論文

• Y. Nakamura, K. Okumura, T. Ota, T. Sato, T. Ishikawa, S. Mineo, H. Maejima, 藤本 善徳, 池川 信夫. コレステロール吸収阻害剤としてのスタノールについて-海藻のステロール成分の研究-, 日本臨床代替医学会誌, Vol. 73, No. 1/2, pp. 200-206, 2004.
• K. Okumura, Y. Nakamura, S. Takeuchi, I. Kato, Y. Fujimoto, N. Ikekawa. Formal total synthesis of squalamine from desmosterol, Chem. Pharm. Bull., Vol. 51, No. 10, pp. 1177-1182, Oct. 2003.
• E. Zeeck, J. D. Hardege, A. Willing, N. Ikekawa, Y. Fujimoto. Sex pheromones in marine polychaetes: steroids from ripe Nereis succinea, Steroids, Vol. 59, No. 5, pp. 341-344, May 1994.
• J. Mungarulire, R. M. Munabu, C. Murasaki, T. Eguchi, Y. Fujimoto, K. Kakinuma, K. Kobayashi, M. Uramoto, N. Ikekawa. A novel steroidal saponin, pogosterol from Vernonia pogosperma, Chem. Pharm. Bull., Vol. 41, No. 2, pp. 411-413, Feb. 1993.
• M. Tomita, J. Togami, Y. Fujimoto, N. Ikekawa, R. Taguchi, H. Ikezawa. Effect of 22R-hydroxycholesterol on the action of sphingomyelinase from Bacillus cereus toward bovine erythrocytes, Toxicon, Vol. 30, No. 8, pp. 801-813, Aug. 1992.
• Y. Fujimoto, M. Nagakari, Y. Ikuina, N. Ikekawa, K. Kakinuma. Stereochemistry of the hydrogen addition to C-25 of desmosterol by sterol-Δ²⁴-reductase of the silkworm, Bombyx mori, J. Chem. Soc., Chem. Commun., No. 10, pp. 688-689, 1991.
• Y. Fujimoto, T. Eguchi, C. Murasaki, Y. Ohashi, K. Kakinuma, H. Takagaki, M. Abe, K. Inazawa, K. Yamazaki, N. Ikekawa, O. Yoshikawa, T. Ikekawa. Studies on the structure and stereochemistry of cytotoxic furanonaphthoquinones from Tabebuia impetiginosa: 5- and 8-hydroxy-2-(1-hydroxyethyl)naphtho[2,3-b]furan-4,9-diones, J. Chem. Soc., Perkin Trans. 1, No. 10, pp. 2323-2327, 1991.
• K. Kakinuma, M. Yamagishi, Y. Fujimoto, N. Ikekawa, T. Oshima. Biosynthetic mechanism of sn-2,3-di-O-phytanylglycerol, core membrane lipid of the Archaebacterium Halobacterium halobium, J. Am. Chem. Soc., Vol. 112, No. 7, pp. 2740-2745, Mar. 1990.
• Y. Fujimoto, Y. Ikuina, Y. Kanzawa, M. Nagakari, K. Kakinuma, N. Ikekawa. Mechanism of BF₃・etherate-catalyzed rearrangement of fucosterol epoxide, Heterocycles, Vol. 30, No. 1, pp. 275-278, Jan. 1990.
• Y. Fujimoto, C. Murasaki, K. Kakinuma, T. Eguchi, N. Ikekawa, M. Furuya, K. Hirayama, T. Ikekawa, M. Sahai, Y. K. Gupta, A. B. Ray. Squamostatin-A: Unprecedented bis-tetrahydrofuran acetogenin from Annona squamosa, Tetrahedron Lett., Vol. 31, No. 4, pp. 535-538, 1990.
• Y. Fujimoto, Y. Ikuina, M. Nagakari, K. Kakinuma, N. Ikekawa. C-25 Prochirality in the fragmentation reaction catalyzed by fucosterol epoxide lyase from the silkworm, Bombyx mori, J. Chem. Soc., Perkin Trans. 1, No. 7, pp. 2041-2046, 1990.
• Y. Fujimoto, K. Kakinuma, T. Eguchi, N. Ikekawa, N. Hirayama, A. Mbarushimana, D. Ntahomvukiye. 12,15-Dihydroxylabda-8(17),13-dien-19-oic acid from Guizotia scabra, Phytochemistry, Vol. 29, No. 1, pp. 319-321, 1990.
• N. Ikekawa, Y. Fujimoto, S. Kadota, T. Kikuchi. Effective separation of sterol C-24 epimers, Journal of Chromatography, Vol. 468, pp. 91-98, May 1989.
• Y. Fujimoto, M. Hiramoto, K. Kakinuma, N. Ikekawa. Elimination of C-6-hydrogen during the formation of ecdysteroids from cholesterol in Locusta migratoria ovaries, Steroids, Vol. 53, No. 3-5, pp. 477-485, Mar. 1989.
• Y. Fujimoto, Y. Ikuina, Y. Kanzawa, K. Kakinuma, N. Ikekawa. Mechanism of the boron trifluoride etherate-catalyzed rearrangement of an acyclic trisubstituted epoxide to a carbonyl compound, J. Chem. Soc., Chem. Commun., No. 16, pp. 1107-1109, 1989.
• M. Kimura, S. Sakurai, T. Nakamachi, M. Nariki, S. Niimi, T. Ohtaki, Y. Fujimoto, F. Hata, N. Ikekawa. Qualitative and quantitative analysis of juvenile hormone in the larvae of the silkworm, Bombix mori, Zoological Science, Vol. 6, No. 1, pp. 121-127, 1989.
• E. Ohnishi, M. Hiramoto, Y. Fujimoto, K. Kakinuma, N. Ikekawa. Isolation and identification of major ecdysteroid conjugates from the ovaries of Bombyx mori, Insect Biochemistry, Vol. 19, No. 1, pp. 95-101, 1989.
• Y. Fujimoto, T. Eguchi, K. Kakinuma, N. Ikekawa, M. Sahai, Y. K. Gupta. Squamocin, a new cytotoxic bis-tetrahydrofuran containing acetogenin from Annona squamosa, Chem. Pharm. Bull., Vol. 36, No. 12, pp. 4802-4806, Dec. 1988.
• K. Gamoh, T. Kitsuwa, S. Takatsuto, Y. Fujimoto, N. Ikekawa. Determination of trace brassinosteroids by high-performance liquid chromatography, Analytical Sciences, Vol. 4, No. 5, pp. 533-535, Oct. 1988.
• T. Eguchi, Y. Fujimoto, K. Kakinuma, N. Ikekawa, M. Sahai, M. P. Verma, Y. K. Gupta. 23-Hydroxyphysalolactone, a new withanolide with a 23-hydroxyl group from Physalis peruviana (Solanaceae), Chem. Pharm. Bull., Vol. 36, No. 8, pp. 2897-2901, Aug. 1988.
• K. Nakamura, T. Yamada, Y. Fujimoto, K. Kakinuma, N. Ikekawa. Synthesis of 3β,6α-dihydroxycholesta-9(11),17(20),24-trien-23-one, the aglycon of acrosome reaction-inducing steroidal saponin Co-ARIS II, Chem. Pharm. Bull., Vol. 36, No. 8, pp. 2808-2812, Aug. 1988.
• M. Hiramoto, Y. Fujimoto, K. Kakinuma, N. Ikekawa, E. Ohnishi. Ecdysteroid conjugates in the ovaries of the silkworm, Bombyx mori: 3-Phosphates of 2,22-dideoxy-20-hydroxy-ecdysone and of bombycosterol, Experientia, Vol. 44, No. 7, pp. 623-625, July 1988.
• K. Kakinuma, M. Yamaguchi, Y. Fujimoto, T. Oshima, N. Ikekawa. Stereochemistry of the biosynthesis of sn-2,3-O-diphytanyl glycerol, membrane lipid of archaebacteria Halobacterium halobium, J. Am. Chem. Soc., Vol. 110, No. 14, pp. 4861-4863, July 1988.
• M. Tsubaki, A. Hiwatashi, Y. Ichikawa, Y. Fujimoto, N. Ikekawa, H. Hori. Electron paramagnetic resonance study of ferrous cytochrome P-450_scc-nitric oxide complexes: effects of 20(R),22(R)-dihydroxycholesterol and reduced adrenodoxin, Biochemistry, Vol. 27, No. 13, pp. 4856-4862, June 1988.
• N. Ikekawa, F. Nishiyama, Y. Fujimoto. Identification of 24-epibrassinolide in bee pollen of the broad bean, Vicia faba L, Chem. Pharm. Bull., Vol. 36, No. 1, pp. 405-407, Jan. 1988.
• Y. Fujimoto, T. Kinoshita, I. Ohya, K. Kakinuma, N. Ikekawa, M. Morisaki. Non-stereoselective conversion of the four diastereomers at the C-24 and C-25 positions of 3α,7α,12α,24-tetrahydroxy-5β-cholestan 26-oic acid into cholic acid, Chem. Pharm. Bull., Vol. 36, No. 1, pp. 142-145, Jan. 1988.
• T. Kinoshita, M. Miyata, S. M. Ismail, Y. Fujimoto, K. Kakinuma, N. Ikekawa, M. Morisaki. Synthesis and determination of stereochemistry of four diastereoisomers at the C-24 and C-25 position of 3α,7α,12α,24-tetrahydroxy-5β-cholestan-26-oic acid, Chem. Pharm. Bull., Vol. 36, No. 1, pp. 134-141, Jan. 1988.
• I. Nishiyama, T. Matsui, Y. Fujimoto, N. Ikekawa, M. Hoshi. Correlation between the molecular structure and the biological activity of Co-ARIS, a cofactor for acrosome reaction-inducing substance, Develop. Growth Differ., Vol. 29, No. 2, pp. 171-176, Apr. 1987.
• Y. Fujimoto, T. Yamada, N. Ikekawa, I. Nishiyama, T. Matsui, M. Hoshi. Structure of acrosome reaction-inducing steroidal saponins from the egg jelly of the starfish, Asterias amurensis, Chem. Pharm. Bull., Vol. 35, No. 5, pp. 1829-1832, 1987.
• Y. Fujimoto, T. Kinoshita, N. Ikekawa, J. Mungarulire. Sesquiterpene lactones from Gutenbergia cordifolia, Phytochemistry, Vol. 26, No. 9, pp. 2593-2595, 1987.
• T. Mimura, M. Okabe, M. Satake, T. Nakanishi, A. Inada, Y. Fujimoto, F. Hata, Y. Matsumura, N. Ikekawa. Fatty acids and sterols of the tunicate Salpa thompsoni from the Antarctic ocean: chemical composition and hemolytic activity, Chem. Pharm. Bull., Vol. 34, No. 11, pp. 4562-4568, Nov. 1986.
• S. Sakurai, N. Yoneyama, Y. Fujimoto, F. Hata, N. Ikekawa. 7-Dehydrosterols in prothoracic glands of the silkworm, Bombyx mori, Experientia, Vol. 42, No. 9, pp. 1034-1036, Sept. 1986.
• A. Morigiwa, K. Kitabatake, Y. Fujimoto, N. Ikekawa. Angiotensin converting enzyme-inhibitory triterpenes from Ganoderma lucidum, Chem. Pharm. Bull., Vol. 34, No. 7, pp. 3025-3028, July 1986.
• M. Ohtsuka, Y. Fujimoto, N. Ikekawa. Steroidal inhibitors of microbial degradation of sterol side chains, Chem. Pharm. Bull., Vol. 34, No. 7, pp. 2780-2785, July 1986.
• Y. Fujimoto, N. Ikekawa, M. Ogiso, E. Ohnishi. Characterization of 17β-estradiol 3-(β-D-glucopyranoside) and 17-(α-D-glucopyranoside) as the metabolites of 17β-estradiol in the cultured ovaries of the silkworm, Bombyx mori, Experientia, Vol. 42, No. 5, pp. 567-568, May 1986.
• H. Iwadate, K. Gamoh, Y. Fujimoto, N. Ikekawa. Stereochemistry in the hydrogenation of steroidal (22R)- and (22S)-Δ²⁴-26,22-lactones, Chem. Pharm. Bull., Vol. 34, No. 5, pp. 2061-2065, May 1986.
• M. Ogiso, Y. Fujimoto, N. Ikekawa, E. Ohnishi. Glucosidation of 17β-estradiol in the cultured ovaries of the silkworm, Bombyx mori, General and Comparative Endocrinology, Vol. 61, No. 3, pp. 393-401, Mar. 1986.
• E. Ohnishi, M. Ogiso, K. Wakabayashi, Y. Fujimoto, N. Ikekawa. Identification of estradiol in the ovaries of the silkworm, Bombyx mori, Gen. Comp. Endocrinol., Vol. 60, No. 1, pp. 35-38, Oct. 1985.
• Y. Fujimoto, T. Yamada, N. Ikekawa. Pyridine-induced deshielding of 4-methylene protons for the determinaion of carbon-6 stereochemistry of sterols having a 5α,6-diol moiety. Revision of the carbon-6 stereochemistry of marine sterol isolated from a sponge, Dysidea sp., Chem. Pharm. Bull., Vol. 33, No. 8, pp. 3129-3133, Aug. 1985.
• Y. Fujimoto, S. Miyasaka, T. Ikeda, N. Ikekawa, E. Ohnishi, T. Mizuno, K. Watanabe. An unusual ecdysteroid, (20S)-cholesta-7,14-diene-3β,5α,6α,20,25-pentaol (bombycosterol) from the ovaries of the silkworm, Bombyx mori, J. Chem. Soc., Chem. Commun., No. 1, pp. 10-12, 1985.
• Y. Fujimoto, H. Iwadate, N. Ikekawa, K. Kihira, T. Hoshita. Structure of the steroidal lactone is isolated from turtle bile: (22S,25R)-3α,7α,12α-trihydroxy-5β-cholestano-26-22-lactone, J. Chem. Soc., Perkin Trans. 1, No. 12, pp. 2701-2704, 1985.
• Y. Fujimoto, M. Ohhana, T. Terasawa, N. Ikekawa. Stereocontrolled synthesis of petrosterol, Tetrahedron Lett., Vol. 26, No. 27, pp. 3239-3242, 1985.
• Y. Fujimoto, H. Iwadate, N. Ikekawa. Preparation of optically active 2,2'-dihydroxy-1,1'-binaphthyl via microbial resolution of the corresponding racemic diester, J. Chem. Soc., Chem. Commun., No. 19, pp. 1333-1334, 1985.
• Y. Fujimoto, M. Kimura, F. A. M. Khalifa, N. Ikekawa. Side chain structural requirement for utilization of sterols by the silkworm for growth and development. Non-stereoselective utilization of the 24-stereoisomeric pairs of 24-alkylsterols, Chem. Pharm. Bull., Vol. 32, No. 11, pp. 4372-4381, Nov. 1984.
• T. Kikuchi, S. Kadota, T. Shima, N. Ikekawa, Y. Fujimoto. Effective separation of sterol C-24 epimers by reversed-phase high performance liquid chromatography, Chem. Pharm. Bull., Vol. 32, No. 9, pp. 3779-3782, Sept. 1984.
• Y. Fujimoto, M. Kimura, T. Terasawa, Khalifa Fathy A. M., N. Ikekawa. Stereocontrolled synthesis and determination of the C-24 and C-25 stereochemistry of glaucasterol, Tetrahedron Lett., Vol. 25, No. 17, pp. 1805-1808, 1984.
• Y. Fujimoto, M. Kimura, A. Takasu, F. A. M. Khalifa, M. Morisaki, N. Ikekawa. Mechanism of stigmasterol dealkylation in insect, Tetrahedron Lett., Vol. 25, No. 14, pp. 1501-1504, 1984.
• T. Terasawa, Y. Hirano, Y. Fujimoto, N. Ikekawa. Stereocontrolled syntehsis of gorgosterol, J. Chem. Soc., Chem. Commun., No. 20, pp. 1180-1182, 1983.
• S. Maruyama, Y. Fujimoto, M. Morisaki, N. Ikekawa. Mechanism of campesterol demethylation in insect, Tetrahedron Lett., Vol. 23, No. 16, pp. 1701-1704, 1982.
• H. Kojima, T. Yoshida, T. Ikeda, Y. Fujimoto, N. Ikekawa. Distribution of administered squalene into mouse body, Igaku to Yakugaku, Vol. 8, pp. 533, 1982.
• S. Sato, A. Akaiwa, Y. Fujimoto, M. Ishiguro, N. Ikekawa. Synthesis of demethylgorgosterol and its stereoisomers, Chem. Pharm. Bull., Vol. 29, No. 2, pp. 406-415, Feb. 1981.
• Y. Fujimoto, M. Morisaki, N. Ikekawa. Stereochemical importance of fucosterol epoxide in the conversion of sitosterol into cholesterol in the silkworm, Bombyx mori, Biochemistry, Vol. 19, No. 6, pp. 1065-1069, Mar. 1980.
• Y. Fujimoto, K. Murakami, N. Ikekawa. Synthesis of (24R,28R)- and (24S,28S)-fucosterol epoxides. Revision of C-24,28 configurations, J. Org. Chem., Vol. 45, No. 4, pp. 566-569, Feb. 1980.
• N. Ikekawa, Y. Fujimoto, A. Takasu, M. Morisaki. Isolation of fucosterol epoxide from larvae of the silkworm, Bombyx mori, J. Chem. Soc., Chem. Commun., No. 15, pp. 709b-711, 1980.
• N. Ikekawa, Y. Fujimoto, M. Ishiguro, S. Suwa, Y. Hirayama, H. Mizunuma. C26 Sterol in a human urine, Science, Vol. 204, No. 4398, pp. 1223-1224, June 1979.
• Y. Fujimoto, N. Ikekawa. Convenient preparation of the C-24 stereoisomers of 24-ethyl- and 24-methylcholesterols, J. Org. Chem., Vol. 44, No. 6, pp. 1011-1012, May 1979.
• N. Koizumi, Y. Fujimoto, T. Toru, N. Ikekawa. Part 49. Carbon-13 nuclear magnetic resonance of 24-substituted steroids, Chem. Pharm. Bull., Vol. 27, No. 1, pp. 38-42, Jan. 1979.
• N. Ikekawa, Y. Fujimoto, M. Ishiguro, S. Suwa, Y. Hirayama, H. Mizunuma. Identification of a C26-sterol in urine and serum of patient with congenital adrenal hyperplasia, Proc. Japan Acad., Ser. B, Vol. 55, No. 5, pp. 252-257, 1979.
• M. Ishiguro, A. Akaiwa, Y. Fujimoto, S. Sato, N. Ikekawa. Stereoselective synthesis of demethylgorgosterol, Tetrahedron Lett., Vol. 20, No. 9, pp. 763-766, 1979.
• Y. Fujimoto, N. Ikekawa. Hydrogenolysis of allylic alcohols with a mixed hydride reagent of lithium aluminum hydride-titanium tetrachloride, Chem. Pharm. Bull., Vol. 24, No. 4, pp. 825-828, Apr. 1976.
• N. Awata, M. Morisaki, Y. Fujimoto, N. Ikekawa. Inhibitory effects of steroidal allenes on growth, development, and steroid metabolism of the silkworm, Bombyx mori, J. Insect Physiol., Vol. 22, No. 3, pp. 403-408, 1976.
• Y. Fujimoto, M. Morisaki, N. Ikekawa. Studies on steroids. Part XXIX. Synthesis of allenic analogs of fucosterol and desmosterol, J. Chem. Soc., Perkin Trans. 1, No. 22, pp. 2302-2307, 1975.
• M. Morisaki, N. Awata, Y. Fujimoto, N. Ikekawa. Steroidal allenes as inhibitors of sterol biosynthesis, J. Chem. Soc., Chem. Commun., No. 9, pp. 362-363, 1975.
• Y. Fujimoto, M. Morisaki, N. Ikekawa, Y. Horie, S. Nakasone. Synthesis of 24,28-iminofucosterol and its inhibitory effects on growth and steroid metabolism in the silkworm, Bombyx mori, Steroids, Vol. 24, No. 3, pp. 367-375, Sept. 1974.
• Y. Fujimoto, N. Awata, M. Morisaki, N. Ikekawa. Migration of C-25 hydrogen of sitosterol to C-24 during conversion to desmosterol in the silkworm, Bombyx mori, Tetrahedron Lett., Vol. 15, No. 49/50, pp. 4335-4338, 1974.

著書

• 池川 信夫, 藤本 善徳. 創薬化学の基礎となる先導物質の合成法(共著), 廣川書店, 廣川書店, 1996.
• 池川 信夫, 藤本 善徳. ビタミンＤの活性代謝物の作用と化学合成，化学増刊１１８号，生態機能解明のための化学合成, 化学同人, 化学同人, No. 118, 1990.

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