@book{CTT100836461, author = {分子ロボティクス研究会: 浅沼浩之 and 遠藤政幸 and 葛谷明紀 and 小宮健 and 小長谷明彦 and 萩谷昌己 and 藤本健造 and 松浦和則 and ほか全30名}, title = {分子ロボティクス概論 ~分子のデザインでシステムをつくる}, publisher = {情報計算化学生物学会(CBI学会)出版}, year = 2019, } @book{CTT100836460, author = {多田隈尚史 and 葛谷明紀 and 川又生吹 and 村田智 and 浜田省吾 and 多田隈尚史 and 野村慎一郎 and 葛谷明紀 and 小宮健 and 川又生吹 and 中茎隆 and 角五彰 and ほか全22名}, title = {DNA分子デザインのすべて ~国際学生コンテストBIOMOD虎の巻~}, publisher = {情報計算化学生物学会(CBI学会)出版}, year = 2019, } @book{CTT100790920, author = {Hagiya, M. and Kobayashi, S. and Ken KOMIYA and Tanaka, F. and Yokomori, T.}, title = {Molecular computing machineries-computing models and wet implementations}, publisher = {}, year = 2012, } @book{CTT100681408, author = {小宮健 and 瀧ノ上正浩 and 田中文昭 and 浜田省吾 and 村田智}, title = {DNAナノエンジニアリング}, publisher = {近代科学社}, year = 2011, } @book{CTT100681407, author = {Masami Hagiya and Satoshi Kobayashi and Ken Komiya and Fumiaki Tanaka and Takashi Yokomori}, title = {Chapter 34. Molecular Computing Machineries -- Computing Models and Wet Implementations}, publisher = {Springer-Verlag}, year = 2010, } @article{CTT100823865, author = {池田 亮太 and 小林 聡 and 小宮 健}, title = {Hill型の融解曲線をもつDNA塩基配列の設計}, journal = {研究報告バイオ情報学(BIO)}, year = 2019, } @article{CTT100798787, author = {Ken KOMIYA}, title = {Measurement of microRNA with isothermal DNA amplification on fully automated immunoassay analyzers}, journal = {Analytical and Bioanalytical Chemistry}, year = 2019, } @article{CTT100808350, author = {Yusuke Sato and Ken Komiya and Ibuki Kawamata and Satoshi Murata and Shin-ichiro M. Nomura}, title = {Isothermal amplification of specific DNA molecules inside giant unilamellar vesicles}, journal = {Chemical Communications}, year = 2019, } @article{CTT100798414, author = {Ken KOMIYA and M. Komori and C. Noda and S. Kobayashi and T. Yoshimura and M. Yamamura}, title = {Leak-free million-fold DNA amplification with locked nucleic acid and targeted hybridization in one pot}, journal = {Organic & Biomolecular Chemistry}, year = 2019, } @article{CTT100798415, author = {Kimoto, N. and Ken KOMIYA and Fujimoto, K. and Kobayashi, S.}, title = {Monotonically controlling right linear grammars with unknown behaviors to output a target string}, journal = {Theoretical Computer Science}, year = 2019, } @article{CTT100823867, author = {木元達哉 and 小宮健 and 藤本健造 and 小林 聡}, title = {未知の振る舞いを持つ正則文法とその制御}, journal = {電子情報通信学会技術研究報告}, year = 2018, } @article{CTT100823866, author = {矢光隆太郎 and 小宮健 and 藤本健造 and 小林 聡}, title = {反応システムの制御によるブール関数の計算}, journal = {電子情報通信学会技術研究報告}, year = 2018, } @article{CTT100758069, author = {ジョン A. ローズ and Ken KOMIYA and Satoshi Kobayashi}, title = {Engineering multistate DNA molecules: a tunable thermal band-pass filter}, journal = {Micro & Nano Letters}, year = 2016, } @article{CTT100758066, author = {Ken KOMIYA and MASAYUKI YAMAMURA}, title = {Cascading DNA Generation Reaction for Controlling DNA Nanomachines at a Physiological Temperature}, journal = {New Generation Computing}, year = 2015, } @article{CTT100598122, author = {小宮健 and ジョン A. ローズ and 山村雅幸}, title = {自律DNA分子計算 ‐ in vitro インテリジェンスの構築}, journal = {計測自動制御学会論文集}, year = 2010, } @article{CTT100598120, author = {Ken Komiya and Masayuki Yamamura and John A. Rose}, title = {Experimental Validation and Optimization of Signal Dependent Operation in Whiplash PCR}, journal = {Natural Computing}, year = 2010, } @article{CTT100681399, author = {Ken KOMIYA and MASAYUKI YAMAMURA and John A. Rose}, title = {Quantitative design and experimental validation for a single-molecule DNA nanodevice transformable among three structural states}, journal = {Nucleic Acids Research}, year = 2010, } @article{CTT100598118, author = {Ken Komiya and Masayuki Yamamura and John A. Rose}, title = {Experimental Validation of Signal Dependent Operation in Whiplash PCR}, journal = {Lecture Notes in Computer Science}, year = 2008, } @article{CTT100576773, author = {Hiroyuki Sekiguchi and Daisuke Kiga and Ken Komiya and Masayuki Yamamura}, title = {A Design and Feasibility Study of Reactions Comprising DNA Molecular Machine that Walks Autonomously by using a Restriction Enzyme}, journal = {Natural Computing}, year = 2008, } @article{CTT100576774, author = {K. Komiya and N. Hirayama and M. Yamamura}, title = {An Interface for a Computing Model Using Methylation to Allow Precise Population Control by Quantitative Monitoring}, journal = {Lecture Notes on Computer Science}, year = 2007, } @article{CTT100598116, author = {Hiroyuki Sekiguchi and Ken Komiya and Daisuke Kiga and Masayuki Yamamura}, title = {A realization of DNA molecular machine that walks autonomously by using a restriction enzyme}, journal = {Lecture Notes in Computer Science}, year = 2007, } @article{CTT100532034, author = {Ken Komiya and Satsuki Yaegashi and Masami Hagiya and Akira Suyama and John A. Rose}, title = {Experimental Validation of the Statistical Thermodynamic Model for Prediction of the Behavior of Autonomous Molecular Computers Based on DNA Hairpin Formation}, journal = {Lecture Notes in Computer Science}, year = 2006, } @article{CTT100532035, author = {John A. Rose and Ken Komiya and Satsuki Yaegashi and Masami Hagiya}, title = {Displacement Whiplash PCR: Optimized Architecture and Experimental Validation}, journal = {Lecture Notes in Computer Science}, year = 2006, } @article{CTT100541977, author = {Ken Komiya and Kensaku Sakamoto and Atsushi Kameda and Msasahito Yamamoto and Azuma Ohuchi and Daisuke Kiga and Shigeyuki Yokoyama and Masami Hagiya}, title = {DNA polymerase programmed with a hairpin DNA incorporates a multiple-instruction architcture into molecular computing}, journal = {BioSystems}, year = 2006, } @article{CTT100598113, author = {Masami Hagiya and John A. Rose and Ken Komiya and Kensaku Sakamoto}, title = {Complexity analysis of the SAT engine: DNA algorithms as probablistic algorithms}, journal = {Theoretical Computer Science}, year = 2002, } @article{CTT100541979, author = {Ken Komiya and Kensaku Sakamoto and Hidetaka Gouzu and Shigeyuki Yokoyama and Masanori Arita and Akio Nishikawa and Masami Hagiya}, title = {Successive State Transitions with I/O Interface by Molecules}, journal = {Lecture Notes in Computer Science}, year = 2001, } @article{CTT100405985, author = {Kensaku Sakamoto and Hidetaka Gouzu and Ken Komiya and Shigeyuki Yokoyama and Takashi Yokomori and Masami Hagiya}, title = {Molecular Computation by DNA Hairpin Formation}, journal = {Science}, year = 2000, } @article{CTT100598112, author = {Kensaku Sakamoto and Daisuke Kiga and Ken Komiya and Hidetaka Gouzu and Shigeyuki Yokoyama and Shuji Ikeda and Hiroshi Sugiyama and Masami Hagiya}, title = {State Transitions by Molecules}, journal = {Biosystems}, year = 1999, } @inproceedings{CTT100836464, author = {小宮健}, title = {分子ロボット将来像の共創に向けて}, booktitle = {}, year = 2020, } @inproceedings{CTT100836463, author = {Shuntaro Sato and Masayuki Yamamura and Ken Komiya}, title = {Optimization of the multi-step DNA computing reaction using oxDNA MD simulation}, booktitle = {}, year = 2020, } @inproceedings{CTT100836462, author = {Shuntaro Sato and Masayuki Yamamura and Ken Komiya}, title = {Optimization of the multi-step DNA computing reaction that implements a state machine}, booktitle = {}, year = 2020, } @inproceedings{CTT100836465, author = {小宮健}, title = {持続可能な薬剤分子合成からIoTデバイス製造まで、DNAナノテクノロジーが可能にする次世代の微細加工技術}, booktitle = {}, year = 2020, } @inproceedings{CTT100823868, author = {小宮健}, title = {核酸素子で生命のソフトウェア工学を探究する}, booktitle = {}, year = 2020, } @inproceedings{CTT100823869, author = {小宮健}, title = {分⼦からIoTまで、ものつくりのシンギュラリティ}, booktitle = {}, year = 2019, } @inproceedings{CTT100808358, author = {Ken KOMIYA and Noda Chizuru and Teruya Enomoto and MASAYUKI YAMAMURA}, title = {Experimental Investigation of DNA Generation Circuits toward Molecular Robot Control}, booktitle = {}, year = 2019, } @inproceedings{CTT100808356, author = {Ken KOMIYA and Teruya Enomoto and MASAYUKI YAMAMURA}, title = {Characterization of DNA Generation Circuits for Controlling DNA Nanodevices}, booktitle = {}, year = 2019, } @inproceedings{CTT100808355, author = {Yuske Sato and Ken Komiya and Ibuki Kawamata and Satoshi Murata and Shin-Ichiro M. Nomura}, title = {Amplification of specific DNA molecules inside giant unilamellar vesicles at isothermal and physiological temperature}, booktitle = {}, year = 2019, } @inproceedings{CTT100808353, author = {小宮健}, title = {分子生産からIoTまで、DNAナノテクノロジーが可能にする次世代の微細加工技術}, booktitle = {}, year = 2019, } @inproceedings{CTT100808351, author = {Ken Komiya and Teruya Enomoto and Masayuki Yamamura}, title = {Construction of DNA Amplification Circuit for Directing DNA Nanodevices and Quantifying Nucleic Acids}, booktitle = {}, year = 2019, } @inproceedings{CTT100798416, author = {榎本輝也 and 山村雅幸 and 小宮健}, title = {微小チャンバーを用いた低温増幅反応による核酸のデジタル計測技術の開発}, booktitle = {}, year = 2019, } @inproceedings{CTT100808354, author = {榎本輝也 and 小宮健 and 山村雅幸}, title = {細胞サイズのチャンバー内における等温核酸増幅反応とデジタル計測技術の開発}, booktitle = {}, year = 2019, } @inproceedings{CTT100808352, author = {小宮健}, title = {分子ロボット研究者のための技術倫理綱領の策定}, booktitle = {}, year = 2019, } @inproceedings{CTT100785080, author = {小宮健}, title = {DNAによるナノ構造の時空間プログラミングと知的機能の創製}, booktitle = {}, year = 2018, } @inproceedings{CTT100785067, author = {Ken KOMIYA}, title = {Construction of a DNA Generation Circuit toward Engineering of DNA-based Signal Transduction Systems}, booktitle = {}, year = 2018, } @inproceedings{CTT100785001, author = {Teruya Enomoto and Ken Komiya}, title = {Experimental investigation on encapsulation of isothermal nucleic acid amplification reaction into tiny chambers}, booktitle = {}, year = 2018, } @inproceedings{CTT100785068, author = {小宮健 and 榎本輝也 and 曽我直樹 and 田端和仁 and 野地博行 and 山村雅幸}, title = {細胞サイズの液滴内における等温DNA増幅反応挙動の検証}, booktitle = {}, year = 2018, } @inproceedings{CTT100785069, author = {佐藤佑介 and 小宮健 and 川又生吹 and 村田智 and 野村 M. 慎一郎}, title = {分子ロボットへの信号DNA増幅機構の実装に向けて}, booktitle = {}, year = 2018, } @inproceedings{CTT100785081, author = {小宮健}, title = {低コストな高感度核酸検査を実現する等温指数増幅法の開発}, booktitle = {}, year = 2017, } @inproceedings{CTT100785071, author = {Yusuke Sato and Yuki Suzuki and Ibuki Kawamata and Satoshi Murata and Yuichi Hiratsuka and Ken Komiya and Masayuki Endo and Shin-ichiro M. Nomura}, title = {Development of a cell-sized molecular robot controlled by an external molecular signal}, booktitle = {}, year = 2017, } @inproceedings{CTT100785070, author = {Ken Komiya and Satoshi Kobayashi and John A. Rose}, title = {Engineering thermal response of a DNA nanodevice}, booktitle = {}, year = 2017, } @inproceedings{CTT100785074, author = {小宮健 and 若林優太 and 山村雅幸}, title = {翻訳機構の進化過程解明に向けたリボソームの立体構造比較}, booktitle = {}, year = 2016, } @inproceedings{CTT100785072, author = {若林優太 and 小宮健 and 山村雅幸}, title = {好熱性細菌を対象としたリボソームの立体構造比較}, booktitle = {}, year = 2016, } @inproceedings{CTT100785000, author = {Ibuki Kawamata and Shota Kawakami and Yu-Chin Chen and Shogo Hiratsuka and Sho Aradachi and Daisuke Tamatsuki and Hayato Yuuki and Takuto Takahashi and Eiki Ishihara and Shunsuke Imai and Hayato Otaka and Yuto Otak and Kenta Suzuki and Taiki Watanabe and Ken Komiya and Fumi Takabatake and Shin-Ichiro Nomura and Satoshi Murata}, title = {Autonomous and Programmable Strand Generator Implemented as DNA Chemical Reaction Network}, booktitle = {}, year = 2016, } @inproceedings{CTT100785082, author = {小宮健 and 藤本健造}, title = {分子ロボットの知能となる分子制御回路の構築}, booktitle = {}, year = 2016, } @inproceedings{CTT100785075, author = {Ken Komiya and Chizuru Noda and Makoto Komori and Kesu Dong and Toshio Takenaka and Teruya Enomoto and Toru Yoshimura and Masayuki Yamamura}, title = {Construction of an isothermal DNA amplification reaction system for simplified nucleic acid test}, booktitle = {}, year = 2016, } @inproceedings{CTT100758068, author = {ジョン A. ローズ and Ken KOMIYA}, title = {Analysis and Design of a Single-Molecule DNA Nanodevice for Thermal Band-Pass Filters}, booktitle = {}, year = 2016, } @inproceedings{CTT100785083, author = {小宮健 and 藤本健造}, title = {分子ロボットの知能となる分子制御回路の構築}, booktitle = {}, year = 2016, } @inproceedings{CTT100785077, author = {Ken Komiya and Chizuru Noda and Masayuki Yamamura}, title = {Construction of a DNA Generation Circuit for a Molecular Robot}, booktitle = {}, year = 2015, } @inproceedings{CTT100785078, author = {Ken Komiya and Kesu Dong and Toshio Takenaka and Masayuki Yamamura}, title = {Construction of a DNA generation reaction system for autonomous DNA-based computing at a physiological temperature}, booktitle = {}, year = 2015, } @inproceedings{CTT100785079, author = {Ken Komiya and Makoto Komori and Erimi Harada and Takashi Nemoto and Masayuki Yamamura and Toru Yoshimura}, title = {Construction of an isothermal exponential amplification reaction system for highly sensitive nucleic acid test}, booktitle = {}, year = 2015, } @inproceedings{CTT100681405, author = {外舘悠仁 and 小宮健 and 山村雅幸}, title = {DNAナノマシンによる歩行動作の温度特性の検証}, booktitle = {日本機械学会 第6回マイクロ・ナノ工学シンポジウム講演論文集}, year = 2014, } @inproceedings{CTT100681402, author = {Satoshi Kobayashi and Kazuya Yanagibashi and Kenzo Fujimoto and Ken Komiya and Masami Hagiya}, title = {Analog DNA Computing Devices Toward the Control of Molecular Robots}, booktitle = {Proceedings of Workshop on Self-organization in Swarm of Robots: from Molecular Robots to Mobile Agents (WSSR 2014)}, year = 2014, } @inproceedings{CTT100681404, author = {小宮健 and 山村雅幸}, title = {DNA応答型ナノマシンの動作を指定するDNAシグナル生成機構の構築}, booktitle = {日本機械学会 第6回マイクロ・ナノ工学シンポジウム講演論文集}, year = 2014, } @inproceedings{CTT100681443, author = {Ken KOMIYA}, title = {Implementation of in vitro intelligence for real-time operation of molecular robots}, booktitle = {}, year = 2014, } @inproceedings{CTT100681442, author = {Ken KOMIYA}, title = {Implementation of in vitro intelligence for controlling molecular robots}, booktitle = {}, year = 2013, } @inproceedings{CTT100681441, author = {小宮健}, title = {分子ロボットの知能}, booktitle = {}, year = 2012, } @inproceedings{CTT100681440, author = {小宮健}, title = {分子ロボットの実現に向けたDNA論理ゲートの現状と課題}, booktitle = {}, year = 2012, } @inproceedings{CTT100681438, author = {Ken KOMIYA and Asako Kobayashi and Masayuki Yamamura}, title = {Construction of molecular modules for an intelligent molecular robot that implements sensing, judgment and synthesis for controlling biological events without human intervention}, booktitle = {}, year = 2011, } @inproceedings{CTT100681447, author = {Ken KOMIYA and Asako Kobayashi and Masayuki Yamamura}, title = {Construction of a molecular robot system that autonomously monitors, judges, and controls biomolecular reaction}, booktitle = {}, year = 2011, } @inproceedings{CTT100681439, author = {Ken KOMIYA}, title = {Innovation of a Molecular Robot Based on Dynamical DNA Nanotechnology for Achieving an Embedded Controller of Molecular Reaction}, booktitle = {}, year = 2011, } @inproceedings{CTT100681401, author = {Ryo Hirose and Satoshi Kobayashi and Ken Komiya}, title = {DNA Logic Circuits with a DNA Polymerase and a Nicking Enzyme}, booktitle = {Proceedings of the 2011 International Conference on Parallel and Distributed Processing Techniques and Applications (PDPTA'11)}, year = 2011, } @inproceedings{CTT100681406, author = {Toshikazu Taki and Ken Komiya and Masayuki Yamamura}, title = {Autonomous Restoration of a DNA Track for a Sustained Walk of a DNA Walking Device Driven by Nicking Reaction}, booktitle = {8th Annual Conference on Foundation of Nanoscience (FNANO11)}, year = 2011, } @inproceedings{CTT100681448, author = {Ken KOMIYA and Masayuki Yamamura and John. A. Rose}, title = {Thermal band pass filter implemented with a bistable DNA}, booktitle = {}, year = 2009, } @inproceedings{CTT100576776, author = {Masayuki Yamamura and Noriko Hirayama and Ken Komiya}, title = {An Implementation of Aqueous Memory Molecules with Light Responsive DNAs}, booktitle = {Proceedings of 2007 IEEE Congress on Evolutionary Computation (CEC2007)}, year = 2007, } @inproceedings{CTT100681437, author = {Ken KOMIYA and Kensaku Sakamoto and Shigeyuki Yokoyama and John A. Rose and Masami Hagiya}, title = {Single-Molecule Architcture for a DNA State Machine: Whiplash PCR}, booktitle = {The First International Conference on Biocomputers (Biocomputers 2004)}, year = 2004, } @inproceedings{CTT100598111, author = {Mitsuhiro Kubota and Kazumasa Ohtake and Ken Komiya and Kensaku Sakamoto and Masami Hagiya}, title = {Branching DNA Machines Based on Transitions of Hairpin Structures}, booktitle = {Proceedings of 2003 Congress on Evolutionary Computation (CEC2003)}, year = 2003, } @inproceedings{CTT100681400, author = {Ken KOMIYA and Kensaku Sakamoto and Daisuke Kiga and Shigeyuki Yokoyama}, title = {Evaluation of the potential of an autonomous DNA computer on the basis of molecular biology experiments}, booktitle = {Proceedings of Eighth International Meeting on DNA Based Computers (DNA8)}, year = 2002, } @inproceedings{CTT100598129, author = {坂本 健作 and 小宮 健 and 横山 茂之 and 萩谷 昌己}, title = {DNA分子の自己会合反応の解析}, booktitle = {情報処理学会シンポジウムシリーズ}, year = 2000, } @inproceedings{CTT100598128, author = {萩谷 昌己 and 小宮 健 and 坂本 健作}, title = {SAT Engineの計算量の解析 −確率アルゴリズムとしてのDNAアルゴリズム−}, booktitle = {情報処理学会シンポジウムシリーズ}, year = 2000, } @inproceedings{CTT100598110, author = {Masanori Arita and Akio Nishikawa and Masami Hagiya and Ken Komiya and Kensaku Sakamoto and Hidetaka Gouzu and Shigeyuki Yokoyama}, title = {Improving Sequence Design for DNA Computing}, booktitle = {Proceetings of Fifth Genetic and Evolutionary Computation Conference (GECCO2000)}, year = 2000, } @misc{CTT100785066, author = {小宮健}, title = {DNAナノマシン}, year = 2016, } @misc{CTT100798417, author = {小宮健}, title = {分子プログラミング、分子ロボティクスと高感度に核酸を検出する等温指数増幅反応系の構築}, year = 2015, } @misc{CTT100798418, author = {小宮健}, title = {高感度核酸検査に向けた等温指数増幅反応系の構築}, year = 2015, } @misc{CTT100785065, author = {小宮健}, title = {ナノサイズの「DNAからくり箱」が患部にお届けします}, year = 2013, } @misc{CTT100681446, author = {小宮健}, title = {大学生のうちに世界と闘おう!: 国際生体分子デザインコンペテイション BIOMOD}, year = 2013, } @misc{CTT100681445, author = {小宮健}, title = {分子ロボット創製に向けた動的DNAナノテクノロジーの展開}, year = 2012, } @misc{CTT100681444, author = {小宮健}, title = {分子計算}, year = 2010, } @misc{CTT100594451, author = {Ken KOMIYA}, title = {自律的にプログラムを実行する分子機械の一本鎖DNA分子を用いた分子実装}, year = 2004, } @misc{CTT100842086, author = {小宮健}, title = {DNAの酵素合成法}, howpublished = {公開特許}, year = 2020, month = {}, note = {特願2019-049824(2019/03/18), 特開2020-150801(2020/09/24)} } @misc{CTT100756287, author = {小宮健}, title = {標的核酸の検出方法及びキット }, howpublished = {登録特許}, year = 2020, month = {}, note = {特願2017-076848(2017/04/07), 特開2017-136086(2017/08/10), 特許第6638122号(2020/01/07)} } @misc{CTT100759970, author = {小宮健 and 吉村 徹  and 小森 誠}, title = {ポリDNAスペーサー配列を有する配列変換およびシグナル増幅DNAならびにそれらを用いた検出方法}, howpublished = {登録特許}, year = 2020, month = {}, note = {特願2017-519832(2015/10/13), 特表2017-532044(2017/11/02), 特許第6773651号(2020/10/05)} } @misc{CTT100758863, author = {小宮健 and 吉村 徹  and 小森 誠}, title = {ロックされた核酸を有する配列変換およびシグナル増幅DNAならびにそれを用いた検出方法}, howpublished = {登録特許}, year = 2021, month = {}, note = {特願2017-519860(2015/10/13), 特開特表2017-530715(2017/10/19), 特許第6896620号(2021/06/11)} } @misc{CTT100742129, author = {小宮健 and 吉村 徹  and 小森 誠}, title = {カバーされた配列変換DNAおよび検出方法}, howpublished = {登録特許}, year = 2020, month = {}, note = {特願2016-538749(2015/01/15), 特開特表2017-502661(2017/01/26), 特許第6739339号(2020/07/27)} } @misc{CTT100675816, author = {小宮健}, title = {標的核酸の検出方法及びキット }, howpublished = {登録特許}, year = 2017, month = {}, note = {特願2012-547941(2011/12/12), 再表2012/077819(2014/05/22), 特許第6126381号(2017/04/14)} } @phdthesis{CTT100594451, author = {Ken KOMIYA}, title = {自律的にプログラムを実行する分子機械の一本鎖DNA分子を用いた分子実装}, school = {東京大学}, year = 2004, }