@book{CTT100777988, author = {原怜 and 久堀徹}, title = {植物におけるチオレドキシンを介したタンパク質のレドックス制御}, publisher = {}, year = 2018, } @article{CTT100899661, author = {Haruka Kono and Satoshi Hara and Tadaomi Furuta and Hiroshi Ichinose}, title = {Binding profile of quinonoid-dihydrobiopterin to quinonoid-dihydropteridine reductase examined by in silico and in vitro analyses}, journal = {J Biochem}, year = 2023, } @article{CTT100917357, author = {Yuka Nago-Iwashita and Moriya Y and Hara S and Ogawa R and Aida R and Miyajima K and Shimura T and Muramatsu SI and Ide S and Ikeda K and Ichinose H}, title = {Overexpression of tyrosine hydroxylase in dopaminergic neurons increased sensitivity to methamphetamine}, journal = {Neurochemistry International}, year = 2023, } @article{CTT100895508, author = {Madokoro Y and Kamikokuryo C and Niiyama S and Ito T and Hara S and Ichinose H and Kakihana Y}, title = {Early ascorbic acid administration prevents vascular endothelial cell damage in septic mice}, journal = {Front Pharmacol}, year = 2022, } @article{CTT100879330, author = {Miyajima K and Sudo Y and Sanechika S and Hara Y and Horiguchi M and Xu F and Suzuki M and Hara S and Tanda K and Inoue KI and Takada M and Yoshioka N and Takebayashi H and Mori-Kojima M and Sugimoto M and Sumi-Ichinose C and Kondo K and Takao K and Miyakawa T and Ichinose H.}, title = {Perturbation of monoamine metabolism and enhanced fear responses in mice defective in the regeneration of tetrahydrobiopterin}, journal = {Journal of neurochemistry}, year = 2022, } @article{CTT100879322, author = {Hara S and Sanatani T and Tachikawa N and Yoshimura Y and Miyata N and Sasaki H and Kuroda R and Kamikokuryo C and Eguchi T and Niiyama S and Kakihana Y and Ichinose H.}, title = {Comparison of the levels of neopterin, CRP, and IL-6 in patients infected with and without SARS-CoV-2.}, journal = {Heliyon}, year = 2022, } @article{CTT100879331, author = {Inukai S and Hara S and Ichinose H.}, title = {Tyrosine hydroxylase activity is regulated through the modification of the 176th cysteine residue}, journal = {Biochem Biophys Res Commun.}, year = 2022, } @article{CTT100856882, author = {Miyajima K and Kawamoto C and Hara S and Mori-Kojima M and Ohye T and Sumi-Ichinose C and Saito N and Sasaoka T and Metzger D and Ichinose H}, title = {Tyrosine hydroxylase conditional knockout mice reveal peripheral tissue-dependent differences in dopamine biosynthetic pathways}, journal = {}, year = 2021, } @article{CTT100832289, author = {hirokazu arai and rina takahashi and yoshiaki sakamoto and tatsuya kitano and okishi mashita and satoshi hara and satoru yoshikawa and koh kawasaki and hiroshi ichinose}, title = {Peripheral tetrahydrobiopterin is involved in the pathogenesis of mechanical hypersensitivity in a rodent postsurgical pain model}, journal = {Pain}, year = 2020, } @article{CTT100819686, author = {Zhang L and Hara S and Ichinose H and Nagashima D and Morita K and Sakurai T and Ichihara S and Ichihara G.}, title = {Exposure to acrylamide decreases noradrenergic axons in rat brain.}, journal = {NEUROTOXICOLOGY}, year = 2020, } @article{CTT100813612, author = {Takeshita N and Kawade N and Suzuki W and Hara S and Horio F and Ichinose H}, title = {Deficiency of ascorbic acid decreases the contents of tetrahydrobiopterin in the liver and the brain of ODS rats.}, journal = {Neuroscience letters}, year = 2020, } @article{CTT100819685, author = {Yokochi Y and Sugiura K and Takemura K and Yoshida K and Hara S and Wakabayashi KI and Kitao A and Hisabori T}, title = {Impact of key residues within chloroplast thioredoxin-f on recognition for reduction and oxidation of target proteins.}, journal = {J BIOL CHEM}, year = 2019, } @article{CTT100838785, author = {Yoshida K and Uchikoshi E and Hara S and Hisabori T.}, title = {Thioredoxin-like2/2-Cys peroxiredoxin redox cascade acts as oxidative activator of glucose-6-phosphate dehydrogenase in chloroplasts.}, journal = {Biochemical Journal}, year = 2019, } @article{CTT100790686, author = {Kurosaki H and Yamaguchi K and Man-Yoshi K and Muramatsu SI and Hara S and Ichinose H}, title = {Administration of tetrahydrobiopterin restored the decline of dopamine in the striatum induced by an acute action of MPTP.}, journal = {Neurochemistry International}, year = 2019, } @article{CTT100783839, author = {Hara S and Fukumura S and Ichinose H}, title = {Reversible S-glutathionylation of human 6-pyruvoyl tetrahydropterin synthase protects its enzymatic activity}, journal = {Journal of Biological Chemistry}, year = 2019, } @article{CTT100777986, author = {宮嶋克也 and 原怜 and 一瀬宏}, title = {葉酸代謝はオリゴデンドロサイトの分化や生存を制御している}, journal = {}, year = 2018, } @article{CTT100777981, author = {Murakami Satoshi and Kondo K and Katayama S and Satoshi Hara and sunamura EI and Yamashita E and Groth G and TORU HISABORI}, title = {Structure of the γ-ε complex of cyanobacterial F1-ATPase reveals a suppression mechanism of the γ subunit on ATP-hydrolysis in phototrophs}, journal = {Biochemical Journal}, year = 2018, } @article{CTT100777985, author = {竹下直輝 and 原怜 and 一瀬宏}, title = {キサンツレン酸はビオプテリン生合成酵素の阻害作用を持つ}, journal = {ビタミン}, year = 2017, } @article{CTT100777980, author = {Seta, Atsushi and Tabara, Midori and Nishibori, Yuki and Hiraguri, Akihiro and Ohkama-Ohtsu, Naoko and Yokoyama, Tadashi and Satoshi Hara and Yoshida, Keisuke and TORU HISABORI and Fukudome, Akihito and Koiwa, Hisashi and Moriyama, Hiromitsu and Takahashi, Nobuhiro and Fukuhara, Toshiyuki}, title = {Post-translational regulation of the dicing activities of Arabidopsis DICER-LIKE 3 and 4 by inorganic phosphate and the redox state}, journal = {Plant and Cell Physiology}, year = 2017, } @article{CTT100753577, author = {Keiko Imamura and Takayuki Kondo and Yasushi Koshiba and Satoshi Hara and Hiroshi Ichinose and Mahoko Furujo and Masako Kinoshita and Tomoko Oeda and Jun Takahashi and Ryosuke Takahashi and Haruhisa Inoue}, title = {Genetic and pharmacological correction of aberrant dopamine synthesis using patient iPSCs with BH4 metabolism disorders.}, journal = {Human Molecular Genetics}, year = 2016, } @article{CTT100718630, author = {加藤北都 and 原怜 and 一瀬宏}, title = {パーキンソン病動物モデルにおけるイソチオシアネートの神経保護作用について}, journal = {ビタミン}, year = 2016, } @article{CTT100777978, author = {Yoshida K and Satoshi Hara and Hisabori T}, title = {Thioredoxin Selectivity for Thiol-Based Redox Regulation of Target Proteins in Chloroplasts}, journal = {J Biol Chem.}, year = 2015, } @article{CTT100777977, author = {Satoshi Hara and Y. Tatenaka and Y. Ohuchi and T. Hisabori}, title = {Direct determination of the redox status of cysteine residues in proteins in vivo}, journal = {Biochem Biophys Res Commun}, year = 2015, } @article{CTT100777984, author = {原怜 and 久堀徹}, title = {タンパク質中のチオール基の酸化還元状態を可視化・定量するDNAマレイミドの開発}, journal = {生物物理化学}, year = 2014, } @article{CTT100777976, author = {Keisuke Yoshida and Yuta Matsuoka and Satoshi Hara and Hiroki Konno and Toru Hisabori}, title = {Distinct Redox Behaviors of Chloroplast Thiol Enzymes and their Relationships with Photosynthetic Electron Transport in Arabidopsis thaliana.}, journal = {Plant and Cell Physiology}, year = 2014, } @article{CTT100777975, author = {Satoshi Hara and T. Hisabori}, title = {Kinetic analysis of the interactions between plant thioredoxin and target proteins}, journal = {Front Plant Sci}, year = 2013, } @article{CTT100777974, author = {Y. Tsukamoto and Y. Fukushima and Satoshi Hara and T. Hisabori}, title = {Redox control of the activity of phosphoglycerate kinase in Synechocystis sp. PCC6803.}, journal = {Plant Cell Physiol}, year = 2013, } @article{CTT100653747, author = {Satoshi Hara and T. Nojima and KOHJI SEIO and MASASUKE YOSHIDA and TORU HISABORI}, title = {DNA-maleimide: An improved maleimide compound for electrophoresis-based titration of reactive thiols in a specific protein}, journal = {Biochimica Et Biophysica Acta-General Subjects}, year = 2013, } @article{CTT100777973, author = {S. Kikutani and R. Tanaka and Y. Yamazaki and Satoshi Hara and T. Hisabori and P. G. Kroth and Y. Matsuda}, title = {Redox regulation of carbonic anhydrases via thioredoxin in the chloroplast of the marine diatom Phaeodactylum tricornutum.}, journal = {J Biol Chem}, year = 2012, } @article{CTT100777971, author = {H. Konno and T. Nakane and M. Yoshida and H. Ueoka-Nakanishi and Satoshi Hara and T. Hisabori}, title = {Thiol modulation of the chloroplast ATP synthase dependent on the membrane energization of thylakoid membranes.}, journal = {Plant Cell Physiol}, year = 2012, } @article{CTT100777970, author = {Satoshi Hara and Motohashi K and Arisaka F and Romano PG and Hosoya-Matsuda N and Kikuchi N and Fusada N and Hisabori T}, title = {Thioredoxin-h1 reduces and reactivates the oxidized cytosolic malate dehydrogenase dimer in higher plants.}, journal = {Journal of Biological Chemistry}, year = 2006, } @article{CTT100777982, author = {Hisabori, T. and Satoshi Hara and Fujii, T. and Yamazaki, D. and Hosoya-Matsuda, N. and Motohashi, K.}, title = {Thioredoxin affinity chromatography: a useful method for further understanding the thioredoxin network.}, journal = {Journal of Experimental Botany}, year = 2005, } @inproceedings{CTT100909300, author = {Haruka Kono and Satoshi Hara and Tadaomi Furuta and Hiroshi Ichinose}, title = {Analysis of the binding profile of quinonoid-form of dihydropteridine to quinonoid-dihydropteridine reductase}, booktitle = {}, year = 2023, } @inproceedings{CTT100906078, author = {河野はるか and 原怜 and 古田忠臣 and 一瀬宏}, title = {葉酸代謝とビオプテリン代謝の接点}, booktitle = {}, year = 2023, } @inproceedings{CTT100799508, author = {河野はるか and 原怜 and 古田忠臣 and 一瀬宏}, title = {分子シミュレーションによるキノノイドジヒドロプテリジン還元酵素の基質認識機構の解析}, booktitle = {}, year = 2019, } @inproceedings{CTT100800123, author = {河野はるか and 古田忠臣 and 原怜 and 一瀬宏}, title = {キノノイドジヒドロプテリジン還元酵素の基質認識機構の解析}, booktitle = {}, year = 2019, } @misc{CTT100831057, author = {一瀬宏 and 原怜 and 吉田 勇輝 and 村松 慎一 and 加藤 節子}, title = {SPRをコードするポリヌクレオチドを含む組み換えベクター、及びそれを含む組成物}, howpublished = {公開特許}, year = 2020, month = {}, note = {特願2018-206643(2018/11/01), 特開2020-068734(2020/05/07)} } @misc{CTT100675803, author = {久堀徹 and 原怜 and 野島達也}, title = {タンパク質のチオール基の酸化還元状態を検出する方法、並びにそれに用いられる試薬及びキット }, howpublished = {登録特許}, year = 2017, month = {}, note = {特願2013-166448(2013/08/09), 特開2014-081360(2014/05/08), 特許第6146742号(2017/05/26)} }