@book{CTT100830021, author = {半田宏 and 山口雄輝}, title = {新しい遺伝子工学 新版}, publisher = {朝倉書店}, year = 2014, } @book{CTT100691752, author = {坂本聡 and 半田宏}, title = {技術予測レポート2023 上巻 「健康寿命の延伸を目指す」日本の技術編}, publisher = {日本能率協会総合研究所, ソレカラ社}, year = 2013, } @book{CTT100691754, author = {半田宏 and 加部泰明 and 末松誠}, title = {見つける、量る、可視化する! 質量分析実験ガイド〜ライフサイエンス・医学研究で役立つ機器選択、サンプル調製、分析プロトコールのポイント}, publisher = {羊土社}, year = 2013, } @book{CTT100691755, author = {西尾広介 and 坂本聡 and 宇賀均 and 倉森見典 and 半田宏}, title = {磁性ビーズのバイオ・環境技術への応用展開(普及版)}, publisher = {シーエムシー出版}, year = 2012, } @book{CTT100691756, author = {壷内信吾 and 池田森人 and 成松宏樹 and 半田宏}, title = {ソフトナノテクノロジーにおける材料開発(普及版)}, publisher = {シーエムシー出版}, year = 2011, } @book{CTT100691757, author = {畠山士 and 半田宏}, title = {ナノ融合による先進バイオデバイス}, publisher = {シーエムシー出版}, year = 2011, } @book{CTT100691758, author = {畠山士 and 加部泰明 and 半田宏}, title = {ナノ粒子分散系の基礎と応用}, publisher = {シーエムシー出版}, year = 2011, } @book{CTT100691760, author = {Masaaki Kawano and Li Xing and Kit S. Lam and Hiroshi Handa and Tatsuo Miyamura and Susan Barnett and Indresh K. Srivastava and R. Holland Cheng}, title = {Development of Vaccines: From Discovery to Clinical Testing}, publisher = {Wiley}, year = 2011, } @book{CTT100691761, author = {西尾広介 and 池田森人 and 成松宏樹 and 壺内信吾 and 郷右近展之 and 半田宏}, title = {医療分野における材料と機能膜(普及版)}, publisher = {シーエムシー出版}, year = 2011, } @book{CTT100691763, author = {Masanori Abe and Hiroshi Handa}, title = {Biocompatible Nanomaterials: Synthesis, Characterization and Applications}, publisher = {Nova Science Pub Inc}, year = 2010, } @book{CTT100614930, author = {半田宏 and 畠山士}, title = {コアシェル微粒子の設計・合成技術・応用の展開}, publisher = {シーエムシー出版}, year = 2010, } @book{CTT100691764, author = {壺内信吾 and 西尾広介 and 池田森人 and 成松宏樹 and 郷右近展之 and 半田宏}, title = {ナノ粒子・マイクロ粒子の調製と応用技術(普及版)}, publisher = {シーエムシー出版}, year = 2010, } @book{CTT100691765, author = {半田宏 and 伊藤武彦 and 岩崎博史 and 岡田典弘 and 岸本健雄 and 工藤明 and 白髭克彦 and 田中幹子 and 徳永万喜洋 and 広瀬茂久 and 村上聡 and 菊池韶彦}, title = {ハートウェル遺伝学-遺伝子、ゲノム、そして生命システムへ-}, publisher = {メディカルサイエンスインターナショナル}, year = 2010, } @book{CTT100614921, author = {Yasuaki Kabe and Mamoru Hatakeyama and Satoshi Sakamoto and KOSUKE NISHIO and Hiroshi Handa}, title = {Novel Applications of Affinity Beads}, publisher = {Jhon Wiley & Sons. Inc.}, year = 2009, } @book{CTT100614928, author = {半田宏 and 和田忠士 and 坂本聡}, title = {診断学、1.MEMSと診断 他}, publisher = {株式会社テクノシステム}, year = 2009, } @book{CTT100832491, author = {山口雄輝 and 半田宏}, title = {転写制御とエピジェネティクス—ゲノムデコードに向けて}, publisher = {南山堂}, year = 2008, } @book{CTT100529111, author = {Sophie Delehouzee and 山口雄輝 and 半田宏}, title = {ヒトの分子生物学}, publisher = {丸善株式会社}, year = 2006, } @book{CTT100529114, author = {中村栄一 and 濱口宏夫 and 半田宏}, title = {化学の明日を考える}, publisher = {化学}, year = 2006, } @book{CTT100529119, author = {加部泰明 and 坂本聡 and 半田宏}, title = {タンパク質を操るビーズ技術}, publisher = {バイオニクス}, year = 2006, } @book{CTT100529122, author = {半田 宏}, title = {東京工業大学21世紀COEプログラム 生命工学フロンティアシステム}, publisher = {化学と工業}, year = 2006, } @book{CTT100529131, author = {半田宏 and 阿部正紀}, title = {機能性磁性ビーズの構築とバイオテクノロジーへの応用(2)}, publisher = {ライフサイエンスニュースレター 日本語版}, year = 2006, } @book{CTT100542245, author = {半田宏 and 和田忠士 and 山口雄輝}, title = {転写研究集中マスター}, publisher = {羊土社}, year = 2006, } @book{CTT100529109, author = {半田宏}, title = {ナノ粒子分散系の化学と技術}, publisher = {シーエムシー出版}, year = 2006, } @book{CTT100529134, author = {半田宏}, title = {新しい遺伝子工学}, publisher = {昭晃堂}, year = 2006, } @book{CTT100529138, author = {半田宏 and 阿部正紀 and 野田紘憙}, title = {磁性ビーズのバイオ・環境技術への応用展開}, publisher = {シーエムシー出版}, year = 2006, } @book{CTT100529148, author = {野村祥太郎 and 望月勇輔 and 西尾広介 and 坂本聡 and 半田宏}, title = {ナノ磁性微粒子による遺伝子導入法}, publisher = {遺伝子医学MOOK}, year = 2006, } @book{CTT100408852, author = {半田宏 and 阿部正紀}, title = {機能性磁性ビーズの構築とバイオテクノロジーへの応用(1)}, publisher = {ライフサイエンスニュースレター 日本語版第3号}, year = 2005, } @book{CTT100408853, author = {川野雅章 and 金刺進之介 and 高橋陵宇 and 井上隆昌 and 半田宏}, title = {DDS研究の現状と将来展望}, publisher = {PHARM TECH JAPAN}, year = 2005, } @book{CTT100408854, author = {半田宏 共訳}, title = {バイオテク用語辞典}, publisher = {東京化学同人}, year = 2005, } @book{CTT100408859, author = {郷右近展之 and 半田宏}, title = {機能性ナノ磁気ビ-ズの構築とバイオテクノロジ-への応用}, publisher = {未来材料}, year = 2005, } @book{CTT100408857, author = {壷内信吾 and 池田森人 and 成松宏樹 and 半田宏}, title = {ソフトナノテクノロジー‐バイオマテリアル革命‐}, publisher = {シ-エムシ-出版}, year = 2005, } @book{CTT100408856, author = {加部泰明 and 平尾聡 and 半田宏}, title = {ナノテクノロジ-の医学への応用-アフィニティナノ粒子を用いた医薬開発の応用展開-}, publisher = {炎症と免疫}, year = 2005, } @book{CTT100408855, author = {半田宏 共著}, title = {医療機器と再生医療―開発最前線と今後の動向―}, publisher = {情報機構}, year = 2005, } @book{CTT100388485, author = {半田 宏 and 阿部正紀 and 郷右近展之 and 西尾広介}, title = {バイオ・医療を志向する次世代の磁性微粒子}, publisher = {シーエムシー出版}, year = 2004, } @book{CTT100388472, author = {川口春馬 and 杉本忠夫 and 山本孝夫 and 岩村武 and 中條善樹 and 福井寛 and 菊地隆司 and 星川豊久 and 江口浩一 and 藤正督 and 澤上一美 and 田島秀二 and 今岡享稔 and 山元公寿 and 鳥越幹二郎 and 江角邦男 and 長井勝利 and 半田宏}, title = {ナノ粒子・マイクロ粒子の最先端技術}, publisher = {シーエムシー出版}, year = 2004, } @book{CTT100388503, author = {宮崎榮三 and 猪飼篤 and 岩本光正 and 髙柳邦夫 and 福井賢一 and 和田昭英 and 枝元一之 and 鯉沼秀臣 and 間中孝彰 and 梶川浩太郎 and 池田富樹 and 渡辺順次 and 竹添秀男 and 半那純一 and 半田宏 and 跡部真人 and 大坂武男 and 半田宏}, title = {表面科学の基礎と応用}, publisher = {エヌ・ティー・エス}, year = 2004, } @book{CTT100483648, author = {半田宏 共訳}, title = {「ゲノム 2」村松正實 監訳}, publisher = {メディカル・サイエンス・インターナショナル}, year = 2003, } @book{CTT100483639, author = {半田宏}, title = {アフィニティナノビーズの構築と創薬への応用 Bioベンチャー}, publisher = {羊土社}, year = 2003, } @book{CTT100487952, author = {半田宏 川口春馬}, title = {ナノアフィニティビーズのすべて}, publisher = {中山書店}, year = 2003, } @book{CTT100480788, author = {長谷川慎 and 半田宏}, title = {ポストゲノムシークエンス時代の細胞内タンパク質複合体ネットワークの解析、化学}, publisher = {(株)化学同人}, year = 2002, } @book{CTT100480787, author = {半田宏 共著:小泉光惠 and 奥山喜久夫 and 目 義雄 編集}, title = {ナノ粒子の製造・評価・応用・機器の最新技術}, publisher = {Recent Advamces in Nano Power Technology-Preparation,Evaluation,Utilization and Equipments- (株)シーエムシー出版}, year = 2002, } @book{CTT100466431, author = {半田 宏 編集 and 山口雄輝 共著}, title = {転写がわかる -基本転写から発生、再生、先端医療まで-}, publisher = {羊土社}, year = 2002, } @book{CTT100466432, author = {半田 宏 共著 and 柳田 博明 監修}, title = {微粒子工学大系 第ニ巻 応用技術}, publisher = {フジ・テクノシステム}, year = 2002, } @book{CTT100480786, author = {半田 宏}, title = {サイエンスは個性&プライド}, publisher = {MEDCHEM NEWS 、社)日本薬学会}, year = 2002, } @book{CTT100452253, author = {半田宏}, title = {「NAVIGATOR -Vascular Biologyナビゲーター‐」}, publisher = {メディカルレビュー社}, year = 2001, } @book{CTT100452252, author = {半田宏 and 古谷利夫 and 増保安彦 and 辻本豪三}, title = {「ゲノム創薬-創薬のパラダイム-」}, publisher = {中山書店}, year = 2001, } @book{CTT100452251, author = {半田宏 共著}, title = {「基礎生化学実験法 第3巻 タンパク質Ⅱ 機能・動態解析法」日本生化学会編}, publisher = {東京化学同人}, year = 2001, } @book{CTT100454465, author = {半田宏 共著}, title = {「転写因子と疾患」村松正實 編集}, publisher = {医歯薬出版株式会社}, year = 2001, } @book{CTT100438304, author = {石井俊輔 and 加藤茂明 and 半田宏 and 藤井義明 and 山本雅之}, title = {転写因子の機能}, publisher = {蛋白質核酸酵素 増刊}, year = 2000, } @book{CTT100438302, author = {半田宏 and 川口春馬 and 松本史朗他}, title = {微粒子・粉体の最先端技術}, publisher = {株式会社シーエムシー}, year = 2000, } @book{CTT100438274, author = {半田宏 and 石井俊輔 and 山本雅之 and 藤井義明}, title = {ゲノムからの情報発現}, publisher = {シュプリンガー・フェアラーク東京株式会社}, year = 2000, } @book{CTT100438339, author = {HIROSHI HANDA}, title = {Real-Time Analysis of Biomolecular Interactions:Applications of BIACORE}, publisher = {Springer}, year = 2000, } @book{CTT100430133, author = {H.Handa and Y.Yamaguchi& T.Wada}, title = {Purification of DNA binding proteins High Resolution Chromatography: A Practical Approach}, publisher = {Oxford University Press}, year = 1999, } @book{CTT100430137, author = {T.Wada and T.Takagi and Y.Yamaguchi and K.Kawase and M.Hiraomoto and A.Ferdous and M.Takayama and K.A.W.Lee and H.C.Hurst and H.Handa}, title = {Copurification of casein kinase II with transcription factor ATF/E4TF3}, publisher = {Alternation of Transcription by DNA Tumor Virus Proteins}, year = 1999, } @book{CTT100431689, author = {半田宏}, title = {細胞機能と代謝マップ II. 細胞の動的機能}, publisher = {東京化学同人}, year = 1999, } @book{CTT100431690, author = {半田宏}, title = {環境ホルモン汚染対策-測定・評価から企業対策まで-}, publisher = {株式会社 エヌ・ティ-・エス}, year = 1999, } @book{CTT100431693, author = {半田宏共著}, title = {新遺伝子工学ハンドブック}, publisher = {羊土社}, year = 1999, } @book{CTT100431694, author = {半田宏}, title = {Bio Science新用語ライブラリ-、転写因子、第2版}, publisher = {羊土社}, year = 1999, } @book{CTT100433614, author = {半田 宏}, title = {転写因子研究1999-基本転写因子・フロマチニ制御から医学研究まで-;()}, publisher = {羊土社}, year = 1999, } @book{CTT100428979, author = {半田宏}, title = {「生化学辞典」第3版}, publisher = {東京化学同人}, year = 1998, } @book{CTT100547739, author = {日本化学学会 編 and 半田宏}, title = {「細胞機能と代謝マップII. 細胞の動的機能」}, publisher = {東京化学同人}, year = 1998, } @book{CTT100428980, author = {永田和宏 and 半田宏 共編}, title = {「生体物質相互作用のリアルタイム解析実験法」}, publisher = {シュプリンガ-・フェアラ-ク東京}, year = 1998, } @book{CTT100411783, author = {半田宏}, title = {転写因子研究の最前線'97}, publisher = {羊士社}, year = 1997, } @book{CTT100411798, author = {半田宏}, title = {遺伝子診療}, publisher = {医学書院}, year = 1997, } @book{CTT100411796, author = {半田宏}, title = {わかりやすい遺伝子工学}, publisher = {昭晃堂}, year = 1997, } @book{CTT100411794, author = {HIROSHI HANDA}, title = {Affinity latex for DNA diagnosis}, publisher = {Advances in Polymer Biomaterials}, year = 1997, } @book{CTT100411782, author = {半田宏}, title = {新遺伝子工学ハンドブック}, publisher = {羊士社}, year = 1996, } @book{CTT100411780, author = {半田宏}, title = {転写因子,生物機能調節の要}, publisher = {共立出版株式会社}, year = 1996, } @book{CTT100411781, author = {半田宏}, title = {転写のしくみと疾患}, publisher = {羊士社}, year = 1996, } @book{CTT100411777, author = {半田宏}, title = {Bio Science用語ライブラリー,転写因子}, publisher = {羊士社}, year = 1995, } @book{CTT100411756, author = {HIROSHI HANDA}, title = {DNA affinity chromatography}, publisher = {Methods in Enzymology}, year = 1995, } @book{CTT100411755, author = {HIROSHI HANDA}, title = {Preparation of DNA-carrying affinity latex and purification of transcription factor with the latex.}, publisher = {Polymer Biomaterials in Solution, as interfaces and as Solids.}, year = 1995, } @book{CTT100411749, author = {半田宏}, title = {分子生物学プロトコール}, publisher = {南江堂}, year = 1994, } @book{CTT100411728, author = {半田宏}, title = {ウイルス感染症の臨床と病理}, publisher = {医学書院}, year = 1991, } @book{CTT100411729, author = {半田宏}, title = {遺伝子の発現と制御II}, publisher = {丸善株式会社}, year = 1990, } @article{CTT100811795, author = {Tatsuya Onishi and Sachiko Matsuda and Yuki Nakamura and Junko Kuramoto and Akinori Tsuruma and Satoshi Sakamoto and Shunichi Suzuki and Daiichiro Fuchimoto and Akira Onishi and Shinichi Chikaki and Miki Kaneko and Akihiro Kuwahata and Masaki Sekino and Hiroshi Yasuno and Naohiro Hanyu and Tomoko Kurita and Hiroyuki Takei and Takashi Sakatani and Kanae Taruno and Seigo NakamuraTetsu Hayashida and Hiromitsu Jinno and Moriaki Kusakabe and Hiroshi Handa and Kaori Kameyama and Yuukou Kitagawa}, title = {Magnetically-promoted rapid immunofluorescence staining for frozen tissue sections.}, journal = {J. Histochem. Cytochem.}, year = 2019, } @article{CTT100782291, author = {Kimura A. and Kitajima, M. and Nishida, K. and Serada, S. and Fujimoto, M. and Naka, T. and Fujii-Kuriyama, Y. and Satoshi Sakamoto and Takumi Ito and HIROSHI HANDA and Tanaka, T. and Yoshimura, A and Suzuki, H.}, title = {NQO1 inhibits TLR-dependent production of selective cytokines by promoting PDLIM2-mediated degradation of IkB-z}, journal = {J. Exp. Med.}, year = 2018, } @article{CTT100779857, author = {Tomoyuki Mori and Takumi Ito and Shujie Liu and Hideki Ando and Satoshi Sakamoto and Yuki Yamaguchi and Etsuko Tokunaga and Norio Shibata and Hiroshi Handa}, title = {Structural basis of thalidomide enantiomer binding to cereblon}, journal = {Scientific Reports}, year = 2018, } @article{CTT100723495, author = {Yasuaki Kabe and Takanori Nakane and Ikko Koike and Tatsuya Yamamoto and Yuki Sugiura and Erisa Harada and Kenji Sugase and Tatsuro Shimamura and Mitsuyo Ohmura and Kazumi Muraoka and Ayumi Yamamoto and Takeshi Uchida and So Iwata and Yuki Yamaguchi and Elena Krayukhina and Masanori Noda and Hiroshi Handa and Koichiro Ishimori and Susumu Uchiyama and Takuya Kobayashi and Makoto Suematsu}, title = {Haem-dependent dimerization of PGRMC1/sigma-2 receptor facilitates cancer proliferation and chemoresistance}, journal = {Nat. Commun.}, year = 2016, } @article{CTT100782329, author = {Pérez-Perarnau, A. and Preciado, S. and Palmeri, C. M. and Moncunill-Massaguer, C. and Iglesias-Serret, D. and González-Gironès, D. M. and Miguel, M. and Satoki Karasawa and Sakamoto, S and Cosialls, A. M. and Rubio-Patiño, C. and Saura-Esteller, J. and Ramón, R. and Caja, L. and Fabregat, I. and Pons, G. and HIROSHI HANDA and Albericio, F. and Gil, J. and Lavilla, R.}, title = {A trifluorinated thiazoline scaffold leading to pro-apoptotic agents targeting prohibitins}, journal = {Angew. Chem. Int. Ed.}, year = 2014, } @article{CTT100723499, author = {Junichi Yamamoto and Yuri Hagiwara and Kunitoshi Chiba and Tomoyasu Isobe and Takashi Narita and Hiroshi Handa and Yuki Yamaguchi}, title = {DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes.}, journal = {Nat. Commun.}, year = 2014, } @article{CTT100723500, author = {Misao Takemoto and Yumi Kawamura and Mikako Hirohama and Yuki Yamaguchi and Hiroshi Handa and Hisato Saitoh and Yoichi Nakao and Manabu Kawada and Khan Khalid and Hiroyuki Koshino and Ken-ichi Kimura and Akihiro Ito and Minoru Yoshida}, title = {Inhibition of protein SUMOylation by davidiin, an ellagitannin from Davidia involucrata}, journal = {J. Antibiot.}, year = 2014, } @article{CTT100723501, author = {Satoshi Sakamoto and Kenshi Omagari and Yoshinori Kita and Yusuke Mochizuki and Yasuyuki Naito and Shintaro Kawata and Sachiko Matsuda and Osamu Itano and Hiromitsu Jinno and Hiroya Takeuchi and Yuki Yamaguchi and Yuko Kitagawa and Hiroshi Handa}, title = {Magnetically Promoted Rapid Immunoreactions Using Functionalized Fluorescent Magnetic Beads: A Proof of Principle}, journal = {Clinical Chemistry}, year = 2014, } @article{CTT100691776, author = {Shuji Iida and Kensuke Imai and Sachiko Matsuda and Osamu Itano and Mamoru Hatakeyama and Satoshi Sakamoto and Daisuke Kokuryo and Koji Okabayashi and Takashi Endo and Yoshiyuki Ishii and Hirotoshi Hasegawa and Ichio Aoki and Hiroshi Handa and Yuko Kitagawa}, title = {In vivo identification of sentinel lymph nodes using MRI and size-controlled and monodispersed magnetite nanoparticles}, journal = {Journal of Magnetic Resonance Imaging}, year = 2013, } @article{CTT100691775, author = {Hitomi Miyazaki and Ken Higashimoto and Yukari Yada and Takaho A. Endo and Jafar Sharif and Toshiharu Komori and Masashi Matsuda and Yoko Koseki and Manabu Nakayama and Hidenobu Soejima and Hiroshi Handa and Haruhiko Koseki and Susumu Hirose and Kenichi Nishioka}, title = {Ash1l Methylates Lys36 of Histone H3 Independently of Transcriptional Elongation to Counteract Polycomb Silencing}, journal = {PLoS Genet}, year = 2013, } @article{CTT100691772, author = {Vipul Gupta and Shujie Liu and Hideki Ando and Ryohei Ishii and Shumpei Tateno and Yuki Kaneko and Masato Yugami and Satoshi Sakamoto and Yuki Yamaguchi and Osamu Nureki and Hiroshi Handa}, title = {Salicylic acid induces mitochondrial injury by inhibiting ferrochelatase heme biosynthesis activity}, journal = {Mol. Pharmacol.}, year = 2013, } @article{CTT100691770, author = {Kaoru Ohno and Jun-ichi Sawada and Shigeharu Takiya and Mai Kimoto and Akiko Matsumoto and Takuya Tsubota and Keiro Uchino and Chi-chung Hui and Hideki Sezutsu and Hiroshi Handa and Yoshiaki Suzuki}, title = {Silk Gland Factor-2, Involved in Fibroin Gene Transcription, Consists of LIM Homeodomain, LIM-interacting, and Single-stranded DNA-binding Proteins}, journal = {J. biol. chem}, year = 2013, } @article{CTT100723504, author = {Teruya Enomoto and Masa-aki Kawano and Hajime Fukuda and Wataru Sawada and Takamasa Inoue and Kok Chee Haw and Yoshinori Kita and Satoshi Sakamoto and Yuki Yamaguchi and Takeshi Imai and Mamoru Hatakeyama and Shigeyoshi Saito and Adarsh Sandhu and Masanori Matsui and Ichio Aoki and Hiroshi Handa}, title = {Viral protein-coating of magnetic nanoparticles using simian virus 40 VP1}, journal = {J. Biotechnol.}, year = 2013, } @article{CTT100691778, author = {Teruya Enomoto and Masaaki Kawano and Hajime Fukuda and Wataru Sawada and Takamasa Inoue and Kok Chee Haw and Yoshinori Kita and Satoshi Sakamoto and Takeshi Imai and Mamoru Hatakeyama and Shigeyoshi Saito and Adarsh Sandhu and Masanori Matsui and Ichio Aoki and Hiroshi Handa}, title = {Viral protein-coating of magnetic nanoparticles using simian virus 40 VP1}, journal = {Journal of Biotechnology}, year = 2013, } @article{CTT100691779, author = {Jinsuk Kang and Zuolian Shen and Jae-Min Lim and Hiroshi Handa and Lance Wells and Dean Tantin}, title = {Regulation of Oct1/Pou2f1 transcription activity by O-GlcNAcylation}, journal = {The FASEB Journal}, year = 2013, } @article{CTT100691780, author = {Kentaro Hotta and Akihiro Nashimoto and Eiji Yasumura and Masafumi Suzuki and Motoki Azuma and Yosuke Iizumi and Daisuke Shima and Ryusuke Nabeshima and Masaki Hiramoto and Akira Okada and Kumiko Sakata-Sogawa and Makio Tokunaga and Takumi Ito and Hideki Ando and Satoshi Sakamoto and Yasuaki Kabe and Shinichi Aizawa and Takeshi Imai and Yuki Yamaguchi and Hajime Watanabe and Hiroshi Handa}, title = {Vesnarinone suppresses TNFα mRNA expression by inhibiting valosin-containing protein}, journal = {Mol. Pharmacol.}, year = 2013, } @article{CTT100691782, author = {Jeff Kershaw and Christoph Leuze and Ichio Aoki and Takayuki Obata and Iwao Kanno and Hiroshi Ito and Yuki Yamaguchi and Hiroshi Handa}, title = {Systematic changes to the apparent diffusion tensor of in vivo rat brain measured with an oscillating-gradient spin-echo sequence}, journal = {Neuroimage}, year = 2013, } @article{CTT100691783, author = {Satoki Karasawa and Motoki Azuma and Takeshi Kasama and Satoshi Sakamoto and Yasuaki Kabe and Takeshi Imai and Yuki Yamaguchi and Keisuke Miyazawa and Hiroshi Handa}, title = {Vitamin K2 Covalently Binds to Bak and Induces Bak-Mediated Apoptosis}, journal = {Molecular Pharmacology}, year = 2013, } @article{CTT100691781, author = {Masaaki Kawano and Masanori Matsui and Hiroshi Handa}, title = {SV40 virus-like particles as an effective delivery system and its application to a vaccine carrier}, journal = {Expert Review of Vaccines}, year = 2013, } @article{CTT100691784, author = {Yuki Yamaguchi and Hirotaka Shibata and Hiroshi Handa}, title = {Transcription elongation factors DSIF and NELF: Promoter-proximal pausing and beyond}, journal = {Biochimica et Biophysica Acta. Gene Regulatory Mechanisms}, year = 2013, } @article{CTT100691787, author = {Tadashi Wada and Masatoshi Hara and Takuya Taneda and Cao Qingfu and Ryouhei Takata and Kanako Moro and Kei Takeda and Takeo Kishimoto and Hiroshi Handa}, title = {Antisense morpholino targeting just upstream from a poly(A) tail junction of maternal mRNA removes the tail and inhibits translation}, journal = {Nucleic Acids Res.}, year = 2012, } @article{CTT100748892, author = {Yuki Ito and Takumi Ito and Satoki Karasawa and Teruya Enomoto and Nashimoto, Akihiro and Hase, Yasuyoshi and Sakamoto, Satoshi and Mimori, Tsuneyo and Yoshihisa Matsumoto and Yuki Yamaguchi and HIROSHI HANDA}, title = {Identification of DNA-Dependent Protein Kinase Catalytic Subunit (DNA-PKcs) as a Novel Target of Bisphenol A}, journal = {Plos One}, year = 2012, } @article{CTT100691788, author = {Lopez-Girona and Mendy D and Ito T and Miller K and Gandhi AK and Kang J and Karasawa S and Carmel G and Jackson P and Abbasian M and Mahmoudi A and Cathers B and Rychak E and Gaidarova S and Chen R and Schafer PH and Handa H and Daniel TO and Evans JF and Chopra R.}, title = {Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide}, journal = {Leukemia}, year = 2012, } @article{CTT100691786, author = {Gil Diamant and Liat Amir-Zilberstein and Yuki Yamaguchi and Hiroshi Handa and Rivka Dikstein}, title = {DSIF Restricts NF-κB Signaling by Coordinating Elongation with mRNA Processing of Negative Feedback Genes}, journal = {Cell Reports}, year = 2012, } @article{CTT100691791, author = {Satoshi Sakamoto and Mamoru Hatakeyama and Takumi Ito and Hiroshi Handa}, title = {Tools and methodologies capable of isolating and identifying a target molecule for a bioactive compound}, journal = {Bioorganic & Medicinal Chemistry}, year = 2012, } @article{CTT100691790, author = {Emiko Okuda-Ashitaka and Toshiaki Minami and Shingo Tsubouchi and Hiroshi Kiyonari and Akihiro Iwamatsu and Tetsuo Noda and Hiroshi Handa and Seiji Ito}, title = {Identification of NIPSNAP1 as a nocistatin-interacting protein involving pain transmission}, journal = {J Biol Chem}, year = 2012, } @article{CTT100691789, author = {HIROSHI HANDA and Takumi Ito}, title = {Deciphering the mystery of thalidomide teratogenicity}, journal = {Congenital Anomalies}, year = 2012, } @article{CTT100658974, author = {74. M. ABE and T. UEDA and T. MASAKI and Y. KITAMOTO and N. MATSUSHITA and H. HANDA}, title = {Detecting Ferrite Nanobeads for Sentinel Lymph Node Mapping with a Highly Sensitive Hall Differential Magnetic Field Sensor}, journal = {Journal of physics : conference series}, year = 2012, } @article{CTT100691793, author = {Teruya Enomoto and Iwao Kukimoto and Masa-aki Kawano and Yuki Yamaguchi and Arnold J. Berk and Hiroshi Handa}, title = {In vitro reconstitution of SV40 particles that are composed of VP1/2/3 capsid proteins and nucleosomal DNA and direct efficient gene transfer}, journal = {Virology}, year = 2011, } @article{CTT100691794, author = {Yuichi Kitai and Hajime Fukuda and Teruya Enomoto and Yuki Asakawa and Takahiro Suzuki and Satoshi Inouye and Hiroshi Handa}, title = {Cell selective targeting of a simian virus 40 virus-like particle conjugated to epidermal growth factor}, journal = {Journal of Biotechnology}, year = 2011, } @article{CTT100691795, author = {Ayako Yasuma and Toyoko Ochiai and Motoki Azuma and Hiroyuki Nishiyama and Ken Kikuchi and Masao Kondo and Hiroshi Handa}, title = {Exogenous coproporphyrin III production by Corynebacterium aurimucosum and Microbacterium oxydans in erythrasma lesions}, journal = {J. Med. Microbiol.}, year = 2011, } @article{CTT100691801, author = {Miho Aizawa and Yuichi Abe and Takumi Ito and Hiroshi Handa and Hiroyuki Nawa}, title = {mRNA distribution of the thalidomide binding protein cereblon in adult mouse brain}, journal = {Neuroscience Research}, year = 2011, } @article{CTT100691805, author = {Naoya Maekawa and Masaki Hiramoto and Satoshi Sakamoto and Motoki Azuma and Takumi Ito and Marie Ikeda and Michitaka Naitou and Hukum P. Acharya and Yuichi Kobayashi and Makoto Suematsu and Hiroshi Handa and Takeshi Imai}, title = {High-performance affinity purification for identification of 15-deoxy-Δ12,14-PGJ2 interacting factors using magnetic nanobeads}, journal = {Biomedical Chromatography}, year = 2011, } @article{CTT100691792, author = {Ayumi Kawano and Yohei Hayashi and Shuhei Noguchi and Hiroshi Handa and Masami Horikoshi and Yuki Yamaguchi}, title = {Global analysis for functional residues of histone variant Htz1 using the comprehensive point mutant library}, journal = {Genes Cells}, year = 2011, } @article{CTT100691799, author = {Takumi Ito and Hideki Ando and Hiroshi Handa}, title = {Teratogenic effects of thalidomide: molecular mechanisms}, journal = {Cellular and Molecular Life Sciences}, year = 2011, } @article{CTT100691797, author = {Mamoru Hatakeyama and Hiroshi Kishi and Yoshinori Kita and Kensuke Imai and Kosuke Nishio and Satoki Karasawa and Yuka Masaike and Satoshi Sakamoto and Adarsh Sandhu and Akihiro Tanimoto and Tatsuya Gomi and Eiichi Kohda and Masanori Abe and Hiroshi Handa}, title = {A two-step ligand exchange reaction generates highly water-dispersed magnetic nanoparticles for biomedical applications}, journal = {Journal of Materials Chemistry}, year = 2011, } @article{CTT100691803, author = {Takuya Taneda and Wenyan Zhu and Qingfu Cao and Hajime Watanabe and Yuki Yamaguchi and Hiroshi Handa and Tadashi Wada}, title = {Erythropoiesis is regulated by the transcription elongation factor Foggy/Spt5 through gata1 gene regulation}, journal = {Genes to Cells}, year = 2011, } @article{CTT100691807, author = {Adarsh Sandhu and Hiroshi Handa and Masanori Abe}, title = {Synthesis and applications of magnetic nanoparticles for biorecognition and point of care medical diagnostics}, journal = {Nanotechnology}, year = 2010, } @article{CTT100614755, author = {Kunitoshi Chiba and Junichi Yamamoto and Yuki Yamaguchi and Hiroshi Handa}, title = {Promoter-proximal pausing and its release: molecular mechanisms and physiological functions}, journal = {Exp. Cell Res.}, year = 2010, } @article{CTT100614756, author = {Sol Kim and Junichi Yamamoto and Yexi Chen and Masatoshi Aida and Tadashi Wada and Hiroshi Handa and Yuki Yamaguchi}, title = {Evidence that cleavage factor Im is a heterotetrameric protein complex controlling alternative polyadenylation}, journal = {Genes Cells}, year = 2010, } @article{CTT100691811, author = {Masaki Hiramoto and Naoya Maekawa and Takeshi Kuge and Fumiaki Ayabe and Atsushi Watanabe and Yuka Masaike and Mamoru Hatakeyama and Hiroshi Handa and Takeshi Imai}, title = {High-performance affinity chromatography method for identification of L-arginine interacting factors using magnetic nanobeads}, journal = {Biomedical Chromatography}, year = 2010, } @article{CTT100691815, author = {Aiko Tominaga and Hideki Sugawara and Toshitaka Futagawa and Kazuhiko Inoue and Kazuki Sasaki and Naoto Minamino and Mamoru Hatakeyama and Hiroshi Handa and Atsuro Miyata}, title = {Characterization of the testis-specific promoter region in the human pituitary adenylate cyclase-activating polypeptide (PACAP) gene}, journal = {Genes to Cells}, year = 2010, } @article{CTT100691808, author = {Sang Yoon Park and Pil Joo Ko and Hiroshi Handa and Adarsh Sandhu}, title = {Exploring magneto-optical properties of biofunctionalized magnetic chains for developing label-free immunoassays}, journal = {Journal of Applied Physics}, year = 2010, } @article{CTT100614754, author = {Kanako Kume and Yosuke Iizumi and Masashi Shimada and Yuki Ito and Tsutomu Kishi and Yuki Yamaguchi and Hiroshi Handa}, title = {Role of N-end rule ubiquitin ligases UBR1 and UBR2 in regulating the leucine-mTOR signaling pathway}, journal = {Genes Cells}, year = 2010, } @article{CTT100691806, author = {Yoshitaka Morimoto and Tsukasa Takamura and Sang Yoon Park and Satoshi Sakamoto and Shintaro Kawata and Hiroshi Handa and Adarsh Sandhu}, title = {Detection of 8 nm Diameter Superparamagnetic Beads by Magnetically-Induced Manipulation of Micrometer-Sized Magnetic Beads: A Novel Protocol for Magnetically-Labeled Biosensing}, journal = {Japanese Journal of Applied Physics}, year = 2010, } @article{CTT100614753, author = {Takumi Ito and Hideki Ando and Takayuki Suzuki and Toshihiko Ogura and Kentaro Hotta and Yoshimasa Imamura and Yuki Yamaguchi and Hiroshi Handa}, title = {Identification of a primary target of thalidomide teratogenicity}, journal = {Science}, year = 2010, } @article{CTT100691810, author = {Yuka Masaike and Takeshi Takagi and Masataka Hirota and Joe Yamada and Satoru Ishihara and Tetsu M. C. Yung and Takamasa Inoue and Chika Sawa and Hiroshi Sagara and Satoshi Sakamoto and Yasuyuki Takahashi and Yuki Yamaguchi and Hiroshi Handa and Yasuaki Kabe}, title = {Identification of Dynamin-2-Mediated Endocytosis as a New Target of Osteoporosis Drugs, Bisphosphonates}, journal = {Molecular Pharmacology}, year = 2010, } @article{CTT100691809, author = {Sang Yoon Park and Hiroshi Handa and Adarsh Sandhu}, title = {Magneto-Optical Biosensing Platform Based on Light Scattering from Self-Assembled Chains of Functionalized Rotating Magnetic Beads}, journal = {NANO LETT.}, year = 2010, } @article{CTT100597661, author = {Yexi Chen and Yuki Yamaguchi and Yuta Tsugeno and Junichi Yamamoto and Tomoko Yamada and Mitsuhiro Nakamura and Koji Hisatake and Hiroshi Handa}, title = {DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation}, journal = {Genes Dev.}, year = 2009, } @article{CTT100614750, author = {Hui Chen and Xavier Contreras and Yuki Yamaguchi and Hiroshi Handa and B. Matija Peterlin and Su Guo}, title = {Repression of RNA Polymerase II elongation in vivo is critically dependent on the C-terminus of Spt5}, journal = {PLoS ONE}, year = 2009, } @article{CTT100597657, author = {Tetsu M. C. Yung and Takashi Narita and Toshiharu Komori and Yuki Yamaguchi and Hiroshi Handa}, title = {Cellular dynamics of the negative transcription elongation factor NELF}, journal = {Exp. Cell Res.}, year = 2009, } @article{CTT100597658, author = {Hiroyuki Kamiya and Akihiro Suzuki and Yuki Yamaguchi and Hiroshi Handa and Hideyoshi Harashima}, title = {Incorporation of 8-hydroxyguanosine (8-oxo-7,8-dihydroguanosine) 5'-triphosphate by bacterial and human RNA polymerases}, journal = {Free Radic. Biol. Med.}, year = 2009, } @article{CTT100597655, author = {Chikanori Kuramori and Yasuyoshi Hase and Koichi Hoshikawa and Keiko Watanabe and Takeyuki Nishi and Takako Hishiki and Tomoyoshi Soga and Akihiro Nashimoto and Yasuaki Kabe and Yuki Yamaguchi and Hajime Watanabe and Kohsuke Kataoka and Makoto Suematsu and Hiroshi Handa}, title = {Mono-(2-ethylhexyl) phthalate targets glycogen debranching enzyme and affects glycogen metabolism in rat testis}, journal = {Toxicol. Sci.}, year = 2009, } @article{CTT100597654, author = {Toshiharu Komori and Naoto Inukai and Tomoko Yamada and Yuki Yamaguchi and Hiroshi Handa}, title = {Role of human transcription elongation factor DSIF in the suppression of senescence and apoptosis}, journal = {Genes Cells}, year = 2009, } @article{CTT100597653, author = {Chikanori Kuramori and Motoki Azuma and Kanako Kume and Yuki Kaneko and Atsushi Inoue and Yuki Yamaguchi and Yasuaki Kabe and Takamitsu Hosoya and Masahiro Kizaki and Makoto Suematsu and Hiroshi Handa}, title = {Capsaicin binds to prohibitin 2 and displaces it from the mitochondria to the nucleus}, journal = {Biochem. Biophys. Res. Commun.}, year = 2009, } @article{CTT100598399, author = {HIROSHI HANDA}, title = {Preparation of spherical and uniform-sized ferrite nanoparticles with diameters between 50-150 nm for biomedical applications.}, journal = {J.Magn. Magn. Mater}, year = 2009, } @article{CTT100597656, author = {Satoshi Sakamoto and Yasuaki Kabe and Mamoru Hatakeyama and Yuki Yamaguchi and Hiroshi Handa}, title = {Development and application of high-performance affinity beads: toward chemical biology and drug discovery}, journal = {Chem. Rec.}, year = 2009, } @article{CTT100597650, author = {Kozue Ando and Satoshi Hirao and Yasuaki Kabe and Yuji Ogura and Iwao Sato and Yuki Yamaguchi and Tadashi Wada and Hiroshi Handa}, title = {A new APE1/Ref-1-dependent pathway leading to reduction of NF-kappaB and AP-1, and activation of their DNA-binding activity}, journal = {Nucleic Acids Res.}, year = 2008, } @article{CTT100597652, author = {Motoki Azuma and Yasuaki Kabe and Chikanori Kuramori and Masao Kondo and Yuki Yamaguchi and Hiroshi Handa}, title = {Adenine nucleotide translocator transports haem precursors into mitochondria}, journal = {PLoS One}, year = 2008, } @article{CTT100597651, author = {Ryou-u Takahashi and Shin-nosuke Kanesashi and Takamasa Inoue and Teruya Enomoto and Masa-aki Kawano and Hiroko Tsukamoto and Fumitaka Takeshita and Takeshi Imai and Takahiro Ochiya and Kohsuke Kataoka and Yuki Yamaguchi and Hiroshi Handa}, title = {Presentation of functional foreign peptides on the surface of SV40 virus-like particles}, journal = {J. Biotechnol.}, year = 2008, } @article{CTT100597649, author = {Masafumi Suzuki and Shoichiro Furukawa and Chikanori Kuramori and Chika Sawa and Yasuaki Kabe and Mitsuhiro Nakamura and Jun-ichi Sawada and Yuki Yamaguchi and Satoshi Sakamoto and Satoshi Inouye and Hiroshi Handa}, title = {Development of a chemical screening system using aqueorin-fused protein}, journal = {Biochem. Biophys. Res. Commun.}, year = 2008, } @article{CTT100561850, author = {Matsushita Nobuhiro and Nakagawa Kazunori and Taniguchi Takaaki and Handa Hiroshi and Tada Masaru and Abe Masanori and Yoshimura Masahiro}, title = {Hundred-nanometer Sized Biomagnetic Beads with Large Magnetization Using Ferrite Nanoparticles Grown by Hydrothermal Process}, journal = {Journal of Applied Physics}, year = 2008, } @article{CTT100549875, author = {Takashi Narita and Yung, T.M.C. and Junichi Yamamoto and Tsuboi, Y. and Tanabe, H. and Tanaka, K. and Yamaguchi, Y. and HIROSHI HANDA and and }, title = {NELF interacts with CBC and participates in 3'-end processing of replication-dependent histone mRNAs}, journal = {Mol. Cell}, year = 2007, } @article{CTT100543743, author = {K. Nishio and M. Ikeda and N. Gokon and S. Tsubouchi and H. Narimatsu and Y. Mochizuki and S. Sakamoto and A. Sandhu and M. Abe and H. Handa}, title = {Preparation of size-controlled (30-100nm) magnetite nanoparticles for biomedical applications.}, journal = {J. Magn. Magn. Mater.}, year = 2007, } @article{CTT100543640, author = {Adarsh Sandhu and Yoshimich Kumagai and Adam Lapicki and Satoshi Sakamoto and Masanori Abe and Hiroshi Handa}, title = {High efficiency Hall effect micro-biosensor platform for detection of magnetically labeled biomolecules}, journal = {Biosensors & Bioelectronics}, year = 2007, } @article{CTT100561138, author = {Hitoshi Uga and Chikanori Kuramori and Akiko Ohta and Yasunori Tsuboi and Hiroshi Tanaka and Mamoru Hatakeyama and Yuki Yamaguchi and Masahiro Kizaki and Takashi Takahashi and Hiroshi Handa}, title = {A new mechanism of methotrexate action revealed by target screening with affinity beads}, journal = {Mol. Pharmacol.}, year = 2006, } @article{CTT100660695, author = {Hisakage Funabashi and Yasuhiro Tanaka and Yoshimasa Imamura and Masayasu Mie and Takashi Manabe and Hiroshi Tanaka and Takashi Takahashi and Hiroshi Handa and Masuo Aizawa and Eiry Kobatake}, title = {Glucose oxidase assisted homogeneous electrochemical receptor binding assay for drug screening}, journal = {Biosens Bioelectron}, year = 2006, } @article{CTT100528209, author = {Kusunoki, N. and Ito, T. and Sakurai, N. and Handa, H. and Kawai S.}, title = {A celecoxib derivative potently inhibits proliferation of colon adenocarcinoma cells by induction of apoptosis.}, journal = {Anticancer Res.}, year = 2006, } @article{CTT100528208, author = {Kubo, T. and Wada, T. and Yamaguchi, Y. and Shimizu, A. and Handa, H.}, title = {Knock-down of 25-kDa Subunit of Cleavage Factor Im in HeLa Cells Alters Alternative Polyadenylation within 3’UTRs.}, journal = {Nucleic Acids Res.}, year = 2006, } @article{CTT100533566, author = {Okawa, K. and Sekine, M. and Maeda, M. and Tada, M. and Abe, M. and Matsushita, N. and Nishio, K. and Handa, H.}, title = {Heating ability of magnetite nanobeads with various sizes for magnetic hyperthermia at120kHz, a noninvasive frequency.}, journal = {J. Appl. Phys.}, year = 2006, } @article{CTT100533567, author = {Maeda, M. and Kuroda, S. and Shimura, T. and Tada, M. and Abe, M. and Yamamuro, S. and Sumiyama, K. and Handa, H.}, title = {Magnetic carriers of iron nanoparticles coated with a functional polymer for high thoughput bio-screening.}, journal = {J. Appl. Phys.}, year = 2006, } @article{CTT100533569, author = {Togawa, K. and Sanbonsugi, H. and Sandhu, A. and Narimatsu, H. and Nishio, K. and Handa, H.}, title = {Detection of magnetically labeled DNA using pseudomorphic AlGaAs/InGaAs/GaAs heterostructure micro-Hall biosensor.}, journal = {J. Appl. Phys.}, year = 2006, } @article{CTT100529432, author = {Ogura, Y. and Azuma, M. and Tsuboi, Y. and Kabe, Y. and Yamaguchi, Y. and Wada, T. and Watanabe, H. and Handa, H.}, title = {TFII-I down-regulates a subset of estrogen-responsive genes through its interaction with an initiator element and estrogen receptor alpha.}, journal = {Genes Cells.}, year = 2006, } @article{CTT100529436, author = {Kawano, M. and Inoue, T. and Tsukamoto, H. and Takaya, T. and Enomoto, T. and Takahashi, R. U. and Yokoyama, N. and Yamamoto, N. and Nakanishi, A. and Imai, T. and Wada, T. and Kataoka, K. and Handa, H.}, title = {The VP2/VP3 minor capsid ptotein of SV40 promotes the in vitro assembly of the major capsid protein VP1 into particles.}, journal = {J. Biol. Chem.}, year = 2006, } @article{CTT100529441, author = {Sakurai, N. and Miki, Y. and Suzuki, T and Watanabe, K. and Narita, T. and Ando, K. and Young, T.C.Y. and Aoki, D. and Sasano, H. and Handa, H.}, title = {Systemic Distribution and Tissue Localizations of Human 17beta-Hydroxysteroid Dehydrogenase Type 12.}, journal = {J. Steroid Biochem. Mol. Biol.}, year = 2006, } @article{CTT100529455, author = {Aida, M. and Chen, Y. and Nakajima, K. and Yamaguchi, Y. and Wada, T. and Handa, H.}, title = {Transcriptional pausing caused by NELF plays a dual role in regulating immediate-early expression of the junB gene.}, journal = {Mol. Cell. Biol.}, year = 2006, } @article{CTT100529467, author = {Nishio, K. and Gokon, N. and Tsubouchi, S. and Ikeda, M. and Narimatsu, H. and Sakamoto, S. and Izumi, Y. and Abe, M. and Handa, H.}, title = {Direct Detection of Redox Reactions of Sulfur-containing Compounds on Ferrite Nanoparticle (FP) Surface.}, journal = {Chem. Lett.}, year = 2006, } @article{CTT100529479, author = {Kabe, Y. and Ohmori, M. and Shinouchi, K. and Tsuboi, Y. and Hirao, S. and Azuma, M. and Watanabe, H. and Okura, I. and Handa, H.}, title = {Porphrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier.}, journal = {J. Biol. Chem.}, year = 2006, } @article{CTT100529482, author = {Uga, H. and Kuramori, C. and Ohta, A. and Tsuboi, Y. and Tanaka, H. and Hatakeyama, M. and Yamaguchi, Y. and Takahashi, T. and Kizaki, M. and Handa, H.}, title = {A new mechanism of methotrxate action revealed by target screening with affinity beads.}, journal = {Mol. Pharmacol.}, year = 2006, } @article{CTT100533563, author = {Yamamoto, N. and Suzuki, M. and Kawano, M. and Inoue, T. and Takahashi, R. and Tsukamoto, H. and Enomoto, T. and Yamaguchi, Y. and Wada, T. and Handa, H.}, title = {Adeno-associated virus site-specific integration is regulated by TRP-185.}, journal = {J.Virol.}, year = 2006, } @article{CTT100533564, author = {Yugami, M. and Kabe, Y. and Yamaguchi, Y. and Wada, T. and Handa, H.}, title = {hnRNP-U enhances the expression of specific genes by stabilizing mRNA.}, journal = {FEBS Lett.}, year = 2006, } @article{CTT100533565, author = {Kumagai, Y. and Togawa, K. and Sakamoto, S. and Abe, M. and Handa, H. and Sandhu, A.}, title = {Hall biosensor with integrated current microstrips for control of magnetic beads.}, journal = {IEEE Trans. Magn. Soc.}, year = 2006, } @article{CTT100388510, author = {Gang Wang and Michael A Balamotis and Jennitte L Stevens and Yuki Yamaguchi and Hiroshi Handa and Arnold Berk}, title = {Mediator Requirement for Both Recruitment and Post-Recruitment Steps in Transcription Initiation.}, journal = {Mol.Cell}, year = 2005, } @article{CTT100390420, author = {Wu and C-H. and Lee, C. and Fan, R. and Smith, J.M. and Yamaguchi, Y. and Handa, H. and Gilmour, D.S.}, title = {Molecular characterization of Drosophila NELF.}, journal = {Nucleic Acids Res.}, year = 2005, } @article{CTT100408828, author = {Sandhu, A. and Handa. H.}, title = {Practical Hall Sensors for Biomedical Instrumentation}, journal = {IEEE Trans Magn}, year = 2005, } @article{CTT100408829, author = {Lapicki. A. and Sanbonsugi. H. and Yamamura. T. and Matsuhita. N. and Abe. M. and Narimatsu. H. and Handa. H. and Sandhu, A.}, title = {Functionalization of Micro-Hall Effect Sensors for Biomedical Applications Utilizing Superparamagnetic Beads}, journal = {IEEE Trans Magn.}, year = 2005, } @article{CTT100408830, author = {Togawa. K. and Sanbonsugi. H. and Lapicki. A. and Abe. M. and Handa. H. and Sandhu, A.}, title = {High Sensitivity InSb Thin Film Micro-Hall Sensor Arrays for Simultaneous Multiple Detection of Magnetic Beads for Biomedical Applications}, journal = {IEEE Trans Magn.}, year = 2005, } @article{CTT100408831, author = {Hasegawa, M. and Ohno, H. and Tanaka, H. and Hatakeyama, M. and Kawaguchi, H. and Takahashi, T. and Handa, H.}, title = {Affinity Identification of δ Opioid Receptors Using Latex Nanoparticles.}, journal = {Bioorg. Med. Chem. Lett.}, year = 2005, } @article{CTT100408832, author = {Azuma, N. and Tadokora, K. and Asaka, A. and Yamada, M. and Yamaguchi, Y. and Handa, H. and Matsushima, S. and Watanabe, T. and Kida, Y. and Ogura, T. and Shimamura, K. and Nakafuku, M.}, title = {Transdifferntiation of the retinal pigment epithelia to the neural retina by transfer of the Pax6 transcription factor.}, journal = {Hum. Mol. Genet.}, year = 2005, } @article{CTT100408833, author = {Urano, A. and Endoh, M. and Wada, T. and Morikawa, Y. and Itoh, M. and Kataoka, Y. and Taki, T. and Akazawa, H. and Nakajima, H. and Komuro, I. and Yoshida, N. and Hayashi, Y. and Handa, H. and Kitamura, T. and Nosaka, T.}, title = {Infertility with defective spermiogenesis in mice lacking AF5q31, the target of  chromosomal translocation in human infant leukemia.}, journal = {Mol. Cell. Biol.}, year = 2005, } @article{CTT100408834, author = {Kusunoki, N. and Ito, T. and Sakurai, N. and Suguro, T. and Handa, H. and Kawai, S.}, title = {A novel celecoxib derivative potently induces apoptosis of human synovial fibroblasts.}, journal = {J Pharmcol. Exp. Ther.}, year = 2005, } @article{CTT100408836, author = {Delehouzee, S. and Yoshikawa, T. and Sawa, C. and Sawada and J-I. and Ito, T. and Omori, M. and Wada, T and Yamaguchi, Y. and Kabe, Y. and Handa, H.}, title = {GABP, HCF-1 and YY1 are involved in Rb gene expression during myogenesis.}, journal = {Genes Cells}, year = 2005, } @article{CTT100408837, author = {Shimizu, N. and Ouchida, R. and Yoshikawa, N. and Hisada, T. and Watanabe, H. and Okamoto, K. and Kusuhara, M. and Handa, H. and Morimoto, C and Tanaka, H.}, title = {HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b.}, journal = {Proc. Natl. Acad. Sci. USA}, year = 2005, } @article{CTT100408838, author = {Oba, S. and Hatakeyama, M. and Handa, H and Kawaguchi, H.}, title = {Development of polymer latex particles for selctive cleavage of mismatched DNA and their application for DNA diagnosis.}, journal = {Bioconjugate Chemistry}, year = 2005, } @article{CTT100408839, author = {Tsubouchi, S. and Nishio, K. and Ikeda, M. and Narimatsu, H. and Gokon, N. and Handa, H. and Abe, M.}, title = {Polymer coating of ferrite nanoparticles by using “connecter” chemical compounds.}, journal = {Proceedings of the Ninth International Conference on Ferrites (ICF-9)}, year = 2005, } @article{CTT100408840, author = {Wu and C-H. and Lee, C. and Fan, R. and Smith, J.M. and Yamaguchi, Y. and Handa, H. and Gilmour, D.S.}, title = {Molecular characterization of Drosophila NELF.}, journal = {Nucleic Acids Res.}, year = 2005, } @article{CTT100408841, author = {Wang, G. and Balamotis, M.A. and Stevens, J.L. and Yamaguchi, Y. and Handa, H. and Berk, A.}, title = {Mediator requirement for both and post-requirement steps in transcription initiation.}, journal = {Mol. Cell.}, year = 2005, } @article{CTT100408842, author = {Young, T.C.Y. and Rancourt, A. and Ho, E.L.Y. and Parent, M. and Vispe, S. and Suzuki-Matsuda, F. and Uehara, A. and Wada, T. and Handa, H. and Sato, M.}, title = {Poly(ADP-ribose)polymerase-1 is a negative regulator of HIV-1 expression through competitive binding to TAR RNA.}, journal = {J. Biol. Chem.}, year = 2005, } @article{CTT100408843, author = {Ohtsu, Y. and Ohba, R. and Imamura, Y. and Kobayashi, M. and Hatori, H. and Zenkoh, T. and Hatakeyama, M. and Manabe, T. and Hino, M. and Yamaguchi, Y. and Kataoka, K. and Kawaguchi, H. and Watanabe, H. and Handa, H.}, title = {Selective ligand purification using high-performance affinity beads.}, journal = {Anal. Biochem.}, year = 2005, } @article{CTT100408844, author = {Kabe, Y. and Yamada, J. and Uga, H. and Yamaguchi, Y. and Wada, T. and Handa, H.}, title = {NF-Y is essential for the recruitment of RNA polymerase II and synergistically acts the induced transcription on CCAAT box containing promoters.}, journal = {Mol. Cell. Biol.}, year = 2005, } @article{CTT100408845, author = {Kabe, Y. and Hirao, S. and Ando, K. and Handa, H.}, title = {Redox Regulation of NF-kappa B activation-the distinct redox regulation between the cytoplasm and the nucleus.}, journal = {Antioxid. Redox. Signal.}, year = 2005, } @article{CTT100561510, author = {Hidetaka Hatori and Tatsuya Zenkoh and Motoo Kobayashi and Yoshihiro Ohtsu and Hiroshi Tanaka and Nobuharu Shigematsu and Hiroyuki Setoi and Motohiro Hino and Haruma Kawaguchi and Takashi Takahashi and Hiroshi Handa}, title = {FR225659-binding Proteins: Identification as Serine/Threonine Protein Phosphatase PP1 and PP2A Using High-performance Affinity Beads}, journal = {J. Antibiotics}, year = 2004, } @article{CTT100561509, author = {Tatsuya Zenkoh and Hidetaka Hatori and Hiroshi Tanaka and Makoto Hasegawa and Mamoru Hatakeyama and Yasuaki Kabe and Hiroyuki Setoi and Haruma Kawaguchi and Hiroshi Handa and Takashi Takashi}, title = {Design and Synthesis of a Solid-Supported FR225659 Derivative for Its Receptor Screening}, journal = {Organic Letters}, year = 2004, } @article{CTT100388507, author = {S.Mandal and C.Chu and T.Wada and H.Handa and A.J.Shatkin and D.Reinberg}, title = {Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate transcription during promoter escape.}, journal = {Proc. Natl. Acad. Sci. USA.}, year = 2004, } @article{CTT100489128, author = {宇賀均 and 加部泰明 and 大羽玲子 and 明石哲行 and 長谷川慎 and 半田宏}, title = {新しいアフェニティビーズによる薬剤標的タンパク質の精製}, journal = {秀潤社}, year = 2003, } @article{CTT100489131, author = {山田丈 and 櫻井信行 and 半田宏}, title = {創薬標的分子のスクリーニング}, journal = {現代医療社}, year = 2003, } @article{CTT100489206, author = {HIROSHI HANDA}, title = {New approach to chemical biology for drug development:construction of new affinity beads and their application.}, journal = {Arthritis Research & Therapy.3rd World Congress of the Global Arthiris Research Network(GRAN):Internal Arthritis summit,5,S27.}, year = 2003, } @article{CTT100476433, author = {Y.Yamaguchi and S.Delehouzee and H.Handa}, title = {HIV and HDV: evolution takes different paths to relieve blocks in transcriptional elongation.}, journal = {Microbes and Infection}, year = 2002, } @article{CTT100466423, author = {T.Tomohiro and J.Sawada and C.Sawa and H.Nakura and S.Yoshida and M.Kadaka and M.Hatakeyama and H.Kawaguchi and H.Handa and H.Okuno.}, title = {Total analysis and purification of cellular proteins brinding to cisplatin-damaged DNA using submicron beads.}, journal = {Bioconjug.Chem.}, year = 2002, } @article{CTT100480789, author = {和田忠士 and 山口雄輝 and 半田宏}, title = {mRNA合成速度の分子スイッチ}, journal = {蛋白質核酸酵素}, year = 2002, } @article{CTT100476436, author = {K.Kataoka and S-I.Han and S.Shioda and M.Hirai and M.Nishizawa and H.Handa.}, title = {MafA is glucose-regulated and pancreatic b-cell-specific transcriptional activator for the insulin gene.}, journal = {J. Biol. Chem.}, year = 2002, } @article{CTT100476435, author = {T.Nishi and N.Shimizu and M.Hiramoto and I.Sato and Y.Yamaguchi and M.Hasegawa and S.Aizawa and H.Tanaka and K.Kataoka and H.Watanabe and H.Handa}, title = {Spatial redox regulation of a critical cysteine residue of NF-kB in vivo}, journal = {J.Biol. Chem.}, year = 2002, } @article{CTT100476434, author = {T.Oda and A.Ueda and N.Shimizu and H.Handa and T.Kasahara}, title = {Suppression of monocyte chemoattractant protein 1, but not IL-8, by alprazolam: Effect of alprazolam on c-Rel/p65 and c-Rel/p50 binding to the monocyte chemoattractant protein 1 promoter region.}, journal = {J.Immunol}, year = 2002, } @article{CTT100466421, author = {M.Hiramoto and N.Shimizu and T.Nishi and D.Shima and S.Aizawa and H.Tanaka and M.Hatakeyama and H.Kawaguchi and H.Handa}, title = {High-performance affinity beads for identifying anti-NF-κB drug receptors.}, journal = {Methods Enzymol.}, year = 2002, } @article{CTT100466422, author = { K.Nishimura and M.Hasegawa and Y.Ogura and T.Nishi and K.Kataoka and H.Handa and M.Abe.}, title = {4℃ preparation of ferrite nanoparticles having protein molecules immobilized on their surfaces.}, journal = {J. Appl. Phys.}, year = 2002, } @article{CTT100466424, author = { C.Sawa and T.Yoshikawa and F.Matsuda-Suzuki and S.Delehouzee and M.Goto and H.Watanabe and J.Sawada and K.Kataoka and H.Handa.}, title = {YEAF1/RYBP and YAF-2 Are Functionally Distinct Members of a Confactor Family for the YY1 and E4TF1/hGABP Transcription Factors.}, journal = {J.Biol. Chem.}, year = 2002, } @article{CTT100466861, author = {Y.Yamaguchi and N.Inukai and T.Narita and T.Wada and H.Handa}, title = { Evidence that NFLF represses transcription elongation through binding to a DSIF/RNA polymerase II complex and RNA.}, journal = {Mol.Cell.Biol.}, year = 2002, } @article{CTT100476432, author = {H.Watanabe and A.Suzuki and T.Mizutani and S.Kohno and D.S.Lubahn and H.Handa and T.Iguchi.}, title = {Genome-wide analysis of changes in early gene expression induced by oestrogen.}, journal = {Genes Cells}, year = 2002, } @article{CTT100454464, author = {嶋大輔 and 松本明子 and Sophie Delehouzee and 山田丈 and 湯上真人 and 半田宏}, title = {新規アフィニティビーズの創薬への応用}, journal = {バイオベンチャー}, year = 2001, } @article{CTT100453962, author = {T.Yoshimatsu and A.Saitoh and J.Ryu and D.Shima and H.Handa and M.Hiramoto and Y.Kawakami and S.Aizawa}, title = {Characterization of immortalized human chondrocytes originated from osteoarthritis cartilage}, journal = {Int. J. Mol. Med.}, year = 2001, } @article{CTT100454466, author = {長谷川慎 and 清水宣明 and 宇賀均 and 半田宏}, title = {アフィニティビーズによる薬剤生体レセプターの探索と創薬への応用}, journal = {バイオサイエンスとインダストリー}, year = 2001, } @article{CTT100454548, author = {S.B.Lavoie and A.L.Albert and H.Handa and M.Vincent and O.Bensaude}, title = {The peptidyl-prolyl isomerase Pin1 interacts with hSpt5 phosphorylated by Cdk9}, journal = {J.Mol.Biol.}, year = 2001, } @article{CTT100452255, author = {西剛志 and 長谷川慎 and 半田宏}, title = {生体レセプターを基盤とした創薬}, journal = {ファルマシア}, year = 2001, } @article{CTT100452254, author = {山口雄輝 and 半田宏}, title = {正反対の機能を使い分ける新たな転写調節因子、}, journal = {化学と生物}, year = 2001, } @article{CTT100452228, author = {K.Shiba and T.Hamaguchi and K.Kataoka and Y.Yamaguchi and H.Handa and K.Adachi}, title = {Cloning of the hamster androgen receptor gene.}, journal = {J. Dermatol. Sci.}, year = 2001, } @article{CTT100452227, author = {Y.Yamaguchi and T.Narita and N.Inukai and T.Wada and H.Handa}, title = {SPT Genes: Key players in the regulation of transcription, chromatin structure and other cellular processes. (review)}, journal = {J. Biochem.}, year = 2001, } @article{CTT100452226, author = {E.Morii and H.Ogihara and K.Oboki and C.Sawa and T.Sakuma and S.Nomura and J.D.Esko and H.Handa and Y.Kitamura.}, title = {Inhibitory effect of MITF encoded by the mutant mi allele on GABP-mediated transcript expression in mouse mast cells.}, journal = {Blood}, year = 2001, } @article{CTT100452225, author = {Y.Yamaguchi and J.Filipovska and K.Yano and A.Furuya and N.Inukai and T.Narita and T.Wada and S.Sugimoto and M.M.Konarska and H.Handa.}, title = {Stimulation of RNA polymerase II elongation by Hepatitis delta antigen.}, journal = {Science}, year = 2001, } @article{CTT100451724, author = {D-K.Kim and Y.Yamaguchi and T.Wada and H.Handa}, title = {The regulation of elongation by eukaryotic RNA polymerase II: A recent view. (review)}, journal = {Mol. Cells}, year = 2001, } @article{CTT100451723, author = {M.Sakai and N.Matsumoto and Y.Kitamoto and H.Kawaguchi and H.Handa and M.Abe.}, title = {Ferrite plating of styrene-glycidyl methacrylate latex particles for bioseparator and DNA diagnosis. Ferrites:}, journal = {Proceedings of the Eighth International Conference on Ferrites (ICF 8), Kyoto and Tokyo}, year = 2001, } @article{CTT100451722, author = {K.Kataoka and H.Handa and M.Nishizawa.}, title = {Induction of cellular anti-oxidative stress genes through heterodimeric transcription factor Nrf2/smallMafby anti-rheumatic gold (I) compounds.}, journal = {J. Biol. Chem.}, year = 2001, } @article{CTT100451721, author = {K.Kataoka and S.Shioda and K.Yoshitomo-Nakagawa and H.Handa and M.Nishizawa.}, title = {Maf and Jun nuclear oncoproteins share down stream target genes for inducing cell transformation in press.}, journal = {J.Biol. Chem.}, year = 2001, } @article{CTT100438333, author = {K-I.Ishizu and H.Watanabe and S-I.Han and S-N.Kanesashi and M.Hoque and H.Yajima and K.Kataoka and H.Handa}, title = {The roles of disulfide linkage and calcium ion-mediated interactions in assembly and disassembly by viruslike particles composed of SV40 VP1 capsid protein}, journal = {J.Virol.}, year = 2001, } @article{CTT100438332, author = {S.Guo and Y.Yamaguchi and S.Schilbach and T.Wada and J.Lee and A.Goddard and D.French and H.Handa and A.Rosenthal}, title = {A regulator of transcriptional elongation controls vertebrate neuronal development}, journal = {Nature}, year = 2001, } @article{CTT100438337, author = {M.Takayama and E.Kim and M.Kidokoro and K.Shimamura and K.Shiroki and H.Yajima and S.Ito and H.Handa and S.Inokuchi}, title = {Transfer of SV40 temperature-sensitive early gene into human epidermal keratinocytes by the recombinant adenovirus vector}, journal = {In Vitro Cell. Dev. Biol.}, year = 2000, } @article{CTT100438336, author = {K.Araki-Sasaki and S.Aizawa and M.Hiramoto and M.Nakamura and O.Iwase and K.Nakata and Y.Sasaki and T.Mano and H.Handa and Y.Tano}, title = {substance P-induced cadherin expression and its signal transduction in a cloned human corneal epithelial cell line}, journal = {J.Cell.Physiol.}, year = 2000, } @article{CTT100438335, author = {N.Shimizu and K.Sugimoto and J.Tang and M.Hiramoto and S.Aizawa and A.Oomori and H.Watanabe and H.Tanaka and H.Kawaguchi and H.Handa}, title = {High performance affinity beads for identification of drug receptors}, journal = {Nature Biotechnol.}, year = 2000, } @article{CTT100438334, author = {T.Wada and G.Orphanides and J.Hasegawa and Dd-K.Kim and D.Shima and Y.Yamaguchi and A.Fukuda and K.Hisatake and S.Oh and D.Reinberg and H.Handa}, title = {FACT relieves DSIF/NELF-mediated inhibition of transcription elongation and reveals functional differences between P-TEFb and TFIIH}, journal = {Mol. Cell}, year = 2000, } @article{CTT100438273, author = {半田宏}, title = {affinity beadsの構築とその応用}, journal = {遺伝子医学}, year = 2000, } @article{CTT100452229, author = {H.Handa}, title = {Studies of the network of regulatory circuits formed by a family of transcription factors.}, journal = {The Waksman Foundation of Japan Inc. Research Report.}, year = 2000, } @article{CTT100465048, author = {半田宏 共訳 and 村松正實 監訳}, title = {ゲノム}, journal = {メディカル・サイエンス・インタ-ナショナル}, year = 2000, } @article{CTT100465049, author = {半田宏}, title = {affinity beadsの構築とその応用}, journal = {遺伝子医学}, year = 2000, } @article{CTT100438331, author = {S.Aizawa and N.Shimizu and H.Handa and M.Hiramoto and H.Hoshi and M.Nagasu and H.Kanno and Y.Nagasu and Y.Imanishi}, title = {Effects of cyclic polylactate(CPL) on the growth of cloned leukemic cells in vitro}, journal = {Hematol.Oncol.}, year = 2000, } @article{CTT100438310, author = {半田宏 and 西剛志 and 佐藤巌 and 清水宣明}, title = {転写因子をターゲットにした創薬}, journal = {BIO Clinica}, year = 2000, } @article{CTT100438303, author = {山口雄輝 and 和田忠士 and 半田宏}, title = {転写伸長反応の制御メカニズム}, journal = {実験医学}, year = 2000, } @article{CTT100438338, author = {S.Aizawa and M.Hiramoto and H.Hoshi and K.Toyama and D.Shima and H.Handa}, title = {Establishment of stromal cell line from an MDS RA patient which induced an apoptopic change in hematopoietic and leukemic cells in vitro}, journal = {Exp.Hematol.}, year = 2000, } @article{CTT100430124, author = {S.Aizawa and M.Nakano and O.Iwase and M.Yaguchi and M.Hiramoto and H.Hoshi and R.Nabeshima and D.Shima and H.Handa and K.Toyama}, title = {Bone marrow stroma from refractoty anemia of myelodysplastic syndrome is defective in its ability to support normal CD34- positive cell proliferation and differentiation in vitro.}, journal = {Leuk. Res.}, year = 1999, } @article{CTT100411731, author = {Y.Yamaguchi and T.Takagi and T.Wada and K.Yano and A.Furuya and S.Sugimoto and J.Hasegawa and H.handa}, title = {NELF, a multsubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation.}, journal = {Cell}, year = 1999, } @article{CTT100430134, author = {Y.Yamaguchi and T.Wada and D.Watanabe and T.Takagi and J.Hasegawa and H.Handa}, title = {Structure and function of the human transcription elongation factor DSIF}, journal = {J. Biol. Chem.}, year = 1999, } @article{CTT100430135, author = {F.Sanda and J.Kamatani and H.Handa and T.Endo}, title = {Radical polymerization behavior of a proline-substituted acrylamide. Effect of s-cis-s-trans isomerization on the polymerization}, journal = {Macromolecules}, year = 1999, } @article{CTT100430138, author = {S.Satoh and M.Hijikata and H.Handa and S.Shimotono}, title = {Caspase-mediated cleavage of eukaryotic translation initiation factor subunit 2 alpha.}, journal = {Biochem. J.}, year = 1999, } @article{CTT100430139, author = {M.Hashimoto and K.Chayama and M.Kobayashi and A.Tsubota and Y.Arase and S.Saitou and Y.Suzuki and K.Ikeda and M.Kobayashi and H.Handa and H.Kumada}, title = {Fluctuations of hepatitis C virus load are not related to amino acid substitutions in hyper variable region 1 and interferon sensitivity determining region}, journal = {J. Med. Virol.}, year = 1999, } @article{CTT100430140, author = {N.Azuma and Y.Yamguchi and H.Handa and M.Hayakawa and A.Kanai and M.Yamada}, title = {Missense mutation in the alternative splice region of the PAX6 gene in eye anomalies.}, journal = {Am. J. Hum. Genet.}, year = 1999, } @article{CTT100430141, author = {J.Ozaki and T.Ikegami and M.Mishima and T-I.Takemaru and K.Kabe and H.Handa and H.Ueda and S.Hirose and M.Shirakawa}, title = {Identification of the core domain and the secondary structure of the transcriptional coactivator MBE1.}, journal = {Genes Cells}, year = 1999, } @article{CTT100430142, author = {M.Hoque and K.Ishizu and A.Matsumoto and S-I.Han and F.Arisaka and M.Takayama and K.Suzuki and T.Kanda and K.Kato and H.Watanabe and H.Handa}, title = {Nuclear transport of the major capsid protein is essential for the capsid formation of adeno-associated virus.}, journal = {J. Virol.}, year = 1999, } @article{CTT100431655, author = {J.A.Kim and Y.Yamaguchi and T.Wada and H.Handa and P.A.Sharp}, title = {Tat-SF1 protein associates with RAP30 of TFIIF and hSPT5 protein.}, journal = {Mol. Cell. Biol.}, year = 1999, } @article{CTT100431663, author = {H.Tsutsui and C.Geltinger and T.murata and K.itakura and T. Wada and H.Handa and K.K.Yokoyama}, title = {Tha DNA-binding and transcriptional activities of MAZ, a Myc-associated zinc finger protein, are regulated by casein kinase II.}, journal = {Biochem. Biophysic. Res. Commun.}, year = 1999, } @article{CTT100431664, author = {J-I.Sawada and F.Suzuki and C.Sawa and M.Goto and H.Watanabe and H.Handa}, title = {Synergistic transcriptional activation of hGABP and select members of the ATF/CREB family.}, journal = {J. Biol. Chem.}, year = 1999, } @article{CTT100431684, author = {M.Takayama and E.Kim and M.Kidokoro and K.Shimamura and K.Shiroki and H.Yajima and S.Ito and H.Handa and S.Inokuchi}, title = {Transfer of SV40 temperature-sensitive early gege into human epidermal keratinicytes by the recombinant adenovirus vector.}, journal = {In Vitro Cell. Dev. Biol.}, year = 1999, } @article{CTT100431685, author = {M.Mishima and J.Ozaki and T.Ikegami and Y.Kabe and M.Goto and M.Ueda and S.Hirose and H.Handa and M.Shirakawa}, title = {Resonance assignments, secondary structure and 15N relaxation data of the human transcriptional coactivator hMBF1(57-148).}, journal = {J. Biomol. NMR}, year = 1999, } @article{CTT100431686, author = {Y.Kabe and M.Goto and D.Shima and T.Imai and T.Wada and K-I.Morohashi and S.Hirose and H.Handa}, title = {The role of human MBF1 as a transcriptional coactivator.}, journal = {J. Biol. Chem.}, year = 1999, } @article{CTT100431687, author = {K.Araki-Sasaki and S.Aizawa and M.Hiramoto and M.Nakamura and O.Iwase and K.Nakata and Y.Sasaki and T.Mano and H.Handa and Y.Tano}, title = {Substance P-induced cadherin expression and its signal transduction in a cloned human corneal epithelial cell line.}, journal = {J. Cell. Physiol.}, year = 1999, } @article{CTT100431688, author = {M.Hoque and N.Shimizu and K-I.Ishizu and H.Yajima and F.Arisaka and K.Suzuki and H.Watanabe and H.Handa}, title = {Chimeric virus-like particle formation of adeno-associated virus.}, journal = {Biochem. biophys. Res. Commun.}, year = 1999, } @article{CTT100431691, author = {半田宏 and 渡辺肇 and 清水宣明}, title = {創薬標的としての転写因子}, journal = {バイオサイエンスとインダストリ-}, year = 1999, } @article{CTT100431692, author = {半田宏 and 清水宣明}, title = {転写制御による疾患への介入をめざして}, journal = {医学のあゆみ}, year = 1999, } @article{CTT100465047, author = {半田宏 and 清水宣明}, title = {創薬標的としての転写因子}, journal = {現代医療}, year = 1999, } @article{CTT100428975, author = {Y.Yamaguchi and T.Wada and F.suzuki and T.Takagi and J.Hasegawa and H.Handa}, title = {Casein kinase II interacts with the bZip domains of several transcription factors.}, journal = {Nucleic Acids Res.}, year = 1998, } @article{CTT100428977, author = {T.Wada and T.Takagi and Y.Yamaguchi and D.Watanabe and H.Handa}, title = {Evidence that p-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro.}, journal = {EMBO J.}, year = 1998, } @article{CTT100428978, author = {M.Toyoda and M.Goto and H.Handa and M.Shibuya}, title = {Involvement of MAP kinase-independent protein kinase C signaling pathway in the EGF-induced p21(WAF1/Cip1) expression and growth inhibition of A431 cells.}, journal = {Biochem.Biophys.Res.Commun.}, year = 1998, } @article{CTT100428976, author = {F.Suzuki and M.Goto and C.Sawa and S.Ito and H.Watanabe and J-I.Sawada and H.Handa}, title = {Functional interactions of transcription factor hGABP subunits}, journal = {J.Biol.Chem.}, year = 1998, } @article{CTT100430125, author = {H.Handa}, title = {Evidence that p.TEfb alleviates the negative effect of DSIF on RNA polymanase tramscription in vitro.}, journal = {EMBO J. [17] 7395-7403, 1998.}, year = 1998, } @article{CTT100428972, author = {I.Vassias and U.Hazan and Y.Michel and C.Sawa and H.Handa and L.Gouya and F.Morinet}, title = {Regulation of human B19 parvovirus promoter expression by hGABP (E4TF1) transcription factor.}, journal = {J.Biol.Chem.}, year = 1998, } @article{CTT100428971, author = {Y.Yamaguchi and T.Wada and H.Handa}, title = {Drawing a new view of DRB: Interplay between positive and negative elongation factors. (review)}, journal = {Genes Cells}, year = 1998, } @article{CTT100428967, author = {M.Hiramoto and S.Aizawa and O.Iwase and M.Nakano and K.Toyama and M.Hoque and R.Nabeshima and A.Kaidow and T.Imai and H.Hoshi and H.Handa}, title = {Stimulatory effects of substance P on CD34 positive cell proliferation and differentiation in vitro are mediated by the modulation of stromal cell function.}, journal = {Int.J.Mol.Med.}, year = 1998, } @article{CTT100465001, author = {T.B.van Dijk and B.Baltus and E.Caldenhoven and H.Handa and J.A.m.Raaijmakers and J-W.J.Lammers and L.Koenderman and R.P.de Groot }, title = {Cloning and characterization of the human interleukin-3 (IL-3)/IL-5/granulocyte-macrophage colony-stimulating factor receptor βc gene: Regulation by Ets family members }, journal = {Blood}, year = 1998, } @article{CTT100428966, author = {M.hiramoto and N.Shimizu and K.Sugimoto and J.Tang and K.Kawakami and M.Ito and S.Aizawa and H.Tanaka and I.Makino and H.Handa}, title = {Nuclear targetted suppression of NF-kB activity by the novel quinone derivative E3330.}, journal = {J.Immunol.}, year = 1998, } @article{CTT100428968, author = {T.Wada and T.Takagi and Y.Yamaguchi and A.Ferdous and T.Imai and S.Hirose and S.Sugimoto and K.Yano and G.A.Hartog and F.winston and S.Buratowski and h.Handa}, title = {DSIF, a novel negative transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs.}, journal = {Genes Dev.}, year = 1998, } @article{CTT100428970, author = {F.Hirano and H.Tanaka and Y.Hirano and M.hiramoto and H.Handa and I.Makino and C.Scheidereit}, title = {Functional interference of Sp1 and NF-kB through the same DNA binding site.}, journal = {Mol.Cell.Biol.}, year = 1998, } @article{CTT100428969, author = {G.A.Hartog and T.Wada and H.Handa and F.winston}, title = {Evidence that Spt4, Spt5, and spt6 control transcription by RNA polymerase II in Saccharomyces cerevisiae.}, journal = {Genes Dev.}, year = 1998, } @article{CTT100428973, author = {M.Hatakeyama and S.Iwato and K.Fujimoto and H.Handa and H.Kawaguchi}, title = {DNA-carrying latex particles for DNA diagnosis. 1. Separation of normal and point mutant DNAs according to the difference in hybridization efficiency}, journal = {Colloids and Surfaces B: Biointerfaces}, year = 1998, } @article{CTT100428974, author = {M.Hatakeyama and K.Nakamura and S.Iwato and H.Handa and K.fujimoto and H.Kawaguchi}, title = {DNA-carrying latex particles for DNA diagnosis. 2. Distinction of normal and point mutant DNA using S1 nuclease.}, journal = {Colloid and Surfaces B: Biointerfaces}, year = 1998, } @article{CTT100411776, author = {HIROSHI HANDA}, title = {NAP-1 is a functional homologo of TAF-1 thet is required for replication and transcription of the adanovirus gonome in chromatin-like structure.}, journal = {Genes to Cells}, year = 1997, } @article{CTT100411792, author = {HIROSHI HANDA}, title = {Retinoblastoma binding factor I site in the core promoter region of the human RB gene is activated by hGABP/E4TF1.}, journal = {Cancer Res.}, year = 1997, } @article{CTT100411791, author = {HIROSHI HANDA}, title = {Autoregnlation of pax6 transcriptianl activation by two distinct DNA-binding subdomains of the paired domain.}, journal = {Genes Cells}, year = 1997, } @article{CTT100411790, author = {HIROSHI HANDA}, title = {Molecular cloning of MBF2 reveals its contact with TFEA that leads to transcriptional activation.}, journal = {Genes Cells}, year = 1997, } @article{CTT100411785, author = {HIROSHI HANDA}, title = {Characterization of the human thrombopoietin gene promoter.}, journal = {J. Biol. Chem.}, year = 1997, } @article{CTT100411784, author = {HIROSHI HANDA}, title = {Inhibition of HIV-I protease by oxim devivatives.}, journal = {Biochem. Biophys. Res. Commun.}, year = 1997, } @article{CTT100411786, author = {HIROSHI HANDA}, title = {ERC-55, a binding protein for the papilloma virus E6 oncoprotein, specifically interacts with vitamin D receptor amony nuclear receptors}, journal = {Biochem. Biophys. Res. Commun.}, year = 1997, } @article{CTT100465000, author = {T.Komai and Y.Ishikawa and R.Yagi and H.Suzuki-Sugawara and T.Nishigaki and H.Handa}, title = {Possible involvement of bone marrow stromal cells in agranulocytosis caused by vesnarinone treatment }, journal = {Acta Hematologica}, year = 1997, } @article{CTT100464999, author = {T.Komai and Y.Ishikawa and R.Yagi and H.Suzuki-Sugawara and T.Nishigaki and H.Handa}, title = {Development of HIV-1 protease expression methods using T7 phage promoter system }, journal = {Appl. Microbiol. Biotechnol}, year = 1997, } @article{CTT100464998, author = {F.Momose and H.Handa and K.Nagata}, title = {Identification of host factors that regulate the influenza virus RNA polymerase activity }, journal = {Biochimie}, year = 1997, } @article{CTT100411789, author = {HIROSHI HANDA}, title = {The promoter of the androgen dependent gene in the flank argan of Ramsters.}, journal = {J. Dermatol. Sci}, year = 1997, } @article{CTT100411788, author = {HIROSHI HANDA}, title = {Effects of vesnarinone on the bone marrow stromal cell-dependent proliferation and differentiation of HL60 cells in vitro.}, journal = {Exp. Hematol.}, year = 1997, } @article{CTT100411787, author = {HIROSHI HANDA}, title = {Phosphorylation and high level oxpression of Fra-2 in v-src transformed cells : a pathway of activation of endogeneous AP-1.}, journal = {Oncogene}, year = 1997, } @article{CTT100465046, author = {半田宏 共著 and 田村隆明 and 村松正美編 }, title = {転写のメカニズムと疾患}, journal = {羊土社}, year = 1997, } @article{CTT100465045, author = {半田宏}, title = {「タンパク質化学 第3巻」(遺伝情報の発現)}, journal = {廣川書店}, year = 1997, } @article{CTT100465044, author = {山口雄輝 and 半田宏}, title = {転写因子とウイルス「転写因子とその異常」}, journal = {中外医学社}, year = 1997, } @article{CTT100411797, author = {半田宏}, title = {分子細胞生物学辞典}, journal = {東京化学同人}, year = 1997, } @article{CTT100411795, author = {HIROSHI HANDA}, title = {Promoter structure of the MxA gene that confers resistance to influenza virus.}, journal = {FEBS Lett.}, year = 1997, } @article{CTT100411793, author = {HIROSHI HANDA}, title = {Preparation of dimerized polypeptido-carrying microspheres and purification of specific proteins bound to these microspheres}, journal = {Colloids and Sunfaces B : Biointerfaces}, year = 1997, } @article{CTT100411775, author = {HIROSHI HANDA}, title = {Inhibition of H1V-1 protease by oxim devivatives}, journal = {Biochem. Bioplys. Res. Commun.}, year = 1997, } @article{CTT100411765, author = {HIROSHI HANDA}, title = {Mechanism for inhibition of influenza virus RNA polymeraso activity by matrix protein.}, journal = {J. Virol.}, year = 1996, } @article{CTT100411766, author = {HIROSHI HANDA}, title = {Assignment of the E4TF1-60 gene, an Ets-related transcription factor, to human chromosome 21q21.2-q21.3.}, journal = {Gene}, year = 1996, } @article{CTT100411767, author = {HIROSHI HANDA}, title = {Selective purification of DNA or RNA using single-stranded DNA aftinity latex particles}, journal = {J. Colloid Interface Sci.}, year = 1996, } @article{CTT100411768, author = {HIROSHI HANDA}, title = {Copurification of casein kinase II with transcription factor ATF/E4TF3.}, journal = {Nucleic Acids Res.}, year = 1996, } @article{CTT100411769, author = {HIROSHI HANDA}, title = {Activation of the retinoblastoma gene expression by Bcl-3 : lmplication for muscle cell differentiation.}, journal = {Oncogene}, year = 1996, } @article{CTT100411770, author = {HIROSHI HANDA}, title = {Atranscription factor with a leucine-zipper motit involved in light-depenclent inhibition of expression of the put operon in the photosynthotic bacterium phodobacter sphaeroides}, journal = {Plant cell Pysiol.}, year = 1996, } @article{CTT100411771, author = {HIROSHI HANDA}, title = {Purification and characterization of virus-like particles and pentamers produced by the expression of SV40 capsid proteins in insect cells.}, journal = {Biochim. Biophys. Acta.}, year = 1996, } @article{CTT100411772, author = {HIROSHI HANDA}, title = {Detection of amplified genomic sequences in human small-cell lung carcinoma cell lines by arbitrarily primed-PCR genomic fingerprinting.}, journal = {Human Genomis}, year = 1996, } @article{CTT100411773, author = {HIROSHI HANDA}, title = {Construction and characterization of a recombinant adenorirus vector carring the human preproinsulin gene under the control of the methallothionein gene promoter.}, journal = {Biochem. Biophys. Res. Commun.}, year = 1996, } @article{CTT100411774, author = {HIROSHI HANDA}, title = {Functional domains of transcription factor hGABP β1/E4TF1-53 required for nuclear localization and transcription activation.}, journal = {Nucleic Acids Res.}, year = 1996, } @article{CTT100464997, author = {M.Hashimoto and K.Chayama and A.Tsubota and M.Kobayashi and S.Saitou and Y.Arase and K.Ikeda and M.Kobayashi and A.Nakano and K.Takagi and H.Koike and K.Okamoto and H.Handa and H.Kumada }, title = {Typing six major hepatitis C virus genotypes by polymerase chain reaction using primers derived from nucleotide sequences of the NS5 region }, journal = {Int. Hepatol. Commun}, year = 1996, } @article{CTT100464996, author = {F.Hirano and H.Tanaka and Y.Makino and K.Okamoto and M.Hiramoto and H.Handa and I.Makino }, title = { Induction of the transcription factor AP-1 in cultured human colon adenocarcinoma cells following exposure to bile acids }, journal = {Carcinogenesis}, year = 1996, } @article{CTT100464991, author = {S.Inokuchi and H.Handa and T.Imai and H.Makuuchi and M.Kidokoro and H.Tohya and S.Aizawa and K.Shimamura and Y.Ueyama and T.Mitomi and Y.Sawada }, title = {Immortalization of human esophageal epithelial cells by a recombinant SV40-adenovirus vector }, journal = {Br. J. Cancer}, year = 1995, } @article{CTT100464992, author = {K.Araki-Sasaki and Y.Ohashi and T.Sasabe and K.Hayashi and H.Watanabe and Y.Tano and H.Handa }, title = {An SV40-immortalized human corneal epithelial cell line and its characterization. Invest }, journal = { Ophthalmol. Vis. Sci}, year = 1995, } @article{CTT100464993, author = {Y.Zhang and K.Araki-Sasaki and H.Handa and R.A.Akhtar}, title = {Effect of carbachol on phospholipase C-mediated phosphatidylinositol 4,5-bisphosphate hydrolysis,and its modulation by isoproterenol in rabbit corneal epithelial cells }, journal = { Curr. Eye Res }, year = 1995, } @article{CTT100464994, author = {K.Watanabe and F.Momose and H.Handa and K.Nagata}, title = {Interaction between influenza virus proteins and pine cone antitumor substance that inhibits the virus multiplication }, journal = { Biochem. Biophys. Res. Commun}, year = 1995, } @article{CTT100464995, author = { M.Goto and T.Shimizu and J-I.Sawada and C.Sawa and H.Watanabe and H.Ichikawa and M.Ohira and M.Ohki and H.Handa }, title = {Assignment of the E4TF1-60 gene, an Ets-related transcription factor, to human chromosome 21q21.2-q21.3 }, journal = {Gene}, year = 1995, } @article{CTT100411779, author = {半田宏}, title = {好みのタイプ}, journal = {バイオサイエンスとバイオインダストリー}, year = 1995, } @article{CTT100411778, author = {半田宏}, title = {転写因子}, journal = {炎症と免疫}, year = 1995, } @article{CTT100411764, author = {HIROSHI HANDA}, title = {cDNA library for a specific region of chromosome by a novel cDNA selection method using latex porticles.}, journal = {Gene}, year = 1995, } @article{CTT100411763, author = {HIROSHI HANDA}, title = {Purification of membrane receptors with peptide-carring affinity latex beads.}, journal = {Colloids and Surfaces B : Biointerfaces}, year = 1995, } @article{CTT100411762, author = {HIROSHI HANDA}, title = {Potentiation of glucocorticoid-mediated gene expression by the novel benzoquinone derivative(2E)-3-[5-(2,3-dimethoxy-o-methyl-1,4-benzoquinoyl)]-2-nonyl-2-propenoic acid (E3330).}, journal = {Eur. J. Pharm}, year = 1995, } @article{CTT100411761, author = {HIROSHI HANDA}, title = {Purification of transcription factor IIA using yeast TATA-binding protein affinity latex particles}, journal = {International J. Bio-Chromatography}, year = 1995, } @article{CTT100411760, author = {HIROSHI HANDA}, title = {GABP and PU.I Compete for Binding ,Yet Cooperate to Increase CD18(β┣D22┫D2 Leukocyte Integrin) transcription}, journal = {J.Biol.Chem}, year = 1995, } @article{CTT100411759, author = {HIROSHI HANDA}, title = {A Nuclear Factor (NF2d9) That Binds to the Male-Specific P450(Cyd 2d-9) Gare in Mouse Liver}, journal = {Mol.Cell.Biol.}, year = 1995, } @article{CTT100411758, author = {HIROSHI HANDA}, title = {Cell Type-Specihic Trans-Activation by the B-Myd Gene product:Repuirement of the Putative Cofactor Binding to the C-Terminal Consorved Domain}, journal = {Oncogene}, year = 1995, } @article{CTT100411757, author = {HIROSHI HANDA}, title = {Stimulation of DNA Formscription by the Replication factor From the Adenovirus Genome in a Chromation-Like Structure}, journal = {J.Biol.Chem}, year = 1995, } @article{CTT100411754, author = {HIROSHI HANDA}, title = {Silk gland factor-1 involved in the regulation of bombyx sericin-1 gene Contains fork head motif.}, journal = {J. Biol. Chem}, year = 1995, } @article{CTT100411753, author = {HIROSHI HANDA}, title = {Replication factor encoded by a putative oncogene, set, associated with myeloid leukemogenesis.}, journal = {Proc. Natl. Acad. Sci. USA}, year = 1995, } @article{CTT100411748, author = {HIROSHI HANDA}, title = {Regional mapping of two subunits of transcription factor E4TFI to human chromosome.}, journal = {Jap. J. Can. Res.}, year = 1995, } @article{CTT100411746, author = {HIROSHI HANDA}, title = {Regulation of influenza virus RNA polymerase activity by cellular and viral factors.}, journal = {Nucleic Acids Res.}, year = 1994, } @article{CTT100465043, author = {荒木かおる and 笹部哲生 and 大橋裕一 and 安田昌弘 and 半田宏 and 田野保雄 }, title = {SV40-Adenovirusレコンビナントベクタ-により不死化された   ラット角膜上皮細胞について }, journal = {日本眼科学会雑誌}, year = 1994, } @article{CTT100465042, author = {半田宏}, title = {1993年度ノ-ベル医学生理学賞}, journal = {日本評論社からだの科学 }, year = 1994, } @article{CTT100465041, author = {半田宏}, title = {1993年ノ-ベル生理学医学賞、”分断遺伝子”を発見したP.シャ-プとR.ロバ-ツ- }, journal = {現代化学}, year = 1994, } @article{CTT100465040, author = {半田宏}, title = {1993年ノ-ベル賞受賞者の業績と人柄}, journal = {科学}, year = 1994, } @article{CTT100465039, author = {半田宏}, title = {フィリップ・シャ-プ博士とリチャ-ド・ロバ-ツ博士の業績}, journal = {蛋白質核酸酵素}, year = 1994, } @article{CTT100464990, author = {E.Savoysky and T.Mizuno and Y.Sowa and H.Watanabe and J-I.Sawada and H.Nomura and Y.Ohsugi and H.Handa and T.Sakai }, title = {The retinoblastoma binding factor 1 (RBF-1) site in RB gene promoter binds preferentially E4TF1, a member of the Ets transcription factors family }, journal = {Oncogene}, year = 1994, } @article{CTT100464989, author = {J-I.Sawada and M.Goto and C.Sawa and H.Watanabe and H.Handa}, title = {Transcriptional regulation through the tetrameric complex formation of E4TF1 subunits }, journal = {EMBO J}, year = 1994, } @article{CTT100464988, author = { Y.Sumi and T.Shiroya and K.Fujimoto and T.Wada and H.Handa and H.Kawaguchi}, title = {Application of cationic latex particles for protein separation}, journal = {Colloids and Surfaces B: Biointerfaces }, year = 1994, } @article{CTT100411752, author = {半田宏}, title = {分断遺伝子の発見が与えた衝撃}, journal = {化学}, year = 1994, } @article{CTT100411751, author = {半田宏}, title = {遺伝子発現と転写因子}, journal = {メビオ}, year = 1994, } @article{CTT100411750, author = {半田宏}, title = {DNA固定化ラテックス粒子の診断薬への応用}, journal = {バイオインダストリー}, year = 1994, } @article{CTT100411747, author = {HIROSHI HANDA}, title = {Multiple nuclear localization signals of the B-myb gene product}, journal = {FEBS Lett.}, year = 1994, } @article{CTT100411745, author = {HIROSHI HANDA}, title = {Synthesis of novel optically active polymethacrylamide having L-leucine structure in the side chain}, journal = {Macromolecules}, year = 1994, } @article{CTT100411744, author = {HIROSHI HANDA}, title = {Preparation of DNA-carrying latex and purification of transcription factors with the latex.}, journal = {J. Biomater. Sci. Polymer Edn.}, year = 1994, } @article{CTT100411743, author = {HIROSHI HANDA}, title = {The retinoblastoma binding factor 1 (RBF-1) site in RB gene promoter binds preferentially E4TFI, a member of the Ets transcription factors family.}, journal = {Oncogene}, year = 1994, } @article{CTT100411742, author = {HIROSHI HANDA}, title = {Hemopoietic supportive function of human bone marrow stromal cell lines established by a recombinant SV40-adenovirus vector.}, journal = {Exp. Hematol.}, year = 1994, } @article{CTT100411732, author = {半田宏}, title = {遺伝子発現と転写因子DNAウイルスー転写調節モデル系として-}, journal = {Mebio}, year = 1994, } @article{CTT100411737, author = {HIROSHI HANDA}, title = {cDNA cloning of transcription factor E4TFI subunits with ETS and Notch motifs.}, journal = {Mol. Cell. Biol.}, year = 1993, } @article{CTT100411738, author = {HIROSHI HANDA}, title = {Studies of HIV-I protease inhibitors. I. Incorpration of a reduced peptide, simple aminoalcohol and statine analog at the specific site of substrate sequence}, journal = {Chem. Pharm. Bull.}, year = 1993, } @article{CTT100411739, author = {HIROSHI HANDA}, title = {Studies of HIV-1 protease inhibitors. II. incorporation of four types of hydroxyethylene dipeptide isosteres at the scissile site of substrate sequences.}, journal = {Chem. Pharm. Bull.}, year = 1993, } @article{CTT100411740, author = {HIROSHI HANDA}, title = {Immnortalization of rabbit corneal epithelial cells by a recombinant SV40- adenovirus vector.}, journal = {Invest. Ophthalmol. Vis. Sci.}, year = 1993, } @article{CTT100411730, author = {HIROSHI HANDA}, title = {Isolation of a cDNA encoding the largest subunit of TFIIA reveals functions important for activated transcription.}, journal = {Genes & Dev.}, year = 1993, } @article{CTT100465037, author = {半田宏}, title = {がん研究における百年史,臨床内科医会講演集 第二巻}, journal = {東京研文社}, year = 1993, } @article{CTT100465038, author = {半田宏 and 田村隆明}, title = {転写因子研究法}, journal = {羊土社}, year = 1993, } @article{CTT100464987, author = {H.Tabuchi and H.Handa and S.Hirose}, title = {Underwinding of DNA on binding of yeast TFIID to the TATA element}, journal = {Biochem. Biophys. Res. Commun}, year = 1993, } @article{CTT100411733, author = {半田宏}, title = {アテツウイルス遺伝子の転写制御}, journal = {実験医学}, year = 1993, } @article{CTT100411736, author = {HIROSHI HANDA}, title = {Novel 8-base pair Sequence(Drosophila DNA Replication-related Element)and Specific Binding Facter Involved in the Expressiorc of Drosophila Genes for DNA polymerase α and Proliferating Cell Nuclear Antigen}, journal = {J. Biol. Chem}, year = 1993, } @article{CTT100411734, author = {HIROSHI HANDA}, title = {A common trans-acting factor to the promoters of steroidogenic P-450c}, journal = {J. Biol. Chem.}, year = 1992, } @article{CTT100465030, author = {半田宏}, title = {ラテックス粒子を用いた転写因子の精製法}, journal = {実験医学}, year = 1992, } @article{CTT100411741, author = {HIROSHI HANDA}, title = {Application of cationic latex particles for protein separation.}, journal = {Colloids and Surfaces B : Biointerfaces}, year = 1992, } @article{CTT100465032, author = {猪口貞樹 and 半田宏 and 島村和男 and 城所正子 and 中村嘉彦 and 赤塚明 and 上田守三 and 正津晃 and 橋本一男 and 三富利夫 }, title = {SV40初期遺伝子導入ヒト表皮細胞の分化}, journal = {日本熱傷学会}, year = 1992, } @article{CTT100465033, author = {今井剛 and 半田宏}, title = {腎と分子生物学}, journal = {腎と透析}, year = 1992, } @article{CTT100465034, author = {和田忠士 and 半田宏}, title = {アデノウイルスの転写制御}, journal = {生物物理}, year = 1992, } @article{CTT100465035, author = {和田忠士 and 半田宏}, title = {アデノウイルスの複製と遺伝子発現「生命科学を推進する分子ウイルス学」}, journal = {蛋白質核酸酵素}, year = 1992, } @article{CTT100465036, author = {島村和男 and 猪口貞樹 and 半田宏 and 上山義人}, title = {培養ヒト表皮細胞のin vitroにおける分化増殖モデルの開発}, journal = {Medical Immunology}, year = 1992, } @article{CTT100411727, author = {HIROSHI HANDA}, title = {Direct purification of multiple ATF/E4TF3 polypeptides from HeLa all crude nuclear extracts using DNA attinity latex particles}, journal = {Anal. Biochem.}, year = 1992, } @article{CTT100464980, author = {Y.Hosaka and A.Kitamoto and M.Shimojo and K.Nakajima and Y.Imai and H.Handa and S.Kohsaka }, title = {Generation of microglia cell lines by transfection with simian virus 40 large T gene }, journal = {Neursci. Lett}, year = 1992, } @article{CTT100464981, author = {T.Hashimoto and K-I.Morohashi and T.Takayama and S-I.Honda and T.Wada and H.Handa and T.Omura }, title = {Cooperative transcription activation between Ad1, a CREB-like element, and other elements in the CYPB gene promoter }, journal = {J. Biochem}, year = 1992, } @article{CTT100464982, author = {F.Hirose and M.Yamaguchi and H.Handa and Y.Inomata and A.Matsukage}, title = {Novel 8-bp sequence (DRE) and specific binding factor (DREF) involved in the expression of Drosophila genes for DNA polymeraseαand proliferating cell nuclear antigen }, journal = {J. Biol. Chem}, year = 1992, } @article{CTT100464983, author = {T.Hashimoto and K-I.Morohashi and T.Takayama and S-I.Honda and T.Wada and H.Handa and T.Omura }, title = {Cooperative transcription activation between Ad1, a CREB-like element, and other elements in the CYPB gene promoter }, journal = {J. Biochem}, year = 1992, } @article{CTT100464984, author = {F.Hirose and M.Yamaguchi and H.Handa and Y.Inomata and A.Matsukage}, title = {Novel 8-bp sequence (DRE) and specific binding factor (DREF) involved in the expression of Drosophila genes for DNA polymeraseαand proliferating cell nuclear antigen }, journal = {J. Biol. Chem}, year = 1992, } @article{CTT100464985, author = {M.Sakurai and M.Sugano and S.Higashida and A.Kasuya and S.Miyamoto and H.Handa and T.Komai and R.Yagi and T.Nishigaki and Y.Yabe }, title = {Synthesis of HIV-1 protease inhibitors. In Peptide Chemistry 1992. (ed. N.Yanaihara) }, journal = {ESCOM}, year = 1992, } @article{CTT100464986, author = {K.Sogawa and H.Handa and A.Fujisawa-Sehara and T.Hiromasa and M.Yamane and Y.Fujii-Kuriyama }, title = {Repression of cytochrome P450c gene expression by cotransfection with adenovirus E1a DNA. In Molecular Biology of chytichrome P-450 (ed. T.Omura) }, journal = {Kyushu University Press}, year = 1992, } @article{CTT100465031, author = {半田宏}, title = {DNAアフィニティ-粒子による転写因子の精製}, journal = {生化学}, year = 1992, } @article{CTT100411735, author = {HIROSHI HANDA}, title = {Transcriptical regulation by a point mutant of adnovirus-2 E1a product lacking DNA binding activity}, journal = {J. Biol. Chem.}, year = 1992, } @article{CTT100465028, author = {半田宏}, title = {アデノウイルス感染症}, journal = {Medical Immunology}, year = 1991, } @article{CTT100464973, author = {T.Imai and H.Kawaguchi and T.Wada and H.Handa}, title = {E1A gene products stimulate in vitro transciption from the adenovirus early region 4 promoter by enhancing stable preinitiation complex }, journal = {Virus Genes}, year = 1991, } @article{CTT100464974, author = {S.Aizawa and N.Yaguchi and M.Nakano and S.Inokuchi and H.Handa and K.Toyama}, title = {Establishment of a variety bone marrow stromal cell lines by the recombinant SV40-adenovirus vector }, journal = {J. Cell. Physiol}, year = 1991, } @article{CTT100464975, author = {M.S.Sato and C.Moriyama and A.Asai and H.Handa and M.F.Rajewsky and T.Kuroki and M.Huh}, title = {Monoclonal antibody-mediated solid-phase assay of mammalian O6-alkylguanine DNA alkyltransferase activity }, journal = {Anal. Biochem}, year = 1991, } @article{CTT100464976, author = {T.Hibi and T.Fujisawa and T.Kanai and A.Akatsuka and S.Habu and H.Handa and M.Tsuchiya}, title = {Establishment of epithelial cell lines from human and mouse thymus immortalized by the 12S adenovirus E1A gene product }, journal = {Thymus}, year = 1991, } @article{CTT100464977, author = {S.Inokuchi and M.Ueda and K.Hashimoto and H.Handa and T.Mitomi}, title = {Immortalization of human epidermal keratinocytes by the recombinant SV40-adenovirus vector }, journal = {In Vitro Cell. Dev. Biol}, year = 1991, } @article{CTT100464978, author = {S.Inokuchi and M.Ueda and K.Hashimoto and H.Handa and T.Mitomi}, title = {Calcium induced differentiation of SV40 immortalized human epidermal keratinocytes cultured in defined medium }, journal = {Tokai J. Exp. Clin. Med}, year = 1991, } @article{CTT100464979, author = {H.Kawaguchi and A.Asai and Y.Ohtsuka and H.Watanabe and T.Wada and H.Handa}, title = {Purification of DNA-binding transcription factors by their selective adsorption on the affinity latex particles. In Transcription Regulation Mechanisms in Eukaryotic Genes. (ed. M.Muramatsu) }, journal = {Nakanishi Printing Co., Ltd}, year = 1991, } @article{CTT100411724, author = {HIROSHI HANDA}, title = {Different biological activities of the hetero-and homodimers formed by the 47Kd and 43Kd proteins of transcription factor ATF/E4TF3.}, journal = {J. Vitol}, year = 1991, } @article{CTT100411725, author = {HIROSHI HANDA}, title = {Negative supercoiling of DNA facilitates on interaction between tromscription factor IID and fibroin gene promoter}, journal = {Proc. Natl. Acad. Sci USA}, year = 1991, } @article{CTT100411726, author = {HIROSHI HANDA}, title = {Affinity-purification of transcription factor IIA from HeLa cell nuclear extracts.}, journal = {EMBO J.}, year = 1991, } @article{CTT100465025, author = {半田宏}, title = {ガン研究の100年史}, journal = {健康管理,保健文化社}, year = 1991, } @article{CTT100465026, author = {猪股幸雄 and 川口春馬 and 和田忠士 and 半田宏}, title = {転写制御タンパク分離精製用のDNAアフィニティ-ラテックスの改良}, journal = {高分子論文集,高分子学会}, year = 1991, } @article{CTT100465027, author = {和田忠士 and 半田宏 and 猪股幸雄 and 川口春馬}, title = {DNAアフィニティ-クロマトグラフィ-・ラテックス粒子による転写因子の精製 }, journal = {Cell Science}, year = 1991, } @article{CTT100465029, author = {半田宏}, title = {バイオテクノロジ-の最前線}, journal = {東京工業大学研究・情報交流センタ-(平成3年度東京工業大学公開講座)}, year = 1991, } @article{CTT100465022, author = {半田宏}, title = {細胞増殖と核タンパク質のリン酸化}, journal = {オンコロジア}, year = 1990, } @article{CTT100464972, author = {T.Wada and Y.Nogi and H.Handa and T.Fukasawa}, title = {Strain-specific lethal effect of adenovirus E1a protein of Saccharomyces cerevisiae }, journal = {Biochem. Biophys. Res.Commun }, year = 1990, } @article{CTT100465024, author = {半田宏}, title = {医学における遺伝子工学のトピックス}, journal = {中央区医師会雑誌}, year = 1990, } @article{CTT100465023, author = {渡辺肇 and 和田忠士 and 臼田佳弘 and 半田宏}, title = {転写調節におけるタンパク質因子間相互作用}, journal = {蛋白質核酸酵素}, year = 1990, } @article{CTT100464971, author = {H.Watanabe and T.Wada and H.Handa}, title = {Transcription factor E4TF1 contains two subunits with different functions }, journal = {EMBO J}, year = 1990, } @article{CTT100464970, author = {H.Handa and H.Watanabe and Y.Suzuki and S.Hirose}, title = {Effect of DNA supercoiling on transcription from the adenovirus early region 4 }, journal = {FEBS Lett}, year = 1989, } @article{CTT100464969, author = {K.Sogawa and H.Handa and A.Fujisawa-Sehara and T.Hiromasa and M.Yamane and Y.Fujii-Kuriyama }, title = {Repression of cytochrome P-450c gene expression by the adenovirus E1A gene products }, journal = {Eur. J. Biochem}, year = 1989, } @article{CTT100411722, author = {HIROSHI HANDA}, title = {Purification of DNA-binding transcription factors by their selective adsorption on the affinity latex panticles}, journal = {Nucleic Acids Res.}, year = 1989, } @article{CTT100465021, author = {半田宏}, title = {アデノウイルス初期遺伝子の転写制御}, journal = {実験医学}, year = 1989, } @article{CTT100411721, author = {HIROSHI HANDA}, title = {Transcription in the reverse orientation at either terminus of the adenovirus type 5 genome.}, journal = {EMBO J.}, year = 1989, } @article{CTT100464962, author = {T.Nishigaki and S.Hanaka and R.E.Kingston and H.Handa}, title = {A specific domain of the adenovirus EIV promoter is necessary to maintain susceptibility of the integrated promoter to E1A transactivation }, journal = {Mol. Cell Biol}, year = 1988, } @article{CTT100464963, author = {T.Kohama and H.Handa and K.Harigaya}, title = {A burst-promoting activity derived from the human bone marrow stromal cell line KM102 is identical to the granulocyte-macrophage colony-stimulating factor }, journal = {Exp. Hematol}, year = 1988, } @article{CTT100464964, author = {A.Abe and T.Wada and H.Handa and Y.Nogi and T.Fukasawa}, title = {Efficient usage of galactose-inducible expression vector in production of heterologus protein in yeast }, journal = {Agric.Biol.Chem }, year = 1988, } @article{CTT100464965, author = {Y.Akahori and H.Handa and K.Imai and M.Abe and K.Kameyama and M.Hibiya and H.Yasui and K.Okamura and M.Naito and H.Matsuoka and Y.Kurosawa }, title = {Sigma region located between Cμand Cδ genes of human immunoglobulin heavy chain: Possible involvement of tRNA-like structure in RNA splicing }, journal = {Nucleic Acids Res}, year = 1988, } @article{CTT100411720, author = {HIROSHI HANDA}, title = {Identification of two transcription factors that bind to specific elements in the promoter of the adonovirus early region 4.}, journal = {Mol. Cell. Biol.}, year = 1988, } @article{CTT100465018, author = {渡辺肇 and 半田宏}, title = {熱ショックタンパク質}, journal = {細胞工学}, year = 1988, } @article{CTT100465019, author = {半田宏 and 村松正美}, title = {遺伝子工学}, journal = {丸善株式会社}, year = 1988, } @article{CTT100465020, author = {半田宏}, title = {微生物実習提要}, journal = {東京大学医科学研究所学友会編,丸善株式会社}, year = 1988, } @article{CTT100465017, author = {半田宏}, title = {アデノウイルス転写の機構}, journal = {ウイルス}, year = 1987, } @article{CTT100464960, author = {S.Hanaka and T.Nishigaki and P.A.Sharp and H.Handa}, title = {Regulation of in vitro and in vivo transcription of early region IV of adenovirus type 5 by multiple cis-acting elements }, journal = {Mol. Cell. Biol}, year = 1987, } @article{CTT100465016, author = {半田宏}, title = {パルボウイルス・ベクタ-}, journal = {ウイルス,日本ウイルス学会}, year = 1987, } @article{CTT100465015, author = {渡辺肇 and 半田宏}, title = {熱ショックタンパク質と癌遺伝子}, journal = {オンコロジア,オンコロジア社}, year = 1986, } @article{CTT100465014, author = {半田宏}, title = {特異塩基配列を用いた転写制御因子の分離・精製}, journal = {学術月報}, year = 1986, } @article{CTT100464959, author = {K.Oda and M.Masuda-Murata and K.Shiroki and H.Handa}, title = {Mitogenic activity of the adenovirus type 12 E1A gene induced by hormones in rat cells }, journal = {J. Virol.}, year = 1986, } @article{CTT100465013, author = {半田宏 and 渡辺肇 and 西垣隆}, title = {アデノウイルスE4遺伝子の転写制御}, journal = {蛋白質核酸酵素}, year = 1985, } @article{CTT100464957, author = {H.Handa and K.Mizumoto and K.Oda and H.Okamoto and T.Fukasawa}, title = {Transcription of the human adenovirus E1A gene in Saccharimyces cerevisiae }, journal = {Gene}, year = 1985, } @article{CTT100464958, author = {K.Harigaya and H.Handa}, title = {Generation of functional clonal cell lines from human bone marrow stroma }, journal = {Proc. Natl. Acad. Sci. USA}, year = 1985, } @article{CTT100465010, author = {半田宏}, title = {ウイルス遺伝子による発癌機構}, journal = {日本医師会雑誌,日本医学会}, year = 1984, } @article{CTT100465009, author = {半田宏}, title = {ウイルスベクタ-の利用}, journal = {蛋白質核酸酵素}, year = 1984, } @article{CTT100464956, author = {H.Handa and P.A.Sharp}, title = {Requirement for distal upstream sequences for maximal transcription in vitro of early region IV of adenovirus }, journal = {Mol. Cell. Biol}, year = 1984, } @article{CTT100465012, author = {半田宏}, title = {動物細胞の発現調節}, journal = {細胞工学}, year = 1984, } @article{CTT100465011, author = {半田宏}, title = {癌細胞に発現する細胞周期に関与するp53遺伝子}, journal = {細胞工学,秀潤社}, year = 1984, } @article{CTT100464955, author = {M.Notake and T.Kurosaki and T.Yamamoto and H.Handa and M.Mishina and S.Numa}, title = {Sequence requirement for in vitro transcription of the human corticotropin/β-Lipotropin precursor gene }, journal = {Eur. J. Biochem}, year = 1983, } @article{CTT100411723, author = {HIROSHI HANDA}, title = {Inhibition of adenovirus early region IV transcription in vitro by purified viral 72,000 DNA binding protein}, journal = {Nature}, year = 1983, } @article{CTT100465007, author = {半田宏}, title = {アデノウイルス遺伝子のin vitro転写系}, journal = {蛋白質核酸酵素、共立出版株式会社}, year = 1982, } @article{CTT100465005, author = {半田宏}, title = {SV40遺伝子の転写}, journal = {生化学、日本生化学学会}, year = 1982, } @article{CTT100465006, author = {内田清二郎 and 余郷嘉明 and 菅野純夫 and 半田宏 and 吉池邦人 and 小田欽一郎 and 羽倉明 }, title = {パポバウイルスの最近の知見}, journal = {代謝、中山書店}, year = 1982, } @article{CTT100465004, author = {半田宏}, title = {逆転写酵素の発見}, journal = {循環、メジカルビュー社}, year = 1981, } @article{CTT100464954, author = {I.Saito and J.Sato and H.Handa and K.Shiroki and H.Shimojo}, title = {Mapping of RNAs transcribed from adenovirus type 12 early VA RNA regions }, journal = {Virology}, year = 1981, } @article{CTT100465003, author = {半田宏}, title = {ウイルス遺伝の転写-主にmRNAのプロセッシング-}, journal = {医学の歩み、医歯薬出版株式会社}, year = 1981, } @article{CTT100464952, author = {H.Handa and R.J.Kaufman and J.L.Manley and M.L.Gefter and P.A.Sharp}, title = {Transcription of SV40 DNA using mammalian cell extracts }, journal = {J. Biol. Chem}, year = 1981, } @article{CTT100464953, author = {C.L.Cepko and U.Hansen and H.Handa and P.A.Sharp}, title = {Sequential transcription-translation of SV40 using mammalian cell extracts }, journal = {Mol. Cell. Biol}, year = 1981, } @article{CTT100464947, author = {H.Handa and P.A.Sharp}, title = {Expression of early and late SV40 transcripts in the absence of protein synthesis}, journal = {J. Virol}, year = 1980, } @article{CTT100464948, author = {J.L.Manley and H.Handa and S-Y.Huang and M.L.Gefter and P.A.Sharp}, title = {Transcription of animal virus genes in vitro. In Mobilization and Reassembly of Genetic Information. (eds. W.A.Acott et al) }, journal = {Academic Press, Inc}, year = 1980, } @article{CTT100464946, author = {H.Handa and B.J.Carter}, title = {Adeno-associated virus DNA replication complexes in herpes simplex virus or adenovirus-infected cells}, journal = {J. Biol. Chem}, year = 1979, } @article{CTT100464945, author = {K.Hashimoto and H.Handa and K.Umehara and S.Sasaki}, title = { Germfree mice reared on an antigen-free diet}, journal = { Lab. Animal Science}, year = 1978, } @article{CTT100464961, author = {H.Handa and T.Toda and M.Tajima and T.Wada and H.Iida and T.Fukasawa}, title = {Expression of the human adenovirus E1A product in yeast }, journal = {Gene}, year = 1978, } @article{CTT100464943, author = {H.Handa and K.Shiroki and H.Shimojo}, title = {Isolation and characterization of KB cell lines latently infected with adeno-associated virus type 1. In Parvovirus: Replication and Biological Properties. (eds. D.C.Ward and P.Tattersall)}, journal = {Cold Spring Harbor, New York}, year = 1978, } @article{CTT100464944, author = {H.Handa and K.Shiroki and H.Shimojo}, title = {In Parvovirus: Replication and Biological Propeties. (eds. D.C.Ward and P.Tattersall)}, journal = {Cold Spring Harbor, New York}, year = 1978, } @article{CTT100464941, author = {K.Shiroki and H.Handa and H.Shimojo and S.Yano and S.Ojima and K.Fujinaga}, title = {Establishment and characterization of rat cell lines transformed by restriction endonuclease fragment of adenovirus 12 DNA}, journal = {Virology}, year = 1977, } @article{CTT100464940, author = {H.Handa and K.Shiroki and H.Shimojo}, title = {A helper function(s) for growth of adeno-associated virus in cells transformed by adenovirus 12}, journal = {Proc.Natl.Acad.Sci.USA}, year = 1977, } @article{CTT100464939, author = {H.Handa and K.Shiroki and H.Shimojo}, title = {Establishment and characterization of KB cell lines latently infected with adeno-associated virus type 1}, journal = {Virology}, year = 1977, } @article{CTT100464938, author = {H.Handa and H.shimojo}, title = {Viral DNA sysnthesisin vitro with nuclei isolated from adeno-associated virus type 1-infected cells}, journal = {Virology}, year = 1977, } @article{CTT100464942, author = {H.Handa and H.Shimojo}, title = {Isolation of the viral DNA replication complex from adeno-associated virus type 1-infected cells}, journal = {J.Virol}, year = 1977, } @article{CTT100465002, author = {半田宏}, title = {Adeno-Association Virus 1型(AAV1)の増殖の解析}, journal = {慶応医学}, year = 1976, } @article{CTT100464936, author = {H.Handa and H.Shimojo and H.Yamagushi}, title = {Multiplication of adeno-associated virus type 1 in cells coinfected with a temperature-sensitive mutant of human adeno-virus type 31}, journal = {Virology}, year = 1976, } @article{CTT100464933, author = {H.Handa and K.Shiroki and H.Shimojo}, title = {Complementation of adeno-associated virus growth with temperature-sensitive mutants of human adenovirus types 12 and 5.}, journal = {J.Gen.Virol}, year = 1975, } @inproceedings{CTT100777899, author = {坂本 聡 and Gupta Vipul and 劉 舒捷 and 安藤秀樹 and 舘野峻平 and 金子裕生 and 湯上真人 and 石井亮平 and 濡木 理 and 山口雄輝 and 半田 宏}, title = {抗炎症薬サリチル酸が示す生体内作用メカニズムの解析}, booktitle = {}, year = 2017, } @inproceedings{CTT100777377, author = {坂本 聡 and 山口 雄輝 and 半田宏}, title = {ターゲット因子の解析を基盤とする生物活性物質が示す作用機構の解明}, booktitle = {}, year = 2017, } @inproceedings{CTT100779844, author = {坂本 聡 and 伊藤 拓水 and 森 智行 and 安藤 秀樹 and 山口 雄輝 and 箱嶋 敏雄 and 半田 宏}, title = {CRBNに対するサリドマイド光学異性体の結合基盤解析}, booktitle = {}, year = 2016, } @inproceedings{CTT100779846, author = {伊藤 拓水 and 朝妻 知子 and 山本 淳一 and 安藤 秀樹 and 佐藤 智美 and 山口 雄輝 and 半田 宏}, title = {リガンド依存的ユビキチンリガーゼCRBNの制御機構}, booktitle = {}, year = 2016, } @inproceedings{CTT100777832, author = {Satoshi Sakamoto and Takumi Ito and Yuki Yamaguchi and Hideki Ando and Hiroshi Handa}, title = {Biochemical analyses of CRBN, the target protein for immunomodulatory drugs (IMiDs)}, booktitle = {}, year = 2015, } @inproceedings{CTT100777831, author = {Satoshi Sakamoto and Yuki Yamaguchi and Takumi Ito and Hiroshi Handa}, title = {Elucidation of the molecular mechanisms of action of bioactive natural products using high performance affinity beads}, booktitle = {}, year = 2015, } @inproceedings{CTT100777828, author = {坂本 聡 and 伊藤 拓水 and 安藤 秀樹 and 山口 雄輝 and 半田 宏}, title = {IMiDs標的タンパク質CRBNの生化学的解析}, booktitle = {}, year = 2015, } @inproceedings{CTT100777827, author = {坂本 聡 and 山口雄輝 and 半田 宏}, title = {アフィニティビーズを利用した生物活性物質標的タンパク質の単離・同定・評価}, booktitle = {}, year = 2015, } @inproceedings{CTT100777067, author = {曹 青福 and 陳 業熹 and 半田 宏 and 山口 雄輝}, title = {新規転写伸長因子ヒトRtf1が関与する転写制御の分子機構}, booktitle = {}, year = 2014, } @inproceedings{CTT100777063, author = {山口雄輝 and 山本淳一 and 半田宏}, title = {ヒトRNA ポリメラーゼII 転写産物のプロセシング経路の選択機構}, booktitle = {}, year = 2014, } @inproceedings{CTT100777380, author = {坂本 聡 and Vipul Gupta and 劉 舒捷 and 安藤 秀樹 and 舘野 峻平 and 金子 裕生 and 湯上 真人 and 石井 亮平 and 濡木 理 and 山口 雄輝 and 半田 宏}, title = {抗炎症薬サリチル酸の生体内作用機構の解析}, booktitle = {}, year = 2014, } @inproceedings{CTT100777379, author = {坂本 聡 and 唐澤 慧記 and 東 基記 and 笠間 健嗣 and 宮澤 啓介 and 山口 雄輝 and 半田 宏}, title = {ビタミンK2が引き起こすがん細胞のアポトーシス誘導機構の解析}, booktitle = {}, year = 2014, } @inproceedings{CTT100777059, author = {曹 青福 and 陳 業熹 and 半田 宏 and 山口 雄輝}, title = {転写伸長因子ヒトPaf1複合体が関与する転写制御の分子機構}, booktitle = {}, year = 2014, } @inproceedings{CTT100777057, author = {柴田 紘孝 and 半田 宏 and 山口 雄輝}, title = {転写伸長因子DSIFおよびNELFがES細胞の多分化能維持に果たす役割}, booktitle = {}, year = 2014, } @inproceedings{CTT100799919, author = {舩造 正英 and 伊藤 拓水 and 安藤 秀樹 and 山口 雄輝 and 半田 宏}, title = {多発性骨髄腫におけるCRBN 結合因子の探索及び解析}, booktitle = {}, year = 2013, } @inproceedings{CTT100799917, author = {飯田 結 and 伊藤 拓水 and 安藤 秀樹 and 山口 雄輝 and 半田 宏}, title = {サリドマイドターゲット分子CRBN の生化学的解析}, booktitle = {}, year = 2013, } @inproceedings{CTT100565654, author = {NOBUHIRO MATSUSHITA and Kazunori Nakagawa and Takaaki Taniguchi and HIROSHI HANDA and Masaru TADA and masanori abe and MASAHIRO YOSHIMURA}, title = {Polymer Coated Magnetic Beads for Bio-screening Containing Ferrite Nanoparticles Synthesized by Hydrothermal Treatment}, booktitle = {The 10th Intl. Conf. on Ferrites (Chengdu, China)}, year = 2008, } @inproceedings{CTT100561734, author = {Toshiyuki Tanaka and Masaru Tada and Takashi Nakagawa and Masanori Abe and Adarsh Sandhu and Hiroshi Handa}, title = {"Flow Tubular Reactor Method" for Synthesis of Spherical}, booktitle = {SMA International Conference 2008 & 5th International Symposium on Nanomanufacturing}, year = 2008, } @inproceedings{CTT100561718, author = {阿部正紀 and 中川貴 and 多田大 and SANDHUAdarsh and 半田宏}, title = {医用磁性ナノビーズの作製と診断・治療への応用}, booktitle = {臨床病理}, year = 2007, } @inproceedings{CTT100561735, author = {T. Kanemaru and T. Hara and M. Tada and T. Nakagawa and H. Handa and M. Abe}, title = {Ferrite hollow spheres, 200 nm in diameter, having continuous shell prepared by ferrite plating at low temperature for biomedical carrier application}, booktitle = {52nd Magnetism and Magnetic Materials Conference}, year = 2007, } @inproceedings{CTT100546302, author = {Kazunori NAKAGAWA and Takaaki TANIGUCHI and Nobuhiro MATSUSHITA and Hiroshi HANDA and Masanori ABE and Masahiro YOSHIMURA}, title = {Hundred-nanometer Sized Bio-Magnetic Beads with Large Magnetization Using Ferrite Nanoparticles Grown by Hydrothermal Process}, booktitle = {MMM 2007 Abstracts}, year = 2007, } @inproceedings{CTT100561719, author = {中川貴 and 田中俊行 and 島津隆一 and 志村拓真 and 金丸俊 and 黒田カルロス清一 and 多田大 and 半田宏 and 阿部正紀}, title = {バイオメディカル応用を目指したFeスピネルナノビーズの作製}, booktitle = {日本セラミックス協会第20回秋季シンポジウム講演予稿集}, year = 2007, } @inproceedings{CTT100561721, author = {金丸俊 and 原洸 and 多田大 and 中川貴 and 半田宏 and 阿部正紀}, title = {フェライトめっき反応を用いたフェライト中空ナノ粒子の低温(60℃)作製}, booktitle = {第31回日本応用磁気学会学術講演会講演概要集}, year = 2007, } @inproceedings{CTT100546285, author = {Kazunori NAKAGAWA and Takaaki TANIGUCHI and Nobuhiro MATSUSHITA and Hiroshi HANDA and Masanori ABE and Masahiro YOSHIMURA}, title = {Biomagnetic Beads Using Fe3O4 Nanparticles Grown by Hydrothermal Process}, booktitle = {IUMRS-ICMAT 2007 Abstracts}, year = 2007, } @inproceedings{CTT100561748, author = {T. Tanaka* and R. Shimazu and M. Tada and T. Nakagawa and A. Sandhu and H. Handa and M. Abe}, title = {Size control (50-150 nm) of spherical monodisperse ferrite nanoparticles for biomedical applications}, booktitle = {ISAMMA2007}, year = 2007, } @inproceedings{CTT100561746, author = {K. Okawa and T. Kanemaru and M. Tada and T. Nakagawa and Y. Hase and S Nomura and M. Ikeda and K. Nishio and H. Handa and M. Abe}, title = {Heating ability of iron oxide nanoparticles at 120-900 kHz for magnetic anticancer hyperthermia}, booktitle = {ISAMMA2007}, year = 2007, } @inproceedings{CTT100529333, author = {Abe, M. and Matsushita, N. and Tada, M. and Gokon, N. and Nishio, K. and Handa, H.}, title = {Novel Medical Ferrite Nanobeads with Bioactive Molecules Immobilized Strongly onto the Surfaces}, booktitle = {}, year = 2005, } @inproceedings{CTT100574536, author = {舟橋久景 and 田中靖紘 and 今村 佳正 and 三重正和 and 真鍋 孝司 and 田中浩士 and 高橋孝志 and 相澤益男 and 半田宏 and 小畠英理}, title = {電気化学ホモジニアスアッセイによるドラッグスクリーニング法の開発}, booktitle = {電気化学会第71回大会}, year = 2004, } @misc{CTT100533570, author = {中村栄一 and 濱口宏夫 and 半田宏}, title = {「化学の明日を考える」}, year = 2006, } @misc{CTT100533571, author = {半田宏 and 阿部正紀}, title = {「機能性磁性ビーズの構築とバイオテクノロジーへの応用(2)」}, year = 2006, } @misc{CTT100594124, author = {HIROSHI HANDA}, title = {Adeno-associated virus 1型(AAV1)の増殖の解析}, year = 1976, } @misc{CTT100699750, author = {半田宏 and 坂本聡}, title = {蛍光性ポリマー微粒子及び蛍光標識セット}, howpublished = {公開特許}, year = 2015, month = {Aug.}, note = {特願2014-030228(2014/02/20), 特開2015-155813(2015/08/27)} } @misc{CTT100696687, author = {勝亦 優 and 半田宏 and 坂本聡}, title = {粒子の単分散状態維持方法及び分析対象物の検出方法}, howpublished = {公開特許}, year = 2015, month = {June}, note = {特願2013-240897(2013/11/21), 特開2015-102337(2015/06/04)} } @misc{CTT100672996, author = {阿部正紀 and 半田宏 and 中川 貴 and 多田大 and 嶋津 隆一 and 田中 俊行}, title = {球状フェライトナノ粒子及びその製造方法}, howpublished = {登録特許}, year = 2015, month = {}, note = {特願2013-146286(2013/07/12), 特開2014-028751(2014/02/13), 特許第5733586号(2015/04/24)} } @misc{CTT100669851, author = {阿部正紀 and 半田宏 and 中川 貴 and 多田大 and 嶋津 隆一 and 田中 俊行}, title = {球状フェライトナノ粒子及びその製造方法}, howpublished = {登録特許}, year = 2015, month = {}, note = {特願2013-146285(2013/07/12), 特開2014-012632(2014/01/23), 特許第5700590号(2015/02/27)} } @misc{CTT100713471, author = {平瀬 匠 and 中山 雅人 and 半田 宏 and 坂本 聡 and 内藤 靖之}, title = {被検物質の検出システム}, howpublished = {登録特許}, year = 2017, month = {Oct.}, note = {特願2014-523750(2013/07/02), 再表2014/007248(2016/06/02), 特許第6217936号(2017/10/06)} } @misc{CTT100682131, author = {半田宏 and 坂本聡 and 河田 慎太郎}, title = {ポリマー微粒子の製造方法}, howpublished = {登録特許}, year = 2017, month = {Apr.}, note = {特願2013-071029(2013/03/29), 特開2014-193972(2014/10/09), 特許第6123053号(2017/04/14)} } @misc{CTT100690759, author = {半田宏 and 和田 忠士 and 竹田 圭 }, title = {mRNAのpoly(A)鎖および/または3'末端配列の一部を切断し、翻訳反応を抑制する技術}, howpublished = {登録特許}, year = 2016, month = {}, note = {特願2013-525673(2012/07/17), 特開(再表)2013/015152(2015/02/23), 特許第5953617号(2016/06/24)} } @misc{CTT100649183, author = {阿部正紀 and 中川 貴 and 多田大 and 半田宏 and 田中 俊之}, title = {表面修飾されたフェライト微粒子の製造方法、表面修飾されたフェライト微粒子の製造装置、フェライト微粒子の製造装置}, howpublished = {登録特許}, year = 2014, month = {}, note = {特願2012-145120(2012/06/28), 特開2012-232893(2012/11/29), 特許第5532356号(2014/05/09)} } @misc{CTT100666212, author = {今井剛 and 半田宏 and 山口雄輝}, title = {骨、関節又は歯異常症の治療物質のスクリーニング方法}, howpublished = {公開特許}, year = 2013, month = {}, note = {特願2012-140671(2012/06/22), 特開2013-188201(2013/09/26)} } @misc{CTT100667578, author = {今井剛 and 半田宏 and 山口雄輝}, title = {相乗的抗糖尿病治療剤}, howpublished = {登録特許}, year = 2016, month = {}, note = {特願2012-108729(2012/05/10), 特開2013-234159(2013/11/21), 特許第6015903号(2016/10/07)} } @misc{CTT100660988, author = {半田宏 and 畠山 士 and 坂本聡}, title = {機能性物質包含微粒子を用いたバイオセンシング方法}, howpublished = {登録特許}, year = 2016, month = {Apr.}, note = {特願2011-260624(2011/11/29), 特開2013-113735(2013/06/10), 特許第5924571号(2016/04/28)} } @misc{CTT100666469, author = {今井剛 and 半田宏}, title = {新たに同定したインスリン分泌制御因子を用いた抗糖尿病薬剤のスクリーニング法}, howpublished = {登録特許}, year = 2016, month = {}, note = {特願2012-531980(2011/09/02), 特開(再表)2012/029958(2013/10/31), 特許第5881065号(2016/02/12)} } @misc{CTT100665195, author = {今井剛 and 半田宏}, title = {膵臓β細胞増殖因子を利用した医薬組成物}, howpublished = {公開特許}, year = 2013, month = {}, note = {特願2012-521423(2011/06/13), 特開(再表)2011/162115(2013/08/19)} } @misc{CTT100648166, author = {平瀬 匠 and 勝亦 優 and 土屋 真紀子 and 星野 昭裕 and 入江 新司 and 中山 雅人 and 半田宏 and 坂本聡 and 河田 慎太郎 and 内藤 靖之}, title = {標識磁性粒子を用いた被検物質の検出方法、及び被検物質の検出システム}, howpublished = {登録特許}, year = 2014, month = {Nov.}, note = {特願2011-053415(2011/03/10), 特開2012-189453(2012/10/04), 特許第5645020号(2014/11/14)} } @misc{CTT100658249, author = {半田宏 and 畠山 士 and 坂本聡 and 岸寛}, title = {ポリマー被覆フェライト微粒子および製造方法}, howpublished = {登録特許}, year = 2015, month = {Feb.}, note = {特願2011-538254(2010/10/28), 特開(再表)2011/052205(2013/03/14), 特許第5688807号(2015/02/06)} } @misc{CTT100658248, author = {半田宏 and 安藤秀樹 and 伊藤拓水 and 堀田 健太郎}, title = {サリドマイド標的因子を利用したスクリーニング方法}, howpublished = {登録特許}, year = 2014, month = {}, note = {特願2011-537238(2010/10/18), 特開(再表)2011/049043(2013/03/14), 特許第5660578号(2014/12/12)} } @misc{CTT100640664, author = {今井 剛 and 半田宏 and 稲富 聡 and 川井 絢矢}, title = {インスリン分泌促進剤、これを主成分叉は添加した糖尿病予防・改善剤及び同食品}, howpublished = {公開特許}, year = 2012, month = {}, note = {特願2010-220786(2010/09/30), 特開2012-077004(2012/04/19)} } @misc{CTT100640659, author = {今井 剛 and 半田宏}, title = {骨形成促進剤}, howpublished = {公開特許}, year = 2012, month = {}, note = {特願2010-219371(2010/09/29), 特開2012-072095(2012/04/12)} } @misc{CTT100657645, author = {半田宏 and 土井 浩司 and 榎本輝也 and 川野 雅章}, title = {ウイルス外殻構成タンパク質被覆構造体及びその製造方法}, howpublished = {公開特許}, year = 2013, month = {}, note = {特願2011-530804(2010/08/30), 特開(再表)2011/030682(2013/02/07)} } @misc{CTT100683250, author = {半田宏 and 中西章 and 川野 雅章}, title = {生理的条件下でのウイルス粒子様構造体及びその形成方法}, howpublished = {登録特許}, year = 2014, month = {}, note = {特願2010-135520(2010/06/14), 特開2010-207246(2010/09/24), 特許第5621132号(2014/10/03)} } @misc{CTT100649193, author = {半田宏 and 安藤秀樹 and 伊藤拓水 and 堀田 健太郎}, title = {中枢神経細胞の増殖及び分化に係る中核因子を含む医薬組成物}, howpublished = {公開特許}, year = 2012, month = {}, note = {特願2011-516008(2010/05/24), 特開(再表)2010-137547(2012/11/15)} } @misc{CTT100683282, author = {半田宏 and 安藤秀樹 and 伊藤拓水 and 堀田 健太郎}, title = {中枢神経細胞の増殖及び分化に係る中核因子を含む医薬組成物}, howpublished = {登録特許}, year = 2014, month = {}, note = {特願2011-516008(2010/05/24), 特開2010-137547(2012/11/15), 特許第5645816号(2014/11/14)} } @misc{CTT100626097, author = {半田宏 and 畠山 士 and 阿部 正紀 and 今井 乾介 and 上田 政和 and 村松 俊英}, title = {センチネルリンパ節の造影剤ないし同定剤、温熱療法剤}, howpublished = {公開特許}, year = 2011, month = {}, note = {特願2009-234000(2009/10/08), 特開2011-079781(2011/04/21)} } @misc{CTT100639131, author = {半田宏 and 畠山 士 and 坂本 聡 and 望月 勇輔 and 河田 慎太郎}, title = {蛍光分子を含有するポリマー粒子およびその製造方法}, howpublished = {公開特許}, year = 2012, month = {}, note = {特願2010-528640(2009/09/10), 特開(再表)2010/029739(2012/02/02)} } @misc{CTT100677665, author = {半田宏 and 畠山 士 and 坂本聡 and 望月 勇輔 and 河田 慎太郎}, title = {蛍光分子を含有するポリマー粒子およびその製造方法}, howpublished = {登録特許}, year = 2014, month = {}, note = {特願2010-528640(2009/09/10), 特開(再表)2010/029739(2012/02/02), 特許第5574492号(2014/07/11)} } @misc{CTT100624171, author = {阿部正紀 and 中川 貴 and 多田 大 and 山本 修平 and 半田宏}, title = {磁気温熱療法用発熱体および製造方法}, howpublished = {公開特許}, year = 2011, month = {}, note = {特願2009-181597(2009/08/04), 特開2011-032238(2011/02/17)} } @misc{CTT100617116, author = {半田宏 and 阿部正紀 and 畠山 士 and 坂本 聡 and 多田大 and 岸 寛 and 西尾 広介 and 北 善紀}, title = {磁性中空粒子およびその製造方法}, howpublished = {公開特許}, year = 2010, month = {}, note = {特願2009-054774(2009/03/09), 特開2010-208875(2010/09/24)} } @misc{CTT100677662, author = {半田宏 and 畠山 士 and 坂本聡 and 政池 由佳 and 西尾 広介 and 北 善紀 and 阿部正紀 and 岸寛}, title = {表面被覆無機物粒子の製造方法}, howpublished = {登録特許}, year = 2014, month = {}, note = {特願2009-524516(2008/07/25), 特開(再表)2009/014201(2010/10/07), 特許第5569837号(2014/07/04)} } @misc{CTT100666184, author = {阿部正紀 and 半田宏 and 中川 貴 and 多田大 and 嶋津 隆一 and 田中 俊行}, title = {球状フェライトナノ粒子の製造方法}, howpublished = {登録特許}, year = 2013, month = {}, note = {特願2007-340903(2007/12/28), 特開2008-201666(2008/09/04), 特許第5353004号(2013/09/06)} } @misc{CTT100587139, author = {阿部正紀 and 中川 貴 and 多田大 and 半田宏 and 金丸 俊}, title = {低沸点化合物内包中空微粒子}, howpublished = {公開特許}, year = 2009, month = {}, note = {特願2007-234572(2007/09/10), 特開2009-067684(2009/04/02)} } @misc{CTT100587131, author = {阿部正紀 and 中川 貴 and 多田大 and 半田宏 and 金丸 俊}, title = {フェライト中空微粒子の製造方法}, howpublished = {公開特許}, year = 2009, month = {}, note = {特願2007-234573(2007/09/10), 特開2009-067606(2009/04/02)} } @misc{CTT100587165, author = {阿部正紀 and 中川 貴 and 多田大 and 半田宏 and 田中 俊之}, title = {フェライト微粒子の製造方法、フェライト微粒子、及びフェライト微粒子の製造装置}, howpublished = {登録特許}, year = 2014, month = {}, note = {特願2007-224744(2007/08/30), 特開2009-057230(2009/03/19), 特許第5504399号(2014/03/28)} } @misc{CTT100666186, author = {半田宏 and 榎本 輝也 and 井上 隆昌 and 西尾 広介 and 澤田 航 and 竹山 敏久 and 上田 栄一 and 西脇 州}, title = {ウイルス粒子様構造体およびそれを含有する製剤}, howpublished = {登録特許}, year = 2013, month = {}, note = {特願2008-509810(2007/03/29), 特開(再表)2007/116808(2009/08/20), 特許第5364876号(2013/09/20)} } @misc{CTT100573031, author = {半田宏 and 澤 智華 and 廣田 雅隆 and 山田 丈}, title = {ウイルス感染阻害薬のスクリーニング法及びビスフォスフォネートを含む感染阻害薬}, howpublished = {公開特許}, year = 2008, month = {}, note = {特願2006-311865(2006/11/17), 特開2008-125391(2008/06/05)} } @misc{CTT100572768, author = {半田宏 and 阿部正紀 and 西尾 広介 and 北 善紀}, title = {蛍光機能具備磁性ポリマー粒子とその製造方法}, howpublished = {登録特許}, year = 2012, month = {}, note = {特願2006-313493(2006/11/20), 特開2008-127454(2008/06/05), 特許第5156944号(2012/12/21)} } @misc{CTT100573114, author = {半田宏 and 山本 法明}, title = {アデノ随伴ウイルスのITRをもつDNAのヒト第19番染色体への組込み部位の制御方法}, howpublished = {公開特許}, year = 2008, month = {}, note = {特願2006-263018(2006/09/27), 特開2008-079539(2008/04/10)} } @misc{CTT100573160, author = {半田宏 and 鷲田 尚洋 and 小山内 敬 and 木村 幸恵}, title = {自己免疫疾患の予防及び/又は治療剤の有効成分の同定方法}, howpublished = {公開特許}, year = 2007, month = {}, note = {特願2006-050851(2006/02/27), 特開2007-228808(2007/09/13)} } @misc{CTT100573311, author = {半田宏 and 小倉 裕次}, title = {TFII-Iを利用したスクリーニング方法}, howpublished = {公開特許}, year = 2007, month = {}, note = {特願2005-379612(2005/12/28), 特開2007-175019(2007/07/12)} } @misc{CTT100573090, author = {半田宏 and 岩崎 時男 and 安野 寛}, title = {蛋白質スクリーニング装置}, howpublished = {登録特許}, year = 2011, month = {}, note = {特願2005-335469(2005/11/21), 特開2007-139635(2007/06/07), 特許第4862121号(2011/11/18)} } @misc{CTT100573322, author = {半田宏 and 安野 寛}, title = {ノズルピッチ可変型多連ノズルユニット}, howpublished = {登録特許}, year = 2011, month = {}, note = {特願2005-335477(2005/11/21), 特開2007-139636(2007/06/07), 特許第4747230号(2011/05/27)} } @misc{CTT100573361, author = {半田宏 and 阿部正紀 and 郷右近 展之 and 西尾 広介}, title = {有機物質とフェライト粒子とを有する複合粒子及びその製造方法}, howpublished = {公開特許}, year = 2007, month = {}, note = {特願2005-261823(2005/09/09), 特開2007-070195(2007/03/22)} } @misc{CTT100573353, author = {半田宏 and 飯泉 陽介 and 笹川 千尋}, title = {病原性大腸菌感染症の予防治療薬のスクリーニング法}, howpublished = {公開特許}, year = 2007, month = {}, note = {特願2005-246009(2005/08/26), 特開2007-057477(2007/03/08)} } @misc{CTT100573212, author = {半田宏 and 阿部正紀 and 池田 森人 and 西尾 広介}, title = {表面修飾無機微粒子の製造方法および表面修飾無機微粒子}, howpublished = {公開特許}, year = 2006, month = {}, note = {特願2005-104699(2005/03/31), 特開2006-282582(2006/10/19)} } @misc{CTT100572832, author = {半田宏 and 阿部正紀 and 郷右近 展之 and 池田 森人 and 西尾 広介}, title = {マグネタイト微粒子の製造方法}, howpublished = {登録特許}, year = 2010, month = {}, note = {特願2005-035257(2005/02/10), 特開2006-219353(2006/08/24), 特許第4621911号(2010/11/12)} } @misc{CTT100573229, author = {阿部正紀 and 半田宏 and 西開 宏史}, title = {ポリマー被覆磁性ビーズおよびその製造方法}, howpublished = {公開特許}, year = 2006, month = {}, note = {特願2004-322819(2004/11/05), 特開2006-131771(2006/05/25)} } @phdthesis{CTT100594124, author = {HIROSHI HANDA}, title = {Adeno-associated virus 1型(AAV1)の増殖の解析}, school = {慶応義塾大学大学院医学研究科}, year = 1976, }