@article{CTT100899661,
  author = {Haruka Kono and Satoshi Hara and Tadaomi Furuta and Hiroshi Ichinose},
  title = {Binding profile of quinonoid-dihydrobiopterin to quinonoid-dihydropteridine reductase examined by in silico and in vitro analyses},
  journal = {J Biochem},
  year = 2023,
}

@article{CTT100917358,
  author = {Tschaffon-Muller MEA and Kempter E and Steppe L and Kupfer S and Kuhn MR and Gebhard F and Pankratz C and Kalbitz M and Schutze K and Gundel H and Kaleck N and Strauss G and Vacher J and Ichinose H and Weimer K and Ignatius A and Haffner-Luntzer M and Reber SO},
  title = {Neutrophil-derived catecholamines mediate negative stress effects on bone},
  journal = {Nature Communications},
  year = 2023,
}

@article{CTT100917357,
  author = {Yuka Nago-Iwashita and Moriya Y and Hara S and Ogawa R and Aida R and Miyajima K and Shimura T and Muramatsu SI and Ide S and Ikeda K and Ichinose H},
  title = {Overexpression of tyrosine hydroxylase in dopaminergic neurons increased sensitivity to methamphetamine},
  journal = {Neurochemistry International},
  year = 2023,
}

@article{CTT100895507,
  author = {Suganuma Y and Sumi-Ichinose C and Kano T and Ikemoto K and Matsui T and Ichinose H and Kondo K},
  title = {Quinonoid dihydropteridine reductase, a tetrahydrobiopterin-recycling enzyme, contributes to 5-hydroxytryptamine-associated platelet aggregation in mice},
  journal = {Journal of Pharmacological Sciences},
  year = 2022,
}

@article{CTT100895508,
  author = {Madokoro Y and Kamikokuryo C and Niiyama S and Ito T and Hara S and Ichinose H and Kakihana Y},
  title = {Early ascorbic acid administration prevents vascular endothelial cell damage in septic mice},
  journal = {Front Pharmacol},
  year = 2022,
}

@article{CTT100895509,
  author = {Kuhn MR and Haffner-Luntzer M and Kempter E and Reber SO and Ichinose H and Vacher J and Ignatius A and Tschaffon-Muller MEA},
  title = {Myeloid cell-derived catecholamines influence bone turnover and regeneration in mice},
  journal = {Front Endocrinol (Lausanne)},
  year = 2022,
}

@article{CTT100879502,
  author = {C. Sumi-Ichinose and Y. Suganuma and T. Kano and K. Ikemoto and N. Ihira and H. Ichinose and K. Kondo},
  title = {Priapism caused by partial deficiency of tetrahydrobiopterin through hypofunction of the sympathetic neurons in sepiapterin reductase gene-disrupted mice},
  journal = {J INHERIT METAB DIS},
  year = 2022,
}

@article{CTT100879322,
  author = {Hara S and Sanatani T and Tachikawa N and Yoshimura Y and Miyata N and Sasaki H and Kuroda R and Kamikokuryo C and Eguchi T and Niiyama S and Kakihana Y and Ichinose H.},
  title = {Comparison of the levels of neopterin, CRP, and IL-6 in patients infected with and without SARS-CoV-2.},
  journal = {Heliyon},
  year = 2022,
}

@article{CTT100879330,
  author = {Miyajima K and Sudo Y and Sanechika S and Hara Y and Horiguchi M and Xu F and Suzuki M and Hara S and Tanda K and Inoue KI and Takada M and Yoshioka N and Takebayashi H and Mori-Kojima M and Sugimoto M and Sumi-Ichinose C and Kondo K and Takao K and Miyakawa T and Ichinose H.},
  title = {Perturbation of monoamine metabolism and enhanced fear responses in mice defective in the regeneration of tetrahydrobiopterin},
  journal = {Journal of neurochemistry},
  year = 2022,
}

@article{CTT100895505,
  author = {Sumi-Ichinose C and Suganuma Y and Kano T and Ikemoto K and Ihira N and Ichinose H and Kondo K},
  title = {Priapism caused by partial deficiency of tetrahydrobiopterin through hypofunction of the sympathetic neurons in sepiapterin reductase gene-disrupted mice},
  journal = {J Inherit Metab Dis},
  year = 2022,
}

@article{CTT100879331,
  author = {Inukai S and Hara S and Ichinose H.},
  title = {Tyrosine hydroxylase activity is regulated through the modification of the 176th cysteine residue},
  journal = {Biochem Biophys Res Commun.},
  year = 2022,
}

@article{CTT100856882,
  author = {Miyajima K and Kawamoto C and Hara S and Mori-Kojima M and Ohye T and Sumi-Ichinose C and Saito N and Sasaoka T and Metzger D and Ichinose H},
  title = {Tyrosine hydroxylase conditional knockout mice reveal peripheral tissue-dependent differences in dopamine biosynthetic pathways},
  journal = {},
  year = 2021,
}

@article{CTT100856881,
  author = {Yang P and Tian H and Zou YR and Chambon P and Ichinose H and Honig G and Diamond B and Kim SJ},
  title = {Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis},
  journal = {},
  year = 2021,
}

@article{CTT100856880,
  author = {Kawai F and Ohkuma M and Horiguchi M and Ichinose H and Miyachi E.I.},
  title = {A subset of cone bipolar cells expresses the Na(+) channel SCN2A in the human retina},
  journal = {Experimental Eye Research},
  year = 2021,
}

@article{CTT100832289,
  author = {hirokazu arai and rina takahashi and yoshiaki sakamoto and tatsuya kitano and okishi mashita and satoshi hara and satoru yoshikawa and koh kawasaki and hiroshi ichinose},
  title = {Peripheral tetrahydrobiopterin is involved in the pathogenesis of mechanical hypersensitivity in a rodent postsurgical pain model},
  journal = {Pain},
  year = 2020,
}

@article{CTT100819686,
  author = {Zhang L and Hara S and Ichinose H and Nagashima D and Morita K and Sakurai T and Ichihara S and Ichihara G.},
  title = {Exposure to acrylamide decreases noradrenergic axons in rat brain.},
  journal = {NEUROTOXICOLOGY},
  year = 2020,
}

@article{CTT100813612,
  author = {Takeshita N and Kawade N and Suzuki W and Hara S and Horio F and Ichinose H},
  title = {Deficiency of ascorbic acid decreases the contents of tetrahydrobiopterin in the liver and the brain of ODS rats.},
  journal = {Neuroscience letters},
  year = 2020,
}

@article{CTT100811103,
  author = {Miramontes-Gonzalez JP and Hightower M and Zhang K and Kurosaki H and Schork AJ and Biswas N and Vaingankar S and Mahata M and Lipkowitz MS and Nievergelt CM and Baker DG and Ziegler MG and Leon-Jimenez D and Gonzalez-Sarmiento R and Ichinose H and O'Connor DT},
  title = {A new common functional coding variant at the DDC gene change renal enzyme activity and modify renal dopamine function.},
  journal = {Scientific Reports},
  year = 2019,
}

@article{CTT100783839,
  author = {Hara S and Fukumura S and Ichinose H},
  title = {Reversible S-glutathionylation of human 6-pyruvoyl tetrahydropterin synthase protects its enzymatic activity},
  journal = {Journal of Biological Chemistry},
  year = 2019,
}

@article{CTT100811101,
  author = {Jin F and Li X and Deng Y and Timilshina M and Huang B and Kim DY and Chang JH and Ichinose H and Baek SH and Murakami M and Lee YJ and Chang HW},
  title = {The orphan nuclear receptor NR4A1 promotes FcepsilonRI-stimulated mast cell activation and anaphylaxis by counteracting the inhibitory LKB1/AMPK axis.},
  journal = {Allergy},
  year = 2018,
}

@article{CTT100777986,
  author = {宮嶋克也 and 原怜 and 一瀬宏},
  title = {葉酸代謝はオリゴデンドロサイトの分化や生存を制御している},
  journal = {},
  year = 2018,
}

@article{CTT100811100,
  author = {Tel-Karthaus N and Kers-Rebel ED and Looman MW and Ichinose H and de Vries CJ and Ansems M},
  title = {Nuclear Receptor Nur77 Deficiency Alters Dendritic Cell Function.},
  journal = {Frontiers in Immunology},
  year = 2018,
}

@article{CTT100811099,
  author = {Toshiharu Nagatsu and Akira Nakashima and Hiroshi Ichinose and Kazuto Kobayashi},
  title = {Human tyrosine hydroxylase in Parkinson's disease and in related disorders.},
  journal = {J Neural Transm},
  year = 2018,
}

@article{CTT100753579,
  author = {Hiroshi Ichinose and Ken-ichi Inoue and Shinobu Arakawa and Yuki Watanabe and Hiroki Kurosaki and Shoko Koshiba and Eldbjorg Hustad and Masahiko Takada and Jan O. Aasly},
  title = {Alterations in the reduced pteridine contents in the cerebrospinal fluids of LRRK2 mutation carriers and patients with Parkinson's disease.},
  journal = {Journal of neural transmission},
  year = 2017,
}

@article{CTT100753580,
  author = {Motokazu Koga and Anna Sezaki and Yuka Nakao and Yuji Kamikubo and Tatsuo Hashimoto and Yuki Okuyama-Oki and Aderemi Caleb Aladeokin and Fumio Nakamura and Utako Yokoyama and Hiromichi Wakui and Hiroshi Ichinose and Takashi Sakurai and Satoshi Umemura and Koichi Tamura and Yoshihiro Ishikawa and Yoshio Goshima},
  title = {L-DOPA sensitizes vasomotor tone by modulating the vascular alpha1-adrenergic receptor.},
  journal = {JCI insight},
  year = 2017,
}

@article{CTT100777985,
  author = {竹下直輝 and 原怜 and 一瀬宏},
  title = {キサンツレン酸はビオプテリン生合成酵素の阻害作用を持つ},
  journal = {ビタミン},
  year = 2017,
}

@article{CTT100753581,
  author = {Tobias Rothe and Natacha Ipseiz and Maria Faas and Stefanie Lang and Francesc Perez-Branguli and Daniel Metzger and Hiroshi Ichinose and Beate Winner and Georg Schett and Gerhard Krönke},
  title = {The Nuclear Receptor Nr4a1 Acts as a Microglia Rheostat and Serves as a Therapeutic Target in Autoimmune-Driven Central Nervous System Inflammation},
  journal = {The Journal of Immunology},
  year = 2017,
}

@article{CTT100753582,
  author = {Chiho Sumi-Ichinose and Yui Suganuma and Taiki Kano and Noriko Ihira and Hiroko Nomura and Kazuhisa Ikemoto and Tadayoshi Hata and Setsuko Katoh and Hiroshi Ichinose and Kazunao Kondo},
  title = {Sepiapterin reductase gene-disrupted mice suffer from hypertension with fluctuation and bradycardia.},
  journal = {Physiological reports},
  year = 2017,
}

@article{CTT100753577,
  author = {Keiko Imamura and Takayuki Kondo and Yasushi Koshiba and Satoshi Hara and Hiroshi Ichinose and Mahoko Furujo and Masako Kinoshita and Tomoko Oeda and Jun Takahashi and Ryosuke Takahashi and Haruhisa Inoue},
  title = {Genetic and pharmacological correction of aberrant dopamine synthesis using patient iPSCs with BH4 metabolism disorders.},
  journal = {Human Molecular Genetics},
  year = 2016,
}

@article{CTT100718630,
  author = {加藤北都 and 原怜 and 一瀬宏},
  title = {パーキンソン病動物モデルにおけるイソチオシアネートの神経保護作用について},
  journal = {ビタミン},
  year = 2016,
}

@article{CTT100753578,
  author = {Hiroshi Ichinose},
  title = {Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice.},
  journal = {Journal of Inherited Metabolic Disease},
  year = 2016,
}

@article{CTT100706717,
  author = {Hanna RN and Cekic C and Sag D and Tacke R and Thomas GD and Nowyhed H and Herrley E and Rasquinha N and McArdle S and Wu R and Peluso E and Metzger D and Ichinose H and Shaked I and Chodaczek G and Biswas SK and Hedrick CC},
  title = {Patrolling monocytes control tumor metastasis to the lung.},
  journal = {Science},
  year = 2015,
}

@article{CTT100706770,
  author = {Ichiro Kawahata and Shiori Ohtaku and Yoshihisa Tomioka and Hiroshi Ichinose and Tohru Yamakuni},
  title = {Dopamine or biopterin deficiency potentiates phosphorylation at (40)Ser and ubiquitination of tyrosine hydroxylase to be degraded by the ubiquitin proteasome system},
  journal = {Biochem Biophys Res Commun},
  year = 2015,
}

@article{CTT100706842,
  author = {Sekiya T and Kondo T and Shichita T and Morita R and Ichinose H and Yoshimura A},
  title = {Suppression of Th2 and Tfh immune reactions by Nr4a receptors in mature T reg cells.},
  journal = {J. Exp. Med.},
  year = 2015,
}

@article{CTT100753576,
  author = {Sugiura K and Nagai T and Nakano M and Ichinose H and Nakabayashi T and Ohta N and Hisabori T},
  title = {Redox sensor proteins for highly sensitive direct imaging of intracellular redox state.},
  journal = {Biochem. Biophys. Res. Commun.},
  year = 2015,
}

@article{CTT100676744,
  author = {Feng Xu and Yusuke Sudo and Sho Sanechika and Junpei Yamashita and Sho Shimaguchi and Shun-ichiro Honda and Chiho Sumi-Ichinose and Masayo Mori-Kojima and Rieko Nakata and Tadaomi Furuta and Minoru Sakurai and Masahiro Sugimoto and Tomoyoshi Soga and Kazunao Kondo and Hiroshi Ichinose},
  title = {Disturbed biopterin and folate metabolism in the Qdpr-deficient mouse},
  journal = {FEBS Lett.},
  year = 2014,
}

@article{CTT100705319,
  author = {Abe, J. and Nakamura, K. and Nishikomori, R. and Kato, M. and Mitsuiki, N. and Izawa, K. and Awaya, T. and Kawai, T. and Yasumi, T. and Toyoshima, I. and Hasegawa, K. and Ohshima, Y. and Hiragi, T. and Sasahara, Y. and Suzuki, Y. and Kikuchi, M. and Osaka, H. and Ohya, T. and Ninomiya, S. and Fujikawa, S. and Akasaka, M. and Iwata, N. and Kawakita, A. and Funatsuka, M. and Shintaku, H. and Ohara, O. and Hiroshi Ichinose and Heike, T.},
  title = {A nationwide survey of Aicardi-Goutières syndrome patients identifies a strong association between dominant TREX1 mutations and chilblain lesions: Japanese cohort study},
  journal = {Rheumatology (Oxford)},
  year = 2014,
}

@article{CTT100705317,
  author = {Tokuoka, H. and Hatanaka, T. and Metzger, D. and Hiroshi Ichinose},
  title = {Nurr1 expression is regulated by voltage-dependent calcium channels and calcineurin in cultured hippocampal neurons},
  journal = {Neuroscience Letters},
  year = 2014,
}

@article{CTT100705318,
  author = {Horiguchi, M. and Ohi, K. and Hashimoto, R. and Hao, Q. and Yasuda, Y. and Yamamori, H. and Fujimoto, M. and Umeda-Yano, S. and Takeda, M. and Hiroshi Ichinose},
  title = {Functional polymorphism (C-824T) of the tyrosine hydroxylase gene affects IQ in schizophrenia},
  journal = {Psychiatry and Clinical Neurosciences},
  year = 2014,
}

@article{CTT100705320,
  author = {Yasuda, Y. and Hashimoto, R. and Ohi, K. and Yamamori, H. and Fujimoto, M. and Umeda-Yano, S. and Fujino, H. and Fukunaga, M. and Horiguchi, M. and Takeda, M. and Hiroshi Ichinose},
  title = {A functional polymorphism of the GTP cyclohydrolase 1 gene predicts attention performance},
  journal = {Neuroscience Letters},
  year = 2014,
}

@article{CTT100791262,
  author = {一瀬宏},
  title = {ビオプテリンの生理機能と病態代謝},
  journal = {ビタミン},
  year = 2014,
}

@article{CTT100791425,
  author = {村上 てるみ and 西村 敏 and 舟塚 真 and 新宅 治夫 and 一瀬宏 and 大澤 眞木子},
  title = {脳性麻痺と診断されていた瀬川病の女性例},
  journal = {東京女子医科大学雑誌},
  year = 2013,
}

@article{CTT100706713,
  author = {S. Fukuda and M. Horiguchi and K. Yamaguti and Y. Nakatomi and H. Kuratsune and H. Ichinose and Y. Watanabe},
  title = {Association of monoamine-synthesizing genes with the depression tendency and personality in chronic fatigue syndrome patients},
  journal = {Life Sciences},
  year = 2013,
}

@article{CTT100706702,
  author = {I.A. Armata and L. Balaj and J.K. Kuster and X. Zhang and S. Tsai and A.A. Armatas and T.J. Multhaupt-Buell and R. Soberman and X.O. Breakefield and H. Ichinose and N. Sharma},
  title = {Dopa-Responsive Dystonia: Functional Analysis of Single Nucleotide Substitutions within the 5' Untranslated GCH1 Region},
  journal = {PLoS ONE},
  year = 2013,
}

@article{CTT100791607,
  author = {一瀬宏},
  title = {パントテン酸キナーゼ遺伝子の欠損で発症する神経変性疾患NBIA1},
  journal = {ビタミン},
  year = 2013,
}

@article{CTT100706844,
  author = {T. Sekiya and I. Kashiwagi and R. Yoshida and T. Fukaya and R. Morita and A. Kimura and H. Ichinose and D. Metzger and P. Chambon and A. Yoshimura},
  title = {Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis},
  journal = {Nature Immunology},
  year = 2013,
}

@article{CTT100706784,
  author = {N.-C. Lee and Y.-D. Shieh and Y.-H. Chien and K.-Y. Tzen and I.-S. Yu and P.-W. Chen and M.-H. Hu and M.-K. Hu and S.-I. Muramatsu and H. Ichinose and W.-L. Hwu},
  title = {Regulation of the dopaminergic system in a murine model of aromatic l-amino acid decarboxylase deficiency},
  journal = {Neurobiology of Disease},
  year = 2013,
}

@article{CTT100706786,
  author = {Y. Liang and H. Inagaki and Q. Hao and M. Sakamoto and T. Ohye and T. Suzuki and H. Ichinose},
  title = {Identification of an enhancer region for immune activation in the human GTP cyclohydrolase i gene},
  journal = {Biochemical and Biophysical Research Communications},
  year = 2013,
}

@article{CTT100706723,
  author = {W.-L. Hwu and N.-C. Lee and Y.-H. Chien and S.-I. Muramatsu and H. Ichinose},
  title = {AADC deficiency. Occurring in humans, modeled in rodents.},
  journal = {Advances in Pharmacology},
  year = 2013,
}

@article{CTT100706719,
  author = {D. Homma and S. Katoh and H. Tokuoka and H. Ichinose},
  title = {The role of tetrahydrobiopterin and catecholamines in the developmental regulation of tyrosine hydroxylase level in the brain},
  journal = {Journal of Neurochemistry},
  year = 2013,
}

@article{CTT100706720,
  author = {D. Homma and J.P. Kondo and S. Katoh and H. Ichinose},
  title = {Tetrahydrobiopterin Deficiency Impairs Postnatal Increase of TH Protein via Insufficient Dopamine Biosynthesis},
  journal = {Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012},
  year = 2013,
}

@article{CTT100706871,
  author = {T. Toda and D. Homma and H. Tokuoka and I. Hayakawa and Y. Sugimoto and H. Ichinose and H. Kawasaki},
  title = {Birth Regulates the Initiation of Sensory Map Formation through Serotonin Signaling},
  journal = {Developmental Cell},
  year = 2013,
}

@article{CTT100706776,
  author = {T. Kishi and H. Ichinose and R. Yoshimura and Y. Fukuo and T. Kitajima and T. Inada and H. Kunugi and T. Kato and T. Yoshikawa and H. Ujike and G.M. Musso and W. Umene-Nakano and J. Nakamura and N. Ozaki and N. Iwata},
  title = {GTP cyclohydrolase 1 gene haplotypes as predictors of SSRI response in Japanese patients with major depressive disorder},
  journal = {Journal of Affective Disorders},
  year = 2012,
}

@article{CTT100706766,
  author = {T. Kanao and T. Sawada and S.-A. Davies and H. Ichinose and K. Hasegawa and R. Takahashi and N. Hattori and Y. Imai},
  title = {The nitric oxide-cyclic GMP pathway regulates FoxO and alters dopaminergic neuron survival in drosophila},
  journal = {PLoS ONE},
  year = 2012,
}

@article{CTT100706880,
  author = {H. Yagi and S. Sanechika and H. Ichinose and C. Sumi-Ichinose and H. Mizukami and M. Urabe and K. Ozawa and A. Kume},
  title = {Recovery of neurogenic amines in phenylketonuria mice after liver-targeted gene therapy},
  journal = {NeuroReport},
  year = 2012,
}

@article{CTT100632839,
  author = {Tokuoka H and Muramatsu S and Sumi-Ichinose C and Sakane H and Kojima M and Aso Y and Nomura T and Metzger D and Ichinose H.},
  title = {Compensatory Regulation of Dopamine after Ablation of the Tyrosine Hydroxylase Gene in the Nigrostriatal Projection},
  journal = {J Biol Chem.},
  year = 2011,
}

@article{CTT100618927,
  author = {Koshiba S and Tokuoka H and Yokoyama T and Horiuchi E and Ichinose H and Hasegawa K},
  title = {Biopterin levels in the cerebrospinal fluid of patients with PARK8 (I2020T)},
  journal = {J Neural Transm},
  year = 2011,
}

@article{CTT100618926,
  author = {Homma D and Sumi-Ichinose C and Tokuoka H and Ikemoto K and Nomura T and Kondo K and Katoh S and Ichinose H},
  title = {Partial biopterin deficiency disturbs postnatal development of the dopaminergic system in the brain},
  journal = {J Biol Chem},
  year = 2011,
}

@article{CTT100706843,
  author = {T. Sekiya and I. Kashiwagi and N. Inoue and R. Morita and S. Hori and H. Waldmann and A.Y. Rudensky and H. Ichinose and D. Metzger and P. Chambon and A. Yoshimura},
  title = {The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells},
  journal = {Nature Communications},
  year = 2011,
}

@article{CTT100791510,
  author = {一瀬宏 and 小柴 梢子 and 本田 俊一郎 and 徳岡 宏文},
  title = {ビオプテリン測定の現状と課題(ビタミン測定法の現状と課題[V])},
  journal = {ビタミン},
  year = 2011,
}

@article{CTT100706854,
  author = {C. Sumi-Ichinose and H. Ichinose and K. Ikemoto and T. Nomura and K. Kondo},
  title = {Advanced research on dopamine signaling to develop drugs for the treatment of mental disorders: Regulation of dopaminergic neural transmission by tyrosine hydroxylase protein at nerve terminals},
  journal = {Journal of Pharmacological Sciences},
  year = 2010,
}

@article{CTT100706712,
  author = {M. Fukuchi and H. Fujii and H. Takachi and H. Ichinose and Y. Kuwana and A. Tabuchi and M. Tsuda},
  title = {Activation of tyrosine hydroxylase (TH) gene transcription induced by brain-derived neurotrophic factor (BDNF) and its selective inhibition through Ca2+ signals evoked via the N-methyl-d-aspartate (NMDA) receptor},
  journal = {Brain Research},
  year = 2010,
}

@article{CTT100706879,
  author = {H. Yagi and S. Sanechika and H. Ichinose and H. Mizukami and T. Ogura and M. Urabe and H. Hamada and H. Yoshikawa and K. Ozawa and A. Kume},
  title = {LIVER-TARGETED GENE THERAPY WITH A SELF-COMPLEMENTARY AAV AMELIORATED BRAIN AMINERGIC DEFICIT IN PHENYLKETONURIA MICE},
  journal = {Journal of Gene Medicine},
  year = 2010,
}

@article{CTT100590894,
  author = {Kawahata I and Tokuoka H and Parvez H and Ichinose H},
  title = {Accumulation of phosphorylated tyrosine hydroxylase into insoluble protein aggregates by inhibition of an ubiquitin–proteasome system in PC12D cells},
  journal = {Journal of Neural Transmission},
  year = 2009,
}

@article{CTT100590896,
  author = {Ichiro Kawahata and Saburo Yagishita and Kazuko Hasegawa and Ikuko Nagatsu and Toshiharu Nagatsu and Hiroshi Ichinose},
  title = {Immunohistochemical analyses of the postmortem human brains from patients with Parkinson’s disease with anti-tyrosine hydroxylase antibodies},
  journal = {Biogenic Amines},
  year = 2009,
}

@article{CTT100706883,
  author = {S. Yoshikawa and N. Hareyama and K. Ikeda and T. Kurokawa and M. Nakajima and K. Nakao and H. Mochizuki and H. Ichinose},
  title = {Effects of TRK-820, a selective kappa opioid receptor agonist, on rat schizophrenia models},
  journal = {European Journal of Pharmacology},
  year = 2009,
}

@article{CTT100706765,
  author = {B. Kadkhodaei and T. Ito and E. Joodmardi and B. Mattsson and C. Rouillard and M. Carta and S.-I. Muramatsu and C. Sumi-Ichinose and T. Nomura and D. Metzger and P. Chambon and E. Lindqvist and N.-G. Larsson and L. Olson and A. Björklund and H. Ichinose and T. Perlmann},
  title = {Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons},
  journal = {Journal of Neuroscience},
  year = 2009,
}

@article{CTT100706704,
  author = {B. Chavan and W. Beazley and J.M. Wood and H. Rokos and H. Ichinose and K.U. Schallreuter},
  title = {H2O2 increases de novo synthesis of (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin via GTP cyclohydrolase I and its feedback regulatory protein in vitiligo},
  journal = {Journal of Inherited Metabolic Disease},
  year = 2009,
}

@article{CTT100706793,
  author = {K. Momma and M. Funayama and Y. Li and H. Ichinose and K. Motoyoshi and N. Hattori and Y. Mizuno and K. Kamakura},
  title = {A new mutation in the GCH1 gene presents as early-onset Parkinsonism},
  journal = {Parkinsonism and Related Disorders},
  year = 2009,
}

@article{CTT100706779,
  author = {M. Kojima and T. Suzuki and T. Maekawa and S. Ishii and C. Sumi-Ichinose and T. Nomura and H. Ichinose},
  title = {Increased expression of tyrosine hydroxylase and anomalous neurites in catecholaminergic neurons of ATF-2 null mice},
  journal = {Journal of Neuroscience Research},
  year = 2008,
}

@article{CTT100706865,
  author = {C. Takazawa and K. Fujimoto and D. Homma and C. Sumi-Ichinose and T. Nomura and H. Ichinose and S. Katoh},
  title = {A brain-specific decrease of the tyrosine hydroxylase protein in sepiapterin reductase-null mice-as a mouse model for Parkinson's disease},
  journal = {Biochemical and Biophysical Research Communications},
  year = 2008,
}

@article{CTT100706744,
  author = {H. Ichinose and T. Nomura and C. Sumi-Ichinose},
  title = {Metabolism of tetrahydrobiopterin: Its relevance in monoaminergic neurons and neurological disorders},
  journal = {Chemical Record},
  year = 2008,
}

@article{CTT100706841,
  author = {K. Sato and C. Sumi-Ichinose and R. Kaji and K. Ikemoto and T. Nomura and I. Nagatsu and H. Ichinose and M. Ito and W. Sako and S. Nagahiro and A.M. Graybiel and S. Goto},
  title = {Differential involvement of striosome and matrix dopamine systems in a transgenic model of dopa-responsive dystonia},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year = 2008,
}

@article{CTT100706846,
  author = {M. Shimojo and N. Sahara and T. Mizoroki and S. Funamoto and M. Morishima-Kawashima and T. Kudo and M. Takeda and Y. Ihara and H. Ichinose and A. Takashima},
  title = {Enzymatic characteristics of I213T mutant presenilin-1/γ-secretase in cell models and knock-in mouse brains: Familial Alzheimer disease-linked mutation impairs γ-site cleavage of amyloid precursor protein C-terminal fragment β},
  journal = {Journal of Biological Chemistry},
  year = 2008,
}

@article{CTT100706780,
  author = {S. Koshiba and T. Ito and A. Shiota and K. Wakabayashi and M. Ueda and H. Ichinose and T. Ishikawa},
  title = {Development of polyclonal antibodies specific to ATP-binding cassette transporters human ABCG4 and mouse Abcg4: Site-specific expression of mouse Abcg4 in brain},
  journal = {Journal of Experimental Therapeutics and Oncology},
  year = 2007,
}

@article{CTT100706847,
  author = {M. Shimojo and N. Sahara and M. Murayama and H. Ichinose and A. Takashima},
  title = {Decreased Aβ secretion by cells expressing familial Alzheimer's disease-linked mutant presenilin 1},
  journal = {Neuroscience Research},
  year = 2007,
}

@article{CTT100706863,
  author = {T. Suzuki and S. Usuda and H. Ichinose and S. Inouye},
  title = {Real-time bioluminescence imaging of a protein secretory pathway in living mammalian cells using Gaussia luciferase},
  journal = {FEBS Letters},
  year = 2007,
}

@article{CTT100706742,
  author = {H. Ichinose and T. Nagatsu},
  title = {Identification of the causative gene for Segawa's disease},
  journal = {Clinical Neurology},
  year = 2007,
}

@article{CTT100706714,
  author = {H. Furuya and H. Murai and K. Takasugi and Y. Ohyagi and F. Urano and T. Kishi and H. Ichinose and J.-i. Kira},
  title = {A case of late-onset Segawa syndrome (autosomal dominant dopa-responsive dystonia) with a novel mutation of the GTP-cyclohydrase I (GCH1) gene},
  journal = {Clinical Neurology and Neurosurgery},
  year = 2006,
}

@article{CTT100706785,
  author = {X.-G. Li and T. Okada and M. Kodera and Y. Nara and N. Takino and C. Muramatsu and K. Ikeguchi and F. Urano and H. Ichinose and D. Metzger and P. Chambon and I. Nakano and K. Ozawa and S.-I. Muramatsu},
  title = {Viral-mediated temporally controlled dopamine production in a rat model of Parkinson disease},
  journal = {Molecular Therapy},
  year = 2006,
}

@article{CTT100706828,
  author = {S. Ogawa and H. Ichinose},
  title = {Effect of metals and phenylalanine on the activity of human tryptophan hydroxylase-2: Comparison with that on tyrosine hydroxylase activity},
  journal = {Neuroscience Letters},
  year = 2006,
}

@article{CTT100706829,
  author = {S. Ogawa and J. Yamashita and H. Ichinose},
  title = {Characterization of recombinant human tryptophan hydroxylase-2 (hTPH2) fused to maltose-binding protein, and production of anti-hTPH2 antibody},
  journal = {Biogenic Amines},
  year = 2006,
}

@article{CTT100706830,
  author = {E. Ohta and M. Funayama and H. Ichinose and I. Toyoshima and F. Urano and M. Matsuo and N. Tomoko and K. Yukihiko and S. Yoshino and H. Yokoyama and H. Shimazu and K. Maeda and K. Hasegawa and F. Obata},
  title = {Novel mutations in the guanosine triphosphate cyclohydrolase 1 gene associated with DYT5 dystonia},
  journal = {Archives of Neurology},
  year = 2006,
}

@article{CTT100706840,
  author = {K. Sakai and H. Suzuki and H. Oda and T. Akaike and Y. Azuma and T. Murakami and K. Sugi and T. Ito and H. Ichinose and S. Koyasu and M. Shirai},
  title = {Phosphoinositide 3-kinase in nitric oxide synthesis in macrophage: Critical dimerization of inducible nitric-oxide synthase},
  journal = {Journal of Biological Chemistry},
  year = 2006,
}

@article{CTT100708145,
  author = {Fumi Urano and Hayashi N and FUMIO ARISAKA and Hideki Kurita and Murata Shizuaki and Ichinose H},
  title = {Molecular mechanism for pterin-mediated inactivation of tyrosine hydroxylase: Formation of insoluble aggregates of tyrosine hydroxylase},
  journal = {J.Biochem.},
  year = 2006,
}

@article{CTT100706772,
  author = {F. Kawai and M. Horiguchi and H. Ichinose and M. Ohkuma and R. Isobe and E.-I. Miyachi},
  title = {Suppression by an h current of spontaneous Na+ action potentials in human cone and rod photoreceptors},
  journal = {Investigative Ophthalmology and Visual Science},
  year = 2005,
}

@article{CTT100706858,
  author = {C. Sumi-Ichinose and F. Urano and A. Shimomura and T. Sato and K. Ikemoto and H. Shiraishi and T. Senda and H. Ichinose and T. Nomura},
  title = {Genetically rescued tetrahydrobiopterin-depleted mice survive with hyperphenylalaninemia and region-specific monoaminergic abnormalities},
  journal = {Journal of Neurochemistry},
  year = 2005,
}

@article{CTT100706831,
  author = {E. Ohta and I. Toyoshima and M. Funayama and H. Ichinose and K. Hasegawa and F. Obata},
  title = {A new mutation (Thr106Ile) of the GTP cyclohydrolase 1 gene associated with DYT5 dystonia (Segawa Disease) [8]},
  journal = {Movement Disorders},
  year = 2005,
}

@article{CTT100706764,
  author = {T. Ito and T. Suzuki and H. Ichinose},
  title = {Nerve growth factor-induced expression of the GTP cyclohydrolase I gene via Ras/MEK pathway in PC12D cells},
  journal = {Journal of Neurochemistry},
  year = 2005,
}

@article{CTT100706836,
  author = {T. Okuno and Y. Nakatsuji and A. Kumanogoh and M. Moriya and H. Ichinose and H. Sumi and H. Fujimura and H. Kikutani and S. Sakoda},
  title = {Loss of dopaminergic neurons by the induction of inducible nitric oxide synthase and cyclooxygenase-2 via CD40: Relevance to Parkinson's disease},
  journal = {Journal of Neuroscience Research},
  year = 2005,
}

@article{CTT100706860,
  author = {T. Suzuki and H. Kurahashi and H. Ichinose},
  title = {Ras/MEK pathway is required for NGF-induced expression of tyrosine hydroxylase gene},
  journal = {Biochemical and Biophysical Research Communications},
  year = 2004,
}

@article{CTT100706861,
  author = {T. Suzuki and H. Kurita and H. Ichinose},
  title = {GTP cyclohydrolase I utilizes metal-free GTP as its substrate},
  journal = {European Journal of Biochemistry},
  year = 2004,
}

@article{CTT100706774,
  author = {A. Kikuchi and A. Takeda and K. Fujihara and T. Kimpara and Y. Shiga and H. Tanji and M. Nagai and H. Ichinose and F. Urano and N. Okamura and H. Arai and Y. Itoyama},
  title = {Arg(184)His mutant GTP cyclohydrolase I, causing recessive hyperphenylalaninemia, is responsible for dopa-responsive dystonia with Parkinsonism: A case report},
  journal = {Movement Disorders},
  year = 2004,
}

@article{CTT100706848,
  author = {H. Shiraishi and T. Kato and K. Atsuta and C. Sumi-Ichinose and M. Ohtsuki and M. Itoh and H. Hishida and S. Tada and Y. Udagawa and T. Nagatsu and Y. Hagino and H. Ichinose and T. Nomura},
  title = {cGMP inhibits GTP cyclohydrolase I activity and biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells},
  journal = {Journal of Pharmacological Sciences},
  year = 2003,
}

@article{CTT100706749,
  author = {H. Ichinose and T. Ohye and H. Shinotoh and K. Arai and S. Yamazaki and E. Mizuta and S. Kuno and T. Nagatsu},
  title = {Biopterin metabolism in patients with malignant syndrome},
  journal = {Parkinsonism and Related Disorders},
  year = 2003,
}

@article{CTT100706705,
  author = {J. Chen and P. Kuhlencordt and F. Urano and H. Ichinose and J. Astern and P.L. Huang},
  title = {Effects of chronic treatment with L-arginine on atherosclerosis in ApoE knockout and ApoE/inducible NO synthase double-knockout mice},
  journal = {Arteriosclerosis, Thrombosis, and Vascular Biology},
  year = 2003,
}

@article{CTT100706775,
  author = {T.E. Kim and H.S. Lee and Y.B. Lee and S.H. Hong and Y.S. Lee and H. Ichinose and S.U. Kim and M.A. Lee},
  title = {Sonic hedgehog and FGF8 collaborate to induce dopaminergic phenotypes in the Nurr1-overexpressing neural stem cell},
  journal = {Biochemical and Biophysical Research Communications},
  year = 2003,
}

@article{CTT100706881,
  author = {T. Yamakuni and T. Suzuki and H. Inagaki and Y. Ohizumi and T. Nagatsu and H. Ichinose},
  title = {V-1, a catecholamine biosynthesis regulatory protein, enhances GTP cyclohydrolase I gene transcription in a camp-responsive element dependent manner},
  journal = {Folia Pharmacologica Japonica},
  year = 2002,
}

@article{CTT100706864,
  author = {T. Suzuki and T. Yamakuni and M. Hagiwara and H. Ichinose},
  title = {Identification of ATF-2 as a transcriptional regulator for the tyrosine hydroxylase gene},
  journal = {Journal of Biological Chemistry},
  year = 2002,
}

@article{CTT100706823,
  author = {A.L. Nielsen and C. Sanchez and H. Ichinose and M. Cerviño and T. Lerouge and P. Chambon and R. Losson},
  title = {Selective interaction between the chromatin-remodeling factor BRG1 and the heterochromatin-associated protein HP1α},
  journal = {EMBO Journal},
  year = 2002,
}

@article{CTT100706758,
  author = {M. Ihara and N. Kohara and F. Urano and H. Ichinose and S. Takao and T. Nishida and H. Saiki and Y. Kawamoto and A. Ikeda and S. Takagi and H. Shibasaki},
  title = {Neuroleptic malignant syndrome with prolonged catatonia in a dopa-responsive dystonia patient},
  journal = {Neurology},
  year = 2002,
}

@article{CTT100706759,
  author = {K. Ikemoto and T. Sugimoto and S. Murata and M. Tazawa and T. Nomura and H. Ichinose and T. Nagatsu},
  title = {(6R)-5,6,7,8-tetrahydro-L-monapterin from Escherichia coli, a novel natural unconjugated tetrahydropterin},
  journal = {Biological Chemistry},
  year = 2002,
}

@article{CTT100706760,
  author = {K. Ikemoto and T. Suzuki and H. Ichinose and T. Ohye and A. Nishimura and K. Nishi and I. Nagatsu and T. Nagatsu},
  title = {Localization of sepiapterin reductase in the human brain},
  journal = {Brain Research},
  year = 2002,
}

@article{CTT100706761,
  author = {M. Ikeno and H. Inagaki and K. Nagata and M. Morita and H. Ichinose and T. Okazaki},
  title = {Generation of human artificial chromosomes expressing naturally controlled guanosine triphosphate cyclohydrolase I gene},
  journal = {Genes to Cells},
  year = 2002,
}

@article{CTT100706706,
  author = {N. Chen and K. Ikemoto and T. Sugimoto and S. Murata and H. Ichinose and T. Nagatsu},
  title = {A highly sensitive and specific fdcd method for chirality analysis of naturally occurring pteridines},
  journal = {Heterocycles},
  year = 2002,
}

@article{CTT100706832,
  author = {M. Ohtsuki and H. Shiraishi and T. Kato and R. Kuroda and M. Tazawa and C. Sumi-Ichinose and S. Tada and Y. Udagawa and M. Itoh and H. Hishida and H. Ichinose and T. Nagatsu and Y. Hagino and T. Nomura},
  title = {cAMP inhibits cytokine-induced biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells},
  journal = {Life Sciences},
  year = 2002,
}

@article{CTT100706773,
  author = {H. Kawasaki and H. Suemori and K. Mizuseki and K. Watanabe and F. Urano and H. Ichinose and M. Haruta and M. Takahashi and K. Yoshikawa and S.-I. Nishikawa and N. Nakatsuji and Y. Sasai},
  title = {Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity},
  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year = 2002,
}

@article{CTT100706783,
  author = {M.A. Lee and H.-S. Lee and H.S. Lee and K.G. Cho and B.K. Jin and S. Sohn and Y.S. Lee and H. Ichinose and S.U. Kim},
  title = {Overexpression of midbrain-specific transcription factor Nurr1 modifies susceptibility of mouse neural stem cells to neurotoxins},
  journal = {Neuroscience Letters},
  year = 2002,
}

@article{CTT100706794,
  author = {S.-I. Muramatsu and A. Kume and M. Matsumura and I. Nagatsu and F. Urano and H. Ichinose and T. Nagatsu and K. Terao and I. Nakano and K. Ozawa and K.-I. Fujimoto and K. Ikeguchi and N. Shizuma and K. Kawasaki and F. Ono and Y. Shen and L. Wang and H. Mizukami},
  title = {Behavioral recovery in a primate model of Parkinson's disease by triple transduction of striatal cells with adeno-associated viral vectors expressing dopamine-synthesizing enzymes},
  journal = {Human Gene Therapy},
  year = 2002,
}

@article{CTT100706877,
  author = {L. Wang and S. Muramatsu and Y. Lu and K. Ikeguchi and K. Fujimoto and T. Okada and H. Mizukami and Y. Hanazono and A. Kume and F. Urano and H. Ichinose and T. Nagatsu and I. Nakano and K. Ozawa},
  title = {Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease},
  journal = {Gene Therapy},
  year = 2002,
}

@article{CTT100706859,
  author = {T. Suzuki and H. Inagaki and T. Yamakuni and T. Nagatsu and H. Ichinose},
  title = {Enhanced expression of GTP cyclohydrolase I in V-1-overexpressing PC12D cells},
  journal = {Biochemical and Biophysical Research Communications},
  year = 2002,
}

@article{CTT100706756,
  author = {H. Ichinose and T. Suzuki and H. Inagaki and T. Ohye and T. Nagatsu},
  title = {DOPA-responsive dystonia. From causative gene to molecular mechanism.},
  journal = {Advances in neurology},
  year = 2001,
}

@article{CTT100706788,
  author = {M. Mogi and A. Togari and T. Kondo and Y. Mizuno and O. Kogure and S. Kuno and H. Ichinose and T. Nagatsu},
  title = {Glial cell line-derived neurotrophic factor in the substantia nigra from control and parkinsonian brains},
  journal = {Neuroscience Letters},
  year = 2001,
}

@article{CTT100706849,
  author = {T. Sugimoto and K. Ikemoto and S. Murata and M. Tazawa and T. Nomura and Y. Hagino and H. Ichinose and T. Nagatsu},
  title = {Identification of (6R)-5,6,7,8-tetrahydro-D-monapterin (=(6R)-2-amino-5,6,7,8-tetrahydro-6-[(1R,2R)-1,2,3 -trihydroxypropyl]-pteridin-4(3H)-one) as the native pteridine in Tetrahymena pyriformis},
  journal = {Helvetica Chimica Acta},
  year = 2001,
}

@article{CTT100706850,
  author = {T. Sugimoto and K. Ikemoto and S. Murata and M. Tazawa and T. Nomura and Y. Hagino and H. Ichinose and T. Nagatsu and A. Wada},
  title = {A convenient determination of chiral pteridines; application of fluorescence detected circular dichroism (FDCD) to the major pterin from Escherichia coli},
  journal = {Heterocycles},
  year = 2001,
}

@article{CTT100706884,
  author = {C.P. Zabetian and G.M. Anderson and S.G. Buxbaum and R.C. Elston and H. Ichinose and T. Nagatsu and K.-S. Kim and C.-H. Kim and R.T. Malison and J. Gelernter and J.F. Cubells},
  title = {A quantitative-trait analysis of human plasma-dopamine β-hydroxylase activity: Evidence for a major functional polymorphism at the DBH locus},
  journal = {American Journal of Human Genetics},
  year = 2001,
}

@article{CTT100706835,
  author = {T. Ohye and H. Ichinose and T. Yoshizawa and I. Kanazawa and T. Nagatsu},
  title = {A new splicing variant for human tyrosine hydroxylase in the adrenal medulla},
  journal = {Neuroscience Letters},
  year = 2001,
}

@article{CTT100706857,
  author = {C. Sumi-Ichinose and F. Urano and R. Kuroda and T. Ohye and M. Kojima and M. Tazawa and H. Shiraishi and Y. Hagino and T. Nagatsu and T. Nomura and H. Ichinose},
  title = {Catecholamines and serotonin are differently regulated by tetrahydrobiopterin. A study from 6-pyruvoyltetrahydropterin synthase knockout mice},
  journal = {Journal of Biological Chemistry},
  year = 2001,
}

@article{CTT100706731,
  author = {H. Ichinose and H. Inagaki and T. Suzuki and T. Ohye and T. Nagatsu},
  title = {Molecular mechanisms of hereditary progressive dystonia with marked diurnal fluctuation, Segawa's disease},
  journal = {Brain and Development},
  year = 2000,
}

@article{CTT100706707,
  author = {J.F. Cubells and C.P. Zabetian and G.M. Anderson and H.R. Kranzler and H. Ichinose and T. Nagatsu},
  title = {Dopamine beta-hydroxylase: Genotype-phenotype relationships},
  journal = {American Journal of Medical Genetics - Neuropsychiatric Genetics},
  year = 2000,
}

@article{CTT100706769,
  author = {S. Kaneko and T. Hikida and D. Watanabe and H. Ichinose and T. Nagatsu and R.J. Kreitman and I. Pastan and S. Nakanishi},
  title = {Synaptic integration mediated by striatal cholinergic interneurons in basal ganglia function},
  journal = {Science},
  year = 2000,
}

@article{CTT100706792,
  author = {M. Mogi and A. Togari and K.-I. Tanaka and N. Ogawa and H. Ichinose and T. Nagatsu},
  title = {Increase in level of tumor necrosis factor-α in 6-hydroxydopamine- lesioned striatum in rats is suppressed by immunosuppressant FK506},
  journal = {Neuroscience Letters},
  year = 2000,
}

@article{CTT100706866,
  author = {M. Tazawa and M. Ohtsuki and C. Sumi-Ichinose and H. Shiraishi and R. Kuroda and Y. Hagino and S. Nakashima and Y. Nozawa and H. Ichinose and T. Nagatsu and T. Nomura},
  title = {GTP cyclohydrolase I from Tetrahymena pyriformis: Cloning of cDNA and expression},
  journal = {Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology},
  year = 2000,
}

@article{CTT100706718,
  author = {M. Hibiya and H. Ichinose and N. Ozaki and K. Fujita and T. Nishimoto and T. Yoshikawa and Y. Asano and T. Nagatsu},
  title = {Normal values and age-dependent changes in GTP cyclohydrolase I activity in stimulated mononuclear blood cells measured by high-performance liquid chromatography},
  journal = {Journal of Chromatography B: Biomedical Sciences and Applications},
  year = 2000,
}

@article{CTT100706787,
  author = {T. Maeda and S. Haeno and K. Oda and D. Mori and H. Ichinose and T. Nagatsu and T. Suzuki},
  title = {Studies on the genotype-phenotype relation in the hph-1 mouse mutant deficient in guanosine triphosphate (GTP) cyclohydrolase I activity},
  journal = {Brain and Development},
  year = 2000,
}

@article{CTT100706812,
  author = {T. Nagatsu and M. Mogi and H. Ichinose and A. Togari},
  title = {Cytokines in Parkinson's disease},
  journal = {Journal of Neural Transmission, Supplement},
  year = 2000,
}

@article{CTT100706811,
  author = {T. Nagatsu and M. Mogi and H. Ichinose and A. Togari},
  title = {Changes in cytokines and neurotrophins in Parkinson's disease},
  journal = {Journal of Neural Transmission, Supplement},
  year = 2000,
}

@article{CTT100706845,
  author = {Y. Shen and I. Nagatsu and F. Urano and T. Suzuki and H. Ichinose and T. Nagatsu and J. Monahan and I. Nakano and K. Ozawa and S.-I. Muramatsu and K. Ikeguchi and K.-I. Fujimoto and D.-S. Fan and M. Ogawa and H. Mizukami and M. Urabe and A. Kume},
  title = {Triple transduction with adeno-associated virus vectors expressing tyrosine hydroxylase, aromatic-L-amino-acid decarboxylase, and GTP cyclohydrolase I for gene therapy of Parkinson's disease},
  journal = {Human Gene Therapy},
  year = 2000,
}

@article{CTT100706726,
  author = {H. Ichinose},
  title = {Segawa's disease},
  journal = {Clinical Neurology},
  year = 2000,
}

@article{CTT100706790,
  author = {M. Mogi and A. Togari and T. Kondo and Y. Mizuno and O. Komure and S. Kuno and H. Ichinose and T. Nagatsu},
  title = {Caspase activities and tumor necrosis factor receptor R1 (p55) level are elevated in the substantia nigra from Parkinsonian brain},
  journal = {Journal of Neural Transmission},
  year = 2000,
}

@article{CTT100706813,
  author = {T. Nagatsu and M. Mogi and H. Ichinose and A. Togari and P. Riederer},
  title = {Cytokines in Parkinson's disease},
  journal = {NeuroScience News},
  year = 1999,
}

@article{CTT100706805,
  author = {T. Nagatsu and H. Ichinose},
  title = {Regulation of pteridine-requiring enzymes by the cofactor tetrahydrobiopterin},
  journal = {Molecular Neurobiology},
  year = 1999,
}

@article{CTT100706804,
  author = {T. Nagatsu and H. Ichinose},
  title = {Molecular biology of catecholamine-related enzymes in relation to Parkinson's disease},
  journal = {Cellular and Molecular Neurobiology},
  year = 1999,
}

@article{CTT100706862,
  author = {T. Suzuki and T. Ohye and H. Inagaki and T. Nagatsu and H. Ichinose},
  title = {Characterization of wild-type and mutants of recombinant human GTP cyclohydrolase I: Relationship to etiology of dopa-responsive dystonia},
  journal = {Journal of Neurochemistry},
  year = 1999,
}

@article{CTT100706797,
  author = {I. Nagatsu and K. Ikemoto and K. Kitahama and A. Nishimura and H. Ichinose and T. Nagatsu},
  title = {Specific localization of the guanosine triphosphate (GTP) cyclohydrolase I-immunoreactivity in the human brain},
  journal = {Journal of Neural Transmission},
  year = 1999,
}

@article{CTT100706791,
  author = {M. Mogi and A. Togari and K.-I. Tanaka and N. Ogawa and H. Ichinose and T. Nagatsu},
  title = {Increase in level of tumor necrosis factor (TNF)-α in 6- hydroxydopamine-lesioned striatum in rats without influence of systemic L- DOPA on the TNF-α induction},
  journal = {Neuroscience Letters},
  year = 1999,
}

@article{CTT100706789,
  author = {M. Mogi and A. Togari and T. Kondo and Y. Mizuno and O. Komure and S. Kuno and H. Ichinose and T. Nagatsu},
  title = {Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease},
  journal = {Neuroscience Letters},
  year = 1999,
}

@article{CTT100706763,
  author = {C. Itagaki and T. Isobe and M. Taoka and T. Natsume and N. Nomura and T. Horigome and S. Omata and H. Ichinose and T. Nagatsu and L.A. Greene and T. Ichimura},
  title = {Stimulus-coupled interaction of tyrosine hydroxylase with 14-3-3 proteins},
  journal = {Biochemistry},
  year = 1999,
}

@article{CTT100706762,
  author = {H. Inagaki and T. Ohye and T. Suzuki and M. Segawa and Y. Nomura and T. Nagatsu and H. Ichinose},
  title = {Decrease in GTP cyclohydrolase I gene expression caused by inactivation of one allele in hereditary progressive dystonia with marked diurnal fluctuation},
  journal = {Biochemical and Biophysical Research Communications},
  year = 1999,
}

@article{CTT100706755,
  author = {H. Ichinose and T. Suzuki and H. Inagaki and T. Ohye and T. Nagatsu},
  title = {Molecular genetics of dopa-responsive dystonia},
  journal = {Biological Chemistry},
  year = 1999,
}

@article{CTT100706751,
  author = {H. Ichinose and T. Ohye and T. Suzuki and C. Sumi-Ichinose and T. Nomura and Y. Hagino and T. Nagatsu},
  title = {Molecular cloning of the human Nurr1 gene: Characterization of the human gene and cDNAs},
  journal = {Gene},
  year = 1999,
}

@article{CTT100706750,
  author = {H. Ichinose and T. Ohye and T. Suzuki and H. Inagaki and T. Nagatsu},
  title = {The relation between metabolism of biopterin and dystonia-parkinsonism},
  journal = {Japanese Journal of Psychopharmacology},
  year = 1999,
}

@article{CTT100706741,
  author = {H. Ichinose and T. Nagatsu},
  title = {Molecular genetics of DOPA-responsive dystonia.},
  journal = {Advances in neurology},
  year = 1999,
}

@article{CTT100706710,
  author = {K. Fujimoto and H. Ichinose and T. Nagatsu and T. Nonaka and Y. Mitsui and S. Katoh},
  title = {Functionally important residues tyrosine-171 and serine-158 in sepiapterin reductase},
  journal = {Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology},
  year = 1999,
}

@article{CTT100706808,
  author = {T. Nagatsu and H. Ichinose and M. Mogi and A. Togari},
  title = {Neopterin and cytokines in hereditary dystonia and Parkinson's disease},
  journal = {Pteridines},
  year = 1999,
}

@article{CTT100706708,
  author = {D.-S. Fan and M. Ogawa and K.-I. Fujimoto and K. Ikeguchi and Y. Ogasawara and M. Urabe and M. Nishizawa and I. Nakano and M. Yoshida and I. Nagatsu and H. Ichinose and T. Nagatsu and G.J. Kurtzman and K. Ozawa},
  title = {Behavioral recovery in 6-hydroxydopamine-lesioned rats by cotransduction of striatum with tyrosine hydroxylase and aromatic L-amino acid decarboxylase genes using two separate adeno-associated virus vectors},
  journal = {Human Gene Therapy},
  year = 1998,
}

@article{CTT100706715,
  author = {J. Gelernter and H. Kranzler and J.F. Cubells and H. Ichinose and T. Nagatsu},
  title = {DRD2 allele frequencies and linkage disequilibria, including the - 141CIns/Del promoter polymorphism, in European-American, African-American, and Japanese subjects},
  journal = {Genomics},
  year = 1998,
}

@article{CTT100706833,
  author = {T. Ohye and T.-A. Hori and S. Katoh and T. Nagatsu and H. Ichinose},
  title = {Genomic organization and chromosomal localization of the human sepiapterin reductase gene},
  journal = {Biochemical and Biophysical Research Communications},
  year = 1998,
}

@article{CTT100706802,
  author = {T. Nagatsu and H. Ichinose},
  title = {Genetic basis of dominant dystonia.},
  journal = {Advances in pharmacology (San Diego, Calif.)},
  year = 1998,
}

@article{CTT100706709,
  author = {D.-S. Fan and M. Ogawa and K. Ikeguchi and K.-I. Fujimoto and M. Urabe and A. Kume and M. Nishizawa and N. Matsushita and K. Kiuchi and H. Ichinose and T. Nagatsu and G.J. Kurtzman and I. Nakano and K. Ozawa},
  title = {Prevention of dopaminergic neuron death by adeno-associated virus vector-mediated GDNF gene transfer in rat mesencephalic cells in vitro},
  journal = {Neuroscience Letters},
  year = 1998,
}

@article{CTT100706827,
  author = {T. Nomura and M. Tazawa and M. Ohtsuki and C. Sumi-Ichinose and Y. Hagino and A. Ota and A. Nakashima and K. Mori and T. Sugimoto and O. Ueno and Y. Nozawa and H. Ichinose and T. Nagatsu},
  title = {Enzymes related to catecholamine biosynthesis in Tetrahymena pyriformis. Presence of GTP cyclohydrolase I},
  journal = {Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology},
  year = 1998,
}

@article{CTT100706803,
  author = {T. Nagatsu and H. Ichinose},
  title = {Molecular biology of hereditary dystonia},
  journal = {No To Hattatsu},
  year = 1998,
}

@article{CTT100706801,
  author = {T. Nagatsu and H. Ichinose},
  title = {Autosomal dominant DOPA-responsive dystonia caused by mutations in GTP cyclohydrolase I gene},
  journal = {Voprosy Meditsinskoj Khimii},
  year = 1998,
}

@article{CTT100706729,
  author = {H. Ichinose and J.-M. Gamier and P. Chambon and R. Losson},
  title = {Ligand-dependent interaction between the estrogen receptor and the human homologues of SWI2/SNF2},
  journal = {Gene},
  year = 1997,
}

@article{CTT100706739,
  author = {H. Ichinose and T. Nagatsu},
  title = {Molecular genetics of DOPA-responsive dystonia (Segawa's disease) - Recent advances},
  journal = {Japanese Journal of Neuropsychopharmacology},
  year = 1997,
}

@article{CTT100706855,
  author = {C. Sumi-Ichinose and H. Ichinose and D. Metzger and P. Chambon},
  title = {SNF2β-BRG1 is essential for the viability of F9 murine embryonal carcinoma cells},
  journal = {Molecular and Cellular Biology},
  year = 1997,
}

@article{CTT100706740,
  author = {H. Ichinose and T. Nagatsu},
  title = {Molecular genetics of hereditary dystonia - Mutations in the GTP cyclohydrolase I gene},
  journal = {Brain Research Bulletin},
  year = 1997,
}

@article{CTT100706799,
  author = {T. Nagatsu and H. Ichinose},
  title = {Molecular biology of catecholamine neurons in relation to Parkinson's disease.},
  journal = {Advances in neurology},
  year = 1996,
}

@article{CTT100706798,
  author = {T. Nagatsu and H. Ichinose},
  title = {GTP cyclohydrolase I gene, tetrahydrobiopterin, and tyrosine hydroxylase gene: Their relations to dystonia and parkinsonism},
  journal = {Neurochemical Research},
  year = 1996,
}

@article{CTT100706809,
  author = {T. Nagatsu and H. Ichinose and T. Ohye},
  title = {Molecular aspects of the dopaminergic neurotoxins in relation to tyrosine hydroxylase isoforms},
  journal = {Biogenic Amines},
  year = 1996,
}

@article{CTT100706716,
  author = {S. Haeno and T. Maeda and M. Abe and K. Oda and T. Suzuki and H. Ichinose and T. Nagatsu},
  title = {Molecular genetic and metabolic aspects of hph-1,a mouse mutant deficient in gtp cyclohydrolase i activity},
  journal = {Japanese Journal of Human Genetics},
  year = 1996,
}

@article{CTT100706782,
  author = {B. LeDouarin and A. L. Nielsen and J. M. Garnier and H. Ichinose and F. Jeanmougin and R. Losson and P. Chambon},
  title = {A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors},
  journal = {Embo Journal},
  year = 1996,
}

@article{CTT100706738,
  author = {H. Ichinose and T. Nagatsu},
  title = {Molecular genetics of hereditary progressive dystonia (HPD/Segawa's disease)},
  journal = {Nippon rinsho. Japanese journal of clinical medicine},
  year = 1996,
}

@article{CTT100706796,
  author = {I. Nagatsu and H. Ichinose and M. Sakai and K. Titani and M. Suzuki and T. Nagatsu},
  title = {Immunocytochemical localization of GTP cyclohydrolase I in the brain, adrenal gland, and liver of mice},
  journal = {Journal of Neural Transmission},
  year = 1995,
}

@article{CTT100706853,
  author = {C. Sumi-Ichinose and S. Hasegawa and H. Ichinose and H. Sawada and K. Kobayashi and M. Sakai and T. Fujii and H. Nomura and T. Nomura and I. Nagatsu and Y. Hagino and K. Fujita and T. Nagatsu},
  title = {Analysis of the alternative promoters that regulate tissue-specific expression of human aromatic L-amino acid decarboxylase},
  journal = {Journal of Neurochemistry},
  year = 1995,
}

@article{CTT100706728,
  author = {H. Ichinose and N. Blau and R. Matalon and T. Nagatsu},
  title = {Genomic organization of mouse and human GTP cyclohydrolase I genes and mutations found in the human gene},
  journal = {Pteridines},
  year = 1995,
}

@article{CTT100706737,
  author = {H. Ichinose and T. Nagatsu},
  title = {GTP cyclohydrolase I gene and hereditary dystonia},
  journal = {Japanese Journal of Neuropsychopharmacology},
  year = 1995,
}

@article{CTT100706703,
  author = {N. Blau and H. Ichinose and T. Nagatsu and C.W. Heizmann and F. Zacchello and A.B. Burlina},
  title = {A missense mutation in a patient with guanosine triphosphate cyclohydrolase I deficiency missed in the newborn screening program},
  journal = {The Journal of Pediatrics},
  year = 1995,
}

@article{CTT100706838,
  author = {A. Ota and H. Ichinose and T. Nagatsu},
  title = {Mouse sepiapterin reductase: an enzyme involved in the final step of tetrahydrobiopterin biosynthesis. Primary structure deduced from the cDNA sequence},
  journal = {BBA - Gene Structure and Expression},
  year = 1995,
}

@article{CTT100706834,
  author = {T. Ohye and H. Ichinose and M. Ogawa and M. Yoshida and T. Nagatsu},
  title = {Alterations in multiple tyrosine hydroxylase mRNAs in the substantia nigra, locus coeruleus and adrenal gland of MPTP-treated parkinsonian monkeys},
  journal = {Neurodegeneration},
  year = 1995,
}

@article{CTT100706747,
  author = {H. Ichinose and T. Ohye and Y. Matsuda and T.-A. Hori and N. Blau and A. Burlina and B. Rouse and R. Matalon and K. Fujita and T. Nagatsu},
  title = {Characterization of mouse and human GTP cyclohydrolase I genes: Mutations in patients with GTP cyclohydrolase I deficiency},
  journal = {Journal of Biological Chemistry},
  year = 1995,
}

@article{CTT100706826,
  author = {T. Nomura and M. Ohtsuki and S. Matsui and C. Sumi-Ichinose and H. Nomura and Y. Hagino and K. Iwase and H. Ichinose and K. Fujita and T. Nagatsu},
  title = {Isolation of a full-length cDNA clone for human GTP cyclohydrolase I type 1 from pheochromocytoma},
  journal = {Journal of Neural Transmission - General Section},
  year = 1995,
}

@article{CTT100706748,
  author = {H. Ichinose and T. Ohye and M. Segawa and Y. Nomura and K. Endo and H. Tanaka and S. Tsuji and K. Fujita and T. Nagatsu},
  title = {GTP cyclohydrolase I gene in hereditary progressive dystonia with marked diurnal fluctuation},
  journal = {Neuroscience Letters},
  year = 1995,
}

@article{CTT100706753,
  author = {H. Ichinose and T. Ohye and M. Yokochi and K. Fujit and T. Nagatsu},
  title = {GTP cyclohydrolase I activity in mononuclear blood cells in juvenile parkinsonism},
  journal = {Neuroscience Letters},
  year = 1995,
}

@article{CTT100706752,
  author = {H. Ichinose and T. Ohye and E.-I. Takahashi and N. Seki and T.-A. Hori and M. Segawa and Y. Nomura and K. Endo and H. Tanaka and S. Tsuji and K. Fujita and T. Nagatsu},
  title = {Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene},
  journal = {Nature Genetics},
  year = 1994,
}

@article{CTT100706837,
  author = {A. Ota and H. Ichinose and K. Kobayashi and S. Morita and H. Sawada and T. Mizuguchi and T. Nagatsu},
  title = {Nicotine-induced regulation of tyrosine hydroxylase activity in adrenal gland of transgenic mouse carrying human tyrosine hydroxylase gene},
  journal = {Neuroscience Letters},
  year = 1994,
}

@article{CTT100706821,
  author = {S. Nasrin and H. Ichinose and H. Hidaka and T. Nagatsu},
  title = {Recombinant human tyrosine hydroxylase types 1-4 show regulatory kinetic properties for the natural (6R)-tetrahydrobiopterin cofactor},
  journal = {Journal of Biochemistry},
  year = 1994,
}

@article{CTT100706745,
  author = {H. Ichinose and T. Ohye and K. Fujita and F. Pantucek and K. Lange and P. Riederer and T. Nagatsu},
  title = {Quantification of mRNA of tyrosine hydroxylase and aromatic L-amino acid decarboxylase in the substantia nigra in Parkinson's disease and schizophrenia},
  journal = {Journal of Neural Transmission - Parkinson's Disease and Dementia Section},
  year = 1994,
}

@article{CTT100706868,
  author = {T. Terasaki and Y. Matsuno and Y. Shimosato and K. Yamaguchi and H. Ichinose and T. Nagatsu and K. Kato},
  title = {Establishment of a human small cell lung cancer cell line producing a large amount of anti-diuretic hormone},
  journal = {Japanese Journal of Cancer Research},
  year = 1994,
}

@article{CTT100706711,
  author = {T. Fujiwara and T. Motoyama and N. Ishihara and H. Watanabe and T. Kumanishi and K. Kato and H. Ichinose and T. Nagatsu},
  title = {Characterization of four new cell lines derived from small-cell gastrointestinal carcinoma},
  journal = {International Journal of Cancer},
  year = 1993,
}

@article{CTT100706736,
  author = {H. Ichinose and T. Nagatsu},
  title = {Molecular genetics of aromatic L-amino acid decarboxylase},
  journal = {Japanese Journal of Psychopharmacology},
  year = 1993,
}

@article{CTT100706825,
  author = {T. Nomura and H. Ichinose and C. Sumi-Ichinose and H. Nomura and Y. Hagino and K. Fujita and T. Nagatsu},
  title = {Cloning and sequencing of cDNA encoding mouse GTP cyclohydrolase I},
  journal = {Biochemical and Biophysical Research Communications},
  year = 1993,
}

@article{CTT100706746,
  author = {H. Ichinose and T. Ohye and K. Fujita and M. Yoshida and S. Ueda and T. Nagatsu},
  title = {Increased heterogeneity of tyrosine hydroxylase in humans},
  journal = {Biochemical and Biophysical Research Communications},
  year = 1993,
}

@article{CTT100706806,
  author = {T. Nagatsu and H. Ichinose and S. Katoh and K. Fujita and K. Titani},
  title = {6R-tetrahydrobiopterin biosynthesis: structures of rat and human sepiapterin reductase.},
  journal = {Journal of Nutritional Science and Vitaminology},
  year = 1992,
}

@article{CTT100706873,
  author = {A. Togari and H. Ichinose and S. Matsumoto and K. Fujita and T. Nagatsu},
  title = {Multiple mRNA forms of human GTP cyclohydrolase I},
  journal = {Biochemical and Biophysical Research Communications},
  year = 1992,
}

@article{CTT100706856,
  author = {C. Sumi-Ichinose and H. Ichinose and E.-I. Takahashi and T.-A. Hori and T. Nagatsu},
  title = {Molecular cloning of genomic DNA and chromosomal assignment of the gene for human aromatic L-amino acid decarboxylase, the enzyme for catecholamine and serotonin biosynthesis},
  journal = {Biochemistry},
  year = 1992,
}

@article{CTT100706754,
  author = {H. Ichinose and C. Sumi-Ichinose and T. Ohye and Y. Hagino and K. Fujita and T. Nagatsu},
  title = {Tissue-specific alternative splicing of the first exon generates two types of mRNAs in human aromatic L-amino acid decarboxylase},
  journal = {Biochemistry},
  year = 1992,
}

@article{CTT100706733,
  author = {H. Ichinose and S. Katoh and T. Sueoka and K. Titani and K. Fujita and T. Nagatsu},
  title = {Cloning and sequencing of cDNA encoding human sepiapterin reductase},
  journal = {Pteridines},
  year = 1992,
}

@article{CTT100706822,
  author = {S. Nasrin and H. Ichinose and T. Nagatsu},
  title = {Comparison of characteristics of bovine aromatic l-amino acid decarboxylase with human enzyme},
  journal = {Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular},
  year = 1992,
}

@article{CTT100706732,
  author = {H. Ichinose and S. Katoh and T. Sueoka and K. Titani and K. Fujita and T. Nagatsu},
  title = {Cloning and sequencing of cDNA encoding human sepiapterin reductase. An enzyme involved in tetrahydrobiopterin biosynthesis},
  journal = {Biochemical and Biophysical Research Communications},
  year = 1991,
}

@article{CTT100706852,
  author = {C. Sumi and H. Ichinose and T. Nagatsu},
  title = {Characterization of recombinant human aromatic l-amino acid decarboxylase expressed in COS cells},
  journal = {Journal of Neurochemistry},
  year = 1990,
}

@article{CTT100706839,
  author = {R. Oyama and S. Katoh and T. Sueoka and M. Suzuki and H. Ichinose and T. Nagatsu and K. Titani},
  title = {The complete amino acid sequence of the mature form of rat sepiapterin reductase},
  journal = {Biochemical and Biophysical Research Communications},
  year = 1990,
}

@article{CTT100706725,
  author = {S. Ichikawa and H. Ichinose and T. Nagatsu},
  title = {Multiple mRNAs of monkey tyrosine hydroxylase},
  journal = {Biochemical and Biophysical Research Communications},
  year = 1990,
}

@article{CTT100706735,
  author = {H. Ichinose and Y. Kurosawa and K. Titani and K. Fujita and T. Nagatsu},
  title = {Isolation and characterization of a cDNA clone encoding human aromatic L-amino acid decarboxylase},
  journal = {Biochemical and Biophysical Research Communications},
  year = 1989,
}

@article{CTT100706820,
  author = {M. Naoi and T. Takahashi and H. Ichinose and K. Wakabayashi and T. Sugimura and T. Nagatsu},
  title = {Uptake of heterocyclic amines, Trp-P-1 and Trp-P-2, into clonal rat pheochromocytoma PC12h cells by dopamine uptake system},
  journal = {Neuroscience Letters},
  year = 1989,
}

@article{CTT100706795,
  author = {I. Nagatsu and S. Furune and H. Ichinose and M. Spatz and T. Nagatsu},
  title = {Quantitative analysis of reduction of aromatic-L-aminoacid decarboxylase- and tyrosine hydroxylase-like immunoreactivities in the nigrostriatal dopaminergic neurons of MPTP-treated mice},
  journal = {Biogenic Amines},
  year = 1989,
}

@article{CTT100706819,
  author = {M. Naoi and T. Takahashi and H. Ichinose and K. Wakabayashi and T. Sugimura and T. Nagatsu},
  title = {Reduction of enzyme activity of tyrosine hydroxylase and aromatic L-aminoacid decarboxylase in clonal pheochromocytoma PC12h cells by carcinogenic heterocyclic amines},
  journal = {Biochemical and Biophysical Research Communications},
  year = 1988,
}

@article{CTT100706816,
  author = {M. Naoi and H. Ichinose and T. Takahashi and I. Nagatsu and T. Nagatsu},
  title = {Reduction of aromatic l-amino acid decarboxylase activity in clonal pheochromocytoma PC12h cells by culture in the presence of N-methyl-4-phenylpyridinium ion (MPP+)},
  journal = {Neuroscience Letters},
  year = 1988,
}

@article{CTT100706778,
  author = {K. Kobayashi and N. Kaneda and H. Ichinose and F. Kishi and A. Nakazawa and Y. Kurosawa and K. Fujita and T. Nagatsu},
  title = {Structure of the human tyrosine hydroxylase gene: Alternative splicing from a single gene accounts for generation of four mRNA types},
  journal = {Journal of Biochemistry},
  year = 1988,
}

@article{CTT100706818,
  author = {M. Naoi and T. Takahashi and H. Ichinose and T. Nagatsu},
  title = {Inhibition of aromatic L-aminoacid decarboxylase in clonal pheochromocytoma PC12h cells by N-methyl-4-phenylpyridinium ion (MPP+)},
  journal = {Biochemical and Biophysical Research Communications},
  year = 1988,
}

@article{CTT100706872,
  author = {A. Togari and H. Ichinose and K. Kojima and Y. Hirata and T. Nagatsu},
  title = {Centrally mediated activation of tyrosine hydroxylation in rat adrenals by thyrotropin-releasing hormone},
  journal = {Biochemical Pharmacology},
  year = 1988,
}

@article{CTT100706824,
  author = {I. Nishigaki and H. Ichinose and K. Tamai and T. Nagatsu},
  title = {Purification of aromatic L-amino acid decarboxylase from bovine brain with a monoclonal antibody.},
  journal = {Biochemical Journal},
  year = 1988,
}

@article{CTT100706767,
  author = {N. Kaneda and H. Ichinose and K. Kobayashi and K. Oka and F. Kishi and A. Nakazawa and Y. Kurosawa and K. Fujita and T. Nagatsu},
  title = {Molecular cloning of cDNA and chromosomal assignment of the gene for human phenylethanolamine N-methyltransferase, the enzyme for epinephrine biosynthesis},
  journal = {Journal of Biological Chemistry},
  year = 1988,
}

@article{CTT100706817,
  author = {M. Naoi and H. Ichinose and T. Takahashi and T. Nagatsu},
  title = {Sensitive assay for determination of pyridoxal-5-phosphate in enzymes using high-performance liquid chromatography after derivatization with cyanide},
  journal = {Journal of Chromatography B: Biomedical Sciences and Applications},
  year = 1988,
}

@article{CTT100706757,
  author = {H. Ichinose and A. Togari and H. Suzuki and H. Kumagai and T. Nagatsu},
  title = {Increase of catecholamines in mouse brain by systemic administration of gamma-glutamyl L-3,4-dihydroxyphenylalanine.},
  journal = {Journal of Neurochemistry},
  year = 1987,
}

@article{CTT100706768,
  author = {N. Kaneda and K. Kobayashi and H. Ichinose and F. Kishi and A. Nakazawa and Y. Kurosawa and K. Fujita and T. Nagatsu},
  title = {Isolation of a novel cDNA clone for human tyrosine hydroxylase: Alternative RNA splicing produces four kinds of mRNA from a single gene},
  journal = {Biochemical and Biophysical Research Communications},
  year = 1987,
}

@article{CTT100706777,
  author = {K. Kobayashi and N. Kaneda and H. Ichinose and F. Kishi and A. Nakazawa and Y. Kurosawa and K. Fujita and T. Nagatsu},
  title = {Isolation of a full-length cDNA clone encoding human tyrosine hydroxylase type 3},
  journal = {Nucleic Acids Research},
  year = 1987,
}

@article{CTT100706869,
  author = {T. Terasaki and Y. Shimosato and T. Nakajima and M. Tsumuraya and H. Ichinose and T. Nagatsu and K. Kato},
  title = {Reversible squamous cell characteristics induced by vitamin A deficiency in a small cell lung cancer cell line},
  journal = {Cancer Research},
  year = 1987,
}

@article{CTT100706870,
  author = {T. Terasaki and Y. Shimosato and T. Nakajima and M. Tsumuraya and S. Morinaga and S. Hirohashi and K. Yamaguchi and K. Kato and H. Ichinose and T. Nagatsu},
  title = {CHANGES IN CELL CHARACTERISTICS DUE TO CULTURE CONDITIONS IN CELL-LINES FROM HUMAN SMALL-CELL LUNG-CANCER},
  journal = {Japanese Journal of Clinical Oncology},
  year = 1986,
}

@article{CTT100706814,
  author = {T. Nakajima and Y. Shimosato and S. Morinaga and T. Terasaki and M. Tsumuraya and K. Yamaguchi and H. Ichinose and T. Nagatsu and K. Kato and Y. Nakazato},
  title = {Immunohistochemical study of small cell lung carcinoma; with special reference to the neuroendocrine markers aromatic L-amino acid decarboxylase and gastrin-releasing peptide},
  journal = {Japanese Journal of Clinical Oncology},
  year = 1986,
}

@article{CTT100706807,
  author = {T. Nagatsu and H. Ichinose and K. Kojima and T. Kameya and J. Shimase and T. Kodama and Y. Shimosato},
  title = {Aromatic l-amino acid decarboxylase activities in human lung tissues: Comparison between normal lung and lung carcinomas},
  journal = {Biochemical medicine},
  year = 1985,
}

@article{CTT100706734,
  author = {H. Ichinose and K. Kojima and A. Togari and Y. Kato and S. Parvez and H. Parvez and T. Nagatsu},
  title = {Simple purification of aromatic l-amino acid decarboxylase from human pheochromocytoma using high-performance liquid chromatography},
  journal = {Analytical Biochemistry},
  year = 1985,
}

@article{CTT100706867,
  author = {T. Terasaki and T. Kameya and T. Nakajima and M. Tsumuraya and Y. Shimosato and K. Kato and H. Ichinose and T. Nagatsu and T. Hasegawa},
  title = {Interconversion of biological characteristics of small cell lung cancer depending on culture conditions},
  journal = {Gann, The Japanese Journal of Cancer Research},
  year = 1984,
}

@inproceedings{CTT100909300,
  author = {Haruka Kono and Satoshi Hara and Tadaomi Furuta and Hiroshi Ichinose},
  title = {Analysis of the binding profile of quinonoid-form of dihydropteridine to quinonoid-dihydropteridine reductase},
  booktitle = {},
  year = 2023,
}

@inproceedings{CTT100906078,
  author = {河野はるか and 原怜 and 古田忠臣 and 一瀬宏},
  title = {葉酸代謝とビオプテリン代謝の接点},
  booktitle = {},
  year = 2023,
}

@inproceedings{CTT100799508,
  author = {河野はるか and 原怜 and 古田忠臣 and 一瀬宏},
  title = {分子シミュレーションによるキノノイドジヒドロプテリジン還元酵素の基質認識機構の解析},
  booktitle = {},
  year = 2019,
}

@inproceedings{CTT100800123,
  author = {河野はるか and 古田忠臣 and 原怜 and 一瀬宏},
  title = {キノノイドジヒドロプテリジン還元酵素の基質認識機構の解析},
  booktitle = {},
  year = 2019,
}

@inproceedings{CTT100791782,
  author = {Hoshino, K. and Kimura, K. and Hayashi, M. and Nagao, Y. and Hachimori, K. and Terao, Y. and Kawahata, I. and Shintaku, H. and Hiroshi Ichinose},
  title = {Gene analysis of Segawa disease at the neurological clinic for children},
  booktitle = {JOURNAL OF THE NEUROLOGICAL SCIENCES},
  year = 2017,
}

@inproceedings{CTT100791775,
  author = {Kawahata, I. and Lai, Y. and Morita, J. and Kato, S. and Ohtaku, S. and Tomioka, Y. and Tabuchi, A. and Tsuda, M. and Sumi-Ichinose, C. and Kondo, K. and Izumi, Y. and Kume, T. and Akaike, A. and Ohashi, K. and Mizuno, K. and Hasegawa, K. and Hiroshi Ichinose and Kobayashi, K. and Yamakuni, T.},
  title = {V-1/CP complex formation is required for genetic co-regulation of adult nigrostriatal dopaminergic function via the RHO/MAL/SRF pathway in vitro and in vivo},
  booktitle = {JOURNAL OF THE NEUROLOGICAL SCIENCES},
  year = 2017,
}

@inproceedings{CTT100786212,
  author = {一瀬宏},
  title = {パーキンソン病患者脳脊髄液におけるプテリジン化合物の変化について},
  booktitle = {},
  year = 2017,
}

@inproceedings{CTT100753591,
  author = {一瀬宏 and 黒崎宏貴 and 荒川志信 and 渡邊祐貴 and 長谷川一子 and 横山照夫 and 堀内恵美子 and Jan O. Aasly},
  title = {遺伝性パーキンソン病Park8患者家系における脳脊髄液中ビオプテリン代謝の解析},
  booktitle = {ビタミン},
  year = 2017,
}

@inproceedings{CTT100791774,
  author = {Amagase, Harunobu and Hiroshi Ichinose and Kondo, Atsuo and Abe, Koichi and Watanabe, Toshiaki and Sueki, Kazuo and Shigeoka, Shigeru},
  title = {Continuous Efforts of the Vitamin Society of Japan to Increase Folate Intake in Japan},
  booktitle = {FASEB JOURNAL},
  year = 2016,
}

@inproceedings{CTT100791460,
  author = {一瀬宏},
  title = {8.フェニルケトン尿症における認知機能障害のメカニズム(第442回研究協議会研究発表要旨,ビタミンB研究委員会)},
  booktitle = {ビタミン},
  year = 2016,
}

@inproceedings{CTT100791416,
  author = {一瀬宏},
  title = {6. ビオプテリンの生理機能と代謝に関する新しい知見(ビタミン・バイオファクターの生理機能に関する最新の話題,シンポジウム(平成26年度),ビタミンB研究委員会)},
  booktitle = {ビタミン},
  year = 2015,
}

@inproceedings{CTT100791300,
  author = {徐 峰 and 嶋口 翔 and 実近 翔 and 本田 俊一郎 and 中田 理恵子 and 一瀬宏},
  title = {8.ビオプテリン代謝と葉酸代謝の接点について(第435回研究協議会研究発表要旨,ビタミンB研究委員会)},
  booktitle = {ビタミン},
  year = 2014,
}

@inproceedings{CTT100791673,
  author = {一瀬宏 and 本間 大悟 and 一瀬 鷲見 千穂 and 近藤 一直},
  title = {モノアミン・ビオプテリン代謝改変マウスを用いたモノアミンニューロンの制御機構と発達変化の解析},
  booktitle = {自律神経 = The Autonomic nervous system},
  year = 2013,
}

@inproceedings{CTT100791280,
  author = {一瀬宏},
  title = {ビオプテリンの生理機能と病態代謝(学会賞受賞講演,第65回大会講演要旨)},
  booktitle = {ビタミン},
  year = 2013,
}

@inproceedings{CTT100791282,
  author = {一瀬宏 and 岩下 由佳 and 宗実 悠佳 and 徳岡 宏文 and 村松 慎一},
  title = {7.チロシン水酸化酵素過剰発現による神経終末でのドーパミン量への影響(第431回研究協議会研究発表要旨,ビタミンB研究委員会)},
  booktitle = {ビタミン},
  year = 2013,
}

@inproceedings{CTT100706730,
  author = {H. Ichinose and D. Homma and C. Sumi-Ichinose and T. Nomura and K. Kondo},
  title = {GTP cyclohydrolase regulation. Implications for brain development and function.},
  booktitle = {Advances in Pharmacology},
  year = 2013,
}

@inproceedings{CTT100791776,
  author = {Abe, J. and Nishikomori, R. and Izawa, K. and Kawai, T. and Yasumi, T. and Mitsuiki, N. and Ohara, O. and Toyoshima, I. and Hasegawa, K. and Hiroshi Ichinose and Heike, T.},
  title = {GENETIC ANALYSIS OF AICARDI-GOUTIERES SYNDROME IN JAPAN},
  booktitle = {JOURNAL OF CLINICAL IMMUNOLOGY},
  year = 2012,
}

@inproceedings{CTT100791777,
  author = {Lai, Yanxin and Jin, Jingmei and Kawahata, Ichiro and Morita, Junichi and Fukunaga, Kohji and Hiroshi Ichinose and Yamakuni, Tohru},
  title = {A novel regulatory mechanism of tyrosine hydroxylase gene expression via a new actin cytoskeleton formation enhancer (V-1)/DLK 1/notch 1-mediated signaling in murine adrenal chromaffin cells},
  booktitle = {JOURNAL OF PHARMACOLOGICAL SCIENCES},
  year = 2012,
}

@inproceedings{CTT100791771,
  author = {Kawahata, Ichiro and Morita, Junichi and Tabuchi, Akiko and Tsuda, Masaaki and Hiroshi Ichinose and Izumi, Yasuhiko and Kume, Toshiaki and Akaike, Akinori and Yamakuni, Tohru},
  title = {V-1 regulates tyrosine hydroxylase gene expression via SRF-mediated transcription coupled with actin polymerization},
  booktitle = {JOURNAL OF PHARMACOLOGICAL SCIENCES},
  year = 2012,
}

@inproceedings{CTT100791583,
  author = {一瀬宏 and 徐 峰 and 原 慶賢 and 嶋口 翔 and 実近 翔},
  title = {7.ビオプテリン量調節における再還元反応の寄与について(第429回研究協議会研究発表要旨,ビタミンB研究委員会)},
  booktitle = {ビタミン},
  year = 2012,
}

@inproceedings{CTT100791770,
  author = {Chiken, Satomi and Sumi-Ichinose, Chiho and Hiroshi Ichinose and Kondo, Kazunao and Nambu, Atsushi},
  title = {Neuronal activity of the basal ganglia in a transgenic mouse model of dopa-responsive dystonia},
  booktitle = {NEUROSCIENCE RESEARCH},
  year = 2011,
}

@inproceedings{CTT100791779,
  author = {Ohkuma, Mahito and Kawai, Fusao and Horiguchi, Masayuki and Hiroshi Ichinose and Miyachi, Ei-ichi},
  title = {A type of the human retinal bipolar cell expresses the type II sodium channel},
  booktitle = {NEUROSCIENCE RESEARCH},
  year = 2011,
}

@inproceedings{CTT100791780,
  author = {Tokuoka, Hirofumi and Muramatsu, Shin-ichi and Ichinose, Chiho and Metzger, Daniel and Hiroshi Ichinose},
  title = {Trans-axonal compensation of dopamine in the nigrostriatal dopaminergic projection},
  booktitle = {NEUROSCIENCE RESEARCH},
  year = 2011,
}

@inproceedings{CTT100791783,
  author = {Hatanaka, Takayuki and Hatanaka, Yasuhito and Ito, Takehito and Igarashi, Hiroyuki and Tokuoka, Hirofumi and Muramatsu, Shin-ichi and Endo, Tsuyoshi and Hirosaki, Ken and Takasaki, Akihiko and nobuhiro hayashi and Metzger, Daniel and Hiroshi Ichinose},
  title = {Generation of transgenic mice to analyze the role of Nurr1 and Nur77 genes in the adult brain},
  booktitle = {NEUROSCIENCE RESEARCH},
  year = 2011,
}

@inproceedings{CTT100791473,
  author = {堀口 美恵子 and 福田 早苗 and 一瀬宏 and 中富 康仁 and 山口 浩二 and 倉恒 弘彦 and 渡辺 恭良},
  title = {10.慢性疲労症候群患者におけるGTPシクロヒドロラーゼI遺伝子多型の解析(第425回研究協議会研究発表要旨,ビタミンB研究委員会)},
  booktitle = {ビタミン},
  year = 2011,
}

@inproceedings{CTT100791548,
  author = {一瀬宏 and 本間 大悟 and 徳岡 宏文 and 加藤 節子},
  title = {2.ビオプテリン欠乏マウスにおける生後発達期におけるモノアミンの変化(第420回研究協議会研究発表要旨,ビタミンB研究委員会)},
  booktitle = {ビタミン},
  year = 2010,
}

@inproceedings{CTT100791579,
  author = {一瀬宏 and 実近 翔 and 須藤 雄介},
  title = {10.ジヒドロプテリジン還元酵素ノックアウトマウスにおけるモノアミン代謝の変化(第418回研究協議会研究発表要旨,ビタミンB研究委員会)},
  booktitle = {ビタミン},
  year = 2010,
}

@inproceedings{CTT100791773,
  author = {Homma, Daigo and Tokuoka, Hirofumi and Katoh, Setsuko and Hiroshi Ichinose},
  title = {Alterations in the monoamines and the synthesizing enzymes in the postnatal developmental period of the brain of Spr(-/-) mice},
  booktitle = {NEUROSCIENCE RESEARCH},
  year = 2010,
}

@inproceedings{CTT100791781,
  author = {Tokuoka, Hirofumi and Muramatsu, Shin-ichi and Hiroshi Ichinose},
  title = {Compenensatory regulation of dopamine content in the nigro-striatal dopaminergic projection},
  booktitle = {NEUROSCIENCE RESEARCH},
  year = 2010,
}

@inproceedings{CTT100593279,
  author = {一瀬宏 and 川畑伊知郎},
  title = {プロテアゾーム阻害によるリン酸化チロシン水酸化酵素の不溶性凝集体形成と生理的意義},
  booktitle = {ビタミン},
  year = 2009,
}

@inproceedings{CTT100593537,
  author = {Ichiro Kawahata and Hiroshi Ichinose},
  title = {Phosphorylated tyrosine hydroxylase formed insoluble aggregates by inhibition of ubiquitin proteasome system in NGF-differentiated PC12D cells},
  booktitle = {Pteridines},
  year = 2009,
}

@inproceedings{CTT100593534,
  author = {Ichiro Kawahata and Hiroshi Ichinose},
  title = {Long-term up-regulation of the level of phosphorylated tyrosine hydroxylase by depletion of dopamine or biopterin},
  booktitle = {Neuroscience Research},
  year = 2009,
}

@inproceedings{CTT100593284,
  author = {Hiroshi Ichinose and Chiho Ichinose and Ichiro Kawahata and Takahide Nomura},
  title = {Regulation of dopaminergic neural transmission by the amount of the TH protein at nerve terminals},
  booktitle = {Journal of Phamacological Sciences},
  year = 2009,
}

@inproceedings{CTT100593282,
  author = {Ichiro Kawahata and Saburo Yagishita and Kazuko Hasegawa and Ikuko Nagatsu and Toshiharu Nagatsu and Hiroshi Ichinose},
  title = {Formation of insoluble aggregates of phosphorylated tyrosine hydroxylase after proteasomal inhibition in PC12D cells},
  booktitle = {Movement Disorders},
  year = 2008,
}

@inproceedings{CTT100593283,
  author = {Hiroshi Ichinose and Ichiro Kawahata and Wataru Sato and Kazuaki Mizuno and Yoshiro Kurabayashi and Itaru Toyoshima and Saburo Yagishita and Kazuko Hasegawa},
  title = {Developmental Alterations of LRRK2 in the Mouse Brain},
  booktitle = {Movement Disorders},
  year = 2008,
}

@inproceedings{CTT100590939,
  author = {Ichiro Kawahata and Saburo Yagishita and Kazuko Hasegawa and Ikuko Nagatsu and Toshiharu Nagatsu and Hiroshi Ichinose},
  title = {Dopamine-synthesizing enzymes formed intracellular inclusions after proteasomal inhibition in PC12D cells},
  booktitle = {Progress in Medicine},
  year = 2008,
}

@inproceedings{CTT100593535,
  author = {Ichiro Kawahata and Saburo Yagishita and Kazuko Hasegawa and Ikuko Nagatsu and Toshiharu Nagatsu and Hiroshi Ichinose},
  title = {Formation  of  insoluble  aggregates  of  phosphorylated tyrosine hydroxylase after proteasomal inhibition in PC12D cells},
  booktitle = {Neuroscience Research},
  year = 2008,
}

@inproceedings{CTT100593449,
  author = {川畑伊知郎 and 一瀬 宏},
  title = {リン酸化されたチロシン水酸化酵素のユビキチン プロテアソーム系による分解とその凝集特性},
  booktitle = {生化学},
  year = 2008,
}

@inproceedings{CTT100706743,
  author = {H. Ichinose and T. Nagatsu and C. Sumi-Ichinose and T. Nomura},
  title = {Dopa-Responsive Dystonia},
  booktitle = {Genetics of Movement Disorders},
  year = 2003,
}

@inproceedings{CTT100706800,
  author = {T. Nagatsu and H. Ichinose},
  title = {Genetic Basis of Dominant Dystonia},
  booktitle = {Advances in Pharmacology},
  year = 1997,
}

@inproceedings{CTT100706810,
  author = {T. Nagatsu and K. Kobayashi and H. Ichinose},
  title = {Alterations in catecholamine system enzymes},
  booktitle = {Annals of the New York Academy of Sciences},
  year = 1995,
}

@misc{CTT100791325,
  author = {西小森 隆太 and 阿部 純也 and 井澤 和司 and 河合 朋樹 and 八角 高裕 and 満生 紀子 and 小原 收 and 豊島 至 and 長谷川 一子 and 一瀬宏 and 平家 俊男},
  title = {P1-004  本邦におけるAicardi-Goutières症候群の遺伝子解析},
  year = 2012,
}

@misc{CTT100595129,
  author = {Hiroshi Ichinose},
  title = {Effects of Heterocyclic Amines in Food on Dopamine Metabolism in Nigro-striatal Dopaminergic Neurons.  },
  year = 1989,
}

@misc{CTT100831057,
  author = {一瀬宏 and 原怜 and 吉田　勇輝 and 村松　慎一 and 加藤　節子},
  title = {ＳＰＲをコードするポリヌクレオチドを含む組み換えベクター、及びそれを含む組成物},
  howpublished = {公開特許},
  year = 2020,
  month  = {},
  note   = {特願2018-206643(2018/11/01), 特開2020-068734(2020/05/07)}
}




@phdthesis{CTT100595129,
  author = {Hiroshi Ichinose},
  title = {Effects of Heterocyclic Amines in Food on Dopamine Metabolism in Nigro-striatal Dopaminergic Neurons.  },
  school = {名古屋大学},
  year = 1989,
}