@book{CTT100811738, author = {Yoshiaki Masaki and Akihiro Ohkubo and Kohji Seio and Mitsuo Sekine}, title = {Effects of 2'-O-Modifications on RNA Duplex Stability}, publisher = {Springer}, year = 2018, } @book{CTT100785543, author = {Ohkubo Akihiro and Okamoto Itaru and Kasuya Rintaro and Sakamoto Kazushi and Sasami Takeshi and Odawara Yoko and Masaki Yoshiaki and Sakaue Toshiyuki and Nagasawa Hiroshi and Tsukahara Toshifumi and Seio Kohji and Sekine Mitsuo}, title = {Protected DNA probes (PDP): A new strategy for gene detection}, publisher = {}, year = 2008, } @article{CTT100926151, author = {Miyaji K and Masaki Y and Seio K}, title = {Inhibitory Effects on RNA Binding and RNase H Induction Activity of Prodrug-Type Oligodeoxynucleotides Modified with a Galactosylated Self-Immolative Linker Cleavable by β-Galactosidase}, journal = {Bioconjugate Chemistry}, year = 2024, } @article{CTT100926162, author = {Noguchi M and Miyauchi A and Masaki Y and Sakaki M and Lei XF and Kobayashi-Tanabe M and Miyazaki A and Aoki T and Yoshida H and Seio K and Kim-Kaneyama Jr}, title = {Hic-5 antisense oligonucleotide inhibits advanced hepatic fibrosis and steatosis in vivo}, journal = {JHEP Reports}, year = 2024, } @article{CTT100917135, author = {Takayuki Kanagawa and Shigetoshi Tachibana and Yoshiaki Masaki and Kohji Seio}, title = {Synthesis and Conformational Analyses of Cyclonucleoside Having 13-Membered Ring Bridging Nucleobase and 5′-Position via a Linker Containing Sulfonamide}, journal = {Org. Lett.}, year = 2023, } @article{CTT100895475, author = {Kanagawa T and Koyoma A and Masaki Y and Seio K}, title = {Alteration of target cleavage patterns and off-target reduction of antisense oligonucleotides incorporating 2- N-carbamoyl- or (2-pyridyl)guanine}, journal = {Org Biomol Chem .}, year = 2023, } @article{CTT100895476, author = {Tomori T and Uekusa K and Koyama A and Kanagawa T and Masaki Y and Seio K}, title = {Synthesis of 2'-O-[3-(N-methylsulfamoyl)propan-1-yl]ribothymidine as a potentially applicable 2'-modified nucleoside for antisense oligonucleotides}, journal = {Bioorg Med Chem .}, year = 2022, } @article{CTT100895472, author = {Masaki Y and Tabira A and Hattori S and Wakatsuki S and Seio K}, title = {Insertion of a methylene group into the backbone of an antisense oligonucleotide reveals the importance of deoxyribose recognition by RNase H}, journal = {Org. Biomol Chem.}, year = 2022, } @article{CTT100895471, author = {Masaki Y and Onishi Y and Seio K}, title = {Quantification of synthetic errors during chemical synthesis of DNA and its suppression by non-canonical nucleosides}, journal = {Sci Rep.}, year = 2022, } @article{CTT100878703, author = {Okamura H and Trinh GH and Dong Z and Masaki Y and Seio K and Nagatsugi F.}, title = {Selective and stable base pairing by alkynylated nucleosides featuring a spatially-separated recognition interface}, journal = {Nucleic Acids Res.}, year = 2022, } @article{CTT100878704, author = {Masaki Y and Maruyama A and Yoshida K and Tomori T and Kishimura T and Seio K.}, title = {Oligodeoxynucleotides Modified with 2'- O-(Cysteinylaminobutyl)carbamoylethylribothymidine Residues for Native Chemical Ligation with Peptide at Internal Positions}, journal = {Bioconjug. Chem.}, year = 2022, } @article{CTT100877691, author = {Kishimura T and Tomori T and Masaki Y and Seio K.}, title = {Synthesis of 2′-O-alkylcarbamoylethyl-modified oligonucleotides with enhanced nuclease resistance that form isostable duplexes with complementary RNA}, journal = {Bioorg Med Chem Lett.}, year = 2021, } @article{CTT100839578, author = {Yuko Hara and Yoshitaka Mizobe and Yukiko U. Inoue and Yasumasa Hashimoto and Norio Motohashi and Yoshiaki Masaki and Kohji Seio and Shin’ichi Takeda and Tetsuya Nagata and Matthew J. A. Wood and Takayoshi Inoue and Yoshitsugu Aoki}, title = {Novel EGFP reporter cell and mouse models for sensitive imaging and quantification of exon skipping}, journal = {}, year = 2020, } @article{CTT100836273, author = {Seio K and Yamaguchi K and Yamazaki A and Kanamori T and Masaki Y.}, title = {Transcription of DNA duplex containing deoxypseudouridine and deoxypseudoisocytidine, and inhibition of transcription by triplex forming oligonucleotide that recognizes the modified duplex}, journal = {Nucleosides, Nucleotides & Nucleic Acids}, year = 2020, } @article{CTT100836271, author = {Takeshita L and Yamada Y and Masaki Y and Seio K.}, title = {Synthesis of Deoxypseudouridine 5′-Triphosphate Bearing the Photoremovable Protecting Group at the N1 Position Capable of Enzymatic Incorporation to DNA}, journal = {J. ORG. CHEM.}, year = 2020, } @article{CTT100811721, author = {Masaki Y and Yamamoto K and Yoshida K and Maruyama A and Tomori T and Iriyama Y and Nakajima H and Kanaki T and Seio K.}, title = {Modification of oligonucleotides with weak basic residues via the 2′-O-carbamoylethyl linker for improving nuclease resistance without loss of duplex stability and antisense activity}, journal = {Org. Biomol Chem.}, year = 2019, } @article{CTT100811719, author = {Seio K and Shiozawa T and Sugiyama D and Ohno K and Tomori T and Masaki Y.}, title = {31P NMR Study on the Reactions of Amino Acids and Sugar Derivatives with Pyrophosphorous Acid as a Possible Prebiotic Phosphonylating Agent}, journal = {Bull. Chem. Soc. Jpn.}, year = 2019, } @article{CTT100812079, author = {Takashi Kanamori and Masaki Y and Oda Y and Ohzeki H and Ohkubo A and Sekine M and Seio K.}, title = {DNA triplex-based fluorescence turn-on sensors for adenosine using a fluorescent molecular rotor 5-(3-methylbenzofuran-2-yl) deoxyuridine}, journal = {Org. Biomol Chem.}, year = 2019, } @article{CTT100811709, author = {Masaki Y and Inde T and Maruyama A and Seio K.}, title = {Tolerance of N2-heteroaryl modifications on guanine bases in a DNA G-quadruplex}, journal = {Org. Biomol Chem.}, year = 2019, } @article{CTT100784916, author = {Yoshiaki Masaki and Keishi Yamamoto and Takeshi Inde and Keita Yoshida and Atsuya Maruyama and Tetsuya Nagata and Jun Tanihata and Shin'ichi Takeda and Mitsuo Sekine and Kohji Seio}, title = {Synthesis of 2'-O-(N-methylcarbamoylethyl) 5-methyl-2-thiouridine and its application to splice-switching oligonucleotides}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2018, } @article{CTT100784914, author = {Yoshiaki Masaki and Yusuke Iriyama and Hiroyuki Nakajima and Yusuke Kuroda and Tatsuro Kanaki and Satoshi Furukawa and Mitsuo Sekine and Kohji Seio}, title = {Application of 2′-O-(2-N-Methylcarbamoylethyl) Nucleotides in RNase H-Dependent Antisense Oligonucleotides}, journal = {Nucleic Acid Ther.}, year = 2018, } @article{CTT100785051, author = {Yoshiaki Masaki and Devon Cayer and Ryan McBride and M. Reza Ghadiri}, title = {A kinetically controlled, isothermal method for the detection of single nucleotide mismatches}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2018, } @article{CTT100785064, author = {K. Seio and T. Kanamori and Y. Masaki}, title = {Synthesis of Fluorescent Nucleic Acids bearing Nucleobases Modified with Heteroaryl Group and Fluorophores}, journal = {JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN}, year = 2018, } @article{CTT100784913, author = {Takahito Tomori and Kento Nagaoka and Leo Takeshita and Takashi Shiozawa and Yuya Miyatake and Yoshiaki Masaki and Mitsuo Sekine and Kohji Seio}, title = {Deoxynucleoside Triphosphate Containing Pyridazin-3-one Aglycon as a Thymidine Triphosphate Substitute for Primer Extension and Chain Elongation by Klenow fragments}, journal = {J. Org. Chem.}, year = 2018, } @article{CTT100784912, author = {Kohji Seio and Takashi Kanamori and Yoshiaki Masaki}, title = {Solvent- and environment-dependent fluorescence of modified nucleobases}, journal = {Tetrahedron Lett.}, year = 2018, } @article{CTT100785004, author = {K. Ohno and D. Sugiyama and L. Takeshita and T. Kanamori and Y. Masaki and M. Sekine and K. Seio}, title = {Synthesis of photocaged 6-O-(2-nitrobenzyl) guanosine and 4-O-(2-nitrobenzyl)uridine triphosphates for photocontrol of the RNA transcription reaction}, journal = {BIOORGANIC & MEDICINAL CHEMISTRY}, year = 2017, } @article{CTT100785010, author = {T. Inde and Y. Masaki and A. Maruyama and Y. Ito and N. Makio and Y. Miyatake and T. Tomori and M. Sekine and K. Seio}, title = {Synthesis of oligonucleotides containing 2-N-heteroarylguanine residues and their effect on duplex/triplex stability}, journal = {ORGANIC & BIOMOLECULAR CHEMISTRY}, year = 2017, } @article{CTT100785011, author = {K. Seio and M. Tokugawa and K. Kaneko and T. Shiozawa and Y. Masaki}, title = {A systematic study of the synthesis of 2'-deoxynucleosides by Mitsunobu reaction}, journal = {SYNLETT}, year = 2017, } @article{CTT100748623, author = {Takashi Kanamori and Akihiro Takamura and Nobuhiro Tago and Yoshiaki Masaki and Akihiro Ohkubo and Mitsuo Sekine and Kohji Seio}, title = {Fluorescence enhancement of oligodeoxynucleotides modified with green fluorescent protein chromophore mimics upon triplex formation.}, journal = {Org. Biomol. Chem.}, year = 2017, } @article{CTT100785546, author = {Masaki Yoshiaki and Sekine Mitsuo and Seio Kohji}, title = {Deformability Calculation for Estimation of the Relative Stability of Chemically Modified RNA Duplexes.}, journal = {Current protocols in nucleic acid chemistry}, year = 2017, } @article{CTT100724906, author = {Kohji Seio and Yurie Ohno and Kentaro Ohno and Leo Takeshita and Takashi Kanamori and Yoshiaki Masaki and Mitsuo Sekine}, title = {Photo-controlled binding of MutS to photo-caged DNA duplexes incorporating 4-O-(2-nitrobenzyl) or 4-O-[2-(2-nitrophenyl)propyl]thymidine}, journal = {Bioorganic & Medicinal Chemistry Letters}, year = 2016, } @article{CTT100722448, author = {Yoshiaki Masaki and Hugo Itou and Yuki Oda and Kazufumi Yamazaki and Nobuhiro Tago and Kentaro Ohno and Nozomi Ishii and Hirosuke Tsunoda and Takashi Kanamori and Akihiro Ohkubo and Mitsuo Sekine and Kohji Seio}, title = {Enzymatic synthesis and reverse transcription of RNAs incorporating 2'-O-carbamoyl uridine triphosphate}, journal = {Chemical Communications}, year = 2016, } @article{CTT100722454, author = {Munefumi Tokugawa and Yoshiaki Masaki and Jan Christian Canggadibrata and Kazuhei Kaneko and Takashi Shiozawa and Takashi Kanamori and Morten Grøtli and L. Marcus Wilhelmsson and Mitsuo Sekine and Kohji Seio}, title = {7-(Benzofuran-2-yl)-7-deazadeoxyguanosine as a fluorescence turn-ON probe for single-strand DNA binding protein}, journal = {Chemical Communications}, year = 2016, } @article{CTT100716346, author = {Yu Ito and Yoshiaki Masaki and Takashi Kanamori and Akihiro Ohkubo and KOHJI SEIO and MITSUO SEKINE}, title = {Synthesis of 5-[3-(2-aminopyrimidin-4-yl)aminopropyn-1-yl]uracil derivative that recognizes Ade-Thy base pairs in double-stranded DNA}, journal = {Bioorg. Med. Chem. Lett.}, year = 2016, } @article{CTT100716352, author = {Nobuhiro Tago and Yoshiaki Masaki and Takashi Kanamori and Akihiro Ohkubo and KOHJI SEIO and MITSUO SEKINE}, title = {A New Microfluidic Phase-Transfer Reaction Using HPLC Guard Columns as the Reactor for the N3 Protection of Uridine Derivatives}, journal = {SYNLETT}, year = 2015, } @article{CTT100714786, author = {Ohkubo and Kenji Yamada and Yu Ito and Kiichi Yoshimura and Koichiro Miyauchi and Takashi Kanamori and Yoshiaki Masaki and KOHJI SEIO and HIDEYA YUASA and Mitsuo}, title = {Synthesis and Triplex-forming Properties of Oligonucleotides Capable of Recognizing Corresponding DNA Duplexes Containing Four Base Pairs}, journal = {Nucleic Acids Res.}, year = 2015, } @article{CTT100716358, author = {Takahito Tomori and Yuya Miyatake and Takashi Kanamori and Yoshiaki Masaki and Akihiro Ohkubo and KOHJI SEIO and MITSUO SEKINE}, title = {Synthesis of peptide nucleic acids containing pyridazine derivatives as cytosine and thymine analogs, and their duplexes with complementary oligodeoxynucleotides}, journal = {ORG. LETT.}, year = 2015, } @article{CTT100716360, author = {munefumi tokugawa and Kazuhei Kaneko and Masanori Saito and Takashi Kanamori and Yoshiaki Masaki and Akihiro Ohkubo and KOHJI SEIO and MITSUO SEKINE}, title = {Synthesis of responsive fluorescent Nucleobases 7-(Benzofuran-2-yl)-7- deazahypoxanthine and 7-(benzofuran-2-yl)-7-deazaguanine using cross-coupling reaction}, journal = {CHEM. LETT.}, year = 2015, } @article{CTT100716361, author = {Takashi Kanamori and Hiroki Ohzeki and Yoshiaki Masaki and Akihiro Ohkubo and MITSUO SEKINE and KOHJI SEIO}, title = {Controlling the fluorescence of benzofuran-modified uracil residues in oligonucleotides by triple-helix formation}, journal = {Chembiochem}, year = 2015, } @article{CTT100724912, author = {Yoshiaki Masaki and Takeshi Inde and Tetsuya Nagata and Jun Tanihata and Takashi Kanamori and Kohji Seio and Shin'ichi Takeda and Mitsuo Sekine}, title = {Enhancement of exon skipping in mdx52 mice by 2′-O-methyl-2-thioribothymidine incorporation into phosphorothioate oligonucleotides}, journal = {Med. Chem. Commun.}, year = 2014, } @article{CTT100785547, author = {Masaki Yoshiaki and Yamada Takeshi and Saneyoshi Hisao and Ohkubo Akihiro and Seio Kohji and Sekine Mitsuo}, title = {Synthesis and Exon-Skipping Activity of Chemically Modified RNAs}, journal = {Chemical Biology of Nucleic Acids: Fundamentals and Clinical Applications}, year = 2014, } @article{CTT100785023, author = {K. Yamada and Y. Masaki and H. Tsunoda and A. Ohkubo and K. Seio and M. Sekine}, title = {A new modified cytosine base capable of base pairing with guanine using four hydrogen bonds}, journal = {ORGANIC & BIOMOLECULAR CHEMISTRY}, year = 2014, } @article{CTT100785027, author = {Y. Masaki and R. Miyasaka and K. Hirai and T. Kanamori and H. Tsunoda and A. Ohkubo and K. Seio and M. Sekine}, title = {Properties of 5- and/or 2-modified 2 '-O-cyanoethyl uridine residue: 2 '-O-cyanoethyl-5-propynyl-2-thiouridine as an efficient duplex stabilizing component}, journal = {ORGANIC & BIOMOLECULAR CHEMISTRY}, year = 2014, } @article{CTT100785013, author = {T. Yamada and Y. Masaki and N. Okaniwa and T. Kanamori and A. Ohkubo and H. Tsunoda and K. Seio and M. Sekine}, title = {Synthesis and properties of oligonucleotides modified with 2 '-O-(2-carboxyethyl)nucleotides and their carbamoyl derivatives}, journal = {ORGANIC & BIOMOLECULAR CHEMISTRY}, year = 2014, } @article{CTT100785035, author = {Y. Iijima and S. Kojima and E. Kodama and S. Kurohagi and T. Kanamori and Y. Masaki and A. Ohkubo and M. Sekine and K. Seio}, title = {Modified oligodeoxynucleotide primers for reverse-transcription of target RNAs that can discriminate among length variants at the 3 '-terminus}, journal = {ORGANIC & BIOMOLECULAR CHEMISTRY}, year = 2013, } @article{CTT100785029, author = {K. Yamada and A. Ohkubo and Y. Esaka and T. Kanamori and Y. Masaki and K. Seio and M. Sekine}, title = {Base recognition of gap sites in DNA-DNA and DNA-RNA duplexes by short oligonucleotides}, journal = {BIOORGANIC & MEDICINAL CHEMISTRY LETTERS}, year = 2013, } @article{CTT100785033, author = {K. Seio and T. Kanamori and M. Tokugawa and H. Ohzeki and Y. Masaki and H. Tsunoda and A. Ohkubo and M. Sekine}, title = {Fluorescent properties of oligonucleotides doubly modified with an indole-fused cytosine analog and 2-aminopurine}, journal = {BIOORGANIC & MEDICINAL CHEMISTRY}, year = 2013, } @article{CTT100785548, author = {Yoshiaki Masaki}, title = {How were Ribonucleotides Synthesized in the Prebiotic Era?}, journal = {Journal of Synthetic Organic Chemistry Japan}, year = 2013, } @article{CTT100785042, author = {T. Kanamori and Y. Masaki and M. Mizuta and H. Tsunoda and A. Ohkubo and M. Sekine and K. Seio}, title = {DNA duplexes and triplex-forming oligodeoxynucleotides incorporating modified nucleosides forming stable and selective triplexes}, journal = {ORGANIC & BIOMOLECULAR CHEMISTRY}, year = 2012, } @article{CTT100785038, author = {K. Seio and S. Kurohagi and E. Kodama and Y. Masaki and H. Tsunoda and A. Ohkubo and M. Sekine}, title = {Short-RNA selective binding of oligonucleotides modified using adenosine and guanosine derivatives that possess cyclohexyl phosphates as substituents}, journal = {ORGANIC & BIOMOLECULAR CHEMISTRY}, year = 2012, } @article{CTT100785041, author = {Y. Masaki and R. Miyasaka and K. Hirai and H. Tsunoda and A. Ohkubo and K. Seio and M. Sekine}, title = {Prediction of the stability of modified RNA duplexes based on deformability analysis: Oligoribonucleotide derivatives modified with 2 '-o-cyanoethyl-5-propynyl-2-thiouridine as a promising component}, journal = {CHEMICAL COMMUNICATIONS}, year = 2012, } @article{CTT100785045, author = {H. Tsunoda and T. Kudo and Y. Masaki and A. Ohkubo and K. Seio and M. Sekine}, title = {Biochemical behavior of N-oxidized cytosine and adenine bases in DNA polymerase-mediated primer extension reactions}, journal = {NUCLEIC ACIDS RESEARCH}, year = 2011, } @article{CTT100785048, author = {A. Ohkubo and Y. Nishino and A. Yokouchi and Y. Ito and Y. Noma and Y. Kakishima and Y. Masaki and H. Tsunoda and K. Seio and M. Sekine}, title = {Stable triplex formation using the strong stacking effect of consecutive thionucleoside moieties}, journal = {CHEMICAL COMMUNICATIONS}, year = 2011, } @article{CTT100785062, author = {Y. Masaki and R. Miyasaka and A. Ohkubo and K. Seio and M. Sekine}, title = {Linear relationship between deformability and thermal stability of 2 '-O-modified RNA hetero duplexes}, journal = {JOURNAL OF PHYSICAL CHEMISTRY B}, year = 2010, } @article{CTT100785061, author = {Y. Masaki and A. Ohkubo and K. Seio and M. Sekine}, title = {Synthesis of 6-N-(benzothiazol-2-yl)deoxyadenosine and its exciton-coupled circular dichroism}, journal = {BIOORGANIC & MEDICINAL CHEMISTRY}, year = 2010, } @article{CTT100785549, author = {Seio Kohji and Miyazaki Kazuya and Kurohagi Sayako and Masaki Yoshiaki and Tsunoda Hirosuke and Ohkubo Akihiro and Sekine Mitsuo}, title = {Synthesis and properties of terminally modified oligonucleotides capable of short-RNA selective hybridization.}, journal = {Nucleic acids symposium series (2004)}, year = 2009, } @article{CTT100785507, author = {K. Seio and Y. Takaku and K. Miyazaki and S. Kurohagi and Y. Masaki and A. Ohkubo and M. Sekine}, title = {Synthesis of terminally modified oligonucleotides and their hybridization dependence on the size of the target RNAs}, journal = {ORGANIC & BIOMOLECULAR CHEMISTRY}, year = 2009, } @article{CTT100785544, author = {Saneyoshi Hisao and Okamoto Itaru and Masaki Yoshiaki and Ohkubo Akihiro and Seio Kohji and Mitsuo}, title = {Facile synthesis of 2 '-O-cyanoethyluridine by ring-opening reaction of 2,2 '-anhydrouridine with cyanoethyl trimethylsilyl ether in the presence of BF3 center dot Et2O}, journal = {Tetrahedron Letters}, year = 2007, } @inproceedings{CTT100917126, author = {立花茂載 and 大西里絵 and 正木慶昭 and 清尾康志}, title = {5´位を増炭したスルホンアミド骨格を有するチミジンダイマーの合成と物性評価}, booktitle = {}, year = 2024, } @inproceedings{CTT100917130, author = {島村大輝 and 有江嶺美 and 金山朱里 and 宮内彩 and 清尾康志 and 正木慶昭}, title = {細胞選択的送達を目指した糖リガンド修飾アンチセンス核酸の合成と性質}, booktitle = {}, year = 2024, } @inproceedings{CTT100917129, author = {瀧川駿太朗 and 友利貴人 and 植草宏哉 and 正木慶昭 and 清尾康志}, title = {2´水酸基にスルホンアミド修飾またはスルホネート修飾を有する5-メチルウリジン誘導体の合成および二重鎖形成能の評価}, booktitle = {}, year = 2024, } @inproceedings{CTT100917127, author = {田平彩乃 and 若月駿介 and 清尾 康志 and 正木 慶昭}, title = {置換基を導入した2´-O, 3´-C架橋アラビノフラノシルチミンを含むオリゴヌクレオチドの合成と性質}, booktitle = {}, year = 2024, } @inproceedings{CTT100917133, author = {宮地健人 and 羽生愛深 and 清尾康志 and 正木慶昭}, title = {7位にピリジル基を導入した7-デアザデオキシグアノシンを含むオリゴヌクレオチドの合成と性質}, booktitle = {}, year = 2024, } @inproceedings{CTT100917132, author = {鈴木雄大 and 須田雪音 and 井分彩乃 and 正木慶昭 and 清尾 康志}, title = {光架橋ビオチンリンカーを有するグアノシンテトラリン酸類似体の合成}, booktitle = {}, year = 2024, } @inproceedings{CTT100917124, author = {Masaki Y and Onishi Y and Seio K}, title = {Estimation of synthetic errors toward long DNA chemical synthesis}, booktitle = {}, year = 2024, } @inproceedings{CTT100917125, author = {Tabira A and Httori S and Seio K and Masaki Y}, title = {Extended phosphate backbone of ASO reveals importance of deoxyribose recognition by RNase H}, booktitle = {}, year = 2024, } @inproceedings{CTT100917122, author = {清尾康志 and 大西里絵 and 立花茂載 and 正木慶昭}, title = {スルホンアミド型バックボーンを導入したギャップマーの合成およびアンチセンス核酸としての性質}, booktitle = {}, year = 2023, } @inproceedings{CTT100917123, author = {田平彩乃 and 服部詩萌里 and 清尾康志 and 正木慶昭}, title = {メチレン基のリン酸バックボーンへの挿入がRNase Hによるミスマッチを含む二重差切断に与える影響}, booktitle = {}, year = 2023, } @inproceedings{CTT100895464, author = {Masaki Y and Onishi Y and Seio K}, title = {Systemic comparison of DNA chemical synthesis conditions by next-generation sequencing}, booktitle = {}, year = 2022, } @inproceedings{CTT100895469, author = {Tabira A and Masaki Y and Hattori S and Wakatsuki S and Seio K}, title = {Effects of inserting methylene group in the interaction of RNase H and ASO}, booktitle = {}, year = 2022, } @inproceedings{CTT100895468, author = {Tachibana S and Kanagawa T and Ohnishi R and Masaki Y and Seio K}, title = {Synthesis and the structural analysis of a cyclic sulfonamide thymidine derivative}, booktitle = {}, year = 2022, } @inproceedings{CTT100895467, author = {Yagata T and Masaki Y and Onishi Y and Seio K}, title = {Synthesis and property of alkoxytrityl type protecting group having reactive moiety}, booktitle = {}, year = 2022, } @inproceedings{CTT100895466, author = {Uekusa K and Tomori T and Koyama A and Masaki Y and Seio K}, title = {Synthesis of nucleoside and oligonucleotide derivatives incorporating 2’-O-sulfamoylpropyl or 2’-O-sulfamoylbutyl modifications}, booktitle = {}, year = 2022, } @inproceedings{CTT100895465, author = {Ohnishi R and Sekiya S and Edamura W and Tachibana S and Masaki Y and Seio K}, title = {Synthesis and structural analysis of sulfonamide linkage-containing oligonucleotides for the development of antisense nucleic acids}, booktitle = {}, year = 2022, } @inproceedings{CTT100895462, author = {植草宏哉 and 友利貴人 and 正木慶昭 and 清尾康志}, title = {2’-O-スルファモイルアルキル修飾を導入したオリゴヌクレオチドの合成と性質}, booktitle = {}, year = 2022, } @inproceedings{CTT100895461, author = {金川峻幸 and 小山彩 and 正木慶昭 and 清尾康志}, title = {塩基部修飾グアニン導入によるアンチセンス核酸の標的切断変化とオフターゲット抑制}, booktitle = {}, year = 2022, } @inproceedings{CTT100895460, author = {正木慶昭 and 田平彩乃 and 金川峻幸 and 若月駿介 and 服部詩萌里 and 小山彩 and 井上敦 and 清尾康志}, title = {RNase H依存型アンチセンス核酸の安全性向上に向けた化学修飾の開発}, booktitle = {}, year = 2022, } @inproceedings{CTT100895463, author = {金川峻幸 and 立花茂載 and 大西里絵 and 正木慶昭 and 清尾康志}, title = {スルホンアミド構造を有する環状チミジン誘導体の合成とその構造解析}, booktitle = {}, year = 2022, } @inproceedings{CTT100877689, author = {金川峻幸 and 立花茂載 and 大西里絵 and 正木慶昭 and 清尾康志}, title = {塩基部と5´位をスルホンアミド結合で架橋したチミジン誘導体の合成法の検討}, booktitle = {}, year = 2022, } @inproceedings{CTT100877690, author = {正木慶昭 and 田平彩乃 and 服部詩萌里 and 清尾康志}, title = {5´-デオキシ-5´-ヒドロキシメチルチミジン及び3´-デオキシ-3´-ヒドロキシメチルチミジンを含むリン酸骨格を伸長したオリゴヌクレオチドの合成と性質}, booktitle = {}, year = 2022, } @inproceedings{CTT100877684, author = {正木慶昭 and 矢形太一 and 清尾康志}, title = {次世代シーケンサーをもちいた化学合成DNAの副生成物解析}, booktitle = {}, year = 2022, } @inproceedings{CTT100877685, author = {井分彩乃 and 赤井恒 and 友利貴人 and 清尾康志 and 正木慶昭}, title = {リンカーを介して2´-水酸基にビオチンを有するグアノシンテトラリン酸誘導体の合成}, booktitle = {}, year = 2022, } @inproceedings{CTT100877686, author = {小山彩 and 友利貴人 and 江利川友紀 and 正木慶昭 and 清尾康志}, title = {2´カルバモイルエチルリンカーの脂溶性残基を導入したアンチセンスオリゴヌクレオチドの合成と特性評価}, booktitle = {}, year = 2022, } @inproceedings{CTT100877687, author = {大西里絵 and 関谷彰太 and 枝村亘 and 正木慶昭 and 清尾康志}, title = {スルホンアミド骨格を含む人工核酸の合成とアンチセンス活性の評価}, booktitle = {}, year = 2022, } @inproceedings{CTT100877688, author = {矢形太一 and 正木慶昭 and 清尾康志}, title = {末端アルキンを有するアルコキシトリチル型保護基の開発}, booktitle = {}, year = 2022, } @inproceedings{CTT100877683, author = {Tomori, T. and Kishimura T. and Uekusa K. and Koyama A. and Erikawa Y. and Masaki Y. and Seio K}, title = {Synthesis of oligonucleotides with lipophilic residues via 2´-O-carbamoylethyl linker for providing 3´-exonuclease resistance and duplex stability}, booktitle = {}, year = 2021, } @inproceedings{CTT100877682, author = {清尾康志 and 岸村智太 and 友利貴人 and 正木慶昭}, title = {2'位に種々のカルバモイルエチル基を有する人工核酸の合成とアンチセンス核酸としての性質}, booktitle = {}, year = 2021, } @inproceedings{CTT100856692, author = {正木慶昭 and 矢形太一 and 清尾康志}, title = {長鎖 DNA合成に向けたホスホロアミダイト法における副反応の解析}, booktitle = {}, year = 2021, } @inproceedings{CTT100856693, author = {岸村智太 and 植草宏哉 and 友利貴人 and 正木慶昭 and 清尾康志}, title = {2 ́-O-アルキルカルバモイルエチル型修飾を持つ人工核酸の合成および性質}, booktitle = {}, year = 2021, } @inproceedings{CTT100856694, author = {服部詩萌里 and 正木慶昭 and 清尾康志}, title = {リン酸骨格を伸長した5 ́-デオキシ-5 ́-ヒドロキシメチルチミジンを含むオリゴヌクレオチドの合成と性質}, booktitle = {}, year = 2021, } @inproceedings{CTT100856695, author = {赤井恒 and 杉山大樹 and 大野健太郎 and 友利貴人 and 正木慶昭 and 清尾康志}, title = {2'水酸基保護基にTBDMS基を用いた緊縮応答分子ppGppの化学合成法の開発}, booktitle = {}, year = 2021, } @inproceedings{CTT100856697, author = {清尾康志 and 大西里絵 and 関谷彰太 and 枝村亘 and 正木慶昭}, title = {スルホンアミド結合を含む人工核酸の合成と塩基対形成能}, booktitle = {}, year = 2021, } @inproceedings{CTT100856696, author = {若月駿介 and 井上敦 and 正木慶昭 and 清尾康志}, title = {2 ́-O,3 ́-C架橋型 [3.3.0]ビシクロアラビノフラノシルチミン誘導体を含むオリゴヌクレオチドの合成と性質}, booktitle = {}, year = 2021, } @inproceedings{CTT100836263, author = {若月駿介 and 井上敦 and 正木慶昭 and 清尾康志}, title = {2 ́-O,3 ́-C架橋型 [3.3.0] ピシクロアラビノフラノシルミチン誘導体の合成}, booktitle = {}, year = 2020, } @inproceedings{CTT100836265, author = {宮崎翔 and 正木慶昭 and 清尾康志}, title = {高圧条件下での2 ́,5 ́-ヌクレオチド残機を含んだRNA二重鎖の分子シミュレーション}, booktitle = {}, year = 2020, } @inproceedings{CTT100836260, author = {岸村智太 and 友利貴人 and 正木慶昭 and 清尾康志}, title = {2´位に種々のアルキルカルバモイルエチル修飾を持つ核酸の合成と二重鎖形成能}, booktitle = {}, year = 2020, } @inproceedings{CTT100836266, author = {Edamura W and Sekiya S and Masaki Y and Seio K}, title = {Conformation and properties of oligonucleotide with sulfonamide skeleton}, booktitle = {}, year = 2020, } @inproceedings{CTT100836261, author = {赤井恒 and 杉山大樹 and 大野健太郎 and 友利貴人 and 正木慶昭 and 清尾康志}, title = {ホスホロアミダイト化合物を用いた緊縮応答分子ppGppの効率的合成法}, booktitle = {}, year = 2020, } @inproceedings{CTT100836264, author = {山田悠司 and 竹下玲央 and 正木慶昭 and 清尾康志}, title = {光ケージされたデオキシシュードウリジンを含むDNA二重鎖および三重鎖構造の安定性の評価}, booktitle = {}, year = 2020, } @inproceedings{CTT100836257, author = {Miyazaki S and Masaki Y and Seio K}, title = {The conformational property of RNA duplex including 2 ́,5 ́-linkage under high pressure conditions}, booktitle = {}, year = 2019, } @inproceedings{CTT100836258, author = {Yamada Y and Takeshita L and Masaki Y and Seio K}, title = {Enzymatic synthesis and photo-deprotection of DNA incorporating photo-caged deoxypseudouridine}, booktitle = {}, year = 2019, } @inproceedings{CTT100836259, author = {Takeshita L and Iwake A and Tomori T and Masaki Y and Seio K}, title = {Enzymatic incorporation of 2'-O-alkylcarbamoyl-UTP for development of RNA aptamer}, booktitle = {}, year = 2019, } @inproceedings{CTT100811699, author = {正木慶昭 and 井上敦 and 入山友輔 and 金木達朗 and 中嶋宏之 and 清尾康志}, title = {化学修飾によるアンチセンス核酸のRNase H依存オフターゲット効果の抑制}, booktitle = {}, year = 2019, } @inproceedings{CTT100811700, author = {竹下玲央 and 井分彩乃 and 友利貴人 and 正木慶昭 and 清尾康志}, title = {2´-O-アルキルカルバモイル修飾UTPの合成と転写および逆転写反応への応用}, booktitle = {}, year = 2019, } @inproceedings{CTT100811698, author = {Y. Masaki and T. Inde and A. Maruyama and K. Seio}, title = {Tolerance of N2-heteroaryl modifications on guanine bases in G-quadruplex structure}, booktitle = {}, year = 2019, } @inproceedings{CTT100811694, author = {竹下玲央 and 井分彩乃 and 友利貴人 and 正木慶昭 and 清尾康志}, title = {アプタマー応用を志向した2´-O-カルバモイル型修飾を有するウリジン三リン酸の開発}, booktitle = {}, year = 2019, } @inproceedings{CTT100811693, author = {Y. Masaki and K. Yamamoto and Y. Yoshida and A. Maruyama and T. Tomori and Y. Iriyama and H. Nakajima and T. Kanaki and K. Seio}, title = {Synthesis and properties of 2'-O-modified oligonucleotides having carbamoylethyl linker}, booktitle = {}, year = 2019, } @inproceedings{CTT100811727, author = {Maruyama, A. and Yoshida, K. and Masaki, Y. and Seio, K.}, title = {Incorporation of peptide into 2 ́ position of oligonucleotide by Native Chemical Ligation}, booktitle = {}, year = 2019, } @inproceedings{CTT100811728, author = {杉山大樹 and 大野健太郎 and 正木慶昭 and 清尾康志}, title = {ホスホロアミダイト化合物を利用したグアノシンテトラリン酸の効率的合成法の開発}, booktitle = {}, year = 2019, } @inproceedings{CTT100811730, author = {山田悠司 and 竹下玲央 and 山田悠司 and 竹下玲央 and 正木慶昭 and 清尾康志}, title = {光ケージされた5-ヒドロキシメチルデオキシウリジンを含むDNAの酵素合成法}, booktitle = {}, year = 2019, } @inproceedings{CTT100811729, author = {井上敦 and 正木慶昭 and 清尾康志}, title = {2 ́,3 ́-糖部架橋型アラビノフラノシルチミン誘導体の効率的な合成研究}, booktitle = {}, year = 2019, } @inproceedings{CTT100811725, author = {Takeshita, L. and Masaki, Y. and Seio, K.}, title = {Synthesis and properties of photo-responsive DNA probes containing thioxanthone and nitrophenethyl group}, booktitle = {}, year = 2019, } @inproceedings{CTT100811726, author = {Kishimura, T. and Tomori, T. and Masaki, Y. and Seio, K.}, title = {Synthesis and properties of oligonucleotides having alkyl carbamoylethyl groups at 2 ́ position}, booktitle = {}, year = 2019, } @inproceedings{CTT100785115, author = {L. Takeshita and Y. Masaki and K. Seio}, title = {Synthesis and properties of photo-responsive DNA probes containing photo-cleavable protecting group and thioxanthone as a photo-sensitizer}, booktitle = {}, year = 2018, } @inproceedings{CTT100811724, author = {Maruyama A. and Inde T. and Masaki Y. and Seio K.}, title = {Synthesis of oligodeoxyribonucleotides containing 2-N-heteroarylguanine residues and their effect on G-quadruplex structure and stability}, booktitle = {}, year = 2018, } @inproceedings{CTT100785114, author = {Y. Masaki and K. Yamamoto and K. Yoshida and Y. Iriyama and H. Nakajima and T. Kanaki and T. Tomori and K. Seio}, title = {Application of 2'-O-carbamoylethyl-type modifications in antisense oligonucleotide}, booktitle = {}, year = 2018, } @inproceedings{CTT100785113, author = {Y. Masaki and T. Inde and A. Maruyama and K. Seio}, title = {Synthesis of oligodeoxyribonucleotides containing N2-heteroarylguanine residues and their properties in G-quadruplex structures}, booktitle = {}, year = 2018, } @inproceedings{CTT100811723, author = {岸村智太 and 吉田圭汰 and 友利貴人 and 正木慶昭 and 清尾康志}, title = {2´位にカルバモイルエチル型修飾を持つ核酸の合成と性質}, booktitle = {}, year = 2018, } @inproceedings{CTT100785112, author = {L. Takeshita and T. Shiozawa and D. Sugiyama and T. Tomori and Y. Masaki and K. Seio}, title = {A structure-activity relationship of incorporation of 2'-O-carbamoyl modified uridine triphosphate by RNA polymerase}, booktitle = {}, year = 2018, } @inproceedings{CTT100811722, author = {正木 慶昭 and 井上 敦 and 入山 友輔 and 金木 達朗 and 中嶋 宏之 and 清尾 康志}, title = {RNaseH依存型アンチセンス核酸への応用に向けた化学修飾核酸の開発}, booktitle = {}, year = 2018, } @inproceedings{CTT100785110, author = {丸山敦也 and 印出健志 and 正木慶昭 and 清尾康志}, title = {グアニン塩基部2位にヘテロアリール環修飾を有するオリゴヌクレオチドの合成と高次構造形成}, booktitle = {}, year = 2018, } @inproceedings{CTT100785111, author = {竹下玲央 and 山田悠司 and 正木慶昭 and 清尾康志}, title = {光ケージされたデオキシシュードウリジンを含むDNAの酵素合成法}, booktitle = {}, year = 2018, } @inproceedings{CTT100785109, author = {杉山大樹 and 塩澤貴史 and 大野健太郎 and 友利貴人 and 正木慶昭 and 清尾康志}, title = {ピロ亜リン酸による亜リン酸化反応を経由したヌクレオチド合成}, booktitle = {}, year = 2018, } @inproceedings{CTT100785108, author = {井上敦 and 正木慶昭 and 清尾康志}, title = {2',3'-糖部架橋型化学修飾核酸の合成}, booktitle = {}, year = 2018, } @inproceedings{CTT100785107, author = {関谷彰太 and 竹下玲央 and 正木慶昭 and 清尾康志}, title = {スルホンアミド骨格を有するオリゴヌクレオチドを鋳型に用いたDNAポリメラーゼ反応}, booktitle = {}, year = 2018, } @inproceedings{CTT100785106, author = {塩澤貴史 and 杉山大樹 and 友利貴人 and 正木慶昭 and 清尾康志}, title = {還元的リン化学種による生体小分子の亜リン酸化反応の検討}, booktitle = {}, year = 2018, } @inproceedings{CTT100785104, author = {L. TAKESHITA and Y. MASAKI and K. SEIO}, title = {Synthesis of DNA probes containing photo-sensitizer and caged molecule}, booktitle = {}, year = 2018, } @inproceedings{CTT100785103, author = {印出健志 and 正木慶昭 and 宮武佑弥 and 関根光雄 and 清尾康志}, title = {α-デオキシヌクレオシドを含むオリゴヌクレオチドのアンチパラレル型三重鎖形成能と塩基識別能}, booktitle = {}, year = 2018, } @inproceedings{CTT100785105, author = {岸村智太 and 吉田圭汰 and 阿野晃大 and 友利貴人 and 正木慶昭 and 清尾康志}, title = {2'水酸基に種々のカルバモイルエチル型修飾を持つ核酸の効率的合成と性質}, booktitle = {}, year = 2018, } @inproceedings{CTT100785101, author = {L. Takeshita and K. Ohno and K. Nagaoka and Y. Yamada and Y. Masaki and K. Seio}, title = {Photo-regulation of transcription by using enzymatically synthesized photo-caged DNA}, booktitle = {}, year = 2017, } @inproceedings{CTT100785100, author = {T. Inde and Y. Masaki and A. Maruyama and Y. Ito and N. Makio and Y. Miyatake and T. Tomori and M. Sekine and K. Seio}, title = {Synthesis of oligodeoxyribonucleotides containing 2-N-heteroarylguanine residues and their effect on higher-order structure stability}, booktitle = {}, year = 2017, } @inproceedings{CTT100785102, author = {D. Sugiyama and T. Shiozawa and K. Ohno and T. Tomori and Y. Masaki and K. Seio}, title = {Reaction of H-pyrophosphonic acid toward nucleosides, nucleotides and amino acids}, booktitle = {}, year = 2017, } @inproceedings{CTT100785098, author = {竹下玲央 and 大野健太郎 and 長岡健斗 and 山田悠司 and 正木慶昭 and 清尾康志}, title = {光分解性保護基を導入したヌクレオシド三リン酸の合成と転写反応の光制御への応用}, booktitle = {}, year = 2017, } @inproceedings{CTT100785099, author = {印出健志 and 丸山敦也 and 伊藤 優 and 牧尾直明 and 友利貴人 and 正木慶昭 and 関根光雄 and 清尾康志}, title = {2 位のアミノ基にヘテロアリール環を導入したデオキシグアノシン誘導体の合成と オリゴヌクレオチド中での性質評価}, booktitle = {}, year = 2017, } @inproceedings{CTT100785097, author = {関谷彰太 and 北川諒 and 竹下玲央 and 田胡信広 and 正木慶昭 and 清尾康志}, title = {スルホンアミド結合を有する人工核酸の新規合成と性質}, booktitle = {}, year = 2017, } @inproceedings{CTT100785096, author = {塩澤貴史 and 友利貴人 and 杉山大樹 and 金和平 and 正木慶昭 and 清尾康志}, title = {還元的リン化学種と生体小分子との反応の検討}, booktitle = {}, year = 2017, } @inproceedings{CTT100785093, author = {大野健太郎 and 竹下玲央 and 杉山大樹 and 正木慶昭 and 清尾康志}, title = {6-O-(2-ニトロベンジル)グアノシン三リン酸の合成と転写反応の光制御}, booktitle = {}, year = 2017, } @inproceedings{CTT100785092, author = {Yoshiaki Masaki and Mitsuo Sekine and KOHJI SEIO}, title = {Relationship between deformability of sugar-modified RNA duplexes and their melting temperatures}, booktitle = {}, year = 2017, } @inproceedings{CTT100785091, author = {正木 慶昭 and 宮坂 隆太 and 山本 恵士 and 吉田 圭汰 and 関根 光雄 and 清尾 康志}, title = {糖部修飾オリゴヌクレオチドの変形能解析と二重鎖融解温度の関係}, booktitle = {}, year = 2017, } @inproceedings{CTT100785089, author = {清尾康志 and 正木慶昭 and 山本恵士 and 印出健志 and 入山友輔 and 中島宏之 and 金木達朗 and 黒田雄介 and 古川賢 and 谷端 淳 and 永田哲也 and 武田伸一 and 関根 光雄}, title = {2’-水酸基にカルバモイルエチル型修飾を有する人工核酸を用いたアンチセンス核酸の開発}, booktitle = {}, year = 2017, } @inproceedings{CTT100722469, author = {正木 慶昭 and 吉田 圭汰 and 山本 恵士 and 関根 光雄 and 清尾 康志}, title = {糖部化学修飾RNA二重鎖の変形能と二重鎖融解温度の関係}, booktitle = {}, year = 2016, } @inproceedings{CTT100723580, author = {Takeshi Inde and Yoshiaki Masaki and Mitsuo Sekine and Kohji Seio}, title = {Base Pair Recognition of Alpha-deoxyribonucleosides with Unmodified Nucleobase and 8-Oxo-adenine in Antiparallel DNA Triplex}, booktitle = {}, year = 2016, } @inproceedings{CTT100723585, author = {Takahito Tomori and Kento Nagaoka and Yuya Miyatake and Yoshiaki Masaki and Mitsuo Sekine and Kohji seio}, title = {Synthesis and Enzymatic Properties of C-nucleoside Triphosphate Containing Pyridazin-3-one As a Uracil Analog}, booktitle = {}, year = 2016, } @inproceedings{CTT100723600, author = {Leo Takeshita and Kentaro Ohno and Yoshiaki Masaki and Mitsuo Sekine and Kohji Seio}, title = {Chemical and Enzymatic Synthesis of Photo-caged DNA containing N1-Nitrobenzyl-2´-deoxypseudouridine for UV Dependent Regulation of Transcription}, booktitle = {}, year = 2016, } @inproceedings{CTT100723931, author = {塩澤 貴史 and 正木 慶昭 and 金子 和平 and チャンガディブラタ ヤン クリスティアン and 徳川 宗史 and 清尾 康志}, title = {一本鎖結合タンパク質とDNAの相互作用を検出するための(7-ベンゾフラン-2-イル)-7-デアザ-2´-デオキシグアノシンを有する蛍光プローブ}, booktitle = {}, year = 2016, } @inproceedings{CTT100722445, author = {Yoshiaki Masaki and Ryuta Miyasaka and Keishi Yamamoto and Keita Yoshida and Akihiro Ohkubo and Mitsuo Sekine and Kohji Seio}, title = {Deformability analysis of chemically modified RNA and its applicability for estimation of RNA duplex stability}, booktitle = {}, year = 2016, } @inproceedings{CTT100724887, author = {Hiroya Asami and Munefumi Tokugawa and Yoshiaki Masaki and Eric Gloaguen and Kohji Seio and Mitsuo Sekine and Michel Mons}, title = {An Effective Molecular Model for Nanosecond Laser Spectroscopy of Short-lived Nucleobase: Application to Anharmonic Vibrational Analysis in the Mid-IR Region}, booktitle = {}, year = 2016, } @inproceedings{CTT100724394, author = {山本 恵士 and 正木 慶昭 and 吉田圭汰 and 入山 友輔 and 中嶋 宏之 and 金木 達朗 and 関根 光雄 and 清尾 康志}, title = {2-(N-エチルカルバモイル)エチル構造を有する糖部修飾核酸の合成と性質}, booktitle = {}, year = 2016, } @inproceedings{CTT100724396, author = {友利 貴人 and 長岡 健斗 and 宮武 佑弥 and 正木 慶昭 and 関根 光雄 and 清尾 康志}, title = {ピリダジン-3-オンを核酸塩基部に有する/C/ヌクレオシドの合成と性質}, booktitle = {}, year = 2016, } @inproceedings{CTT100724400, author = {竹下 玲央 and 大野 健太郎 and 正木 慶昭 and 関根 光雄 and 清尾 康志}, title = {DNA-タンパク質相互作用の光制御をめざした光ケージされたデオキシシュードウリジンを含む核酸の合成および性質}, booktitle = {}, year = 2016, } @inproceedings{CTT100724410, author = {宮村 大地 and 金森 功吏 and 正木 慶昭 and 関根 光雄 and 清尾 康志}, title = {塩基部5位に3-メチルベンゾフラン誘導体を導入した2'-デオキシウリジンの合成と蛍光特性}, booktitle = {}, year = 2016, } @inproceedings{CTT100724884, author = {岸村智太 and 印出健志 and 正木慶昭 and 関根光雄 and 清尾康志}, title = {アンチセンス核酸の5´末端に糖を修飾するためのリンカーの設計と合成}, booktitle = {}, year = 2016, } @inproceedings{CTT100724885, author = {小田雄貴 and 伊藤比佑吾 and 金森功吏 and 大窪章寛 and 正木慶昭 and 関根光雄 and 清尾康志}, title = {塩基性条件下不安定なヌクレオシド三リン酸の新規合成法の開発}, booktitle = {}, year = 2016, } @inproceedings{CTT100724389, author = {北川 諒 and 田胡 信広 and 関谷 彰太 and 正木 慶昭 and 関根 光雄 and 清尾 康志}, title = {スルホンアミド骨格を有するヌクレオシド誘導体の合成と性質}, booktitle = {}, year = 2016, } @inproceedings{CTT100724896, author = {Yoshiaki Masaki and Keishi Yamamoto and Takeshi Inde and Tetsuya Nagata and Jun Tanihata and Yusuke Iriyama and Shinishi Takeda and Mitsuo Sekine and KOHJI SEIO}, title = {Enhancement of exon skipping efficiency by using antisense oligonucleotides containing 2-thiothymidine derivatives}, booktitle = {}, year = 2015, } @inproceedings{CTT100723567, author = {Yoshiaki Masaki and Keishi Yamamoto and Takeshi Inde and Tetsuya Nagata and Jun Tanihata and Yusuke Iriyama and Shin'ichi Takeda and Kohji Seio and Mitsuo Sekine}, title = {Enhancement of exon skipping by 2´-O-(N-methylcarbamoyl)ethyl (MCE) and/or nucleobase modified nucleosides incorporation into phosphorothioate oligonucleotides}, booktitle = {}, year = 2015, } @inproceedings{CTT100723956, author = {Yu Ito and Takashi Kanamori and Yoshiaki Masaki and Akihiro Ohkubo and Kohji Seio and Mitsuo Sekine}, title = {Synthesis of deoxyuridine derivatives modified with 2,4-diaminopyrimidine moiety for the development of high affinity triplex forming oligonucleotides}, booktitle = {}, year = 2015, } @inproceedings{CTT100723963, author = {Kentaro Ohno and Leo Takeshita and Yoshihiro Iijima and Takashi Kanamori and Yoshiaki Masaki and Mitsuo Sekine and Kohji Seio}, title = {Synthesis of oligonucleotides containing photo-caged 2´ -deoxypseudouridine for the regulation of DNA-protein interaction}, booktitle = {}, year = 2015, } @inproceedings{CTT100723961, author = {Ayano Yamazaki and Kei Yamaguchi and Takashi Kanamori and Yoshiaki Masaki and Mitsuo Sekine and Kohji Seio}, title = {Synthesis of oligodeoxynucleotides containing 2´-deoxy-pseudoisocytidine for the development of chemically modified DNA duplexes and triplexes}, booktitle = {}, year = 2015, } @inproceedings{CTT100724882, author = {田胡信広 and 北川諒 and Adam Kotolik and Nathaniel E. Clark and Eric J. Montemayor and P. John Hart and 正木 慶昭 and 金森 功吏 and 関根 光雄 and 清尾 康志 and Masad J. Damha}, title = {5'-アミノグアノシンを分岐部位に導入した2'-5'修飾分岐RNAの合成と性質}, booktitle = {}, year = 2015, } @inproceedings{CTT100724868, author = {大野 健太郎 and 正木 慶昭 and 金森 功吏 and 関根 光雄 and 清尾 康志}, title = {光ケージヌクレオシド三リン酸の合成と性質}, booktitle = {}, year = 2015, } @inproceedings{CTT100724858, author = {山本 恵士 and 正木 慶昭 and 石井 陽大 and 印出 健志 and 金森 功吏 and 関根 光雄 and 清尾 康志}, title = {2'-O-メチルカルバモイルエチル修飾2-チオリボチミジンを含むオリゴヌクレオチドの合成と性質}, booktitle = {}, year = 2015, } @misc{CTT100805258, author = {正木慶昭}, title = {接触消光を利用した新たな細胞内RNAのイメージング}, year = 2014, } @misc{CTT100926884, author = {正木慶昭}, title = {安全性の高い核酸配列の設計法}, howpublished = {公開特許}, year = 2024, month = {}, note = {特願2023-002073(2023/01/11), 特開2024-098537(2024/07/24)} } @misc{CTT100907829, author = {清尾康志 and 正木慶昭 and 友利貴人 and 植草宏哉}, title = {2’位にアミノスルホニルアルコキシ基を有する新規人工核酸}, howpublished = {公開特許}, year = 2023, month = {}, note = {特願2022-031303(2022/03/01), 特開2023-127483(2023/09/13)} } @misc{CTT100907817, author = {清尾康志 and 正木慶昭 and 金川峻幸 and 小山彩}, title = {塩基部修飾ヌクレオシドを含む新規アンチセンス核酸}, howpublished = {公開特許}, year = 2023, month = {}, note = {特願2022-031307(2022/03/01), 特開2023-127484(2023/09/13)} } @misc{CTT100885378, author = {正木慶昭}, title = {非天然塩基を利用した長鎖DNA合成}, howpublished = {公開特許}, year = 2022, month = {}, note = {PCT/JP2022/012843(2022/03/18), WO 2022/220019(2022/10/20)} } @misc{CTT100846525, author = {清尾康志 and 正木慶昭 and 山本恵士 and 吉田圭汰 and 入山 友輔 and 中嶋 宏之 and 金木 達朗}, title = {人工ヌクレオシド及び人工ヌクレオチド並びに人工オリゴヌクレオチド}, howpublished = {登録特許}, year = 2022, month = {}, note = {特願2020-202186(2020/12/04), 特開2021-046433(2021/03/25), 特許第7085739号(2022/06/09)} } @misc{CTT100869598, author = {清尾康志 and 正木慶昭 and 友利貴人}, title = {アンチセンス核酸の毒性を軽減する方法}, howpublished = {公開特許}, year = 2021, month = {}, note = {PCT/JP2020/044370(2020/11/27), WO 2021/107143(2021/06/03)} } @misc{CTT100846537, author = {正木慶昭 and 清尾康志 and 井上敦 and 入山友輔 and 金木達朗 and 中嶋宏之}, title = {毒性が低減されたアンチセンスオリゴヌクレオチド}, howpublished = {公開特許}, year = 2021, month = {}, note = {特願2020-507884(2019/03/20), 再表/2019/182037(2021/03/11)} } @misc{CTT100845884, author = {清尾康志 and 正木慶昭 and 大野健太郎 and 友利貴人}, title = {グアノシン-3’,5’-ビスジホスフェートの製造方法及びその製造中間体}, howpublished = {登録特許}, year = 2023, month = {}, note = {特願2019-571182(2019/02/08), 再表2019/156240(2021/01/28), 特許第7205914号(2023/01/06)} } @misc{CTT100845919, author = {清尾康志 and 正木慶昭}, title = {スルホンアミド骨格をもつオリゴヌクレオチドを鋳型として用いたDNA複製法}, howpublished = {公開特許}, year = 2021, month = {}, note = {特願2019-568531(2018/02/02), 再表2019/150564(2021/02/04)} } @misc{CTT100793185, author = {清尾康志 and 正木慶昭 and 山本恵士 and 吉田圭汰 and 入山 友輔  and 中嶋 宏之 and 金木 達朗 }, title = {人工ヌクレオシド及び人工ヌクレオチド並びに人工オリゴヌクレオチド}, howpublished = {登録特許}, year = 2021, month = {}, note = {特願2018-500218(2017/02/17), 再表2017/142054(2018/12/06), 特許第6853537号(2021/03/16)} } @misc{CTT100758860, author = {清尾康志 and 正木慶昭 and 島崎 猛夫 and 山本 聡子}, title = {アンチセンスオリゴ核酸化合物およびその配列決定法}, howpublished = {公開特許}, year = 2017, month = {}, note = {特願2016-070202(2016/03/31), 特開2017-176074(2017/10/05)} } @misc{CTT100690777, author = {関根光雄 and 清尾康志 and 大窪章寛 and 角田浩佑 and 正木慶昭 and 金森功吏 and 山田 希 and 山崎一史 and 伊藤比祐吾}, title = {2'-0-カルバモイル修飾ヌクレオシド三リン酸}, howpublished = {登録特許}, year = 2017, month = {}, note = {特願2013-152578(2013/07/23), 特開2015-020994(2015/02/02), 特許第6261027号(2017/12/22)} }