胞特異的な直列三量体ナノボディの創出","第75回日本生物工学会",,,,,,2023,Sept. "坂本 祐基,門之園 哲哉","CAR-T 細胞の活性化および疲弊レベル解析による抗原親和性最適化技術の開発","第75回日本生物工学会",,,,,,2023,Sept. "星 慶吾,Lin Ning,門之園 哲哉","細胞表層にディスプレイしたKp10ペプチドの細胞増殖促進効果の解析","第55回若手ペプチド夏の勉強会",,,,,,2023,Aug. "Onggono Suwandi,門之園 哲哉","親和性最適化による抗原過剰発現細胞に特異的な直列三量体ナノボディの創出","第55回若手ペプチド夏の勉強会",,,,,,2023,Aug. "小川原 巧,Lin Ning,門之園 哲哉","細胞ディスプレイによるHER2結合分子ライブラリーの親和性一括スコア化","第55回若手ペプチド夏の勉強会",,,,,,2023,Aug. "山川 萌恵,小川原 巧,坂本 祐基,Lin Ning,門之園 哲哉","ナノ膜小胞MNVによる膜タンパク質標的抗体の親和性評価法の構築","第55回若手ペプチド夏の勉強会",,,,,,2023,Aug. "上條 航生,宮本 康太郎,門之園 哲哉","休眠がん細胞を検出するためのバイオマーカーの探索","第55回若手ペプチド夏の勉強会",,,,,,2023,Aug. "H. Miyabara,R. Hirano,S. Watanabe,J.C. CoSoriano,H. Watanabe,T. Kuchimaru,N. Kitada,T. Kadonosono,S.A. Maki,G. Kondoh,S. Kizaka-Kondoh","In vivo optical imaging of tumor stromal cells with hypoxia-inducible factor activity",,"Cancer Science",,"Vol. 114","No. 10","pp. 3935-3945",2023,July "門之園 哲哉","中分子ペプチド医薬の開発戦略と臨床応用への展望","ATAGO Respiratory Expert Seminar",,,,,,2023,July "Tetsuya Kadonosono","Engineering of antibody-mimetic HER2-binding small proteins by Smart Design technology","2023 Annual Spring Meeting of the Korean BioChip Society",,,,,,2023,June "オンゴノ スワンディ,近藤 科江,門之園 哲哉","抗原過剰発現細胞に特異的に結合する直列三量体ナノボディの創出","第27回日本がん分子標的治療学会学術集会",,,,,,2023,June "小川原 巧,近藤 科江,門之園 哲哉","抗体誘導スクリーニング技術による抗体代替ナノボディの探索","第27回日本がん分子標的治療学会学術集会",,,,,,2023,June "坂本 祐基,近藤 科江,門之園 哲哉","抗原親和性の異なるナノボディ型CAR-T細胞の活性化および疲弊レベル解析","第27回日本がん分子標的治療学会学術集会",,,,,,2023,June "門之園 哲哉,近藤 科江","腫瘍内HIF活性化細胞を検出するナノ量子センサーの開発","量子生命科学会 第5回大会",,,,,,2023,May "Yuichi Kida,Toshiki Sawada,Tomio Iwasaki,Tetsuya Kadonosono,Takeshi Serizawa","Identification of peptides as a molecular glue for polytetrafluoroethylene",,"Polymer journal",,"Vol. 55",,,2023,Apr. "門之園哲哉,齋藤裕,Lin Ning,近藤科江","スマートデザインによる抗体代替HER2結合小型タンパク質の創出","日本薬学会第143年会",,,,,,2023,Mar. "R. Hirano,K. Okamoto,M. Shinke,M. Sato,S. Watanabe,H. Watanabe,G. Kondoh,T. Kadonosono,S. Kizaka-Kondoh","Tissue-resident macrophages are major tumor-associated macrophage resources, contributing to early TNBC development, recurrence, and metastases",,"Communications Biology",,"Vol. 6",,"pp. 144",2023,Feb. "Ning Lin,Saki Sakurai,Shinae Kizaka-Kondoh,Tetsuya Kadonosono","Development of an antibody-guided screening system for identifying epitope-directed anti-HER2 antibody mimetics","第45回日本分子生物学会年会",,,,,,2022,Dec. "Fahsai Nakarin,Shinae Kizaka-Kondoh,Tetsuya Kadonosono","Development of a design system for T-cell receptor mimic antibodies targeting cancer neoantigens","第45回日本分子生物学会年会",,,,,,2022,Dec. "門之園 哲哉","抗体医薬代替分子のスマートデザインによる小型タンパク質創薬","第14回ABC-InFO講演会",,,,,,2022,Dec. "門之園 哲哉","シン・中分子ペプチド創薬への技術革新と進化",,"実験医学","羊土社","Vol. 41","No. 1",,2022,Dec. "John Clyde Co Soriano,Daiya Ohara,Keiji Hirota,Gen Kondoh,Tatsuya Niwa,Tetsuya Kadonosono,Shinae Kizaka-Kondoh","Identification of Surface Markers and Functional activities of MDSC-like Adherent Cells (MLAC)","第45回日本分子生物学会年会",,,,,,2022,Dec. "NG SIN YING,高野 恵理子,Alex Nguyen,近藤 科江,門之園 哲哉","結合親和性の異なるCD25標的CAR-T細胞の活性化と疲弊レベルの評価","SJWS第14回学術大会",,,,,,2022,Dec. "Ng Sin Ying,Eriko Takano,Alex Nguyen,Shinae Kizaka-Kondoh,Tetsuya Kadonosono","Evaluation of activation and exhaustion levels of CD25-targeting CAR-T cells with different binding affinities","第45回日本分子生物学会年会",,,,,,2022,Dec. "武藤昌也,?一誠,平山明由,北島正二郎,曽我朋義,門之園哲哉,近藤科江","腫瘍内ネクローシス領域が関与する悪性化機構の解明","第18回がんとハイポキシア研究会",,,,,,2022,Nov. "角崎青周,大友秀太,門之園哲哉,小俣透","低酸素低栄養領域の観察とアクセスが容易ながん細胞培養デバイス","化学とマイクロ・ナノシステム学会第46回研究会",,,,,,2022,Nov. "菊本要,門之園哲哉,小俣透","がん細胞スフェロイドを対象としたエンドサイトーシス抑制ファージディスプレイスクリーニングマイクロ流体デバ イス","化学とマイクロ・ナノシステム学会第46回研究会",,,,,,2022,Nov. "平野龍一郎,岡本浩輝,渡邊仁美,近藤玄,門之園哲哉,近藤科江","乳腺組織常在性マクロファージ阻害はトリプルネガティブ乳がん再発を抑制する","第18回がんとハイポキシア研究会",,,,,,2022,Nov. "櫻井咲季,Lin Ning,門之園哲哉,近藤科江","細胞表層ディスプレイによるHER2 結合分子群の親和性一括評価","第18回がんとハイポキシア研究会",,,,,,2022,Nov. "高野 恵理子,Ng Sin Ying,Alex Nguyen,門之園 哲哉,近藤 科江","CD25 標的CAR-T 細胞の活性化および疲弊状態評価システムの開発","第18回がんとハイポキシア研究会",,,,,,2022,Nov. "?一誠,武藤昌也,平山明由,北島正二郎,曽我朋義,門之園哲哉,近藤科江","腫瘍内ネクローシス領域の成分によるマクロファージ極性化作用の検証","第18回がんとハイポキシア研究会",,,,,,2022,Nov. "岡本浩輝,平野龍一郎,門之園哲哉,近藤科江","乳腺組織常在性間質細胞によるTNBC 増殖促進作用","第18回がんとハイポキシア研究会",,,,,,2022,Nov. "K Okamoto,Masaya Muto,Tetsuya Kadonosono,Kiichi Kaminaga,Ryuji Igarashi,Shinae Kizaka-Kondoh","Evaluation of the surface-modified nanodiamond probes by in vivo fluorescence imaging","The 5th International Forum on Quantum Metrology and Sensing",,,,,,2022,Nov. "Saki Sakurai,Lin Ning,Shinae Kizaka-Kondoh,Tetsuya Kadonosono","DEVELOPMENT OF AFFINITY EVALUATION SYSTEM FOR CELL-SURFACE DISPLAYED ANTIBODIES","第59回ペプチド討論会",,,,,,2022,Oct. "岡本 浩輝,平野 龍一郎,門之園 哲哉,近藤 科江","乳腺組織常在性間質細胞による TNBC 増殖促進作用","第81回日本癌学会学術集会",,,,,,2022,Oct. "平野 龍一郎,岡本 浩輝,門之園 哲哉,近藤 科江","乳腺組織常在性マクロファージ阻害はトリプルネガティブ乳がん再発を抑制する","第81回日本癌学会学術集会",,,,,,2022,Oct. "Takumi Ogawara,Shinae Kizaka-Kondoh,Tetsuya Kadonosono","ANTIBODY-GUIDED IDENTIFICATION OF ANTIBODY MIMETIC NANOBODIES","第59回ペプチド討論会",,,,,,2022,Oct. "Eriko Takano,Ng Sin Ying,Alex Nguyen,Shinae Kizaka-Kondoh,Tetsuya Kadonosono","Development of evaluation system for activation and exhaustion levels of CD25-targeting CAR-T cells","第59回ペプチド討論会",,,,,,2022,Oct. "武藤 昌也,シェ 一誠,平山 明由,北島 正二朗,曽我 朋義,門之園 哲哉,近藤 科江","腫瘍内ネクローシス領域を介した悪性化機構におけるマクロファージの関与の解明","第81回日本癌学会学術集会",,,,,,2022,Sept. "Sin Ying Ng,Eriko Takano,Shinae Kizaka-Kondoh,Tetsuya Kadonosono","Development of evaluation system for the activity of CD25-targeting CAR-T cells","2022 International Young Woman Scientist Camp",,,,,,2022,Aug. "小川原 巧,Lin Ning,近藤 科江,門之園 哲哉","抗体誘導スクリーニングシステムによるPertuzumab代替Nanobodyの探索","第54回若手ペプチド夏の勉強会",,,,,,2022,Aug. "Tetsuya Kadonosono,Shinae Kizaka-Kondoh","Development of CD25-targeting antibody mimetics by antibody-guided library design and screening","European Peptide Symposium 2022",,,,,,2022,Aug. "T. Kadonosono,K. Miyamoto,S. Sakai,Y. Matsuo,S. Kitajima,Q. Wang,M. Endo,M. Niibori,T. Kuchimaru,T. Soga,K. Hirota,S. Kizaka-Kondoh","AGE/RAGE axis regulates reversible transition to quiescent states of ALK-rearranged NSCLC and pancreatic cancer cells in monolayer cultures",,"Sci. Rep.",,"Vol. 12","No. 1","pp. 9886",2022,June "Tetsuya Kadonosono,Shinae Kizaka-Kondoh","Display and selection of peptide library on mammalian cell surface for developing CD25-binding antibody mimetics","Antibody Engineering and Therapeutics Europe 2022",,,,,,2022,June "門之園 哲哉","中分子ペプチド創薬の新展開-抗体代替ペプチドのデザイン戦略",,"化学と生物",,"Vol. 60","No. 6","pp. 284?289",2022,June "門之園 哲哉,岡本 浩輝,武藤 昌也,神長 輝一,五十嵐 龍治,近藤 科江","In vivo蛍光イメージングによる表面修飾ナノダイヤモンドプローブの残留性評価","量子生命科学会 第4回大会",,,,,,2022,May "Tsuyohi Sato,Akira Hamai,Tetsuya Kadonosono,Shinae Kizaka-Kondoh,Toru Omata","Droplet-based valveless microfluidic system for phage-display screening against spheroids",,"Biomicrofluidics","AIP Publishing","Volume 16","Issue 2",,2022,Apr. "稲葉千尋,澤田敏樹,門之園哲哉,芹澤武","高分子結合性ペプチドの細胞表層ディスプレイとその温度依存的な親和性評価","日本化学会第102春季年会",,,,,,2022,Mar. "Tetsuya Kadonosono","MAGPIE system for efficient development of small antibody mimetics","10th Tokyo Tech International Symposium on Life Science and Technology "Biomolecular Evolution and Engineering"",,,,,,2022,Jan. "Tetsuya Kadonosono,Wanaporn Yimchuen,Kyra See,Shinae Kizaka-Kondoh","Strategic design to create clinically applicable HER2-targeting small proteins with immobilized target-binding peptides","Pacifichem 2021",,,,,,2021,Dec. "武藤 昌也,平山 明由,北島 正二郎,曽我 朋義,門之園 哲哉,近藤 科江","腫瘍内ネクローシス領域が関与する悪性化亢進メカニズムの解明","第44回日本分子生物学会年会",,,,,,2021,Dec. "Misa Minegishi,Tetsuya Kadonosono,Shinae Kizaka-Kondoh,Takahiro Kuchimaru","Novel technology for fluorescent protein labeling of stromal cells in close proximity to cancer cells in living tissues","Pacifichem 2021",,,,,,2021,Dec. "Tetsuya Kadonosono,Shinae Kizaka-Kondoh","Development of CD25-binding antibody mimetics by antibody-guided library design and screening","Antibody Engineering and Therapeutics US 2021",,,,,,2021,Dec. "新毛 実結,平野 龍一郎,門之園 哲哉,渡邊 仁美,近藤 玄,近藤 科江","トリプルネガティブ乳がんの血管新生および局所再発における乳腺組織常在性細胞の関与","第44回日本分子生物学会年会",,,,,,2021,Dec. "岡本 浩輝,平野 龍一郎,門之園 哲哉,渡邊 仁美,近藤 玄,近藤 科江","乳腺組織常在性間質細胞によるTNBC増殖促進作用","第44回日本分子生物学会年会",,,,,,2021,Dec. "K. See,T. Kadonosono,K. Miyamoto,T. Tsubaki,Y. Ota,M. Katsumi,S. Ryo,K. Aida,M. Minegishi,T. Isozaki,T. Kuchimaru,S. Kizaka-Kondoh","Antibody-guided design and identification of CD25-binding small antibody mimetics using mammalian cell surface display",,"Sci. Rep.",,"Vol. 11","No. 1","pp. 22098",2021,Nov. "門之園 哲哉","スマートデザインによるT細胞増殖促進ペプチドの創製","第94回日本生化学会大会シンポジウム『生理活性ペプチドと中分子創薬〜新たな創薬ブレイクスルーを目指して』",,,,,,2021,Nov. "Y. Matsuzaki,W. Aoki,T. Miyazaki,S. Aburaya,Y. Ohtani,K. Kajiwara,N. Koike,H. Minakuchi,N. Miura,T. Kadonosono,M. Ueda","Peptide barcoding for one-pot evaluation of sequence-function relationships of nanobodies",,"Sci. Rep.",,"Vol. 11","No. 1","pp. 21516",2021,Nov. "稲葉千尋,澤田敏樹,門之園哲哉,芹澤武","Polymer-binding peptide as a molecular tool for cell imaging","第58回ペプチド討論会",,,,,,2021,Oct. "宮本 康太郎,門之園 哲哉,北島 正二朗,曽我 朋義,近藤 科江","誘導性休眠がん細胞の低酸素低血清条件下でのトランスクリプトームおよびメタボローム解析","第80回日本癌学会学術集会",,,,,,2021,Oct. "平野 龍一郎,岡本 浩輝,新毛 実結,門之園 哲哉,近藤 科江","組織常在性細胞はトリプルネガティブ乳がんの増殖を促進する","第80回日本癌学会学術集会",,,,,,2021,Oct. "門之園 哲哉","スマートデザインによるCD25結合抗体代替ペプチドの創製","第15回次世代を担う若手のための医療薬科学シンポジウム",,,,,,2021,Oct. "Misa Minegishi,Tetsuya Kadonosono,Shinae Kizaka-Kondoh,Takahiro Kuchimaru","A Fluorescent labeling system of proximal cells for single-cell omics analysis of cellular interactions in metastasis","第80回日本癌学会学術集会シンポジウム『光が拓く次世代イメージングツール』",,,,,,2021,Oct. "Shinae Kizaka-Kondoh,Hitomi Miyabara,Ryuichiro Hirano,Tetsuya Kadonosono,Takahiro Kuchimaru","Identification and elucidation of therapeutic targets by in vivo optical imaging","第80回日本癌学会学術集会シンポジウム『転移:多面的な理解による新しい治療戦略の展開』",,,,,,2021,Sept. "武藤 昌也,平山 明由,北島 正二朗,曽我 朋義,門之園 哲哉,近藤 科江","腫瘍内ネクローシス領域が関与する悪性化機構の解明","第80回日本癌学会学術集会",,,,,,2021,Sept. "茂呂健太,滝澤実咲,澤田敏樹,門之園哲哉,芹澤武","ペプチドの親和性に基づく機能性分子と医用高分子との効率的な複合化","第70回高分子討論会",,,,,,2021,Sept. "門之園 哲哉","抗体代替ペプチドのスマートデザインと革新的モダリティ創発","新化学技術推進協会ライフサイエンス技術部会材料科会勉強会『第4回AI・MI勉強会』",,,,,,2021,Sept. "本間滉也,門之園哲哉,佐藤伸一,近藤科江","KISS1R発現がん細胞を検出する生物発光イメージングプローブの創製","第53回若手ペプチド夏の勉強会",,,,,,2021,Aug. "門之園 哲哉","スマートデザインによる高性能標的結合中分子の創製",,"日本農薬学会誌",,"Vol. 46","No. 2","pp. 1-5",2021,Aug. "宮本康太郎,門之園哲哉,長谷川拓哉,近藤科江","担がんマウスにおけるアルブミン結合ドメイン融合ナノボディの動態評価","第53回若手ペプチド夏の勉強会",,,,,,2021,Aug. "Kyra See,門之園哲哉,宮本康太郎,近藤科江","抗体誘導スクリーニングによるCD25結合抗体代替ペプチドの開発","第53回若手ペプチド夏の勉強会",,,,,,2021,Aug. "峯岸美紗,門之園 哲哉,近藤 科江,口丸 高弘","転移過程のがん-間質細胞相互作用の一細胞オミクス解析技術の開発","第30回日本がん転移学会学術集会総会",,,,,,2021,July "Masayoshi Tanaka,Mirei Hayashi,Roach Lucien,Yuka Kiriki,Tetsuya Kadonosono,Takahiro Nomoto,Nobuhiro Nishiyama,Choi Jonghoon,Critchley Kevin,D. Evans Stephen,Mina Okochi","Synthesis of near-infrared absorbing triangular Au nanoplates using biomineralisation peptides",,"ACTA Biomaterialia",,,,,2021,June "平野 龍一郎,岡本 浩輝,新毛 実結,渡邉 仁美,近藤 玄,門之園 哲哉,近藤 科江","TNBC腫瘍における組織常在性間質細胞の解析","第15回日本分子イメージング学会総会・学術集会",,,,,,2021,May "峯岸美紗,門之園哲哉,近藤科江,口丸高弘","細胞間相互作用可視化光技術を使ったがん転移形成過程の 1 細胞オミクス解析","第15回日本分子イメージング学会総会・学術集会",,,,,,2021,May "稲葉千尋,澤田敏樹,門之園哲哉,芹澤武","高分子結合性ペプチドを利用する細胞イメージングの基盤構築","日本化学会第101春季年会",,,,,,2021,Mar. "平野龍一郎,岡本浩輝,門之園哲哉,渡邊仁美,近藤玄,近藤科江","血管新生前の早期トリプルネガティブ乳がんを用いた腫瘍内間質細胞の解析","第28回日本血管生物医学会",,,,,,2021,Mar. "Ryuichiro Hirano,Kouki Okamoto,Tetsuya Kadonosono,渡邊仁美,近藤玄,Shinae Kizaka-Kondoh","Analysis of intratumor stromal cells using early-stage triple-negative breast cancer before angiogenesis","第28回日本血管生物医学会学術集会",,,,,,2021,Mar. "門之園 哲哉","抗体構造情報を利用した分子標的ペプチドの創製","日本薬学会第141回大会シンポジウム『中分子創薬研究のフロンティア:〜生体分子を標的とした機能性ペプチドの創製〜』",,,,,,2021,Mar. "門之園 哲哉","スマートデザインによる高性能標的結合の創製","日本農薬学会第46回大会シンポジウム『生物と化学のはざまで』",,,,,,2021,Mar. "Tetsuya Kadonosono","Novel biopharmaceuticals for molecular target therapy of cancer. In silico design and evaluation of biopharmaceuticals","RWTH-Tokyo Tech Joint Workshop『In silico, AI, AR in Life Science』",,,,,,2021,Feb. "門之園 哲哉","知識・技術・人財融合による次世代医療モダリティ創発",,"MEDCHEM NEWS",,"Vol. 31","No. 1","pp. 43-45",2021,Feb. "M. Minegishi,T. Kuchimaru,K. Nakagawa,T. Isozaki,S. Fujimori,T. Kadonosono,S. Kizaka-Kondoh","Multiplexed bioluminescence imaging of cancer cell response to hypoxia and inflammation in the caudal-artery injection model of bone metastasis during zoledronic acid treatment",,"Journal of Cancer Metastasis and Treatment",,"Vol. 7","No. 5",,2021,Jan. "Diem Thi Phuong Tran,Takahiro Kuchimaru,Mongkol Pongsuchart,Kha The Nguyen,John Clyde L.Co Soriano,Tetsuya Kadonosono,Shinae Kizaka-Kondoh.","ROR2 regulates the survival of murine osteosarcoma cells in lung capillaries",,"Journal of Cancer Metastasis and Treatment",,"Vol. 15","No. 12",,2020,Dec. "門之園 哲哉","スマートデザインによる抗原結合小型タンパク質FLAPの創製","Yokohama Scientists Spotlight",,,,,,2020,Nov. "木田勇一,丹羽達也,澤田敏樹,門之園哲哉,丸山優史,岩崎富生,芹澤武","ファージディスプレイ法を利用したポリテトラフルオロエチレン結合性ペプチドの探索","第10回CSJ化学フェスタ2020",,,,,,2020,Oct. "平野龍一郎,岡本浩輝,門之園哲哉,星野歩子,渡邊仁美,近藤玄,近藤科江","トリプルネガティブ乳がんの早期悪性化に関与する間質細胞の解析","第79回日本癌学会学術集会",,,,,,2020,Oct. "Kyra See,Tetsuya Kadonosono,Kotaro Miyamoto,Wanaporn Yimchuen,Shinae Kizaka-Kondoh","Development of small HER2-binding proteins by paratope reconstitution","第79回日本癌学会学術集会",,,,,,2020,Oct. "栗生 識,門之園哲哉,近藤 科江,石田 忠","スフェロイドの免疫組織学的解析を可能とするマイクロ流体デバイス","第37回「センサ・マイクロマシンと応用システム」シンポジウム",,,,,,2020,Oct. "宮本康太郎,門之園哲哉,井上正宏,近藤科江","ミトコンドリア機能評価による休眠がん細胞標的薬剤の作用機構解析","第24回日本がん分子標的治療学会学術集会",,,,,,2020,Oct. "Kotaro Miyamoto,Tetsuya Kadonosono,Tomoyoshi Soga,Shinae Kondoh","Elucidation of mitochondrial energy metabolism in dormant cancer cells by multi-omics analysis","The Annual Meeting of Japanese Cancer Association",,,,,,2020,Oct. "Kyra See,Tetsuya Kadonosono,Yumi Ota,Kotaro Miyamoto,Wanaporn Yimchuen,Shinae Kizaka-Kondoh","Reconstitution of an anti-HER2 antibody paratope by grafting dual CDR-derived peptides onto a small protein scaffold",,"Biotechnology Journal",,,," e2000078",2020,Sept. "門之園 哲哉","スマートデザインによる抗体医薬代替小型タンパク質の創製","第93回日本生化学会シンポジウム『化学で攻める新しい創薬のカタチ』",,,,,,2020,Sept. "Tetsuya Kadonosono","A smart design of target-binding small proteins for molecular target therapy","第58回生物物理学会年会シンポジウム『Biomolecular Design to Control their Functions』",,,,,,2020,Sept. "門之園 哲哉","構造計算による抗原結合小型タンパク質デザインと創薬研究","生物工学フォーラム『情報解析が切り拓く創薬・生物工学研究の新展開』",,,,,,2020,Aug. "Kyra See,Tetsuya Kadonosono,Wanaporn Yimchuen,Shinae Kizaka-Kondoh","Double-CDR grafting for the development of small HER2-targeting proteins","第20回日本蛋白質科学会年会",,,,,,2020,July "本間 滉也,門之園 哲哉,YIMCHUEN WANAPORN,近藤 科江","Development of a bioluminescent imaging probe for detecting KISS1R-expressing cancers in vivo","第20回日本蛋白質科学会年会",,,,,,2020,July "木田勇一,丹羽達也,澤田敏樹,門之園哲哉,丸山優史,岩崎富生,芹澤武","ポリ(テトラフルオロエチレン)に結合するペプチドの探索と特性評価","第69回高分子年次大会",,,,,,2020,May "Satoru Kuriu,Tetsuya Kadonosono,Shinae Kizaka-Kondoh,Tadashi Ishida","Slicing spheroids in microfluidic devices for morphological and immunohistochemical analysis",,"Micromachines (Basel)",,"Vol. 11","No. 5","pp. E480",2020,May "Hitomi Miyabara,Ryuichiro Hirano,Takahiro Kuchimaru,Tetsuya Kadonosono,Hitomi Watanabe,Gen Kondoh,Shinae Kizaka-Kondoh","In vivo imaging of HIF-active cells in tumors using transgenic mice with a HIF-dependent reporter gene","AACR Annual Meeting 2020",,,,,,2020,Apr. "Wanaporn Yimchuen,Tetsuya Kadonosono,Yumi Ota,Shinichi Sato,Maika Kitazawa,Tadashi Shiozawa,Takahiro Kuchimaru,Masumi Taki,Yuji Ito,Hiroyuki Nakamura,Shinae Kizaka-Kondoh","Strategic design to create HER2-targeting proteins with target-binding peptides immobilized on a fibronectin type III domain scaffold",,"RSC Advances",,"Vol. 10",,"pp. 15154-15162",2020,Apr. "Shinichi Sato,Masaki Matsumura,Tetsuya Kadonosono,Satoshi Abe,Takafumi Ueno,Hiroshi Ueda,Hiroyuki Nakamura","Site-selective protein chemical modification of exposed tyrosine residues using tyrosine click reaction",,"Bioconjugate Chemistry",,,,,2020,Mar. "Tetsuya Kadonosono,Wanaporn Yimchuen,Yumi Ota,Kyra See,Tadaomi Furuta,Tadashi Shiozawa,Maika Kitazawa,Yu Goto,Akash Patil,Takahiro Kuchimaru,Shinae Kizaka-Kondoh","Design Strategy to Create Antibody Mimetics Harbouring Immobilised Complementarity Determining Region Peptides for Practical Use",,"Sci. Rep.",,"vol. 10",,"pp. 891",2020,Jan. "T. Kadonosono,S. Kizaka-Kondoh","Semi-rational Design of Target-binding Small Proteins for Cancer Treatment",,"Yakugaku Zasshi",,"Vol. 140","No. 2","pp. 159-162",2020,Jan. "K. Okuda,B. G. M. Youssif,R. Sakai,T. Ueno,T. Sakai,T. Kadonosono,Y. Okabe,O. I. Abdel R. Salem,A. M. Hayallah,M. A. Hussein,S. Kizaka-Kondoh,H. Nagasawa","Development of Near-Infrared Fluorescent Probes with Large Stokes Shifts for Non-Invasive Imaging of Tumor Hypoxia",,"Heterocycles",,"Vol. 101","No. 2","pp. 559-579",2020,Jan. "吉田有沙,渡邊重明,板倉祥子,田中武雄,門之園哲哉,近藤科江","生体適合性ナノデバイスを用いた腫瘍封止療法の開発","第17回がんとハイポキシア研究会",,,,,,2019,Nov. "S. Fuse,K. Suzuki,T. Kuchimaru,T. Kadonosono,H. Ueda,S. Sato,S. Kizaka-Kondoh,H. Nakamura","Design, synthesis, and evaluation of indeno[2,1-c]pyrazolones for use as inhibitors against hypoxia-inducible factor (HIF)-1 transcriptional activity",,"Bioorg. Med. Chem",,,,,2019,Nov. "Tetsuya Kadonosono,Wanaporn Yimchuen,Kyra See,Shinae Kizaka-Kondoh","A design strategy for developing practical antibody mimetic small proteins for cancer therapy","25th Symposium of Young Asian Biological Engineers’ Community (YABEC2019)",,,,,,2019,Nov. "門之園 哲哉","標的結合ペプチドを利用する小型タンパク質医薬デザイン","第2回モダリティ創薬デザイン研究会シンポジウム『成長するモダリティ創薬の展望』",,,,,,2019,Nov. "宮本康太郎,門之園哲哉,松尾禎之,広田喜一,近藤科江","エネルギー代謝測定による休眠がん細胞のミトコンドリア機能解析","第17回がんとハイポキシア研究会",,,,,,2019,Nov. "平野龍一郎,宮原瞳,門之園哲哉,口丸高弘,渡邊仁美,近藤玄,近藤科江","腫瘍内間質細胞のHIF 活性可視化による悪性化機構の解明","第17回がんとハイポキシア研究会",,,,,,2019,Nov. "相田一希,門之園哲哉,Kyra See,近藤科江","PD-1/PD-L1 シグナル阻害ペプチドのフェノタイプ・スクリーニング系の構築","第17回がんとハイポキシア研究会",,,,,,2019,Nov. "門之園 哲哉","構造計算を利用した高精度デザインペプチドライブラリー",,"医薬品開発における中分子領域(核酸医薬・ペプチド医薬品)での開発戦略","情報機構",,,,2019,Oct. "門之園 哲哉","産学異分野融合で挑む創薬技術の革新","BioJapan 2019",,,,,,2019,Oct. "See Kyra,Kadonosono Tetsuya,Yimchuen Wanaporn,Shinae Kondoh","Development of a small anti-HER2 antibody mimetic by double-CDR grafting","第56回ペプチド討論会",,,,,,2019,Oct. "See Kyra,Kadonosono Tetsuya,Yimchuen Wanaporn,Shinae Kondoh","Design of a small and high-affinity anti-HER2 antibody mimetic by double-CDR grafting","第78回日本癌学会学術総会",,,,,,2019,Sept. "門之園 哲哉","抗体医薬の代替となる小型タンパク質の半合理デザイン","第71会日本生物工学会 シンポジウム『タンパク質工学におけるドライ-ウェット技術融合の新展開』",,,,,,2019,Sept. "門之園 哲哉","標的結合ペプチドを搭載した小型タンパク質FLAPのデザイン","第51回若手ペプチド夏の勉強会",,,,,,2019,Aug. "Tetsuya Kadonosono","A design strategy for generating cancer marker-binding small proteins","Nano-Bio Research-Industry International Symposium 2019",,,,,,2019,July "Tetsuya Kadonosono,Kyra See,Wanaporn Yimchuen,Shinae Kizaka-Kondoh","A design strategy for creating a small and high-affinity antibody mimetics by double-CDR grafting","11th International Peptide Symposium",,,,,,2019,June "Wanaporn Yimchuen,Tetsuya Kadonosono,Shinichi Sato,Takahiro Nomoto,Kyra See,Hiroyuki Nakamura,Nobuhiro Nishiyama,Shinae Kizaka-Kondoh","Development of photoimmunotherapy probe using a small antibody mimetic with structurally constrained anti-HER2 CDR peptides","11th International Peptide Symposium",,,,,,2019,June "門之園 哲哉,近藤 科江","CDRペプチドの構造ゆらぎ制御による抗体代替小型タンパク質デザイン",,"ペプチド創薬の最前線","シーエムシー出版",,,,2019,May "門之園 哲哉,近藤 科江","構造計算に基づく標的結合小型タンパク質の創製とがん治療への応用","日本薬学会 第139年会 シンポジウム『創薬におけるタンパク質の魅力』",,,,,,2019,Mar. "門之園 哲哉","小型タンパク質FLAPの半合理的デザインと医薬応用","第7回蛋白質間相互作用研究会",,,,,,2019,Mar. "門之園 哲哉","抗体医薬品を代替する標的結合小型タンパク質デザイン","バイオファーマジャパン2019",,,,,,2019,Mar. "Tetsuya Kadonosono","A design strategy for creating antibody mimetic small proteins for cancer treatment","Japan-Taiwan International Engineering Forum 2019",,,,,,2019,Feb. "門之園 哲哉","抗原結合小型タンパク質のsemi-rationalデザインと医薬応用","LiHub創薬技術革新Gワークショップ『創薬関連研究の最先端』",,,,,,2019,Feb. "Maho Kaminaga,Tadashi Ishida,Tetsuya Kadonosono,Shinae Kizaka-Kondoh,Toru Omata","Microfluidic device for screening for target cell-specific binding molecules by using adherent cells",,"Micromachines (Basel)",,"Vol. 10","No. 1","pp. E41",2019,Jan. "Tetsuya Kadonosono,Wanaporn Yimchuen,Kyra See,Yumi Ota,Marina Katsumi,Takahiro Kuchimaru,Shinae Kizaka-Kondoh","A design strategy for creating practical middle-molecular-mass antibody mimetics having structurally constrained HER2-binding peptides","10th International Peptide Symposium",,,,,,2018,Dec. "Kyra See,Tetsuya Kadonosono,Wanaporn Yimchuen,Takahiro Kuchimaru,Shinae Kizaka-Kondoh","Production of a small and high-affinity HER2-binding protein by double-CDR grafting","10th International Peptide Symposium",,,,,,2018,Dec. "Marina Katsumi,Tetsuya Kadonosono,Kyra See,Takahiro Kuchimaru,Shinae Kizaka-Kondoh","Development of platform for generating antibody mimetics harboring constrained CDR peptides","10th International Peptide Symposium",,,,,,2018,Dec. "Kazuto Mochizuki,Tetsuya Kadonosono,Yuji Ito,Masumi Taki","Development of general method to obtain targeted fluorescent covalent binder","10th International Peptide Symposium",,,,,,2018,Dec. "Ryo Masuda,Tetsuya Kadonosono,Takaki Koide","Selection of bioactive peptides from a random triple-helical peptide library in yeast cells","10th International Peptide Symposium",,,,,,2018,Dec. "Kazuki Aida,Tetsuya Kadonosono,Takahiro Kuchimaru,Masumi Taki,Yuji Ito,Shinae Kizaka-Kondoh","Binding mode analysis of PD-1 targeting small protein having structurally constrained peptide","10th International Peptide Symposium",,,,,,2018,Dec. "Wanaporn Yimchuen,Tetsuya Kadonosono,Shinichi Sato,Kyra See,Takahiro Kuchimaru,Hiroyuki Nakamura,Shinae Kizaka-Kondoh","Creation of a small antibody mimetic immunoprobe with structurally constrained anti-HER2 CDR peptides","10th International Peptide Symposium",,,,,,2018,Dec. "Yumi Ota,Tetsuya Kadonosono,Takahiro Kuchimaru,Masumi Taki,Yuji Ito,Shinae Kizaka-Kondoh","Development of high affinity HER2-targeting small protein harboring a structurally constrained peptide","10th International Peptide Symposium",,,,,,2018,Dec. "太田 優美,門之園 哲哉,口丸 高弘,瀧 真清,伊東 祐二,近藤 科江","ヒトフィブロネクチンIII型ドメインを足場とする高親和性HER2結合小型分子の創製","第41回日本分子生物学会年会",,,,,,2018,Nov. "藤森 慧,口丸 高弘,峯岸 美紗,門之園 哲哉,近藤 科江","間葉系幹細胞による骨転移巣の形成制御メカニズムの解析","第41回日本分子生物学会年会",,,,,,2018,Nov. "相田 一希,門之園 哲哉,口丸 高弘,瀧 真清,伊東 祐二,近藤 科江","構造ゆらぎ抑制ペプチドを組み込んだPD-1結合小型タンパク質の結合解析","第41回日本分子生物学会年会",,,,,,2018,Nov. "平野 龍一郎,宮原 瞳,門之園 哲哉,口丸 高弘,渡邉 仁美,近藤 玄,近藤 科江","高感度発光イメージングによる腫瘍内間質細胞のHIF可視化による免疫抑制機構の解明","第41回日本分子生物学会年会",,,,,,2018,Nov. "瀬尾 美鈴,吉田 亜佑美,上野 信洋,Gargi Palashikar,早田 優香,太田 成美,永安 良多,栃尾 凌太,福光 一生,中西 聖磨,米倉 寛人,山口 淳史,浅野 弘嗣,門之園 哲哉,近藤 科江,扇田 久和,清水 昭男","VEGF-A/ニューロピリン1のシグナル伝達を阻害する細胞透過性ペプチドはがん細胞の浸潤と転移を抑制する。","第41回日本分子生物学会年会",,,,,,2018,Nov. "相田 一希,門之園 哲哉,口丸 高弘,近藤 科江","T細胞活性化抗体医薬の代替となるPD-1結合小型タンパク質の創製","第16回がんとハイポキシア研究会",,,,,,2018,Nov. "平野 龍一郎,宮原 瞳,門之園 哲哉,口丸 高弘,近藤 科江","腫瘍内間質細胞のHIF活性可視化による免疫抑制機構の解明のための高感度発光イメージングレポーター遺伝子の構築","第16回がんとハイポキシア研究会",,,,,,2018,Nov. "藤森 慧,峯岸 美紗,口丸 高弘,門之園 哲哉,近藤 科江","間葉系幹細胞による骨転移巣の形成制御メカニズムの解析","第16回がんとハイポキシア研究会",,,,,,2018,Nov. "門之園 哲哉,Wanaporn Yimchuen,太田 優美,Kyra See,口丸 高弘,近藤 科江","転写因子HIF活性を抑制するHER2結合小型タンパク質の創製","第16回がんとハイポキシア研究会",,,,,,2018,Nov. "平野 龍一郎,宮原 瞳,門之園 哲哉,口丸 高弘,渡邉 仁美,近藤 玄,近藤 科江","高感度発光イメージングによる腫瘍内間質細胞のHIF可視化による免疫抑制機構の解明","第41回日本分子生物学会年会",,,,,,2018,Nov. "遠藤 みのり,門之園 哲哉,口丸 高弘,井上 正宏,近藤 科江","休眠がん細胞に細胞死を誘導できる薬剤の作用機序解析と薬効評価","第41回日本分子生物学会年会",,,,,,2018,Nov. "勝見 茉莉奈,Kyra See,門之園 哲哉,口丸 高弘,近藤 科江","CDRペプチドを組み込んだ抗体医薬代替中分子の創薬プラットフォーム構築","第41回日本分子生物学会年会",,,,,,2018,Nov. "神永 真帆,石田 忠,門之園 哲哉,近藤 科江,小俣 透","ペプチド探索マイクロ流路デバイスにおける非標的細胞結合ペプチド除去性能の向上","第35回「センサ・マイクロマシンと応用システム」シンポジウム",,,,,,2018,Oct. "平野 龍一郎,宮原 瞳,門之園 哲哉,口丸 高弘,渡邊 仁美,近藤 玄,近藤 科江","腫瘍内間質細胞のHIF活性可視化による免疫抑制機構の解明のための高感度発光イメージングレポータ遺伝子の構築","In vivo イメージングフォーラム2018",,,,,,2018,Oct. "Wanaporn Yimchuen,Tetsuya Kadonosono,Kyra See,Takahiro Kuchimaru,Shinae Kondoh","Functional analysis of high-affinity antibody mimetics with structurally constrained CDR peptides for tumor imaging","In vivo イメージングフォーラム2018",,,,,,2018,Oct. "門之園 哲哉","Drug discovery cloudによる創薬技術革新への挑戦","BioJapan 2018",,,,,,2018,Oct. "近藤 科江,口丸 高弘,門之園 哲哉","新規MDSC様接着細胞の腫瘍免疫抑制環境形成における機能解析","第77回日本癌学会学術集会",,,,,,2018,Sept. "Mongkol Pongsuchart,Takahiro Kuchimaru,Tetsuya Kadonosono,Shinae Kondoh","Involvement of lymphoid enhancer binding factor 1/Cytoglobin axis in lung metastasis of osteosarcoma","第77回日本癌学会学術集会",,,,,,2018,Sept. "Mongkol Pongsuchart,Takahiro Kuchimaru,Sakiko Yonezawa,Diem Thi Phuong Tran,Nguyen The Kha,Ngoc Thi Hong Hoang,Tetsuya Kadonosono,Shinae Kondoh","Novel lymphoid enhancer-binding factor 1-cytoglobin axis promotes extravasation of osteosarcoma cells into the lungs",,"Cancer Science",,"Vol. 109","No. 9","pp. 2746-2756",2018,Sept. "Shinae Kizaka-Kondoh,Mongkol Pongsuchart,Diem Thi Phuong Tran,Tetsuya Kadonosono,Takahiro Kuchimaru","Osteosarcoma cell lines with different metastatic potential isolated by Image-guided screening revealed a novel LEF1-CYGB axis that promotes extravasation of osteosarcoma cells into the lungs","World Molecular Imaging Congress 2018",,,,,,2018,Sept. "遠藤 みのり,門之園 哲哉,口丸 高弘,Inoue Masahiro,近藤 科江","休眠がん細胞に細胞死を誘導できる薬剤の作用機序解析", 第77回日本癌学会学術集会","第77回日本癌学会学術集会",,,,,,2018,Sept. "太田 優美,門之園 哲哉,口丸 高弘,近藤 科江","構造ゆらぎ抑制標的結合ペプチドを組み込んだ小型HER2結合分子の機能評価","第77回日本癌学会学術集会",,,,,,2018,Sept. "Wanaporn Yimchuen,Tetsuya Kadonosono,Takahiro Kuchimaru,Shinae Kondoh","Functional analysis of high-affinity antibody mimetics with structurally constrained CDR peptides for tumor imaging","第77回日本癌学会学術集会",,,,,,2018,Sept. "太田 優美,門之園 哲哉,口丸 高弘,瀧 真清,伊東 祐二,近藤 科江","標的結合ペプチドの構造ゆらぎ抑制によるHER2結合小型タンパク質の創製","第50回若手ペプチド夏の勉強会",,,,,,2018,Aug. "Koh K. Takita,Kazunori K. Fujii,Tetsuya Kadonosono,Ryo Masuda,Takaki Koide","Cyclic Peptides for Efficient Detection of Collagen",,"Chembiochem",,"Vol. 19","No. 15","pp. 1613-1617",2018,Aug. "相田 一希,門之園 哲哉,口丸 高弘,瀧 真清,伊東 祐二,近藤 科江","足場小型タンパク質により構造ゆらぎを抑制したPD-1結合ペプチドの機能評価と配列最適化","第50回若手ペプチド夏の勉強会",,,,,,2018,Aug. "勝見 茉莉奈,門之園 哲哉,Kyra See,口丸 高弘,近藤 科江","抗体CDRペプチドを組み込んだ抗原結合中分子の迅速創製プラットフォームの構築","第50回若手ペプチド夏の勉強会",,,,,,2018,Aug. "Takahiro Kuchimaru,Naoya Kataoka,Kenji Nakagawa,Tatsuhiro Isozaki,Hitomi Miyabara,Misa Minegishi,Tetsuya Kadonosono,Shinae Kondoh","A reliable murine model of bone metastasis by injecting cancer cells through caudal arteries",,"Nat Commun",,"Vol. 9","No. 1","pp. 2981",2018,July "Wanaporn Yimchuen,Tetsuya Kadonosono,Kyra See,Takahiro Kuchimaru,Shinae Kondoh","Development of high-affinity tumor imaging probes with structurally constrained CDR peptides","第13回日本分子イメージング学会総会・学術集会",,,,,,2018,June "Mongkol Pongsuchart,Takahiro Kuchimaru,Tetsuya Kadonosono,Shinae Kondoh","In vivo image-guided screening and genome-wide meta-analysis revealed involvement of LEF1/Cytoglobin axis in lung metastasis of osteosarcoma","第13回日本分子イメージング学会総会・学術集会",,,,,,2018,May "太田 優美,門之園 哲哉,口丸 高弘,近藤 科江","標的結合ペプチドの構造ゆらぎ抑制による高親和性HER2結合小型タンパク質の創製","第22回日本がん分子標的治療学会学術集会",,,,,,2018,May "藤森 慧,礒崎 達大,峯岸 美紗,口丸 高弘,門之園 哲哉,近藤 科江","生物発光イメージングに基づいた骨転移成長を促進する因子の同定","第13回日本分子イメージング学会総会・学術集会",,,,,,2018,May "相田 一希,門之園 哲哉,口丸 高弘,近藤 科江","T細胞活性化抗体医薬の代替となる低分子量PD-1結合タンパク質の創製","第22回日本がん分子標的治療学会学術集会",,,,,,2018,May "遠藤 みのり,門之園 哲哉,口丸 高弘,井上 正宏,近藤 科江","ALK陽性非小細胞肺がん細胞株を用いた休眠がん細胞標的薬剤の薬効評価","第22回日本がん分子標的治療学会学術集会",,,,,,2018,May "宮原 瞳,口丸 高弘,門之園 哲哉,水島 友子,浦野 浩司,近藤 科江","HIF 活性可視化トランスジェニックマウスを用いた腫瘍内 HIF 活性化細胞のイメージング","第13回日本分子イメージング学会総会・学術集会",,,,,,2018,May "Tetsuya Kadonosono,Yumi Ota,Wanaporn Yimchuen,Kyra See,Tadaomi Furuta,Takahiro Kuchimaru,Shinae Kondoh","Creation of High Performance Antibody Drug Alternatives Harboring Constrained CDR Peptides",,"PEPTIDE SCIENCE 2017 (I. Fujii (ed.))","The Japanese Peptide Society, Osaka",,,"pp. 126-127",2018,Mar. "第6回蛋白質間相互作用研究会,門之園 哲哉","抗体代替中分子の半合理的デザイン","第6回蛋白質間相互作用研究会",,,,,,2018,Mar. "Takuya Tsubaki,Tetsuya Kadonosono,Shimon Sakurai,Tadashi Shiozawa,Toshiki Goto,Shiori Sakai,Takahiro Kuchimaru,Takeharu Sakamoto,Hitomi Watanabe,Gen Kondoh,Shinae Kizaka-Kondoh","Novel adherent CD11b+ Gr-1+ tumor-infiltrating cells initiate an immunosuppressive tumor microenvironment",,"Oncotarget",,"Vol. 9","No. 13","pp. 11209",2018,Feb. "遠藤 みのり,門之園 哲哉,酒井 栞,口丸 高弘,井上 正宏,近藤 科江","ALK陽性肺がん細胞株による休眠がん細胞標的薬剤の薬効評価","2017年度生命科学系学会合同年次大会",,,,,,2017,Dec. "伊藤 雄大,門之園 哲哉,口丸 高弘,近藤 科江","HIFが活性化したがんを標的とした新規融合タンパク質製剤の機能評価","2017年度生命科学系学会合同年次大会",,,,,,2017,Dec. "口丸 高弘,磯崎 達大,宮原 瞳,峯岸 美紗,門之園 哲哉,近藤 科江","簡便かつ高効率な骨髄への細胞デリバリー手法の開発","2017年度生命科学系学会合同年次大会",,,,,,2017,Dec. "峯岸 美紗,口丸 高弘,藤森 慧,磯崎 達大,門之園 哲哉,近藤 科江","マルチ生物レポーターシステムを用いた骨転移発症過程における前立腺がんと骨髄間質細胞の相互作用解析","2017年度生命科学系学会合同年次大会",,,,,,2017,Dec. "門之園 哲哉,Wanaporn Yimchuen,Kyra See,太田 優美,口丸 高弘,近藤 科江","抗体CDRペプチドの構造ゆらぎ制御による小型抗体代替分子の創製","2017年度生命科学系学会合同年次大会",,,,,,2017,Dec. "太田 優美,門之園 哲哉,口丸 高弘,瀧 真清,伊東 祐二,近藤 科江","ヒトフィブロネクチンIII型ドメインを足場とする小型HER2結合分子の創製","2017年度生命科学系学会合同年次大会",,,,,,2017,Dec. "門之園 哲哉","化学合成可能な高性能抗体代替分子の開発技術",,"ペプチド医薬品開発のためのスクリーニング・安定化・製剤化技術","技術情報協会",,,,2017,Dec. "Misa Minegishi,Tatsuhiro Isozaki,Satoshi Fujimori,Takahiro Kuchimaru,Tetsuya Kadonosono,Shinae Kizaka-Kondoh","A multi-bioluminescence reporter system visualizes crosstalk between cancer cells and bone marrow microenvironment","Taiwan-Japan Join Meeting on Bioimaging for Young Researchers",,,,,,2017,Nov. "YIMCHUEN WANAPORN,門之園 哲哉,Kyra See,古田 忠臣,口丸 高弘,近藤 科江","Development of anti-HER2 antibody mimetics with structurally constrained CDR peptides","第54回ペプチド討論会",,,,,,2017,Nov. "門之園 哲哉,太田 優美,YIMCHUEN WANAPORN,Kyra See,古田 忠臣,口丸 高弘,近藤 科江","Creation of high performance antibody drug alternatives harboring constrained CDR peptides","第54回ペプチド討論会",,,,,,2017,Nov. "門之園 哲哉,Kyra See,勝見 茉莉奈,太田 優美,Wanaporn Yimchuen,相田 一希,口丸 高弘,近藤 科江","腫瘍悪性化促進因子の活性を中和する抗体代替分子の創製","第15回がんとハイポキシア研究会",,,,,,2017,Nov. "椿 卓也,門之園 哲哉,口丸 高弘,近藤 科江","新規接着性ミエロイド細胞の同定とそれによる腫瘍悪性化機構の解析","第15回がんとハイポキシア研究会",,,,,,2017,Nov. "酒井 栞,門之園 哲哉,遠藤 みのり,口丸 高弘,井上 正宏,近藤 科江","肺がん細胞株を用いた休眠がん細胞標的薬剤の作用機構の解析","第15回がんとハイポキシア研究会",,,,,,2017,Nov. "礒崎 達大,藤森 慧,峯岸 美紗,口丸 高弘,門之園 哲哉,近藤 科江","早期骨転移形成過程におけるがん細胞と骨髄間質細胞の相互作用の役割","第15回がんとハイポキシア研究会",,,,,,2017,Nov. "Yumi Ota,Tetsuya Kadonosono,Takahiro Kuchimaru,Masumi Taki,Yuji Ito,Shinae Kondoh","Development of HER2-targeting small protein harboring a structurally constrained peptide","第54回ペプチド討論会",,,,,,2017,Nov. "片岡 直也,口丸 高弘,礒崎 達大,宮原 瞳,門之園 哲哉,近藤 科江","がん細胞の尾動脈移植によるマウス骨転移モデルの簡便な構築","第75回日本癌学会学術総会",,,,,,2017,Oct. "Shusei Hamamichi,Izumi O Umeda,門之園 哲哉,口丸 高弘,近藤 科江,Hirofumi Fujii","125I Radiolabeling and Biodistribution Analysis of a Novel Anti-cancer Agent TOP3","The 12th Asia Oceania Congress of Nuclear Medicine and Biology",,,,,,2017,Oct. "磯崎 達大,峯岸 美紗,口丸 高弘,門之園 哲哉,近藤 科江","早期骨転移形成過程におけるがん細胞と骨髄間質細胞のクロストーク解析","The 76th Annual Meeting of the Japanese Cancer Association",,,,,,2017,Sept. "Yumi Ota,Tetsuya Kadonosono,Wanaporn Yimchuen,Takahiro Kuchimaru,Shinae Kondoh","Development of high affinity anti-HER2 antibody mimetics by use of human fibronectin type III domain","The 76th Annual Meeting of the Japanese Cancer Association",,,,,,2017,Sept. "Shiori Sakai,Tetsuya Kadonosono,Minori Endo,Takahiro Kuchimaru,Masahiro Inoue,Shinae Kondoh","Analysis of the functional mechanism of a drug targeting dormant cancer cells by using a lung cancer cell line","The 76th Annual Meeting of the Japanese Cancer Association",,,,,,2017,Sept. "Shusei Hamamichi,Izumi Umeda,Tetsuya Kadonosono,Takahiro Kuchimaru,Shinae Kizaka-Kondoh,Hirofumi Fujii","Retention of 125I-TOP3 in the Tumor of a HIF1α-positive Cancer Xenograft Model","The 76th Annual Meeting of the Japanese Cancer Association",,,,,,2017,Sept. "門之園 哲哉,太田 優美,YIMCHUEN WANAPORN,口丸 高弘,近藤 科江","A screening system for identifying biocompatible low-molecular-mass scaffold proteins to develop small antibody mimetics","The 76th Annual Meeting of the Japanese Cancer Association",,,,,,2017,Sept. "Pongsuchart M,Kuchimaru T,Kadonosono T,Kondoh S","Identification and characterization of genes associated with osteosarcoma extravasation into the lung","The 76th Annual Meeting of the Japanese Cancer Association",,,,,,2017,Sept. "Tran D,Kondoh S,Kuchiamru T,Kadonosono T,Pongsuchart M,Yonezawa S","Analysis of regulatory mechanisms osteosarcoma lung metastasis via Wnt signaling","The 76th Annual Meeting of the Japanese Cancer Association",,,,,,2017,Sept. "Tatsuhiro Isozaki,Misa Minegishi,Naoya Kataoka,Takahiro Kuchimaru,Tetsuya Kadonosono,Shinae Kondoh","Analysis of molecular mechanisms governing outgrowth of bone metastasis by using a multi-bioluminescence reporter system","2017 KSMI-FASMI Joint Conference",,,,,,2017,Aug. "太田 優美,門之園 哲哉,口丸 高弘,瀧 真清,伊東 祐二,近藤 科江","構造ゆらぎ抑制による抗HER2抗体代替分子の創製","第49回若手ペプチド夏の勉強会",,,,,,2017,Aug. "近藤科江,口丸高弘,門之園哲哉","体生体光イメージングを用いた創薬研究","第39回日本光医学・光生物学会",,,,,,2017,July "太田優美,門之園哲哉,口丸高弘,近藤科江","ヒトフィブロネクチン?型ドメインを利用した抗HER2抗体代替分子の開発","第21回日本がん分子標的治療学会学術集会",,,,,,2017,June "門之園哲哉","構造ゆらぎ制御による小型抗体代替分子の創出","第3回 蛋白質工学研究会ワークショップ 『小分子抗体関連技術』",,,,,,2017,June "遠藤みのり,門之園哲哉,酒井栞,口丸高弘,井上 正宏,近藤科江","肺がん細胞株を用いた休眠がん細胞標的薬剤の治療有効性評価","第21回日本がん分子標的治療学会学術集会",,,,,,2017,June "口丸高弘,片岡直也,門之園哲哉,近藤科江","尾動脈移植による簡便かつ高効率な骨転移モデルマウス","第21回日本がん分子標的治療学会学術集会",,,,,,2017,June "門之園哲哉,太田優美,口丸高弘,近藤科江","小型抗体代替分子の創出に向けた低分子量足場タンパク質の探索","第21回日本がん分子標的治療学会学術集会",,,,,,2017,June "遠藤 みのり,門之園 哲哉,酒井 栞,口丸 高弘,近藤 科江","再発性肺がんモデルマウスの生体発光イメージング","第12回日本分子イメージング学会総会・学術集会",,,,,,2017,May "口丸 高弘,片岡 直也,礒崎 達大,宮原 瞳,門之園 哲哉,近藤 科江","尾動脈移植法による新規血行性骨転移モデルマウス","第12回日本分子イメージング学会総会・学術集会",,,,,,2017,May "礒崎 達大,峯岸 美紗,片岡 直也,口丸 高弘,門之園 哲哉,近藤 科江","Analysis of molecular mechanisms governing outgrowth of bone metastasis by using a multi-bioluminescence reporter system","第12回日本分子イメージング学会総会・学術集会",,,,,,2017,May "椿 卓也,門之園 哲哉,口丸 高弘,近藤 科江","in vivo光イメージングを用いた新規ミエロイド細胞F4/80(-)AMCの機能解析","第12回日本分子イメージング学会総会・学術集会",,,,,,2017,May "TRAN T.PHUONG DIEM,PONGSUCHART M,米澤 早紀子,口丸 高弘,門之園 哲哉,近藤 科江","Identification of downstream genes of Wnt signaling regulating osteosarcoma extravasation into the lung","第12回日本分子イメージング学会総会・学術集会",,,,,,2017,May "濱道 修生,梅田 泉,門之園 哲哉,近藤 科江,藤井 博史","HIF-1α活性陽性領域を標的とする新規抗がん剤TOP3の体内挙動の検討","第12回日本分子イメージング学会総会・学術集会",,,,,,2017,May "口丸 高弘,片岡 直也,磯崎 達大,宮原 瞳,門之園 哲哉,近藤 科江","尾動脈移植法による新規血行性骨転移モデルマウス","第12回日本分子イメージング学会総会・学術集会",,,,,,2017,May "礒崎 達大,峯岸 美紗,片岡 直也,口丸 高弘,門之園 哲哉,近藤 科江","Analysis of molecular mechanisms governing outgrowth of bone metastasis by using a multi-bioluminescence reporter system","第12回日本分子イメージング学会総会・学術集会",,,,,,2017,May "YIMCHUEN WANAPORN,門之園 哲哉,古田 忠臣,口丸 高弘,近藤 科江","Development of high-affinity tumor imaging probes based on constrained target-binding peptides","第12回日本分子イメージング学会学術集会",,,,,,2017,May "石田忠,田中優弥,門之園哲哉,近藤科江,小俣透","スラグ内部循環流によるペプチドのがん細胞スフェロイドへの付着効率の向上","ロボティクス・メカトロニクス講演会2017",,,,,,2017,May "門之園哲哉","構造ゆらぎ制御による高親和性PD-1結合ペプチド医薬の創製戦略","ペプチド医薬品における活性,安定性,吸収性改善",,,,,,2017,Apr. "T. Kadonosono,W. Yimchuen,T. Tsubaki,T. Shiozawa,Y. Suzuki,T. Kuchimaru,Y. Sato,S. Kizaka-Kondoh","Domain architecture of vasohibins required for their chaperone-dependent unconventional extracellular release",,"Protein Sci",,"Vol. 26","No. 3","pp. 452-463",2017,Mar. "門之園哲哉","構造ゆらぎの抑制による抗体代替分子の創製","第5回蛋白質間相互作用研究会",,,,,,2017,Mar. "門之園 哲哉,鈴木 康弘,口丸 高弘,佐藤 靖史,近藤 科江","細胞外分泌に必須のVASHドメイン構造の解析","第12回Vasohibin研究会",,,,,,2017,Feb. "門之園哲哉","構造ゆらぎ制御による抗体代替分子の創製","第2回マイクロプロテイン研究会",,,,,,2017,Jan. "Shinae Kondoh,Takahiro Kuchimaru,Tetsuya Kadonosono","Symposium 5: The roles of vascular remodeling in tissue hypoxia Imaging strategies for detection of HIF activity","The 24th Annual Meeting of the Japanese Vascular Biology and Medicine Organization",,,,,,2016,Dec.