"M. Matsui,Y. Kaihara,Y. Honda,N Nishiyama,Y. Miura","Site-activatable targeting of macromolecular alendronate for accelerated fracture healing",,"Sci. Technol. Adv. Mater.",,"Vol. 24","No. 1","pp. 2286218",2023,Dec. "M. Nakao,M. Matsui,K. Kim,N. Nishiyama,D.W. Grainger,T. Okano,H. Kanazawa,K. Nagase","Umbilical cord-derived mesenchymal stem cell sheets transplanted subcutaneously enhance cell retention and survival more than dissociated stem cell injections",,"Stem Cell Res. Ther.",,"Vol. 14","No. 1","pp. 352",2023,Dec. "Shan Gao,Y. Miura,A. Sumiyoshi,S. Ohno,K. Ogata,T. Nomoto,M. Matsui,Y. Honda,M. Suzuki,M. Iiyama,K. Osada,I. Aoki,N. Nishiyama","Self-folding macromolecular drug carrier for cancer imaging and therapy",,"Advanced Science",,"Vol. 11","No. 7","pp. e2304171",2023,Nov. "Haochen Guo,Xu Wen,Takahiro Nomoto,Kaito Kanamori,Yan Ming Voon,Yuto Honda,Naoki Yamada,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","Polymeric ligands comprising sulfur-containing amino acids for targeting tumor-associated amino acid transporters.",,"Biomaterials",,"Vol. 293",,"pp. 121987",2023,Feb. "Yijung Sung,Haochen Guo,Aria Ghasemizadeh,Xin Shen,Wanphiwat Chintrakulchai,Motoaki Kobayashi,Masahiro Toyoda,Koichi Ogi,Junya Michinishi,Tokoyuki Ohtake,Makoto Matsui,Yuto Honda,Takahiro Nomoto,Hiroyasu Takemoto,Yutaka Miura,Nobuhiro Nishiyama","Cancerous pH-responsive polycarboxybetaine-coated lipid nanoparticle for smart delivery of siRNA against subcutaneous tumor model",,"Cancer Science",,"Vol. 113","No. 12","pp. 4339-4349",2022,Oct. "Yuto Honda,Sayaka Onodera,Hiroyasu Takemoto,Faizah Noor,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Yudi Sun,Yutaka Miura,Nobuhiro Nishiyama","Thermo-responsive polymer-siRNA conjugates enabling artificial control of gene silencing around body temperature",,"Pharmaceutical Research",,"Vol. 40","No. 1","pp. 157-165",2022,Oct. "Xue Xie,Yuta Kurashina,Makoto Matsui,Takahiro Nomoto,Munenari Itoh,Hirotaka J Okano,Kentaro Nakamura,Nobuhiro Nishiyama,Yoshitaka Kitamoto","Transdermal delivery of bFGF with sonophoresis facilitated by chitosan nanocarriers",,"Elsevier",,"vol. 75",," 103675",2022,Sept. "Aziz Awaad,Hiroyasu Takemoto,Muneaki Iizuka,Koichi Ogi,Yuki Mochida,Abdul-Hackam Ranneh,Masahiro Toyoda,Makoto Matsui,Takahiro Nomoto,Yuto Honda,Kotaro Hayashi,Keishiro Tomoda,Tomoyuki Ohtake,Yutaka Miura,Nobuhiro Nishiyama","Changeable net charge on nanoparticles facilitates intratumor accumulation and penetration",,"Journal of Controlled Release",,"Vol. 346",,"pp. 392-404",2022,May "本田雄士,長尾周平,喜納宏昭,野本貴大,Liu Xueying,Dirisala Anjaneyulu,松井誠,三浦裕,片岡一則,西山伸宏","アデノ随伴ウイルス(AAV)の中和抗体回避および活性を向上させるAAV内包三元系複合体","日本薬学会第142回年会",,,,,,2022,Mar. "松尾拓海,本田雄士,野本貴大,松井誠,三浦裕,西山伸宏","タンニン酸とフェニルボロン酸導入高分子で構築されたCas9 RNPデリバリーシステムの開発","日本薬学会第142回年会",,,,,,2022,Mar. "Yuta Kurashina,Risa Asano,Makoto Matsui,Takahiro Nomoto,Keita Ando,Kentaro Nakamura,Nobuhiro Nishiyama,Yoshitaka Kitamoto","Quantitative analysis of acoustic pressure for sonophoresis and its effect on transdermal penetration",,,,,,,2022,Feb. "Guo H.,Nomoto T.,Muttaqien S.E.,Sun X.,Komoto K.,Matsui M.,Miura Y.,Nishiyama N.","A polymeric iron chelator enhancing pro-oxidant antitumor efficacy of vitamin C by inhibiting extracellular Fenton reaction",,"Molecular Pharmaceutics",,"Vol. 18","Issue 12",,2021,Dec. "Yuto Honda*,Takahiro Nomoto,Makoto Matsui,Hiroyasu Takemoto,Yutaka Miura,Nobuhiro Nishiyama*","Sequentially Self-Assembled Nanoreactor Comprising Tannic Acid and Phenylboronic Acid-Conjugated Polymers Inducing Tumor-Selective Enzymatic Activity",,"ACS Applied Materials and Interfaces",,"Vol. 13","No. 46","pp. 54850?54859",2021,Nov. "長尾周平,本田雄士,喜納宏昭,野本貴大,Liu Xueying,Dirisala Anjaneyulu,松井誠,三浦裕,片岡一則,西山伸宏","アデノ随伴ウイルス(AAV)中和抗体回避を可能にする全身投与型AAV搭載三元系複合体の開発","第43回日本バイオマテリアル学会大会",,,,,,2021,Nov. "本田雄士,山田直生,野本貴大,松井誠,西山伸宏","グルタミントランスポーターを高密度で発現しているがん細胞を認識する機能性高分子の開発","第43回日本バイオマテリアル学会大会",,,,,,2021,Nov. "松尾拓海,本田雄士,野本貴大,松井誠,三浦裕,西山伸宏","タンニン酸とフェニルボロン酸導入高分子の自己会合によって構成されたCas9 RNPデリバリーシステムの開発","第11回CSJ化学フェスタ2021",,,,,,2021,Oct. "Yuta Kurashina,Risa Asano,Makoto Matsui,Takahiro Nomoto,Kentaro Nakamura,Nobuhiro Nishiyama,Yoshitaka Kitamoto","Measurement and calculation of acoustic pressure on the effect of transdermal penetration by sonophoresis","The 42nd Symposium on Ultrasonic Electronics",,,,,,2021,Oct. "Takahiro Nomoto,Yukiya Inoue,Ying Yao,Kaito Kanamori,Minoru Suzuki,Kakeru Konarita,Makoto Matsui,Nobuhiro Nishiyama","Synthesis of functional polymers boosting therapeutic potential of p-boronophenylalanine and analysis of the effect of their physicochemical properties on pharmacokinetics","19th International Congress on Neutron Capture Therapy (19th ICNCT)",,,,,,2021,Sept. "臼倉幸一,本田雄士,野本貴大,松井誠,三浦裕,西山伸宏","官能基が異なるボロン酸導入高分子とタンニン酸で構成されたタンパク質三元系複合体の安定性評価","第70回高分子討論会",,,,,,2021,Sept. "Guo Haochen,野本貴大,松井誠,VOONYAN MING,SUNGYi-Jung,三浦裕,西山伸宏","高分子鉄キレート剤を利用した腫瘍免疫逃避環境の克服","第70回高分子討論会",,,,,,2021,Sept. "本田雄士,野本貴大,松井誠,三浦裕,西山伸宏","効率的なタンパク質送達を指向したタンニン酸とフェニルボロン酸導入高分子で構成されたタンパク質内包三元系複合体の構築","第70回高分子討論会",,,,,,2021,Sept. "松尾拓海,本田雄士,野本貴大,松井誠,三浦裕,西山伸宏","タンニン酸とフェニルボロン酸導入高分子で構築された自己会合型Cas9 RNP送達システムの開発","第70回高分子討論会",,,,,,2021,Sept. "Yuto Honda,Takahiro Nomoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","Construction of sequential self-assembled protein ternary complex utilizing boronic acid conjugated-polymer and tannic acid for protein delivery","ACS Fall 2021",,,,,,2021,Aug. "Yuto Honda*,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Kaori Taniwaki,Haochen Guo,Yutaka Miura,Nobuhiro Nishiyama*","Systemically Applicable Glutamine-Functionalized Polymer Exerting Multivalent Interaction with Tumors Overexpressing ASCT2.",,"ACS Applied Bio Materials",,"Vol. 4","No. 10","pp. 7402?7407",2021,Aug. "野本貴大,井上透矢,YAOYing,金盛開人,鈴木実,小成田翔,松井誠,西山伸宏","側鎖に糖構造を有する高分子とボロノフェニルアラニンから構成される薬物送達システムの設計","第17回日本中性子捕捉療法学会学術大会",,,,,,2021,July "Yuta Kurashina,Risa Asano,Makoto Matsui,Takahiro Nomoto,Kentaro Nakamura,Nobuhiro Nishiyama,Yoshitaka Kitamoto","Effect of sonophoresis with various nanoparticles on transdermal drug delivery","The 12th International Conference on the Science and Technology for Advanced Ceramics",,,,,,2021,July "本田雄士,野本貴大,松井誠,三浦裕,西山伸宏","タンニン酸とフェニルボロン酸導入高分子の自己会合によって形成されたナノリアクターの酵素プロドラッグ療法への応用","第31回バイオ・高分子シンポジウム",,,,,,2021,June "Guo Haochen,野本貴大,松井誠,河本花奈,ElMuttaqien S.,三浦裕,西山伸宏","高分子鉄キレート剤を用いた腫瘍内鉄イオン制御とそのアスコルビン酸の抗腫瘍効果への影響に関する検討","第37回日本DDS学会学術集会",,,,,,2021,June "野本貴大,小成田翔,鈴木実,松井誠,西山伸宏","ポリビニルアルコールを利用したボロノフェニルアラニンの中性子捕捉療法における治療効果向上","第37回日本DDS学会学術集会",,,,,,2021,June "大橋遼太郎,本田雄士,野本貴大,松井誠,三浦裕,西山伸宏","タンニン酸とフェニルボロン酸導入高分子で構成されるオボアルブミン封入三元系複合体の構築とがん免疫療法への応用","第37回日本DDS学会学術集会",,,,,,2021,June "松尾拓海,本田雄士,野本貴大,松井誠,三浦裕,西山伸宏","タンニン酸とフェニルボロン酸修飾高分子からなるCRISPR/Casタンパク質デリバリーシステムの開発","第37回日本DDS学会学術集会",,,,,,2021,June "本田雄士,福原菜摘,浮田菜央,松井誠,大野哲史,野本貴大,西山伸宏,保科克行,三浦裕","ボロン酸エステルを介したスタチン内包高分子型ミセルの構築および薬理効果","第37回日本DDS学会学術集会",,,,,,2021,June "本田雄士,野本貴大,松井誠,三浦裕,西山伸宏","タンニン酸とフェニルボロン酸導入高分子から成る自己会合型ナノリアクターの構築および酵素プロドラッグ療法への応用","第37回日本DDS学会学術集会",,,,,,2021,June "長尾周平,本田雄士,喜納宏昭,野本貴大,Liu Xueying,Dirisala Anjaneyulu,松井誠,三浦裕,片岡一則,西山伸宏","アデノ随伴ウイルス(AAV)ベクターの中和抗体および副作用を克服するAAV/タンニン酸/ボロン酸導入高分子三元系複合体の構築","第37回日本DDS学会学術集会",,,,,,2021,June "小成田翔,野本貴大,金盛開人,鈴木実,松井誠,三浦裕,西山伸宏","Poly(vinyl alcohol)と D-4-boronophenylalanine から構成される 薬物送達システムによるホウ素中性子捕捉療法の検討","第70回高分子学会年次大会",,,,,,2021,May "Takahiro Nomoto,Ying Yao,Yukiya Inoue,Minoru Suzuki,Kaito Kanamori,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Fructose-functionalized polymers to enhance therapeutic potential of p-boronophenylalanine for neutron capture therapy",,"Journal of Controlled Release",,"Vol. 332",,"pp. 184-193",2021,Feb. "Komoto Kana,Takahiro Nomoto,Muttaqien S.,Takemoto Hiroyasu,Matsui Makoto,Miura Yutaka,Nishiyama Nobuhiro","Iron chelation cancer therapy using hydrophilic block copolymers conjugated with deferoxamine",,"Cancer Science",,"Vol. 112","No. 1","pp. 410-421",2021,Jan. "S Muttaqien,Takahiro Nomoto,Xuebo Dou,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","Photodynamic therapy using LCST polymers exerting pH-responsive isothermal phase transition",,"Journal of Controlled Release",,"Vol. 328",,"pp. 608-616",2020,Dec. "Natsumi Fukuhara,Yuto Honda,Nao Ukita,Makoto Matsui,Yutaka Miura,Katsuyuki Hoshina","Efficient Suppression of Abdominal Aortic Aneurysm Expansion in Rats through Systemic Administration of Statin-Loaded Nanomedicine",,"International Journal of Molecular Sciences",,"Vol. 21","issue 22","p. 8702",2020,Nov. "武元宏泰,野本貴大,松井誠,三浦裕,西山伸宏","高分子修飾によるsiRNA周囲の空間支配と薬理機構制御",,,,,,,2020,Sept. "豊田真広,武元宏泰,野本貴大,松井誠,三浦裕,西山伸宏","腫瘍内pH応答性の獲得を目指した高分子ベタイン内の両イオン性基の種類・間隔の検討",,,,,,,2020,Sept. "SUNYudi,武元宏泰,野本貴大,松井誠,三浦裕,西山伸宏","ASO-分岐PEG結合体を内包する小分子キャリアの開発および機能評価",,,,,,,2020,Sept. "Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Kaito Kanamori,Kakeru Konarita,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","Development of functional polymers to boost therapeutic potential of boronophenylalanine in neutron capture therapy","第69回高分子討論会",,,,,,2020,Sept. "河本花奈,野本貴大,Sjaikhurrizal El Muttaqien,武元宏泰,松井誠,三浦裕,西山伸宏","がん鉄キレート療法のための効率的な除鉄を実現する機能性高分子の開発","第69回高分子討論会",,,,,,2020,Sept. "I Dewa Agung Panji Dwipayana,Yuto Honda,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","Development of a versatile drug delivery system using tannic acid and boronic acid-conjugated polymer","第69回高分子討論会",,,,,,2020,Sept. "ムツタキンシャイクリザルエル,Yutaka Miura,Haochen Guo,Takahiro Nomoto,Kana Komoto,S Muttaqien,Xiaohang Sun,Hiroyasu Takemoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","Polymeric iron-chelators for improving high- dose vitamin C therapy","第69回高分子討論会",,,,,,2020,Sept. "Xiaohang Sun,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Haochen Guo,Yudi Sun,Yutaka Miura,Nobuhiro Nishiyama","Potential urinary monitoring of the enhanced permeability and retention effect using MMP-2-responsive poly(ethylene glycol) derivatives",,"Journal of Controlled Release",,,,,2020,Sept. "Yuto Honda,Takahiro Nomoto,Makoto Matsui,Hiroyasu Takemoto,Yuka Kaihara,Yutaka Miura,Nobuhiro Nishiyama","Sequential Self-Assembly Using Tannic Acid and Phenylboronic Acid-Modified Copolymers for Potential Protein Delivery",,"Biomacromolecules",,"Vol. 21","No. 9","pp. 3826-3835",2020,Sept. "Yuta Kurashina,Risa Asano,Makoto Matsui,Takahiro Nomoto,Kentaro Nakamura,Nobuhiro Nishiyama,Yoshitaka Kitamoto","Transdermal Delivery of Large Nanoparticles via Ultrasonic Irradiation in Low-Frequency Range","2020 International Ultrasonics Symposium(IUS2020)","Proceedings of IUS 2020",,,," C1P-24-1150",2020,Sept. "武元宏泰,稲葉高徳,野本貴大,松井誠,三浦裕,西山伸宏",""環状アセタール構造に基づくゲムシタビン担持型高分子の開発とその機能評価 および副作用低減"","第36回日本DDS学会学術集会",,,,,,2020,Aug. "Guo Haochen,野本貴大,河本花奈,ElMuttaqien S.,Sun Xiaohang,武元宏泰,松井誠,三浦裕,西山伸宏","Effect of polymeric iron-chelators on high-dose vitamin C therapy","第36回日本DDS学会学術集会",,,,,,2020,Aug. "Guo Haochen,Takahiro Nomoto,Kana Komoto,Sun Xiaohang,Hiroyasu Takemoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","Development of polymeric iron-chelators for enhancing high-dose vitamin C therapy","第 3 回 COI 学術交流会",,,,,,2020,July "野本貴大,本田雄士,海原悠可,喜納宏昭,武元宏泰,松井誠,西山伸宏","タンニン酸とボロン酸ケミストリーを利用した高分子複合体の簡便調製法","第 3 回 COI 学術交流会",,,,,,2020,July "Takahiro Nomoto,Sjaikhurrizal El Muttaqien,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","Photodynamic therapy utilizing functional polymers that exert pH-responsive isothermal phase transition","ICPST-36",,,,,,2020,June "武元宏泰,野本貴大,松井誠,三浦裕,西山伸宏",""環状アセタール構造を介したゲムシタビンのポリアミノ酸への導入と薬効増大 および副作用低減"",,,,,,,2020,May "豊田真広,武元 宏泰,野本 貴大,松井 誠,三浦 裕,西山 伸宏","高分子ベタイン内のイオン性基の種類・間隔の制御と腫瘍内pH応答性への展開","第69回高分子学会年次大会",,,,,,2020,May "Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Kaito Kanamori,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Poly(vinyl alcohol) for enhancing therapeutic effects of p-boronophenylalanine in neutron capture therapy","International Symposium on Biomedical Materials for Drug/Gene Delivery",,,,,,2020,Feb. "Yuto Honda,Takahiro NOMOTO,Makoto MATSUI,Hiroyasu TAKEMOTO,Yuka KAIHARA,Yutaka MIURA,Nobuhiro NISHIYAMA","Development of intracellular pH- responsive protein delivery system utilizing boronic acid-conjugated polymer and tannic acid","International Symposium on Biomedical Materials for Drug/Gene Delivery",,,,,,2020,Feb. "Kana Komoto,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Yutaka Miura,Nobuhiro Nishiyama","Iron chelation cancer therapy using functional polymers targeting tumors","International Symposium on Biomedical Materials for Drug/Gene Delivery",,,,,,2020,Feb. "Takahiro Nomoto,Yukiya Inoue,Ying Yao,M Suzuki,Kaito Kanamori,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Poly(vinyl alcohol) boosting therapeutic potential of p-boronophenylalanine in neutron capture therapy by modulating metabolism",,"Science Advances",,"Vol. 6","No. 4",,2020,Jan. "Hiroyasu Takemoto,Takanori Inaba,Takahiro Nomoto,Makoto Matsui,Gyomon Ryu,Masahiro Toyoda,Yuto Honda,Kaori Taniwaki,Naoki Yamada,Junhyun Kim,Keishiro Tomoda,Nobuhiro Nishiyama","Polymeric modification of gemcitabine via cyclic acetal linkage for enhanced anticancer potency with negligible side effects",,"Biomaterials",,"Vol. 235",,,2020, "Takahiro Nomoto,Xuebo Dou,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Photosensitizer delivery to tumor cells and tumor-associated vasculature using functional polymers","7th International ALA and Prophyrin Symposium (IAPS7)",,,,,,2019,Dec. "河本花奈,野本貴大,武元宏泰,松井誠,三浦裕,西山伸宏","がん治療のための効率的な生体内の除鉄を実現する機能性高分子の開発","第41回日本バイオマテリアル学会大会",,,,,,2019,Nov. "武元宏泰,稲葉高徳,野本貴大,松井誠,三浦裕,西山伸宏","環状アセタール構造に基づくゲムシタビンの高分子修飾と制がん効果増大及び副作用低減","第41回日本バイオマテリアル学会大会",,,,,,2019,Nov. "野本貴大,井上透矢,YAOYing,金盛開人,鈴木実,武元宏泰,松井誠,西山伸宏","生体適合性高分子とボロノフェニルアラニンから構成される中性子捕捉療法用代謝制御型ホウ素送達システム","第41回日本バイオマテリアル学会大会",,,,,,2019,Nov. "野本貴大,松井誠,武元宏泰,海原悠可,三浦裕,西山伸宏","ボロン酸導入高分子とタンニン酸を用いた細胞内環境応答タンパク質送達システムの構築","第41回日本バイオマテリアル学会大会",,,,,,2019,Nov. "野本貴大,ElMuttaqien S.,武元宏泰,松井誠,西山伸宏","腫瘍内低pH環境に応答して親水-疎水相転移挙動を示す高分子コンジュゲート型光増感剤","PhotoDynamic Medicine 2019",,,,,,2019,Sept. "Kaito Kanamori,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","BPA delivery system utilizing sugar-modified polymers forming stable boronate esters","The 10th Young Member’s Boron Neutron Capture Therapy (10th YBNCT)","The 10th Young Member’s Boron Neutron Capture Therapy (10th YBNCT)",,,,,2019,Sept. "Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Kaito Kanamori,Makoto Matsui,Hiroyasu Takemoto,Nobuhiro Nishiyama","Boosting Therapeutic Potential of p-Boronophenylalanine Using Biocompatible Polymers","The 10th Young Member’s Boron Neutron Capture Therapy (10th YBNCT)",,,,,,2019,Sept. "本田雄士,山田直生,武元宏泰,野本貴大,松井誠,友田敬士郎,西山伸宏","がん細胞の高密度グルタミントランスポーターと選 択的な相互作用を示す機能性高分子の開発","第68回高分子討論会",,,,,,2019,Sept. "野本貴大,井上透矢,YAOYing,金盛開人,鈴木実,武元宏泰,松井誠,友田敬士郎,西山伸宏","生体適合性高分子とp-boronophenylalanineから構成されるホウ素送達システムの開発と構成高分子の物性が体内動態と治療効果に与える影響に関する考察","第16回日本中性子捕捉療法学会",,,,,,2019,Sept. "武元宏泰,AZIZMUHAMMAD,RannehA-Hackam,野本貴大,松井誠,三浦裕,西山伸宏","腫瘍内pH応答性高分子ベタインの設計と被覆ナノ粒子への展開","第68回高分子討論会",,,,,,2019,Sept. "小野寺彩,武元宏泰,野本貴大,松井誠,三浦裕,西山伸宏","温度応答性高分子-siRNA結合体の合成と外部刺激によるsiRNAの生物活性制御","第68回高分子討論会",,,,,,2019,Sept. "Nobuhiro Nishiyama,Kana Komoto,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui","Development of polymeric iron chelator for cancer therapy","The 3rd Workshop for Japan-Korea Young Scientists on Pharceutics",,,,,,2019,July "武元宏泰,AZIZMUHAMMAD,野本貴大,松井誠,西山伸宏","腫瘍 pH 応答性高分子ベタインの開発とナノ粒子のがん送達への展開","第35回日本DDS学会学術集会",,,,,,2019,July "松井誠,海原悠可,武元宏泰,野本貴大,西山伸宏","薬物送達技術を応用した新規骨折治療法の開発","第35回日本DDS学会学術集会",,,,,,2019,July "金盛開人,野本貴大,鈴木実,武元宏泰,松井誠,西山伸宏","ボロン酸エステルを利用したホウ素薬物送達キャリアの開発","第35回日本DDS学会学術集会",,,,,,2019,July "河本花奈,野本貴大,武元宏泰,松井誠,西山伸宏","がん治療を指向した生体内鉄イオンをキレートする機能性高分子の開発","第35回日本DDS学会学術集会",,,,,,2019,July "小野寺彩,武元宏泰,野本貴大,友田敬士郎,松井誠,西山伸宏","温度応答性高分子-siRNA結合体とのポリイオンコンプレックス形成と外部刺激によるsiRNA の薬効制御",,,,,,,2019,July "本田雄士,山田直生,武元宏泰,野本貴大,松井誠,友田敬士郎,西山伸宏","がん細胞の高密度グルタミントランスポーターを標的として選択的な相互作用を示す機能性高分子の開発","第68回高分子学会年次大会",,,,,,2019,May "豊田真広,武元宏泰,野本貴大,松井誠,西山伸宏","腫瘍内pH応答性高分子ベタイン内のイオン性基間距離の検討","第68回高分子学会年次大会",,,,,,2019,May "小野寺彩,武元宏泰,野本貴大,友田敬士郎,松井誠,西山伸宏","ポリイオンコンプレックスを利用した温度応答性高分子-siRNA結合体の細胞内導入と外部刺激によるsiRNAの生物活性制御","第68回高分子学会年次大会",,,,,,2019,May "金盛開人,野本貴大,鈴木実,武元宏泰,松井誠,西山伸宏","糖修飾高分子とホウ素薬物から構成される薬物送達システムの開発","第68回高分子学会年次大会",,,,,,2019,May "野本貴大,井上透矢,YAOYing,鈴木実,金盛開人,武元宏泰,松井誠,友田敬士郎,西山伸宏","Metabolism-controlled boron delivery systems composed of biocompatible polymers and boronophenylalanine for neutron capture therapy",,"Abstracts of Papers of the American Chemical Society",,,,,2019, "Kaito Kanamori,Takahiro Nomoto,Minoru Suzuki,Hiroyasu Takemoto,Makoto Matsui,Nobuhiro Nishiyama","Boron Delivery Using Sugar-Modified Polymers for Neutron Capture Therapy","The 3rd Workshop for Japan-Korea Young Scientists on Pharceutics",,,,,,2019, "Sun Xiaohang,Taknaori Inaba,Kazuki Ohsakama,Mika Shishido,Hiroki Yoshioka,武元宏泰,野本貴大,松井誠,友田敬士郎,西山伸宏","Development of degradable poly(ethylene glycol)(PEG) derivatives for suppressing cellular vacuolations","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec. "Muttaqien,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Poly(N-isopropylacrylamide)-based polymer inducing isothermal hydrophilic-to-hydrophobic phase transition via detachment of hydrophilic acid-labile moiety",,"BIOMACROMOLECULES",,"Vol. 20","No. 4","pp. 1493-1504",2018,Dec. "Yuto Honda,Naoki Yamada,Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Kaito Kanamori,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Tumor cell-targeting glutamine-derived polymer that can interact with high density glutamine transporter based on aberrant glutamine metabolism.","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec. "Yuka Kaihara,Makoto Matsui,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Nobuhiro Nishiyama","Development of novel drug delivery system for enhancing bone regeneration in bone fracture model mouse","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec. "Sayaka Onodera,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","Conjugation of siRNA and a polymer with coil-globule transition property for control of siRNA activity around body temperature","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec. "Gyomon Ryu,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Development of poly(amino acid)-based carrier that loads gemcitabine via reversible linkage and its evaluation using pancreatic cancer model","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec. "Hiroyasu Takemoto,Abdul-Hackam Ranneh,Takahiro Nomoto,Makoto Matsui,Nobuhiro Nishiyama","Ethylenediamine-based polyzwitterion that becomes cationic at tumorous pH for effective tumor accumulation of the coated nanomaterials","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec. "Sjaikhurrizal El Muttaqien,松井 誠,武元 宏泰,野本 貴 大,友田 敬士郎,西山 伸宏","Poly(N-isopropylacrylamide) derivatives exering remarkable LCST shift in response to slight pH chnge via detachment of hydrophilic acid-labile moiety","The 12th SPSJ International Polymer Conference (IPC2018)",,,,,,2018,Dec. "Fukuba S,Akizuki T,Hoshi S,Matsuura T,Shujaa Addin A,Okada M,Tabata Y,Matsui M,Tabata MJ,Sugiura-Nakazato M,Izumi Y.","Comparison between different isoelectric points of biodegradable gelatin sponges incorporating β-tricalcium phosphate and recombinant human fibroblast growth factor-2 for ridge augmentation: A preclinical study of saddle-type defects in dogs",,"J Periodontal Res",,,,,2018,Nov. "Ying Yao,Takahiro Nomoto,Yukiya Inoue,Minoru Suzuki,Makoto Matsui,Hiroyasu Takemoto,Keishiro Tomoda,Nobuhiro Nishiyama","Enhanced tumor-targeted delivery of p-boronophenylalanine using fructose-functionalized polymers for boron neutron capture therapy","18th International Congress on Neutron Capture Therapy",,,,,,2018,Oct. "Takahiro Nomoto,Yukiya Inoue,Ying Yao,Minoru Suzuki,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Metabolism-controlled boron delivery systems composed of p-boronophenylalanine and poly(vinyl alcohol)","18th International Congress on Neutron Capture Therapy",,,,,,2018,Oct. "Takahiro Nomoto,Xuebo Dou,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Multiple cyclic RGD-conjugated functional polymers controlling intratumoral distribution of IRDye 700DX","Photodynamic Therapy and Photodiagnosis Update 2018",,,,,,2018,Sept. "本田雄士,山田 直生,武元 宏泰,野本 貴 大,松井 誠,友田 敬士郎,西山 伸宏","グルタミン代謝が亢進したがん細胞の高密度グルタ ミントランスポーターを認識してアフィニティを示す機能性高 分子","第67回高分子討論会",,,,,,2018,Sept. "野本 貴大,井上 透矢,Yao Ying,鈴木 実,金盛 開人,武元 宏泰,松井 誠,友田 敬士郎,西山 伸宏","生体適合性機能性高分子によるボロノフェニルアラニンの代謝制御と治療効果の向上","第15回日本中性子捕捉療法学会学術大会",,,,,,2018,Sept. "Gyomon Ryu,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Development of gemcitabine-conjugated poly(amino acid) and its evaluation using pancreatic tumor model","第67回高分子討論会",,,,,,2018,Sept. "Hiroyasu Takemoto,Abduhl Hackam Ranneh,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Ethylenediamine-based betaine structure switches the neutral net charge of polyzwitterion into cationic at tumorous pH toward effective tumor accumulation of the coated nanomaterials","256th ACS National Meeting & Exposition",,,,,,2018,Aug. "Sjaikhurrizal El Muttaqien,Takahiro Nomoto,Hiroyasu Takemoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Novel design of pH-responsive polymer for targeting acidic microenvironment of tumor","256th ACS National Meeting & Exposition",,,,,,2018,Aug. "yao ying,野本貴大,井上透矢,鈴木実,松井誠,武元宏泰,友田敬士郎,西山伸宏","Tumor-targeted delivery of BPA using functional polymers for boron neutron capture therapy","第34回日本DDS学会学術集会",,,,,,2018,June "野本貴大,Dou Xuebo,武元宏泰,松井誠,友田敬士郎,西山伸宏","IRDye 700DXの腫瘍内分布を制御する環状RGD担持高分子コンジュゲートによる光線力学効果の検討","第34回日本DDS学会学術集会",,,,,,2018,June "小野寺彩,武元宏泰,野本貴大,友田敬士郎,松井誠,西山伸宏","siRNAへのCoil-globule挙動を有する高分子の結合と生体温度付近での遺伝子発現抑制能の精密制御","第67回高分子年次大会",,,,,,2018,May "劉暁夢,武元宏泰,野本貴大,松井誠,友田敬士郎,西山伸宏","可逆的にゲムシタビンを担持するポリアミノ酸型キャリアの開発とすい臓がんモデルでの機能評価","第67回高分子年次大会",,,,,,2018,May "X. Dou,T. Nomoto,H. Takemoto,M. Matsui,K. Tomoda,N. Nishiyama","Effect of multiple cyclic RGD peptides on tumor accumulation and intratumoral distribution of IRDye 700DX-conjugated polymers",,"Scientific Reports",,"Vol. 8","No. 1","pp. 8126",2018,May "武元宏泰,Ranneh Abdul-Hackam,野本貴大,松井誠,友田敬士郎,持田祐希,内藤瑞,西山伸宏","腫瘍内環境を認識する高分子ベタインの開発とナノ粒子の効率的な腫瘍集積への展開","第67回高分子年次大会",,,,,,2018,May "A.-H. Ranneh,H. Takemoto,S. Sakuma,A. Awaad,T. Nomoto,Y. Mochida,M. Matsui,K. Tomoda,M. Naito,N. Nishiyama","An ethylenediamine-based switch to control the polyzwitterion charge at tumorous pH for effective tumor accumulation of coated nanomaterials",,"Angewandte Chemie International Edition",,"Vol. 57","No. 18","pp. 5057",2018,Apr. "Naoki Yamada,Yuto Honda,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Glutamine-Functionalized Polymer for Tumor-Selective High Affinity by Sensing Dense Glutamine Transporters Associated with Aberrant Metabolism","14th US-JAPAN Symposium on Drug Delivery Systems",,,,,,2017,Dec. "Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","2-nitrobenzenesulfonamide group that allows highly selective cleavage in intracellular redox system and the application for a construction of siRNA-polymer conjugate","14th US-JAPAN Symposium on Drug Delivery Systems",,,,,,2017,Dec. "山田直生,本田雄士,武元宏泰,野本貴大,松井 誠,友田敬士郎,西山伸宏","がん選択的に相互作用するグルタミン担持高分子の創製と機能評価","第39回日本バイオマテリアル学会大会",,,,,,2017,Nov. "真貝 太規,山田直生,武元宏泰,野本貴大,松井誠,友田敬士郎,西山伸宏","がん代謝に着想した表層にグルタミンを有する高分子ミセル型薬物送達システムの開発","第66回高分子討論会",,,,,,2017,Sept. "武元宏泰,稲葉 高徳,野本 貴大,松井 誠,友田 敬士郎,西山 伸宏","糖骨格を有する制がん剤のポリアミノ酸への可逆的担持と薬効向上及び消化器毒性低減","第66回高分子討論会",,,,,,2017,Sept. "Dou Xuebo,野本 貴大,武元 宏泰,松井 誠,友田 敬士郎,西山 伸宏","光増感剤結合型高分子における多岐環状RGDペプチドの腫瘍集積性と腫瘍内分布への効果の検討","第66回高分子討論会",,,,,,2017,Sept. "左久間隼矢,Abdul-Hackam RANNEH,武元宏泰,野本貴大,松井誠,友田敬士郎,西山伸宏","腫瘍指向性ステルス高分子の開発とDDSへの応 用-ベタイン構造内アニオン性基の影響-","第66回高分子討論会",,,,,,2017,Sept. "武元 宏泰,稲葉 高徳,野本 貴大,松井 誠,友田 敬士郎,西山 伸宏","ゲムシタビンのポリアミノ酸への可逆的担持に基づく消化器毒性低減及び制がん効果向上","第33回日本DDS学会学術集会",,,,,,2017,July "西山 伸広,松井誠","革新的オリゴ核酸送達システムの実現に向けた材料設計","第33回日本DDS学会学術集会",,,,,,2017,July "N. Yamada,Y. Honda,H. Takemoto,T. Nomoto,M. Matsui,K. Tomoda,M. Konno,H. Ishii,M. Mori,N. Nishiyama","Engineering tumour cell-binding synthetic polymers with sensing dense transporters associated with aberrant glutamine metabolism",,"Scientific Reports",,"Vol. 7","No. 1","pp. 6077",2017,July "Hiroyasu Takemoto,Huang Chih-Hao,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","2-Nitrobenzenesulfonamide Group that Responds to Intracellular Redox Potential with Enhanced Photostability for a Construction of Polymer-siRNA Conjugate System","The 34th International Conference of Photopolymer Science and Technology (ICPST-34)",,,,,,2017,June "松井 誠","再生医療・細胞医療に用いる生物由来材料の有用性と安全性について","サイトカイン療法勉強会",,,,,,2017,June "Naoki Yamada,Yuto Honda,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Design of synthetic polymer toward achieving a selective high affinity to tumor cells by interacting with dense glutaminolysis-related transporters","第66回高分子年次大会",,,,,,2017,May "Hiroyasu Takemoto,Chih Hao Huang,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","2-nitrobenzenesulfonamide group as a redox-sensitive linker for a construction of polymer-siRNA conjugate system","第66回高分子年次大会",,,,,,2017,May "左久間隼矢,RannehA-Hackam,武元宏泰,野本貴大,松井誠,友田敬士郎,西山伸宏","腫瘍内pHに応答する双性イオン型ポリマーの設計とDDS応用-ベタイン内アニオン性基の影響-","第66回高分子年次大会",,,,,,2017,May "劉暁夢,武元宏泰,野本貴大,松井誠,友田敬士郎,西山伸宏","ミトコンドリア呼吸鎖阻害剤を腫瘍組織に送達するための高分子ミセルの開発","第66回高分子年次大会",,,,,,2017,May "真貝太規,山田直生,武元宏泰,野本貴大,松井誠,友田敬士郎,西山伸宏","がん特異的代謝に着想した外殻にグルタミンを有する高分子ミセルの開発","第66回高分子年次大会",,,,,,2017,May "Hiroyasu Takemoto,Huang Chih-Hao,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","2-Nitrobenzenesulfonamide group as a chemical linker with highly selective cleavability in response to intracellular redox system for a construction of siRNA-polymer conjugate.","253rd American Chemical Society National Meeting & Exposition",,,,,,2017,Apr. "Yuto Honda,Naoki Yamada,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Novel design of glutamine-derived polymer with a high affinity to cancer cells based on aberrant glutamine metabolism.","253rd American Chemical Society National Meeting & Exposition",,,,,,2017,Apr. "Takanori Inaba,Hiroyasu Takemoto,Makoto Matsui,Takahiro Nomoto,Keishiro Tomoda,Nobuhiro Nishiyama","Enhanced antitumor activity and reduced gastrointestinal toxicity of gemcitabine based on conjugation with biocompatible polymer via acetal linker","International Symposium on Drug Delivery and Pharmaceutical Sciences: Beyond the History (ISDDPS)",,,,,,2017,Mar. "Ranneh Hackam,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Development of stealth shell based on polycarboxybetaine structure tuned to selectively interact with cells in tumor extracellular acidic pH","日本薬学会第137年会",,,,,,2017,Mar. "?Tsukasa Nishimori,Naoki Yamada,Hiroyasu Takemoto,Kentaro Suina,Juntaro Yamasaki,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Osamu Nagano,Hideyuki Saya,Nobuhiro Nishiyama","Development of intravenously injectable sulfasalazine derivatives to treat stem-like cancer cells","International Symposium on Drug Delivery and Pharmaceutical Sciences: Beyond the History (ISDDPS)",,,,,,2017,Mar. "Chi-Hao Huang,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","2-nitrobenzenesulfonamide group as a new chemical linker with redox sensitivity for siRNA-conjugated polymer system","11th Annual Symposium on Nanobiotechnology 2017",,,,,,2017,Feb. "Chih-Hao Huang,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","Utility of 2-Nitrobenzenesulfonamide Group as a Chemical Linker for Enhanced Extracellular Stability and Cytosolic Cleavage in siRNA-conjugated Polymer System",,"ChemMedChem",,"Vol. 12","No. 1","pp. 19-22",2017,Jan. "松井 誠","薬物徐放性基材(DDS)としての安全性と徐放評価 -複数の生理活性物質の徐放技術とその徐放性評価-",,"生体吸収性材料の開発と安全性評価",,,,,2017, "Faizah Noor,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","Artificial control of siRNA bioactivity based on the phase transition behavior of the conjugated polymeric molecule","The 11th SPSJ International Polymer Conference (IPC2016)",,,,,,2016,Dec. "Chihhao Huang,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","2-nitrobenzensulfonamide groups as a chemical linker with enhanced extracellular stability and redox-sensitive cleavability for siRNA-conjugated polymer system","The 11th SPSJ International Polymer Conference (IPC2016)",,,,,,2016,Dec. "Naoki Yamada,Yuto Honda,Hiroyasu Takemoto,Takahiro Nomoto,Makoto Matsui,Keishiro Tomoda,Nobuhiro Nishiyama","Novel glutamine-based polymeric ligand for transporter-mediated tumor targeting","3rd International Conference on Biomaterials Science in Tokyo",,,,,,2016,Nov. "KimJunhyun,武元 宏 泰,野本 貴大,松井 誠,友田 敬士郎,西山 伸宏","高分子ミセルにおける内核構造の安定性の差異がもたらす腫瘍集積性に関する考察","第65回高分子討論会",,,,,,2016,Sept. "SunXiaohang,武元 宏 泰,野本 貴大,友田 敬士郎,松井 誠,西山 伸宏","がんへの薬剤の集積状態をレポートするナノメディシンの開 発","第65回高分子討論会",,,,,,2016,Sept. "Chih Ling Wang,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","A Novel Design of Polyion Complex (PIC) with The Pyruvate-Reactive Function toward Enhanced Cytosolic Release of siRNA","第65回高分子討論会",,,,,,2016,Sept. "Faizah Noor,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","Development of siRNA-conjugated polymer with coil-globule transition behavior for an artificially controlled gene silencing activity","第65回高分子討論会",,,,,,2016,Sept. "Faizah Noor,Hiroyasu Takemoto,Takahiro Nomoto,Keishiro Tomoda,Makoto Matsui,Nobuhiro Nishiyama","Artificial Control of Gene Silencing Activity Based on siRNA Conjugation with Polymeric Molecule Having Coil?Globule Transition Behavior",,"Bioconjugate Chemistry",,,,,2016,Aug. "Makoto Matsui","Gelatin hydrogel impregnated with platelet-rich plasma releasate promotes angiogenesis and wound healing in murine model",,"J Artif Organs",,"Vol. 18","No. 1","pp. 64-71",2015, "松井 誠,田畑 泰彦","細胞3次元組織化のための材料「複合材料」",,"遺伝子医学MOOK別冊「細胞の3次元組織化に不可欠な最先端材料技術」",,,,"pp. 99-104",2014, "M Matsui,M Yamamoto,Y Tabata","Platelet-rich plasma enhances angiogenesis induced by basic fibroblast growth factor from release gelatin hydrogels","The 13th US ? Japan Symposium on Drug Delivery System",,,,,,2013,Dec. "M Matsui,M Yamamoto,Y Tabata","Enhanced angiogenesis by multiple release of platelet-rich plasma (PRP) components and basic fibroblast growth factor (bFGF) from gelatin hydrogels",,,,,,,2013,Oct. "M Matsui,M Yamamoto,Y Tabata","Enhanced angiogenesis by multiple release of platelet-rich plasma components and basic fibroblast growth factor from gelatin hydrogels","The 4th Asian Biomaterials Congress",,,,,,2013,Sept. "松井 誠,田畑 泰彦","骨欠損に対する多血小板血漿を用いた再生治療法の開発",,"整形・災害外科「再生医療の現状と最前線」",,"Vol. 56","No. 5","pp. 635-42",2013, "松井 誠,田畑 泰彦","生理活性物質 -Dual release-",,"遺伝子医学MOOK別冊「ここまで広がるドラッグ徐放技術の最前線」",,,,,2013, "Nakanishi H,Kodera Y,Hara K,Yokoyama H,Matsui M,Tatematsu M,Ikehara Y","HER signaling as multiple therapeutic targets in gastric and gastroesophageal junction cancers. (Review), Targeted Proteins database (TPdb).",,"Current Biodata Ltd., Online Journal",,,,,2008,