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中川大 研究業績一覧 (23件)
- 2024
- 2023
- 2022
- 2021
- 2020
- 全件表示
論文
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Hiroshi Nakagawa,
Yasumasa Joti,
Akio Kitao,
Osamu Yamamuro,
Mikio Kataoka.
Universality and Structural Implications of the Boson Peak in Proteins,
Biophysical Journal,
117,
2,
229-238,
July 2019.
公式リンク
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Hiroshi Nakagawa,
Hasumi, K.,
Takami, M.,
Aida-Hyugaji, S.,
Woo, J. T.,
Kazuo Nagai,
Toshihisa Ishikawa,
Masaaki Wachi.
Identification of two biologically crucial hydroxyl groups of (-)-epigallocatechin gallate in osteoclast culture,
Biochem. Pharmacol.,
Vol. 73,
No. 1,
pp. 34-43,
Jan. 2007.
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Tamura, A.,
Wakabayashi, K.,
Onishi, Y.,
Nakagawa, H.,
Tsuji, M.,
Matsuda, Y.,
Ishikawa, T..
Genetic Polymorphisms of Human ABC Transporter ABCG2: Development of the Standard Method for Functional Validation of SNPs by using the Flp Recombinase System.,
J. Exp. Ther. Oncol.,
Vol. 6,
pp. 1-11,
2006.
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田村藍,
大西裕子,
渡邉正人,
齊藤光,
中川大,
蒲池利章,
大倉一郎,
石川智久..
ヒトABCトランスポーターABCG2の遺伝子多型とポルフィリン症のリスク.,
Porphyrins,
Vol. 15,
pp. 21-22,
2006.
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Ishikawa, T.,
Ikegami, Y.,
Sano, K.,
Nakagawa, H.,
Sawada, S..
Transport mechanism-based drug molecular design: novel camptothecin analogues to circumvent ABCG2-associated drug resistance of human tumor cells.,
Curr. Pharm. Des.,
Vol. 12,
pp. 313-325,
2006.
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Nakagawa, H.,
Saito, H.,
Ikegami, Y.,
Aida-Hyugaji, S.,
Sawada, S.,
Ishikawa, T..
Molecular Modeling of New Camptothecin Analogues to Circumvent ABCG2-mediated Drug Resistance in Cancer.,
Cancer Lett.,
Vol. 234,
pp. 81-89,
2006.
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Saito, H.,
Hirano, H.,
Nakagawa, H.,
Fukami, T.,
Oosumi, K.,
Murakami, K.,
Kimura, H.,
Kouchi, T.,
Konomi, M.,
Tao, E.,
Tsujikawa, N.,
Tarui, S.,
Nagakura, M.,
Osumi, M.,
Ishikawa, T..
A New Strategy of High-Speed Screening and Quantitative SAR Analysis To Evaluate Human ABC Transporter ABCG2-Drug Interactions.,
J. Pharmacol. Exp. Ther.,
Vol. 317,
pp. 1114-1124,
2006.
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Tamura, A.,
Watanabe, M.,
Saito, H.,
Nakagawa, H.,
Kamachi, T.,
Okura, I.,
Ishikawa, T..
Functional Validation of The Genetic Polymorphisms of Human ABC Transporter ABCG2: Identification of Alleles That Are Defective in Porphyrin Transport.,
Mol. Pharmacol.,
Vol. 70,
pp. 287-296,
2006.
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Hirano, H.,
Kurata, A.,
Onishi, Y.,
Sakurai, A.,
Saito, H.,
Nakagawa, H.,
Nagakura, M.,
Tarui, S.,
Kanamori, Y.,
Kitajima, M.,
Ishikawa, Y..
High-Speed Screening and QSAR Analysis of Human ATP-Binding Cassette Transporter ABCB11 (Bile Salt Export Pump) To Predict Drug-induced Intrahepatic Cholestasis.,
Mol. Pharmaceutics,
Vol. 3,
pp. 252-265,
2006.
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Wakabayashi, K.,
Nakagawa, H.,
Adachi, T.,
Kii, I.,
Kobatake, E.,
Kudo, A.,
Ishikawa, T..
Cysteine-603 is a critical amino acid forhomodimer formation of human ATP-binding cassette transporter ABCG2: a new approach using the flp recombinase system.,
J. Exp. Ther. Oncol.,
Vol. 5,
pp. 205-222,
2006.
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Shirasaka Y,
Onishi Y,
Sakurai A,
Nakagawa H,
Ishikawa T,
Yamashita S..
Evaluation of Human P-Glycoprotein (MDR1/ABCB1) ATPase Activity Assay Method by Comparing with in Vitro Transport Measurements: Michaelis-Menten Kinetic Analysis to Estimate the Affinity of P-Glycoprotein to Drugs.,
Biol. Pharm. Bull.,
Vol. 29,
pp. 2465-2471,
2006.
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Takahashi, T.,
Nakai, K.,
Doi, T.,
Yasunaga, M.,
Nakagawa, H.,
Ishikawa, T..
Synthesis and Evaluation of 3D Templates Based on a Taxane Skeleton to Circumvent P-glycoprotein-associated Multidrug Resistance of Cancer.,
Bioorg. Med. Chem. Lett.,
Vol. 15,
pp. 2601-2605,
2005.
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Ishikawa, T.,
Tamura, A.,
Saito, H.,
Wakabayashi, K.,
Nakagawa, H..
Pharmacogenomics of the Human ABC Transporter ABCG2: From Functional Evaluation to Drug Molecular Design.,
Naturwissenschaften,
Vol. 14,
pp. 1-13,
2005.
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HIROSHI NAKAGAWA.
Inhibitory effects of mevastatin and a geranylgeranyl transferase I inhibitor (GGTI-2166) on mononuclear osteoclast formation induced by receptor activator of NFkappaB ligand (RANKL) or tumor necrosis factor-alpha (TNF-alpha).,
Biochem Pharmacol.,
Vol. 69,
No. 1,
pp. 87-95,
2005.
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Nakagawa, H.,
Hasumi, K.,
Woo, J.-T.,
Nagai, K.,
Wachi, M..
Generation of hydrogen peroxide primarily contributes to the induction of Fe(II)-dependent apoptosis in Jurkat cells by (-)-epigallocatechin gallate,
Carcinogenesis,
Vol. 25,
No. 9,
pp. 1567-1574,
Sept. 2004.
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HIROSHI NAKAGAWA.
Generation of hydrogen peroxide primarily contributes to the induction of Fe(II)-dependent apoptosis in Jurkat cells by (-)-epigallocatechin gallate.,
Carcinogenesis,
Vol. 25,
No. 9,
pp. 1567-1574,
2004.
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HIROSHI NAKAGAWA.
Quercetin suppresses bone resorption by inhibiting differentiation and activation of osteoclasts.,
Biological Pharm. Bull.,
Vol. 27,
No. 4,
pp. 504-509,
2004.
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HIROSHI NAKAGAWA.
Destruxins, cyclodepsipeptides, block the formation of actin rings, and prominent clear zones and ruffled borders in osteoclasts.,
Bone,
Vol. 33,
pp. 443-455,
2003.
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HIROSHI NAKAGAWA.
Fenton reaction is primarily involved in a mechanism of (-)-epigallocatechin-3-gallate to induce osteoclastic cell death.,
Biochem. Biophys. Res. Commun.,
Vol. 292,
pp. 94-101,
2002.
著書
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中川大,
永井和夫.
茶の効能と応用開発・破骨細胞の機能を調節する緑茶成分EGCG.,
シーエムシー出版,
pp. 196-204,
2006.
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石川智久,
櫻井亜季,
大西裕子,
中川大.
バイオインダストリー・癌の薬剤耐性機構解明から薬物トランスポーター遺伝子多型の臨床診断へ.,
シーエムシー出版,
Vol. 22,
No. 3,
pp. 11-16,
2005.
特許など
学位論文
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