@book{CTT100542295, author = {中川大 and 永井和夫}, title = {茶の効能と応用開発・破骨細胞の機能を調節する緑茶成分EGCG.}, publisher = {シーエムシー出版}, year = 2006, } @book{CTT100409371, author = {石川智久 and 櫻井亜季 and 大西裕子 and 中川大}, title = {バイオインダストリー・癌の薬剤耐性機構解明から薬物トランスポーター遺伝子多型の臨床診断へ.}, publisher = {シーエムシー出版}, year = 2005, } @article{CTT100809968, author = {Hiroshi Nakagawa and Yasumasa Joti and Akio Kitao and Osamu Yamamuro and Mikio Kataoka}, title = {Universality and Structural Implications of the Boson Peak in Proteins}, journal = {Biophysical Journal}, year = 2019, } @article{CTT100525517, author = {Hiroshi Nakagawa and Hasumi, K. and Takami, M. and Aida-Hyugaji, S. and Woo, J. T. and Kazuo Nagai and Toshihisa Ishikawa and Masaaki Wachi}, title = {Identification of two biologically crucial hydroxyl groups of (-)-epigallocatechin gallate in osteoclast culture}, journal = {Biochem. Pharmacol.}, year = 2007, } @article{CTT100525360, author = {Tamura, A. and Wakabayashi, K. and Onishi, Y. and Nakagawa, H. and Tsuji, M. and Matsuda, Y. and Ishikawa, T.}, title = {Genetic Polymorphisms of Human ABC Transporter ABCG2: Development of the Standard Method for Functional Validation of SNPs by using the Flp Recombinase System.}, journal = {J. Exp. Ther. Oncol.}, year = 2006, } @article{CTT100525361, author = {田村藍 and 大西裕子 and 渡邉正人 and 齊藤光 and 中川大 and 蒲池利章 and 大倉一郎 and 石川智久.}, title = {ヒトABCトランスポーターABCG2の遺伝子多型とポルフィリン症のリスク.}, journal = {Porphyrins}, year = 2006, } @article{CTT100409375, author = {Ishikawa, T. and Ikegami, Y. and Sano, K. and Nakagawa, H. and Sawada, S.}, title = {Transport mechanism-based drug molecular design: novel camptothecin analogues to circumvent ABCG2-associated drug resistance of human tumor cells.}, journal = {Curr. Pharm. Des.}, year = 2006, } @article{CTT100409376, author = {Nakagawa, H. and Saito, H. and Ikegami, Y. and Aida-Hyugaji, S. and Sawada, S. and Ishikawa, T.}, title = {Molecular Modeling of New Camptothecin Analogues to Circumvent ABCG2-mediated Drug Resistance in Cancer.}, journal = {Cancer Lett.}, year = 2006, } @article{CTT100525357, author = {Saito, H. and Hirano, H. and Nakagawa, H. and Fukami, T. and Oosumi, K. and Murakami, K. and Kimura, H. and Kouchi, T. and Konomi, M. and Tao, E. and Tsujikawa, N. and Tarui, S. and Nagakura, M. and Osumi, M. and Ishikawa, T.}, title = {A New Strategy of High-Speed Screening and Quantitative SAR Analysis To Evaluate Human ABC Transporter ABCG2-Drug Interactions.}, journal = {J. Pharmacol. Exp. Ther.}, year = 2006, } @article{CTT100525359, author = {Tamura, A. and Watanabe, M. and Saito, H. and Nakagawa, H. and Kamachi, T. and Okura, I. and Ishikawa, T.}, title = {Functional Validation of The Genetic Polymorphisms of Human ABC Transporter ABCG2: Identification of Alleles That Are Defective in Porphyrin Transport.}, journal = {Mol. Pharmacol.}, year = 2006, } @article{CTT100525358, author = {Hirano, H. and Kurata, A. and Onishi, Y. and Sakurai, A. and Saito, H. and Nakagawa, H. and Nagakura, M. and Tarui, S. and Kanamori, Y. and Kitajima, M. and Ishikawa, Y.}, title = {High-Speed Screening and QSAR Analysis of Human ATP-Binding Cassette Transporter ABCB11 (Bile Salt Export Pump) To Predict Drug-induced Intrahepatic Cholestasis.}, journal = {Mol. Pharmaceutics}, year = 2006, } @article{CTT100409374, author = {Wakabayashi, K. and Nakagawa, H. and Adachi, T. and Kii, I. and Kobatake, E. and Kudo, A. and Ishikawa, T.}, title = {Cysteine-603 is a critical amino acid forhomodimer formation of human ATP-binding cassette transporter ABCG2: a new approach using the flp recombinase system.}, journal = {J. Exp. Ther. Oncol.}, year = 2006, } @article{CTT100525362, author = {Shirasaka Y and Onishi Y and Sakurai A and Nakagawa H and Ishikawa T and Yamashita S.}, title = {Evaluation of Human P-Glycoprotein (MDR1/ABCB1) ATPase Activity Assay Method by Comparing with in Vitro Transport Measurements: Michaelis-Menten Kinetic Analysis to Estimate the Affinity of P-Glycoprotein to Drugs.}, journal = {Biol. Pharm. Bull.}, year = 2006, } @article{CTT100409372, author = {Takahashi, T. and Nakai, K. and Doi, T. and Yasunaga, M. and Nakagawa, H. and Ishikawa, T.}, title = {Synthesis and Evaluation of 3D Templates Based on a Taxane Skeleton to Circumvent P-glycoprotein-associated Multidrug Resistance of Cancer.}, journal = {Bioorg. Med. Chem. Lett.}, year = 2005, } @article{CTT100409373, author = {Ishikawa, T. and Tamura, A. and Saito, H. and Wakabayashi, K. and Nakagawa, H.}, title = {Pharmacogenomics of the Human ABC Transporter ABCG2: From Functional Evaluation to Drug Molecular Design.}, journal = {Naturwissenschaften}, year = 2005, } @article{CTT100501308, author = {HIROSHI NAKAGAWA}, title = {Inhibitory effects of mevastatin and a geranylgeranyl transferase I inhibitor (GGTI-2166) on mononuclear osteoclast formation induced by receptor activator of NFkappaB ligand (RANKL) or tumor necrosis factor-alpha (TNF-alpha).}, journal = {Biochem Pharmacol.}, year = 2005, } @article{CTT100501858, author = {Nakagawa, H. and Hasumi, K. and Woo, J.-T. and Nagai, K. and Wachi, M.}, title = {Generation of hydrogen peroxide primarily contributes to the induction of Fe(II)-dependent apoptosis in Jurkat cells by (-)-epigallocatechin gallate}, journal = {Carcinogenesis}, year = 2004, } @article{CTT100500048, author = {HIROSHI NAKAGAWA}, title = {Generation of hydrogen peroxide primarily contributes to the induction of Fe(II)-dependent apoptosis in Jurkat cells by (-)-epigallocatechin gallate.}, journal = {Carcinogenesis}, year = 2004, } @article{CTT100500046, author = {HIROSHI NAKAGAWA}, title = {Quercetin suppresses bone resorption by inhibiting differentiation and activation of osteoclasts.}, journal = {Biological Pharm. Bull.}, year = 2004, } @article{CTT100500047, author = {HIROSHI NAKAGAWA}, title = {Destruxins, cyclodepsipeptides, block the formation of actin rings, and prominent clear zones and ruffled borders in osteoclasts.}, journal = {Bone}, year = 2003, } @article{CTT100500049, author = {HIROSHI NAKAGAWA}, title = {Fenton reaction is primarily involved in a mechanism of (-)-epigallocatechin-3-gallate to induce osteoclastic cell death.}, journal = {Biochem. Biophys. Res. Commun.}, year = 2002, } @misc{CTT100596476, author = {HIROSHI NAKAGAWA}, title = {破骨細胞による骨吸収を抑制する低分子生理活性物質デストラキシン及びカテキンの骨吸収抑制機構に関する研究}, year = 2004, } @misc{CTT100573091, author = {石川智久 and 中川大 and 渡邊 正人 and 齊藤 光}, title = {ABCタンパク質が輸送する基質のスクリーニング方法、及びABCタンパク質の輸送活性の測定法}, howpublished = {公開特許}, year = 2007, month = {}, note = {特願2005-353801(2005/12/07), 特開2007-151493(2007/06/21)} } @phdthesis{CTT100596476, author = {HIROSHI NAKAGAWA}, title = {破骨細胞による骨吸収を抑制する低分子生理活性物質デストラキシン及びカテキンの骨吸収抑制機構に関する研究}, school = {東京工業大学}, year = 2004, }