"Junichi Yamamoto,Tomoko Asatsuma-Okumura,Takumi Ito,Yuki Yamaguchi,Hiroshi Handa","History of IMiDs and Protein Degradation as a Pharmacological Modality",,"Protein Homeostasis in Drug Discovery: A Chemical Biology Perspective","John Wiley & Sons",,,,2022,Nov. "Junichi Yamamoto,Takumi Ito,Yuki Yamaguchi,Hiroshi Handa","Discovery of CRBN as a target of thalidomide: a breakthrough for progress in the development of protein degraders.",,"CHEM. SOC. REV.",," 51",," 6234-6250",2022,July "Nobuyuki Shimizu,Tomoko Asatsuma-Okumura,Junichi Yamamoto,Yuki Yamaguchi,Hiroshi Handa,Takumi Ito","PLZF and its fusion proteins are pomalidomide-dependent CRBN neosubstrates",,"Commun. Biol.",," 4"," 1"," 1277",2021,Nov. "Takumi Ito,Yuki Yamaguchi,Hiroshi Handa","Exploiting ubiquitin ligase cereblon as a target for small-molecule compounds in medicine and chemical biology",,"Cell Chem. Biol.",," 28"," 7"," 987-999",2021,July "Junichi Yamamoto,Tetsufumi Suwa,Yuki Murase,Shunpei Tateno,Hirotaka Mizutome,Tomoko Asatsuma-Okumura,Nobuyuki Shimizu,Tsutomu Kishi,Shuji Momose,Masahiro Kizaki,Takumi Ito,Yuki Yamaguchi,Hiroshi Handa","ARID2 is a pomalidomide-dependent CRL4CRBN substrate in multiple myeloma cells",,"Nature Chemical Biology",,,,,2020,Sept. "Shunpei Tateno,Midori Iida,Satoshi Fujii,Miki Katayama,Haruka Tokuyama,Junichi Yamamoto,Takumi Ito,Satoshi Sakamoto,Hiroshi Handa,Yuki Yamaguchi","Genome-wide screening reveals a role for subcellular localization of CRBN in the anti-myeloma activity of pomalidomide?",,"Scientific Reports",,"Volume 10","Number 4012",,2020,Mar. "Asatsuma-Okumura T,Ando H,De Simone M,Yamamoto J,Sato T,Shimizu N,Asakawa K,Yamaguchi Y,Takumi Ito,Guerrini L,Hiroshi Handa","p63 is a cereblon substrate involved in thalidomide teratogenicity",,"Nature Chemical Biology",,," 15","Page 1077?1084",2019,Oct. "ŽRŒϋ —Y‹P,ˆΙ“‘‘ρ…,ŽR–{~ˆκ,”Ό“cG","ƒTƒŠƒhƒ}ƒCƒh‚Μ‘½—l‚Θ–ς—μ—p‚Μ•ͺŽqƒƒJƒjƒYƒ€","VŠwp—ΜˆζŒ€‹†u“]ŽΚƒTƒCƒNƒ‹v“~‚ΜŽαŽθƒ[ƒNƒVƒ‡ƒbƒv2016",,,,,,2016,Feb. "•ΠŽR ”όŽχ,ˆΙ“‘‘ρ…,ˆΐ“‘ GŽχ,ŽRŒϋ —Y‹P,”Ό“cG","E3ƒ†ƒrƒLƒ`ƒ“ƒŠƒK[ƒ[‚ΜŠξŽΏ”FŽ―ƒŒƒZƒvƒ^[ CRBN‚Ζƒ|ƒ}ƒŠƒhƒ}ƒCƒhˆΛ‘Ά“I‚ΘŠξŽΏAiolos‚̐Ά‰»Šw“I‰πΝ","‘ζ‚R‚V‰ρ“ϊ–{•ͺŽqΆ•¨Šw‰ο”N‰ο",,,,,,2014,Nov.