@book{CTT100874637, author = {三木卓幸 and 橋本匡浩 and 三原久和}, title = {細胞内でタンパク質を集積させるペプチドタグの開発}, publisher = {}, year = 2022, } @book{CTT100874643, author = {堤 浩 and 三原 久和}, title = {薬剤−ペプチドコンジュゲートとペプチド創薬}, publisher = {化学同人}, year = 2021, } @book{CTT100856200, author = {三木卓幸 and 三原久和}, title = {自己組織化ペプチドの設計と利用}, publisher = {東京化学同人}, year = 2020, } @book{CTT100773788, author = {堤 浩 and 三原久和}, title = {化学修飾ペプチドファージライブラリの構築と標的タンパク質に対するリガンドスクリーニング}, publisher = {技術情報協会}, year = 2017, } @book{CTT100773787, author = {堤 浩 and 三原久和}, title = {ペプチド立体構造の設計と機能}, publisher = {シーエムシー出版}, year = 2017, } @book{CTT100785178, author = {堤浩 and 三原久和}, title = {自己組織化現象を利用したペプチド性足場材料の開発}, publisher = {}, year = 2016, } @book{CTT100744040, author = {Amir Syahir and Kinya Tomizaki and Kotaro Kajikawa and Hisakazu Mihara}, title = {Anomalous Reflection of Gold: A Novel Platform for Biochips}, publisher = {Humana Press}, year = 2016, } @book{CTT100744041, author = {Kenji Usui and Kinya Tomizaki and Hisakazu Mihara}, title = {A Cell Microarray Format: A Peptide Release System Using a Photo-Cleavable Linker for Cell Toxicity and Cell Uptake Analysis}, publisher = {Humana Press}, year = 2016, } @book{CTT100785179, author = {堤浩 and 三原久和}, title = {生体分子解析・細胞解析に向けた設計ペプチドチップ}, publisher = {}, year = 2015, } @book{CTT100752780, author = {Jeffrey Cross and KIKUO KISHIMOTO and Masahiko Hara and Hisakazu Mihara}, title = {Overview on the "Tokyo Institute of Technology International Research Opportunities Program (TiROP)" - Season One: 2012}, publisher = {ASEE}, year = 2013, } @book{CTT100598277, author = {Kenji Usui and Kin-ya Tomizaki and Hisakazu Mihara}, title = {A Designed Peptide Chip: Protein Fingerprinting Technology with a Dry Peptide Array and Statistical Data mining}, publisher = {Humana Press}, year = 2009, } @book{CTT100598272, author = {臼井健二 and 富崎欣也 and 三原久和}, title = {プロテインチップデバイス}, publisher = {エヌ・ティー・エス}, year = 2009, } @book{CTT100598268, author = {Kin-ya Tomizaki and Kenji Usui and Hisakazu Mihara}, title = {Proteins:Array-Based Techniques}, publisher = {John Wiley & Sons, Inc}, year = 2008, } @book{CTT100598266, author = {三原久和 and 梶原将 and 湯浅英哉 and 小畠英理}, title = {バイオ系のための基礎化学問題集}, publisher = {講談社サイエンティフィック}, year = 2008, } @book{CTT100552146, author = {三原久和 and 高橋剛 and 富崎欣也}, title = {とことんやさしい タンパク質の本、東京工業大学大学院生命理工学研究科編、29.ペプチドは小さなタンパク質、46.人工タンパク質の分子設計、51.プロテインチップでタンパク質を検出}, publisher = {日本工業新聞社}, year = 2007, } @book{CTT100552153, author = {富崎欣也 and 三原久和}, title = {ペプチドチップ}, publisher = {シーエムシー出版}, year = 2007, } @book{CTT100552152, author = {富崎欣也 and 三原久和}, title = {プロテインチップの開発 新しいDNAチップの科学と応用}, publisher = {講談社サイエンティフィック}, year = 2007, } @book{CTT100552147, author = {三原久和 and 小畠英理 and 馬場嘉信}, title = {ナノバイオ計測の実際}, publisher = {講談社}, year = 2007, } @book{CTT100387439, author = {三原久和訳}, title = {ケミカルバイオロジーの基礎,生命科学の新しいコンセプト}, publisher = {化学同人}, year = 2004, } @book{CTT100387447, author = {高橋 剛 and 三原久和}, title = {図解バイオ活用技術のすべて,6-2自己組織化ペプチド}, publisher = {(東京工業大学大学院生命理工学研究科編)工業調査会}, year = 2004, } @book{CTT100387444, author = {富崎欣也 and 三原久和}, title = {図解バイオ活用技術のすべて,5-2プロテインチップ}, publisher = {(東京工業大学大学院生命理工学研究科編)工業調査会}, year = 2004, } @book{CTT100450932, author = {小幡谷育夫 and 三原久和}, title = {ペプチド立体構造の設計}, publisher = {シリーズ・ニューバイオフィジックスII,共立出版}, year = 2001, } @book{CTT100506676, author = {S. Matsumura and A. Ueno and H. Mihara}, title = {Construction of Two-Stranded a-Helix Peptides with L-a-Nucleobase Amino Acids}, publisher = {Peptide Science 2000}, year = 2001, } @book{CTT100506675, author = {T. Takahashi and I. Kumagai and K.Hamasaki and A. Ueno and H. Mihara}, title = {Design of Peptides with L-a-Nucleobase Amino Acids and Their Selective Recognition of RNA }, publisher = {Peptide Science 2000}, year = 2001, } @book{CTT100506679, author = {三原久和}, title = {機能性ポリペプチド:タンパク質のデノボデザイン}, publisher = {化学フロンティア4, 生命化学のニューセントラルドグマ 化学同人}, year = 2001, } @book{CTT100436759, author = {三原久和}, title = {蛍光スペクトロメトリー、円二色性スペクトロメトリー、マススペクトロメトリー}, publisher = {バイオ機器分析入門 相澤益男、山田秀徳編、講談社サイエンティフィック、東京}, year = 2000, } @article{CTT100926255, author = {Takayuki Miki and Masahiro Hashimoto and Hiroki Takahashi and Masatoshi Shimizu and Sae Nakayama and Tadaomi Furuta and Hisakazu Mihara}, title = {De novo designed YK peptides forming reversible amyloid for synthetic protein condensates in mammalian cells}, journal = {Nat. Commun.}, year = 2024, } @article{CTT100874477, author = {Takayuki Miki and Keigo Kajiwara and Sae Nakayama and Masahiro Hashimoto and Hisakazu Mihara}, title = {Effects of Hydrophobic Residues on the Intracellular Self-Assembly of De Novo Designed Peptide Tags and Their Orthogonality}, journal = {ACS Synthetic Biology}, year = 2022, } @article{CTT100874642, author = {Hisakazu Mihara}, title = {Construction of Functional Peptides Based on De Novo Design Approaches}, journal = {Peptide Science 2021}, year = 2022, } @article{CTT100863737, author = {Takayuki Miki and Masahiro Hashimoto and Taichi Nakai and Hisakazu Mihara}, title = {A guide-tag system controlling client enrichment into Y15 peptide-based granules for an in-cell protein recruitment assay}, journal = {Chemical Communications}, year = 2021, } @article{CTT100874479, author = {Jyh Yea Chia and Takayuki Miki and Hisakazu Mihara and Hiroshi Tsutsumi}, title = {Biofunctional supramolecular hydrogels fabricated from a short self-assembling peptide modified with bioactive sequences for the 3D culture of breast cancer MCF-7 cells}, journal = {Bioorganic & Medicinal Chemistry}, year = 2021, } @article{CTT100852347, author = {Takayuki Miki and Taichi Nakai and Masahiro Hashimoto and Keigo Kajiwara and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Intracellular artificial supramolecules based on de novo designed Y15 peptides}, journal = {Nature Communications}, year = 2021, } @article{CTT100852348, author = {Hiroshi Tsutsumi and Kunifumi Tanaka and Jyh Yea Chia and Hisakazu Mihara}, title = {Short self‐assembling peptides with a urea bond: A new type of supramolecular peptide hydrogel materials}, journal = {Peptide Science}, year = 2021, } @article{CTT100856132, author = {Masahiro Hashimoto and Takayuki Miki and Iou Ven Chang and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Selection of fluorescent biosensors against galectin-3 from an NBD-modified phage library displaying designed α-helical peptides}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2021, } @article{CTT100837820, author = {Teerapat Anananuchatkul and Hiroshi Tsutsumi and Takayuki Miki and Hisakazu Mihara.}, title = {hDM2 Protein-Binding Peptides Screened from Stapled alpha-Helical Peptide Phage Display Libraries with Different Types of Staple Linkers.}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2020, } @article{CTT100839486, author = {Yusuke Maeda and Toshiki Sawada and Tsuyoshi Takahashi and Hideya Yuasa and Hisakazu Mihara}, title = {Affinity Control of Monosaccharide Conjugated Peptides against Lectins with a Set of Amino Acid Substitutions on α‑Helical Structure}, journal = {Bioconjugate Chem.}, year = 2020, } @article{CTT100837826, author = {H. Tsutsumi and D. Matsubara and H. Mihara.}, title = {Functionalization of Self-assembling Peptide Materials Using Molecular Recognition of Supramolecular Peptide Nanofibers.}, journal = {Polymer Journal}, year = 2020, } @article{CTT100835142, author = {Teerapat Anananuchatkul and Iou Ven Chang and Takayuki Miki and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Construction of a Stapled α‑Helix Peptide Library Displayed on Phage for the Screening of Galectin-3-Binding Peptide Ligands}, journal = {ACS Omega}, year = 2020, } @article{CTT100809767, author = {Kazuto Fukunaga and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Self-Assembling Peptides as Building Blocks of Functional Materials for Biomedical Applications.}, journal = {Bulletin of the Chemical Society of Japan}, year = 2019, } @article{CTT100773785, author = {H.Tsutsumi and M. Kawamura and H. Mihara}, title = {Osteoblastic Differentiation on Hydrogels Fabricated from Ca2+-Responsive Self-Assembling Peptides Functionalized with Bioactive Peptides}, journal = {Bioorganic & Medicinal Chemistry}, year = 2018, } @article{CTT100773753, author = {H.Tsutsumi and T. Shirai and H. Ohkusa and H. Mihara}, title = {Gold Nanoparticles Conjugated with Glycopeptides for Lectin Detection and Imaging on Cell Surface}, journal = {Protein & Peptide Letters}, year = 2018, } @article{CTT100773752, author = {A. Syahir and K. Kajikawa and H. Mihara}, title = {Signal Enhancement Strategies for Refractive Index-Sensitive Nanobiosensor}, journal = {Protein Peptide Lett.}, year = 2018, } @article{CTT100773750, author = {I.V. Chang and H.Tsutsumi and H. Mihara}, title = {Screening for Concanavalin A Binders from a Mannose-modified α-Helix Peptide Phage Library}, journal = {Molecular BioSystems}, year = 2017, } @article{CTT100777814, author = {Kenji Usui and Masayasu Mie and Takashi Andou and Hisakazu Mihara and Eiry Kobatake}, title = {Fluorescent and luminescent fusion proteins for analyses of amyloid beta peptide aggregation}, journal = {Journal of Peptide Science}, year = 2017, } @article{CTT100788725, author = {堤浩 and 澤田敏樹 and 三原久和}, title = {自己集合性ペプチドナノファイバーを用いたナノバイオ材料の創製}, journal = {Kobunshi Ronbunshu}, year = 2017, } @article{CTT100712221, author = {Kazuto Fukunaga and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Cell Differentiation on Disk- and String-Shaped Hydrogels Fabricated from Ca(2+) Rresponsive Self-Assembling Peptides.}, journal = {Biopolymers}, year = 2016, } @article{CTT100809782, author = {Megumi Kawamura and Kazuto Fukunaga and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Cell Proliferation and Differentiation on Functionalized Self-Assembling Peptide Hydrogels.}, journal = {Peptide science}, year = 2016, } @article{CTT100712222, author = {Hiroshi Tsutsumi and Kazuhiko Nakano and Hisakazu Mihara}, title = {Dihydrofolate Reductase Inhibitory Peptides Screened from a Structured Designed β-Loop Peptide Library Displayed on Phage}, journal = {Molecular BioSystems}, year = 2015, } @article{CTT100721383, author = {Amir Syahir and Kenji Usui and Kin-ya Tomizaki and Kotaro Kajikawa and Hisakazu Mihara}, title = {Label and Label-free Detection Techniques for Protein Microarrays}, journal = {Microarrays}, year = 2015, } @article{CTT100712615, author = {Kenji Usui and Kikuchi and Masayasu and Eiry and Hisakazu}, title = {Cellular differentiation assessments by measuring the degree of cellular internalization and membrane adsorption using designed peptides}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2014, } @article{CTT100677099, author = {Ji Yang and Tadaomi Furuta and Minoru Sakurai and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {A Computational Study of the Interaction of Amphiphilic α-Helical Cell-Penetrating Peptides with Heparan Sulfate}, journal = {Bull. Chem. Soc. Jpn.}, year = 2014, } @article{CTT100679313, author = {Toshiki Sawada and Sungmin Kang and junji watanabe and Hisakazu Mihara and Takeshi Serizawa}, title = {Hybrid Hydrogels Composed of Regularly Assembled Filamentous Viruses and Gold Nanoparticles}, journal = {Acs Macro Letters}, year = 2014, } @article{CTT100673035, author = {Ji Yang and Hiroshi Tsutsumi and Tadaomi Furuta and Minoru Sakurai and Hisakazu Mihara}, title = {Interaction of Amphiphilic α-Helical Cell-Penetrating Peptides with Heparan Sulfate}, journal = {Org. Biomol. Chem.}, year = 2014, } @article{CTT100712224, author = {Hyejin Park and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Cell-Selective Intracellular Drug Delivery Using Doxorubicin and α-Helical Peptides Conjugated to Gold Nanoparticles}, journal = {Biomaterials}, year = 2014, } @article{CTT100669331, author = {Amir Syahir and Kotaro Kajikawa and Hisakazu Mihara}, title = {Enhanced refractive index sensitivity for anomalous reflection of gold to improve performance of bio-molecular detection}, journal = {Sensors and Actuators B (Chemical)}, year = 2014, } @article{CTT100712227, author = {Kazuto Fukunaga and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Self-Assembling Peptide Nanofibers Promoting Cell Adhesion and Differentiation}, journal = {Biopolymers}, year = 2013, } @article{CTT100712231, author = {Kanako Arai and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {A Monosaccharide-Modified Peptide Phage Library for Screening of Ligands to Carbohydrate-Binding Proteins}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2013, } @article{CTT100712229, author = {Hyejin Park and Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Cell Penetration and Cell-Selective Drug Delivery Using -Helix Peptides Conjugated with Gold Nanoparticles}, journal = {Biomaterials}, year = 2013, } @article{CTT100663021, author = {T. Sawada and Hisakazu Mihara and Takeshi Serizawa}, title = {Peptides as New Smart Bionanomaterials: Molecular-Recognition and Self-Assembly Capabilities}, journal = {Chemical Record}, year = 2013, } @article{CTT100660672, author = {Kenji Usui and T. Kikuchi and M. Mie and EIRY KOBATAKE and Hisakazu Mihara}, title = {Systematic screening of the cellular uptake of designed alpha-helix peptides}, journal = {Bioorganic & Medicinal Chemistry}, year = 2013, } @article{CTT100660628, author = {Takashi Kakiyama and K. Usui and K. Y. Tomizaki and M. Mie and EIRY KOBATAKE and Hisakazu Mihara}, title = {A peptide release system using a photo-cleavable linker in a cell array format for cell-toxicity analysis}, journal = {Polymer Journal}, year = 2013, } @article{CTT100712232, author = {Hiroshi Tsutsumi and Hiroyuki Ohkusa and Hyejin Park and Tsuyoshi Takahashi and HIDEYA YUASA and Hisakazu Mihara}, title = {Gold Nanoparticles Conjugated with Monosaccharide-modified Peptide for Lectin Detection}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2012, } @article{CTT100644168, author = {Amir Syahir and Kotaro Kajikawa and Hisakazu Mihara}, title = {Sensitive Detection of Small Molecule-Protein Interactions on a Metal-Insulator-Metal Label-Free Biosensing Platform}, journal = {Chemistry An Asian Journal}, year = 2012, } @article{CTT100643220, author = {T. Sawada and M. Tsuchiya and T. Takahashi and Hiroshi Tsutsumi and H. Mihara}, title = {Cell-Adhesive Hydrogels Composed of Peptide Nanofibers Responsive to Biological Ions}, journal = {Polymer Journal}, year = 2012, } @article{CTT100643217, author = {T. Sawada and H. Mihara}, title = {Dense surface functionalization using peptides that recognize differences in organized structures of self-assembling nanomaterials}, journal = {Molecular Biosystems}, year = 2012, } @article{CTT100660671, author = {Kenji Usui and Takashi Kakiyama and K. Tomizaki and M. Mie and EIRY KOBATAKE and Hisakazu Mihara}, title = {Cell fingerprint patterns using designed alpha-helical peptides to screen for cell-specific toxicity}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2011, } @article{CTT100643215, author = {T. Sawada and K. Ishiguro and T. Takahashi and H. Mihara}, title = {A novel beta-loop scaffold of phage-displayed peptides for highly specific affinities}, journal = {Molecular Biosystems}, year = 2011, } @article{CTT100643216, author = {T. Sawada and K. Ishiguro and T. Takahashi and H. Mihara}, title = {A Novel Peptide Array Using a Phage Display System for Protein Detection}, journal = {Chemistry Letters}, year = 2011, } @article{CTT100660675, author = {M. Suzuki and T. Takahashi and J. Sato and M. Mie and EIRY KOBATAKE and Hisakazu Mihara}, title = {Designed Short Peptides that Form Amyloid-Like Fibrils in Coassembly with Amyloid beta-Peptide (A beta) Decrease the Toxicity of A beta to Neuronal PC12 Cells}, journal = {Chembiochem}, year = 2010, } @article{CTT100600220, author = {A. Syahir and H. Mihara and K. Kajikawa}, title = {A New Optical Label-Free Biosensing Platform Based on a Metal-Insulator-Metal Structure}, journal = {Langmuir}, year = 2010, } @article{CTT100599322, author = {Tempei Shimizu and Yasushi Kanamori and Takao Furuki and Takahiro Kikawada and Takashi Okuda and Tsuyoshi Takahashi and Hisakazu Mihara and Minoru Sakurai}, title = {Desiccation-induced structuralization and glass formation of Group3 LEA protein model peptides}, journal = {Biochemistry}, year = 2010, } @article{CTT100660660, author = {M. Nakamura and M. Mie and Hisakazu Mihara and M. Nakamura and EIRY KOBATAKE}, title = {Construction of a Multi-Functional Extracellular Matrix Protein That Increases Number of N1E-115 Neuroblast Cells Having Neurites}, journal = {Journal of Biomedical Materials Research Part B-Applied Biomaterials}, year = 2009, } @article{CTT100643229, author = {Toshiki Sawada and Tsuyoshi Takahashi and Hisakazu Mihara}, title = {Affinity-Based Screening of Peptides Recognizing Assmbly Stated of Self-Assembling Peptide Nanomaterials}, journal = {Journal of the American Chemical Society}, year = 2009, } @article{CTT100591030, author = {Tsuyoshi Takahashi and Kosuke Tada and HISAKAZU MIHARA}, title = {RNA aptamers selected against amyloid β-peptide (Aβ) inhibit the aggregation of Aβ}, journal = {Molecular Biosystems}, year = 2009, } @article{CTT100571329, author = {Amir Syahir and Kin-ya Tomizaki and Kotaro Kajikawa and Hisakazu Mihara}, title = {Poly(amidoamine)-Dendrimer-Modified Gold Surfaces for Anomalous Reflection of Gold To Detect Biomolecular Interactions}, journal = {Langmuir}, year = 2009, } @article{CTT100591035, author = {Mariejoy Therese Jumawid and Tsuyoshi Takahashi and Toshimasa Yamazaki and Hiroshi Ashigai and HISAKAZU MIHARA}, title = {Selection and structural analysis of de novo proteins from an α3β3 genetic library}, journal = {Protein Science}, year = 2009, } @article{CTT100591029, author = {Tsuyoshi Takahashi and HISAKAZU MIHARA}, title = {Peptide and Protein Mimetics Inhibiting Amyloid β-Peptide Aggregation}, journal = {Accounts of Chemical Research}, year = 2008, } @article{CTT100660683, author = {M. Nakamura and M. Mie and Hisakazu Mihara and M. Nakamura and EIRY KOBATAKE}, title = {Construction of multi-functional extracellular matrix proteins that promote tube formation of endothelial cells}, journal = {Biomaterials}, year = 2008, } @article{CTT100552132, author = {T. Takahashi and K. Ohta and H. Mihara}, title = {Embedding the Amyloid β-Peptide Sequence in Green Fluorescent Protein Inhibits Aβ Oligomerization}, journal = {ChemBioChem}, year = 2007, } @article{CTT100552133, author = {K.-Y. Tomizaki and HISAKAZU MIHARA}, title = {Phosphate-Mediated Molecular Memory Driven by Two Different Protein Kinases as Information Input Elements}, journal = {J. Am. Chem. Soc.}, year = 2007, } @article{CTT100552126, author = {S. Watanabe and K.-Y. Tomizaki and Tsuyoshi Takahashi and K. Usui and K. Kajikawa and HISAKAZU MIHARA}, title = {Interactions Between Peptides Containing Nucleobase Amino Acids and T7 Phages Displaying S. cerevisiae Proteins}, journal = {Biopolymers (Peptide Science)}, year = 2007, } @article{CTT100552144, author = {J. Sato and Tsuyoshi Takahashi and H. Oshima and S. Matsumura and HISAKAZU MIHARA}, title = {Design of Peptides That Form Amyloid-like Fibrils Capturing Amyloid β1-42 Peptides.}, journal = {Chem. Eur. J.}, year = 2007, } @article{CTT100552124, author = {K. Usui and K.-Y. Tomizaki and HISAKAZU MIHARA}, title = {Screening of α-Helical Peptide Ligands Controlling a Calcineurin-Phosphatase Activity}, journal = {Bioorg. Med. Chem. Lett.}, year = 2007, } @article{CTT100564700, author = {Tsuyoshi Takahashi and Yana Dewi and HISAKAZU MIHARA}, title = {Utilization of L-α-Nucleobase Amino Acids (NBAs) as a Protein Engineering Tool: Construction of NBA Modified HIV-1 Protease Analogues and Enhancement of Dimerization Induced by Nucleobase Interaction}, journal = {ChemBioChem}, year = 2006, } @article{CTT100528148, author = {S. Sano and K.-Y. Tomizaki and K. Usui and H. Mihara}, title = {A PNA-DNA hybridization chip approach for the detection of beta-secretase activity}, journal = {Bioorg. Med. Chem. Lett.}, year = 2006, } @article{CTT100528150, author = {T. Kawasaki and K. Asaoka and H. Mihara and Y. Okahata}, title = {Nonfibrous β-Structured Aggregation of an Aβ Model Peptide (Ad-2α) on GM1/DPPC Mixed Monolayer}, journal = {Surfaces J. Colloid Interface Sci.}, year = 2006, } @article{CTT100528151, author = {K. Usui and K.-Y. Tomizaki and T. Ohyama and K. Nokihara and H. Mihara}, title = {A Novel Peptide Microarray for Protein Detection and Analysis Utilizing a Dry Peptide Array System}, journal = {Mol. BioSyst.}, year = 2006, } @article{CTT100528152, author = {B. Gyurcsik and H. Haruki and T. Takahashi and H. Mihara and K. Nagata}, title = {Binding Modes of the Precursor of Adenovirus Major Core Protein VII to DNA and Template Activating Factor I: Implication for the Mechanism of Remodeling of the Adenovirus Chromatin}, journal = {Biochemistry}, year = 2006, } @article{CTT100528153, author = {T. Takahashi and D. Yana and H. Mihara}, title = {Utilization of L-alpha-Nucleobase Amino Acids (NBAs) as Protein Engineering Tools: Construction of NBA-Modified HIV-1 Protease Analogues and Enhancement of Dimerization Induced by Nucleobase Interaction}, journal = {ChemBioChem}, year = 2006, } @article{CTT100528156, author = { S. Matsumura and S. Uemura and H. Mihara}, title = {Metal-triggered Nanofiber Formation of His-containing beta-Sheet Peptide}, journal = {Supramolec. Chem.}, year = 2006, } @article{CTT100528158, author = {K. Usui and K.-Y. Tomizaki and H. Mihara}, title = {Protein-fingerprint data mining of a designed alpha-helical peptide array}, journal = {Mol. BioSyst.}, year = 2006, } @article{CTT100552119, author = {K.-Y. Tomizaki and HISAKAZU MIHARA}, title = {Rational design of homogenous protein kinase assay platforms that allow both fluorometric and colorimetric signal readouts}, journal = {Mol. BioSyst.}, year = 2006, } @article{CTT100404909, author = {S. Matsumura and S. Uemura and H. Mihara}, title = {Construction of Biotinylated Ppeptide Nanotubes for Arranging Proteins}, journal = { Mol. BioSyst.}, year = 2005, } @article{CTT100404911, author = {Y. Nagai and T. Nakanishi and H. Okamoto and K. Takeda and Y. Furukawa and K. Usui and H. Mihara}, title = {IR Study on Stacking Manner of Peptide Nanorings in Peptide Nanotubes}, journal = { Jpn J. Appl. Phys.}, year = 2005, } @article{CTT100404915, author = {H. Okamoto and T. Yamada and H. Miyazaki and T. Nakanishi and K. Takeda and K. Usui and I. Obataya and H. Mihara and H. Azehara and W.Mizutani and K. Hashimoto and H. Yamaguchi and Y.Hirayama }, title = {Difference in Self-Assembling Morphology of Peptide Nanorings}, journal = {Jpn J. Appl. Phys.}, year = 2005, } @article{CTT100404917, author = {S. Watanabe and K. Usui and K.-Y. Tomizaki and K. Kajikawa and H. Mihara}, title = {Anomalous Reflection of Gold Applicable for a Practical Protein-detecting Chip Platform}, journal = { Mol. BioSyst.}, year = 2005, } @article{CTT100404918, author = {K. Usui and T. Ojima and K.-Y. Tomizaki and H. Mihara}, title = {A Designed Glycopeptide Array for Characterization of Sugar-Binding Proteins Toward a Glycopeptide Chip Technology}, journal = {NanoBiotechnology}, year = 2005, } @article{CTT100404906, author = {K.-Y. Tomizaki and J. Xu and H. Mihara}, title = {A Chromism-Based Assay (CHROBA) Technique for in situ Detection of Protein Kinase Activity}, journal = {Bioorg. Med. Chem. Lett.}, year = 2005, } @article{CTT100404908, author = {K.-Y. Tomizaki and H. Mihara}, title = {A Novel Fluorescence Sensing System Using Photochromism-Based Assay (P-CHROBA) Technique for Detection of Target Proteins}, journal = {J. Mater. Chem.}, year = 2005, } @article{CTT100404919, author = {H. Mihara and S. Matsumura and T. Takahashi}, title = {Construction and Control of Self-Assembly of Amyloid and Fibrous Peptides}, journal = {Bull. Chem. Soc. Jpn.}, year = 2005, } @article{CTT100404922, author = {K.-Y. Tomizaki and K. Usui and H. Mihara}, title = {Protein-Detecting Microarrays: Current Accomplishments and Requirements}, journal = {ChemBioChem}, year = 2005, } @article{CTT100528146, author = {K. Usui and T. Ojima and K.-Y. Tomizaki and H. Mihara}, title = {A Designed Glycopeptide Array for Characterization of Sugar-Binding Proteins Toward a Glycopeptide Chip Technology}, journal = {NanoBiotechnology}, year = 2005, } @article{CTT100712260, author = {Hiroshi Tsutsumi and Hiroshi Ikeda and Hisakazu Mihara and Akihiko Ueno}, title = {Enantioselective Ester Hydrolysis Catalyzed by β-Cyclodextrin Conjugated with β-Hairpin Peptides}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2004, } @article{CTT100540129, author = {H. Miyanishi and T. Takahashi and H. Mihara}, title = {De Novo Design of Peptides with L-α-Nucleobase Amino Acids and Their Binding Properties to the P22 boxB RNA and its Mutants}, journal = {Bioconjugate Chem.}, year = 2004, } @article{CTT100540130, author = {H. Kodama and S. Matsumura and T. Yamashita and H. Mihara}, title = {Construction of a protein array on amyloid-like fibrils using coassembly of designed peptides}, journal = {Chem. Commun.}, year = 2004, } @article{CTT100540131, author = {K. Usui and T. Ojima and M. Suzuki and M. Takahashi and K. Nokihara and H. Mihara}, title = {Designed Peptide Microarrays and Protein Characterization Using Fingerprint Patterns}, journal = {Peptide Science 2003}, year = 2004, } @article{CTT100540132, author = {T. Takahashi and K. Tada and H. Oshima and S. Matsumura and H. Mihara}, title = {Construction of the Artificial Peptides and RNA Targeting Amyloid}, journal = {Peptide Science 2003}, year = 2004, } @article{CTT100540133, author = {K. Usui and M. Takahashi and T. Ojima and M. Suzuki and K. Nokihara and E. Tamiya and H. Mihara}, title = {Peptide Microarrays Using Structure-Based Peptide Libraries for Protein Chips}, journal = {Peptides, Peptide Revolution: Genomics, Proteomics & Therapeutics}, year = 2004, } @article{CTT100540135, author = {K. Nokihara and T. Ohyama and K. Usui and K. Yoneyama and M. Takahashi and H. Mihara}, title = {Development of Peptide-chips Focusing on a High Throughput Protein-detection System}, journal = {Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries}, year = 2004, } @article{CTT100540124, author = {Y. Takahashi and H. Mihara}, title = {Construction of a chemically and conformationally self-replicating system of amyloid-like fibrils}, journal = {Bioorg. Med. Chem.}, year = 2004, } @article{CTT100540126, author = {K. Usui and T. Ojima and M. Takahashi and K. Nokihara and H. Mihara}, title = {Peptide Arrays with Designed Secondary Structure for Protein Characterization Using Fluorescent Fingerprint Patterns}, journal = {Biopolymers}, year = 2004, } @article{CTT100540127, author = {K. Usui and M. Takahashi and K. Nokihara and H. Mihara}, title = {Peptide Arrays with Designed alpha-Helical Structure for Characterization of Proteins from FRET Fingerprint Patterns}, journal = {Molecular Diversity}, year = 2004, } @article{CTT100388048, author = {Hideo Miyanishi and Tsuyoshi Takahashi and HISAKAZU MIHARA}, title = {De Novo Design of Peptides with L-alpha-Nucleobase Amino Acids and Their Binding Properties to the P22 boxB RNA and Its Mutants}, journal = {Bioconjugate Chemistry}, year = 2004, } @article{CTT100540128, author = {S. Matsumura and S. Uemura and H. Mihara}, title = {Fabrication of Nanofibers with Uniform Morphology by Self-Assembly of Designed Peptides}, journal = {Chem. Eur. J.}, year = 2004, } @article{CTT100540123, author = {H. Tsutsumi and H. Ikeda and H. Mihara and A. Ueno}, title = {Enantioselective ester hydrolysis catalyzed by beta-cyclodextrin conjugated with beta-hairpin peptides}, journal = {Bioorg. Med. Chem. Lett.}, year = 2004, } @article{CTT100537930, author = {S. Furukawa and H. Mihara and A. Ueno}, title = {Sensing Behavior of Fluorescent Cyclodextrin/Peptide Hybrids Bearing a Macrocyclic Metal Complex}, journal = {Macromol. Rapid Commun.}, year = 2003, } @article{CTT100537929, author = {H. Okamoto and T. Nakanishi and Y. Nagai and K.Takeda and I. Obataya and H. Mihara and H. Azehara and W. Mizutani}, title = {Theoretical Prediction and AFM Observations of the Protein Nanotube Consisting of Homo-L-Amino Acid Penta-Peptide Nanorings}, journal = {Jpn. J. Appl. Phys.}, year = 2003, } @article{CTT100539146, author = { K. Usui and M. Takahashi and A. Ueno and K. Nokihara and H. Mihara}, title = {Microarrays with alpha-Helical Peptides for Protein Detection using a FRET Technique}, journal = {Peptides 2002}, year = 2003, } @article{CTT100540122, author = {M. A. Hossain and H. Mihara and A. Ueno}, title = {Fluorescence Resonance Energy Transfer in a Novel Cyclodextrin-Peptide Conjugate for Detecting Steroid Molecules}, journal = {Bioorg. Med. Chem. Lett.}, year = 2003, } @article{CTT100539144, author = {H. Miyanishi and T. Takahashi and A. Ueno and H. Mihara}, title = {De Novo Design of α-Helical Peptide with Nucleobase Amino Acids that Specifically Recognize a Hairpin RNA}, journal = {Peptide Science 2002}, year = 2003, } @article{CTT100539143, author = {H. Mihara and M. Takahashi and K. Usui and T. Ojima and K. Nokihara}, title = {Structure-Designed Peptide Microarrays for Protein-Detection}, journal = {Peptide Science 2002}, year = 2003, } @article{CTT100539142, author = {H. Mihara and S. Matsumura and A. Ueno}, title = {Template-Directed Ligation Enhanced by Complementary Interaction using Nucleobase Amino Acids}, journal = {Peptides 2002}, year = 2003, } @article{CTT100539141, author = { I. Obataya and A. Ueno and H. Mihara}, title = {Design and Synthesis of Three-alpha-Helix Proteins that Bind Small Ligands in a Cavity}, journal = {Peptides 2002}, year = 2003, } @article{CTT100539140, author = {H. Miyanishi and T. Takahashi and A. Ueno and H. Mihara}, title = {De Novo Design of Peptides containing L-α-Nucleobase Amino Acids and their Recognition of Hairpin RNA}, journal = {Peptides 2002}, year = 2003, } @article{CTT100539139, author = {H. Mihara and M. Takahashi and K. Usui and T. Ojima and A. Ueno and K. Nokihara}, title = {Protein-Detection Systems using Structure-Based Peptide Libraries and Microarrays}, journal = {Peptides 2002}, year = 2003, } @article{CTT100539132, author = {S. Matsumura and T. Takahashi and A. Ueno and H. Mihara}, title = {Complementary nucleobase interaction enhances peptide-peptide recognition and self-replicating catalysis}, journal = {Chem. Eur. J.}, year = 2003, } @article{CTT100539131, author = {T. Yamashita and Y. Takahashi and T. Takahashi and H. Mihara}, title = {Inhibition of Peptide Amyloid Formation by Cationic Peptides with Homologous Sequences}, journal = {Bioorg. Med. Chem. Lett.}, year = 2003, } @article{CTT100539130, author = {M. A. Hossain and K. Takahashi and H. Mihara and A. Ueno}, title = {Novel Peptides Bearing Pyrene and Coumarin Units with or withoutβ-Cyclodextrin in Their Side Chains Exhibit Intramolecular Fluorescence Resonance Energy Transfer}, journal = {J. Am. Chem. Soc.}, year = 2003, } @article{CTT100539061, author = {M. Takahashi and K. Nokihara and H. Mihara}, title = {Construction of a Protein-Detection System Using a Loop Peptide Library with a Fluorescence Label}, journal = {Chemistry & Biology}, year = 2003, } @article{CTT100539145, author = {M. Tsuruzono and I. Obataya and A. Ueno and H. Mihara}, title = {Design and Peroxidase-like Activity of 3α-Helix Hemoproteins}, journal = {Peptide Science 2002}, year = 2002, } @article{CTT100537926, author = {T. Toyoda and H. Mihara and A. Ueno}, title = {Fluorescent Cyclodextrin/Peptide Hybrids with a Novel Guest-Responsive Chemosensor in the Peptide Side Chain}, journal = {Macromol. Rapid Commun.}, year = 2002, } @article{CTT100537927, author = {M. A. Hossain and K. Takahashi and H. Mihara and A. Ueno}, title = {Molecular-Responsive Fluorescent Sensors of a-Helix Peptides Bearing alpha-Cyclodextrin, Pyrene and Nitrobenzene Units in Their Side Chains}, journal = {J. Incl. Phenom. Macrocycl. Chem.}, year = 2002, } @article{CTT100537928, author = {A. Ueno and T. Shimizu and H. Mihara and K. Hamasaki and K. Pitchumani}, title = {Supramolecular Chemistry of Cyclodextrin-Peptides: Azobenzene-Tagged Prptide}, journal = {J. Inclusion Phenom. Macrocycl. Chem.}, year = 2002, } @article{CTT100539137, author = {Y. Takahashi and T. Yamashita and A. Ueno and H. Mihara}, title = {Complementary Assembly of Heterogenous Peptides into Amyloid Fibrils and Their Catalytic Function}, journal = {Peptide Science 2001}, year = 2002, } @article{CTT100539138, author = {K. Usui and M. Takahashi and A. Ueno and K. Nokihara and H. Mihara}, title = {Construction of a Protein-Detection System using Designed Peptides with Fluorescent Labels}, journal = {Peptide Science 2001}, year = 2002, } @article{CTT100450926, author = {T. Takahashi and K. Hamasaki and A. Ueno and H. Mihara}, title = {Construction of Peptides with Nucleobase Amino Acids: Design and Synthesis of the Nucleobase-Conjugated Peptides Derived from HIV-1 Rev and their Binding Properties to HIV-1 RRE RNA }, journal = {Bioorg. Med. Chem.}, year = 2001, } @article{CTT100450931, author = {馬場嘉信 and 三原久和 and 浜地格 and 杉本直己}, title = {テーラーメイド・バイオケミストリーの目指すもの}, journal = {化学}, year = 2001, } @article{CTT100450930, author = {I. Obataya1 and S. Sakamoto and A. Ueno and H. Mihara}, title = {Design and Synthesis of 3a-Helix Peptides Forming a Cavity for a Fluorescent Ligand}, journal = {Biopolymers}, year = 2001, } @article{CTT100450929, author = {M. Sakamoto and A. Ueno and H. Mihara}, title = {Multi-Peptide-Metalloporphyrin Assembly on a Dendrimer Template and Photoinduced Electron Transfer Based on the Dendrimer Structure}, journal = {Chem. Eur. J.}, year = 2001, } @article{CTT100450928, author = {I. Kumagai and T. Takahashi and K. Hamasaki and A. Ueno and H. Mihara}, title = {HIV Rev Peptides Conjugated with Peptide Nucleic Acids and Their Efficient Binding to RRE RNA}, journal = {Bioorg. Med. Chem. Lett.}, year = 2001, } @article{CTT100506674, author = {H. Mihara and Y. Takahashi}, title = {Self-Assembly of Polypeptides into Amyloid Fibrils with Structural Transitions}, journal = {Trans. Material Res. Soc. Jpn.}, year = 2001, } @article{CTT100506673, author = {M. A. Hossain and K. Hamasaki and K. Takahashi and H. Mihara and A. Ueno}, title = {Guest-Induced Diminishment in Fluorescence Quenching and Molecule Sensing Ability of A Novel Cyclodextrin-Peptide Conjugate}, journal = {J. Am. Chem. Soc.}, year = 2001, } @article{CTT100506672, author = {M. Sakamoto and T. Kamachi1 and I. Okura1 and A. Ueno and H. Mihara}, title = {Photoinduced Hydrogen Evolution with Peptide DendrimerミMulti-Zn(II)-Porphyrin, Viologen and Hydrogenase}, journal = {Biopolymers}, year = 2001, } @article{CTT100506678, author = {三原久和}, title = {ポリペプチドの立体構造転移とアミロイド繊維への自己組織化}, journal = {機能材料}, year = 2001, } @article{CTT100450925, author = {Y. Takahashi and A. Ueno and H. Mihara}, title = {Heterogeneous Assembly of Complementary Peptide Pairs into Amyloid Fibrils with Structural Transition from a-Helix to b-Sheet}, journal = {ChemBioChem}, year = 2001, } @article{CTT100450927, author = {G. Balasundaram and T. Takahashi and A. Ueno and H. Mihara}, title = {Construction of Peptide Conjugates with Peptide Nucleic Acids Containing an Anthracene Probe and Their Interactions with DNA}, journal = {Bioorg. Med. Chem.}, year = 2001, } @article{CTT100712261, author = {Hiroshi Tsutsumi and Keita Hamasaki and Hisakazu Mihara and Akihiko Ueno}, title = {Rate Enhancement and Enantioselectivity in Ester Hydrolysis Catalysed by Cyclodextrin-Peptide Hybrids}, journal = {Journal of the Chemical Society Perkin Transactions 2}, year = 2000, } @article{CTT100712262, author = {Hiroshi Tsutsumi and Keita Hamasaki and Hisakazu Mihara and Akihiko Ueno}, title = {Cyclodextrin-Peptide Hybrid as a Hydrolytic Catalyst Having Multiple Functional Groups}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2000, } @article{CTT100436799, author = {H. Tsutsumi and K. Hamasaki and H. Mihara and A. Ueno}, title = {Cyclodextrin-Peptide Hybrid as a Hydrolytic Catalyst Having Multiple Functional Groups}, journal = {Bioorg. Med. Chem. Lett.}, year = 2000, } @article{CTT100506677, author = {三原久和}, title = {ファージディスプレイ法と化学法を融合させた人工タンパク質の合成}, journal = {高分子}, year = 2000, } @article{CTT100506671, author = {I. Obataya and T. Kotaki and S. Sakamoto and A. Ueno and H. Mihara}, title = {Design, Synthesis and Peroxidase-like Activity of 3a-helix Proteins Covalently Bound to Heme}, journal = {Bioorg. Med. Chem. Lett.}, year = 2000, } @article{CTT100506646, author = {HISAKAZU MIHARA}, title = {Peptides Undergoing Secondary Structural Transition and Self-assembly into Amyloid Fibril Based on Structural Complementarity }, journal = {Peptide Science 1999}, year = 2000, } @article{CTT100506645, author = {M. A. Hossain and K. Hamasaki and H. Mihara and A. Ueno}, title = {Association and Guest-induced Dissociation of a Novel α-Helix Peptide Bearing Pyrene and γ-Cyclodextrin in the Side Chains }, journal = {Chem.Lett.}, year = 2000, } @article{CTT100506644, author = {M. A. Hossain and T. Kanai and S. Matsumura and K. Hamasaki and H. Mihara and A. Ueno}, title = {Association of α-Helix Peptides that have γ-Cyclodextrin in the Side Chain, and Induction of Dissociation of the Association Dimer by External Stimulant Molecules}, journal = {J. Chem. Soc., Perkin Trans. 2}, year = 2000, } @article{CTT100436807, author = {I. Obataya and S. Sakamoto and A. Ueno and H. Mihara}, title = {Design and synthesis of 3α-helix bundle peptide possessing a hydrophobic cavity}, journal = {Peptide Science 1999}, year = 2000, } @article{CTT100436806, author = {M. Takahashi and A. Ueno and H. Mihara}, title = {Recognition of porphyrin or protein using peptides derived from antibody CDR}, journal = {Peptide Science 1999}, year = 2000, } @article{CTT100436805, author = {T. Takahashi and I. Kumagai and K. Hamasaki and A. Ueno and H. Mihara}, title = {Design and Synthesis of Peptides Containing Nucleobase Amino Acids and their Interaction with RNA }, journal = {Peptide Science 1999}, year = 2000, } @article{CTT100436801, author = {I. Kumagai and T. Takahashi and K. Hamasaki and A. Ueno and H. Mihara}, title = {Construction of HIV Rev Peptides Containing Peptide Nucleic Acid that Bind HIV RRE IIB RNA }, journal = {Bioorg. Med. Chem. Lett.}, year = 2000, } @article{CTT100436800, author = {T. Takahashi and K. Hamasaki and I. Kumagai and A. Ueno and H. Mihara}, title = {Design of a Nucleobase-Conjugated Peptides that Recognizes HIV-1 RRE IIB RNA with High Affinity and Specificity }, journal = {Chem. Commun.}, year = 2000, } @article{CTT100436798, author = {S. Matsumura and S. Sakamoto and A. Ueno and H. Mihara}, title = {Construction of α-Helix Peptides with β-Cyclodextrin and Dansyl Units and Their Conformational and Molecular Sensing Properties}, journal = {Chem. Eur. J.}, year = 2000, } @article{CTT100436785, author = {K. Tomizaki and Y. Tsunekawa and H. Akisada and H. Mihara and N. Nishino}, title = {Design and Characterization of Flavoemzyme Models in the Course of Chemical Evolution of Four-α-Helix Bundle Polypeptides}, journal = {J. Chem. Soc., Perkin Trans. 2}, year = 2000, } @article{CTT100436784, author = {T. Toyoda and S. Matsumura and H. Mihara and A. Ueno}, title = {Guest-responsive Excimer Emission in an α-Helix Peptide Bearing γ-Cyclodextrin and Two Naphthalene Units}, journal = {Macromol. Rapid Commun.}, year = 2000, } @article{CTT100436783, author = {S. Matsumura and A. Ueno and H. Mihara}, title = {Peptides with Nucleobase Moieties as a Stabilizing Factor for a Two-Stranded α-Helix}, journal = {Chem.Commun.}, year = 2000, } @article{CTT100436782, author = {C. Matsumoto and K. Hamasaki and H. Mihara and A. Ueno}, title = {A High-Throughput Screening Utilizing Intramolecular Fluorescence Resonance Energy Transfer for the Discovery of the Molecules that Bind HIV-1 TAR RNA Specifically}, journal = {Bioorg. Med. Chem. Lett.}, year = 2000, } @article{CTT100436781, author = {H. Tsutsumi and K. Hamasaki and H. Mihara and A. Ueno}, title = {Rate Enhancement and Enantioselectivity in Ester Hydrolysis Catalysed by Cyclodextrin-Peptide Hybrids}, journal = {J. Chem. Soc., Perkin Trans. 2}, year = 2000, } @article{CTT100436780, author = {M. Sakamoto and A. Ueno and H. Mihara}, title = {Construction of α-Helical Peptide Dendrimers Conjugated with Multimetalloporphyrins:Photoinduced Electron Transfer on Dendrimer Architechture}, journal = {Chem. Commun.}, year = 2000, } @article{CTT100436779, author = {Y. Takahashi and T. Yamashita and A. Ueno and H. Mihara}, title = {Construction of Peptides that Undergo Structural Transition from α-Helix to β-Sheet and Amyloid Fibril Formation by the Introduction of N-Terminal Hydrophobic Amino Acids}, journal = {Tetrahedron}, year = 2000, } @article{CTT100436778, author = {Y. Takahashi and A. Ueno and H. Mihara}, title = {Mutational Analysis of Designed Peptides that Undergo Structural Transition from α Helix to β Sheet and Amyloid Fibril Formation}, journal = {Structure}, year = 2000, } @article{CTT100436777, author = {M. Takahashi and A. Ueno and H. Mihara}, title = {Peptide Design Based on an Antibody Complementarity-Determining Region (CDR): Construction of Porphyrin-Binding Peptides and Their Affinity Maturation by a Combinatorial Method}, journal = {Chem. Eur. J.}, year = 2000, } @article{CTT100436761, author = {H. Kuribayashi and T. Takahashi and K. Nagata and A. Ueno and H. Mihara}, title = {Construction of Two-Stranded α-Helix Peptides Based on Influenza Virus M1 Protein Selectively Bound to RNA}, journal = {Bioorg. Med. Chem. Lett.}, year = 2000, } @article{CTT100436760, author = {松村幸子 and 三原久和}, title = {タンパク質合成における化学と分子生物学の融合}, journal = {化学}, year = 2000, } @article{CTT100421918, author = {高橋勇太 and 三原久和}, title = {ペプチドの立体構造転移とアミロイド形成 }, journal = {化学と生物}, year = 1999, } @article{CTT100421917, author = {S. Sakamoto and I. Obataya and A. Ueno and H. Mihara}, title = {Effects of amino acids substitution of hydrophobic residues on haem-binding properties of designed two-α-helix peptides}, journal = {J. Chem. Soc., Perkin Trans. 2}, year = 1999, } @article{CTT100421916, author = {M. Takahashi and Y. Ohgitani and A. Ueno and H. Mihara}, title = {Design of Peptides Derived form Anti-IgE Antibody for Allergic Treatment }, journal = {Bioorg. Med. Chem. Lett.}, year = 1999, } @article{CTT100421915, author = {I. Obataya and S. Sakamoto and A. Ueno and H. Mihara}, title = {Nanoparticle Formation of Self-Assembling Two-α- Helix Peptide Induced by Heme-Binding }, journal = {Protein and Peptide Letters}, year = 1999, } @article{CTT100421914, author = {S. Sakamoto and I. Obataya and A. Ueno and H. Mihara}, title = {Regulation of alpha/beta-Folding of a Designed Peptide by Haem Binding}, journal = {Chem.Commun.}, year = 1999, } @article{CTT100421851, author = {Y. Takahashi and A. Ueno and H. Mihara}, title = {Optimization of Hydrophobic Domains in Peptides that Undergo Transformation from α-Helix to β-Fibril}, journal = {Bioorg. Med. Chem.}, year = 1999, } @article{CTT100421930, author = {S. Sakamoto and A. Ueno and H. Mihara}, title = {Design, Synthesis and Characterization of Heme-Conjugated Two-alpha-Helix Peptides}, journal = {Peptides Science-Present and Future}, year = 1999, } @article{CTT100506577, author = {Y. Takahashi and A. Ueno and H. Mihara}, title = {Conformational Self Replication of Peptide: Conversion from alpha-Helix to beta-Fibril of Designed Coiled-Coil Peptide }, journal = {Peptides 1998}, year = 1999, } @article{CTT100506578, author = {S. Matsumura and S. Sakamoto and A. Ueno and H. Mihara}, title = {Construction of Cyclodextrin-Peptide Conjugates and Their Molecular Sensing Properties   }, journal = {Peptides Science-Present and Future}, year = 1999, } @article{CTT100506579, author = {S. Sakamoto and A. Ueno and H. Mihara}, title = {De Novo Design, Synthesis and Characterization of Heme-Conjugated Two-alpha-Helix Peptides }, journal = {Peptide Science 1998}, year = 1999, } @article{CTT100421929, author = {Y. Takahashi and A. Ueno and H. Mihara}, title = {Self-catalytic Conversion of Peptides from alpha-Helix to beta-Structural Amyloid }, journal = {Peptides Science-Present and Future }, year = 1999, } @article{CTT100421928, author = {I. Obataya and S. Sakamoto and A. Ueno and H. Mihara}, title = {Peptide Nanosphere: Formation of Nanoparticles of Two-alpha-Helix Peptides Induced by Heme-Binding}, journal = {Peptides 1998}, year = 1999, } @article{CTT100421927, author = {S. Sakamoto and A. Ueno and H. Mihara}, title = {Molecular-Assembly of Heme-Binding Two-alpha-Helix Peptide}, journal = {Peptides 1998}, year = 1999, } @article{CTT100436804, author = {T. Haruyama and S. Sakamoto and H. Mihara and M. Aizawa}, title = {Electron Transfer of Flavin-pendant α-Helical Peptides Self-Assembled on an Electrode}, journal = {Electrochemistry}, year = 1999, } @article{CTT100506580, author = {Y. Takahashi and A. Ueno and H. Mihara}, title = {An alpha-to-beta Structural Transition and Amyloidgenesis of Peptides: Effects of Amino Acid Substitution on Self-replicating Organization }, journal = {Peptide Science 1998}, year = 1999, } @article{CTT100421932, author = {M. Takahashi and A. Ueno and T.Uda and H. Mihara}, title = {Construction of Porphyrin-Binding Peptides Mimicking Anti Heme Monoclonal Antibody}, journal = {Peptides Science-Present and Future}, year = 1999, } @article{CTT100421931, author = {I. Obataya and S. Sakamoto and A. Ueno and H. Mihara}, title = {Self-Assembly of Heme-Conjugated Two-alpha-Helix Peptides}, journal = {Peptides Science-Present and Future}, year = 1999, } @article{CTT100506581, author = {H. Kuribayashi and T. Takahashi and A. Ueno and H. Mihara}, title = {Interaction of Basic Peptides Derived from Influenza Virus M1 Protein with DNA/RNA }, journal = {Peptide Science 1998}, year = 1999, } @article{CTT100421848, author = {S. Sakamoto and A. Ueno and H. Mihara}, title = {Annealing of Two-a-Helix Structure by Metal Ion Binding Regulated with Trifluoroethanol}, journal = {Chem. Lett.}, year = 1998, } @article{CTT100416127, author = {M. Takahashi and A. Ueno and T. Uda and H. Mihara}, title = {Design of Novel Porphyrin-Binding Peptides Based on Antibody CDR}, journal = {Bioorg. Med. Chem. Lett.}, year = 1998, } @article{CTT100416128, author = {H. Mihara and Y. Takahashi and A. Ueno}, title = {Design of Peptides Undergoing Self-Catalytic α-to-β Transition and Amyloidogenesis}, journal = {Biopolymers}, year = 1998, } @article{CTT100421845, author = {T. Niidome and H. Mihara and A. Oka and T. Hayashi and T. Saiki and K. Yoshida and H. Aoyagi}, title = {Structure and Property of Model Peptides of Proline/Arginine-rich Region in Bactenesin 5}, journal = {J. Pept. Res.}, year = 1998, } @article{CTT100421846, author = {N. Ohmori and T. Niidome and T. Hatakeyama and H. Mihara and H. Aoyagi}, title = {Interaction of a-Helical Peptides with Phospholipid Membrane: Effects of Chain Length and Hydrophobicity of Peptides}, journal = {J. Pept. Res.}, year = 1998, } @article{CTT100421926, author = {H. Aoyagi and M. Kimura and T. Niidome and T. Hatakeyama and H. Mihara}, title = {Interaction with Membranes of Peptides Related to the Fusogenic Region of PH-30a, a Sperm-Egg Fusion Protein}, journal = { Peptides: Frontiers of Peptide Science}, year = 1998, } @article{CTT100421925, author = {Y. Takahashi and A. Ueno and H. Mihara}, title = {alpha to beta Transition of Peptides Caused by Hydrophobic Defects}, journal = {Peptides: Frontiers of Peptide Science}, year = 1998, } @article{CTT100421924, author = {T. Takahashi and A. Ueno and H. Mihara}, title = {Combination of a-Helix Peptides with Intercalator Anthracene for Reporting Peptide-DNA Interactions}, journal = {Peptides: Frontiers of Peptide Science}, year = 1998, } @article{CTT100421923, author = {H. Kuribayashi and T. Takahashi and K. Watanabe and K. Nagata and A. Ueno and H. Mihara}, title = {Interaction of Peptides from Influenza Virus Matrix Protein with Nucleic Acids}, journal = {Nucleic Acids Symposium Series}, year = 1998, } @article{CTT100421850, author = {S. Sakamoto and A. Ueno and H. Mihara}, title = {Design and Synthesis of Haem-Binding Peptides. Relationship between Haem-Binding Properties and Catalytic Activities}, journal = {J. Chem. Soc., Perkin Trans. 2}, year = 1998, } @article{CTT100421849, author = {Y. Takahashi and A. Ueno and H. Mihara}, title = {Design of a Peptide Undergoing alpha-beta Structural Transition and Amyloid Fibrillogenesis by the Introduction of Hydrophobic Defect}, journal = {Chem. Eur. J.}, year = 1998, } @article{CTT100421847, author = {S. Sakamoto and A. Ueno and H. Mihara}, title = {Molecular-Assembly of Two-a-Helix Peptide Induced by Haem-Binding}, journal = {J. Chem. Soc., Chem. Commun.}, year = 1998, } @article{CTT100416126, author = {S. Sakamoto and S. Sakurai and A. Ueno and H. Mihara}, title = {Haem Binding and Catalytic Activity of Two-α-Helix Peptide Annealed by Trifluoroethanol}, journal = {J. Chem. Soc. , Chem. Commun.}, year = 1997, } @article{CTT100421922, author = {坂本清志 and 三原久和}, title = {ポリペプチドワールド}, journal = {化学と工業}, year = 1997, } @article{CTT100416125, author = {H. Mihara and Y. Takahashi}, title = {Engineering Peptides and Proteins that Undergo α-to-β Transitions}, journal = {Curr. Opin. Struct. Biol.}, year = 1997, } @article{CTT100416123, author = {HISAKAZU MIHARA}, title = {Chiral Assembly of Porphyrins Regulated by Amphiphilic α-Helix Peptides}, journal = {Chem.Lett.}, year = 1996, } @article{CTT100416124, author = {三原久和 and 青柳東彦 and 西野憲和}, title = {人工膜タンパク質を指向した膜埋設型ペプチド超構造体の構築}, journal = {高分子論文集}, year = 1995, } @article{CTT100416119, author = {HISAKAZU MIHARA}, title = {A pair of Pyrene Groups as a Conformational Probe for Designed Two α-Helix Polypeptides}, journal = {J. Chem. Soc. , Perkin Trans. 2}, year = 1995, } @article{CTT100416121, author = {HISAKAZU MIHARA}, title = {A Pair of Pyrene Groups as a Conformational Probe for Designed Four-α-Helix Bundle Polypoptides}, journal = {J.Chem.Soc,Perkin Trans.2}, year = 1995, } @article{CTT100416122, author = {HISAKAZU MIHARA}, title = {Efficient Systhesis of Cyclic Peptide Mixtures by Solid Phase Synthesis and Cydization Cleavage with Oxime Resin}, journal = {Tetrahedron Lett.}, year = 1995, } @article{CTT100416120, author = {三原久和 and 西野憲和}, title = {オキシム樹脂固相合成およびセグメント縮合法によるペプチド・タンパク質の合成}, journal = {有機合成化学協会誌}, year = 1994, } @article{CTT100416118, author = {N. Nishino and M. Xu and H. Mihara and T. Fujimoto}, title = {Tryptic Condensation Combined with Peptide Segment Synthesis Condensation Strategy for the Efficient Synthesis of Human Growth Hormone Releasing Factor (1-29) Amide}, journal = {J. Chem. Soc. , Chem. Commun.}, year = 1992, } @article{CTT100416116, author = {E. T. Kaiser and H. Mihara and G. A. Laforet and J. W. Kelly and L. Walters and M. A. Findeis}, title = {Peptide and Protein Synthesis by Segment Synthesis-Condensation}, journal = {Science}, year = 1989, } @article{CTT100416117, author = {H. Mihara and E. T. Kaiser}, title = {A chemically Synthesized Antennapedia Homeo Domain Binds to a Specific DNA Sequence}, journal = {Science}, year = 1988, } @inproceedings{CTT100916848, author = {Masahiro Hashimoto and Takayuki Miki and Hiroki Takahashi and Sae Nakayama and Tadaomi Furuta and Hisakazu Mihara}, title = {Intracellular bottom-up reconstruction of liquid droplet by fusion of YK amphiphilic peptide tag}, booktitle = {}, year = 2023, } @inproceedings{CTT100879492, author = {三木 卓幸 and 高橋 広樹 and 橋本 匡浩 and 梶原 圭悟 and 中山 彩恵 and 三原 久和}, title = {細胞内で自己集合するペプチドタグ開発2:蛋白質高次構造体の設計と構築}, booktitle = {}, year = 2022, } @inproceedings{CTT100879493, author = {橋本 匡浩 and 三木 卓幸 and 中井 太一 and 丹羽 達也 and 三原 久和}, title = {細胞内で自己集合するペプチドタグ開発1:クラスター形成を伴う蛋白質間相互作用解析}, booktitle = {}, year = 2022, } @inproceedings{CTT100879491, author = {Takayuki Miki and Masahiro Hashimoto and Taich Nakai and Keigo Kajiwara and Hisakazu Mihara}, title = {Intracellular reconstitution and analysis of protein complexes by Yn self-assembling peptide tag}, booktitle = {}, year = 2021, } @inproceedings{CTT100879498, author = {Hiroki takahashi and Takayuki Miki and Taichi Nakai and Masahiro Hashimoto and Hisakazu Mihara}, title = {DEVELOPMENT OF AMPHIPHILIC YK PEPTIDE TAGS FOR BOTTOM-UP CONSTRUCTION OF LIQUID-LIQUID PHASE SEPARATION}, booktitle = {}, year = 2021, } @inproceedings{CTT100879494, author = {三木 卓幸 and 橋本 匡浩 and 高橋 広樹 and 梶原 圭悟 and 中山 彩恵 and 中井 太一 and 三原 久和}, title = {両親媒性ペプチドによる細胞内での蛋白質高次構造体の形成}, booktitle = {}, year = 2021, } @inproceedings{CTT100879495, author = {橋本 匡浩 and 三木 卓幸 and 中井 太一 and 三原 久和}, title = {Yn設計ペプチドによる細胞内でのクラスター形成を伴う蛋白質間相互作用解析}, booktitle = {}, year = 2021, } @inproceedings{CTT100879496, author = {筧 翔太 and 瀬古 健太 and 三木 卓幸 and 三原 久和}, title = {Hisタグ融合hDM2を標的としたNi(II)錯体修飾ファージディスプレイ法の確立}, booktitle = {}, year = 2021, } @inproceedings{CTT100643338, author = {土谷正樹 and 澤田敏樹 and 高橋 剛 and 三原久和}, title = {機能性バイオマテリアル構築を目的としたカルシウムイオン応答性自己組織化ペプチドナノファイバーの構築}, booktitle = {}, year = 2011, } @inproceedings{CTT100716586, author = {古木隆生 and 清水天平 and S. Charkrabortee and 畑中理恵 and 高橋剛 and 黄川田隆洋 and 奥田隆 and 三原久和 and A. Tunnacliffe and 櫻井実}, title = {グループ3LEAタンパク質の22-merモデルペプチドが示すタンパク質凝集抑制効果}, booktitle = {低温生物工学会誌}, year = 2011, } @inproceedings{CTT100599368, author = {Takao Furuki and Tempei Shimizu and Tsuyoshi Takahashi and Hisakazu Mihara and Takahiro Kikawada and Takashi Okuda and Minoru Sakurai}, title = {Model Study of the Desiccation-induced Vitrification of Group-3 Late Embrogenesis Abundant Proteins}, booktitle = {Cryobiol. Cryotech.}, year = 2010, } @inproceedings{CTT100591282, author = {Syahir Amir and 梶川浩太郎 and 三原久和}, title = {金属・絶縁体・金属(MIM)構造をセンシング基盤に用いた分子間相互作用の検出}, booktitle = {}, year = 2009, } @inproceedings{CTT100907798, author = {臼井健二 and 三重正和 and 三原久和 and 小畠英理}, title = {アミロイドβペプチドの局在と凝集の解析が可能な発光・蛍光タンパク質の構築}, booktitle = {}, year = 2009, } @inproceedings{CTT100552430, author = {Ryuichi Uozumi and Tsuyoshi Takahashi and HISAKAZU MIHARA}, title = {Design of beta-Hairpin Peptides Having Nucleobase Amino Acids (NBAs) and}, booktitle = {Peptide Science 2007 (S. Aimoto & S. Ono, Eds.)}, year = 2008, } @inproceedings{CTT100907830, author = {柿山喬 and 富崎欣也 and 臼井健二 and 三重正和 and 小畠英理 and 三原久和}, title = {細胞アッセイのための光切断型ペプチドアレイの構築}, booktitle = {}, year = 2007, } @inproceedings{CTT100571043, author = {S. Watanabe and K. Kajikawa and H. Mihara}, title = {Interactions Between Peptides Containing Nucleobase Amino Acids and T7 Phages Displaying S. cerevisiae Proteins}, booktitle = {Peptide Science}, year = 2007, } @inproceedings{CTT100562000, author = {T. Shimizu and Y. Kanamori and T. Furuki and T. Okuda and T. Kikawada and T. Takahashi and H. Mihara and M. Sakurai}, title = {Model study of the desiccation-induced structural transformations of Group-3 Late Embryogenesis Abundant (G3LEA) proteins}, booktitle = {Cryobiol. Cryotech.}, year = 2007, } @inproceedings{CTT100552122, author = {Tsuyoshi Takahashi and K. Ohta and HISAKAZU MIHARA}, title = {Construction of Green Fluorescent Protein (GFP) Variants That Interact with Amyloid β-Peptide.}, booktitle = {Peptide Science 2006}, year = 2006, } @misc{CTT100785177, author = {Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Self-Assembly of Designed Peptides and Their Nanomaterials Applications}, year = 2013, } @misc{CTT100712226, author = {Hiroshi Tsutsumi and Hisakazu Mihara}, title = {Soft Materials Based on Designed Self-Assembling Peptides: from Design to Application}, year = 2013, } @misc{CTT100598271, author = {高橋 剛 and 三原久和}, title = {アミロイドタンパク質をはかる}, year = 2009, } @misc{CTT100552150, author = {高橋 剛 and 三原久和}, title = {生体反応を司るらせん・たんぱく質のらせん構造}, year = 2007, } @misc{CTT100552149, author = {富崎欣也 and 三原久和}, title = {タンパク質検出チップ}, year = 2007, } @misc{CTT100552148, author = {三原久和}, title = {タンパク質分析用バイオチップ}, year = 2007, } @misc{CTT100552151, author = {高橋 剛 and 松村幸子 and 三原久和}, title = {アミロイドβペプチド(Aβ)を標的とした人工タンパク質・ペプチドの設計とAβ集}, year = 2007, } @misc{CTT100528161, author = {三原久和}, title = {ポストゲノム時代はケミカルライブラリーが活躍する}, year = 2006, } @misc{CTT100404923, author = {三原久和}, title = {図解高分子新素材のすべて, ペプチド工学}, year = 2005, } @misc{CTT100404926, author = {富崎欣也 and 三原久和}, title = {設計ペプチドを用いた次世代タンパク質検出システム}, year = 2005, } @misc{CTT100540134, author = {上村 忍 and 松村幸子 and 菊地 円 and 三原久和}, title = {βシートペプチドによるナノスケールファイバーの構築}, year = 2004, } @misc{CTT100540136, author = {軒原清史 and 大山貴史 and 臼井健二 and 米村耕一 and 富崎欣也 and 三原久和}, title = {ペプチドアレイを用いたプロテインチップの実用化を目指した研究}, year = 2004, } @misc{CTT100540137, author = {高橋 剛 and 三原久和}, title = {新しいタンパク質をデノボ創成する}, year = 2004, } @misc{CTT100539136, author = {臼井健二 and 三原久和}, title = {ペプチドマイクロアレイ:ペプチドライブラリを用いた新規プロテインチップの創成}, year = 2003, } @misc{CTT100539135, author = {三原久和}, title = {ペプチドアミロイド繊維状構造体の構築と制御}, year = 2003, } @misc{CTT100539134, author = {臼井健二 and 三原久和}, title = {プロテインチップ}, year = 2003, } @misc{CTT100539133, author = {三原久和}, title = {テーラーメイドバイオテクノロジー}, year = 2003, } @misc{CTT100596245, author = {HISAKAZU MIHARA}, title = {蛍光性エンケファリンアナローグの合成と性質:レセプター 結合親和性とリン脂質との相互作用に関する研究}, year = 1986, } @misc{CTT100609874, author = {梶川浩太郎 and アミル シャビル ビン アミル アム and 三原久和}, title = {バイオセンシング用基板}, howpublished = {公開特許}, year = 2010, month = {}, note = {特願2008-259655(2008/10/06), 特開2010-091321(2010/04/22)} } @misc{CTT100587187, author = {梶川浩太郎 and 三原久和 and AMIR SYAHIR BIN AMIR}, title = {センサ基板及びバイオセンサ}, howpublished = {公開特許}, year = 2009, month = {}, note = {特願2007-223950(2007/08/30), 特開2009-058263(2009/03/19)} } @misc{CTT100573087, author = {三原久和 and 富崎 欣也}, title = {分子メモリ及び分子論理回路}, howpublished = {公開特許}, year = 2008, month = {}, note = {特願2006-207019(2006/07/28), 特開2008-031105(2008/02/14)} } @phdthesis{CTT100596245, author = {HISAKAZU MIHARA}, title = {蛍光性エンケファリンアナローグの合成と性質:レセプター 結合親和性とリン脂質との相互作用に関する研究}, school = {九州大学}, year = 1986, }