@article{CTT100920585, author = {Keitaro Homma and Y. Miura* and M. Kobayashi and W. Chintrakulchai and M. Toyoda and K. Ogi and J. Michinishi and T. Ohtake and Y. Honda and T. Nomoto and H. Takemoto and N. Nishiyama}, title = {Fine tuning of the net charge alternation of polyzwitterion surfaced lipid nanoparticles to enhance cellular uptake and membrane fusion potential}, journal = {Sci. Technol. Adv. Mater.}, year = 2024, } @article{CTT100920582, author = {M. Matsui and Y. Kaihara and Y. Honda and N Nishiyama and Y. Miura}, title = {Site-activatable targeting of macromolecular alendronate for accelerated fracture healing}, journal = {Sci. Technol. Adv. Mater.}, year = 2023, } @article{CTT100920581, author = {Shan Gao and Y. Miura and A. Sumiyoshi and S. Ohno and K. Ogata and T. Nomoto and M. Matsui and Y. Honda and M. Suzuki and M. Iiyama and K. Osada and I. Aoki and N. Nishiyama}, title = {Self-folding macromolecular drug carrier for cancer imaging and therapy}, journal = {Advanced Science}, year = 2023, } @article{CTT100920580, author = {Xin Shen and A. Dirisala and M. Toyoda and Yao Xiao and H. Guo and Y. Honda and T. Nomoto and H. Takemoto and Y. Miura and N. Nishiyama}, title = {pH-Responsive polyzwitterion covered nanocarriers for DNA delivery}, journal = {J. Control. Release}, year = 2023, } @article{CTT100900226, author = {Haochen Guo and Xu Wen and Takahiro Nomoto and Kaito Kanamori and Yan Ming Voon and Yuto Honda and Naoki Yamada and Hiroyasu Takemoto and Makoto Matsui and Nobuhiro Nishiyama}, title = {Polymeric ligands comprising sulfur-containing amino acids for targeting tumor-associated amino acid transporters.}, journal = {Biomaterials}, year = 2023, } @article{CTT100900223, author = {Takahiro Nomoto and Kana Komoto and Tomoya Nagano and Takuya Ishii and Haochen Guo and Yuto Honda and Shun-ichiro OGURA and Masahiro Ishizuka and Nobuhiro Nishiyama}, title = {Polymeric iron chelators for enhancing 5-aminolevulinic acid-induced photodynamic therapy}, journal = {Cancer Sci.}, year = 2022, } @article{CTT100900217, author = {Yuto Honda and Sayaka Onodera and Hiroyasu Takemoto and Faizah Noor and Takahiro Nomoto and Makoto Matsui and Keishiro Tomoda and Yudi Sun and Yutaka Miura and Nobuhiro Nishiyama}, title = {Thermo-responsive polymer-siRNA conjugates enabling artificial control of gene silencing around body temperature}, journal = {Pharmaceutical Research}, year = 2022, } @article{CTT100900205, author = {Yijung Sung and Haochen Guo and Aria Ghasemizadeh and Xin Shen and Wanphiwat Chintrakulchai and Motoaki Kobayashi and Masahiro Toyoda and Koichi Ogi and Junya Michinishi and Tokoyuki Ohtake and Makoto Matsui and Yuto Honda and Takahiro Nomoto and Hiroyasu Takemoto and Yutaka Miura and Nobuhiro Nishiyama}, title = {Cancerous pH-responsive polycarboxybetaine-coated lipid nanoparticle for smart delivery of siRNA against subcutaneous tumor model}, journal = {Cancer Science}, year = 2022, } @article{CTT100876895, author = {Aziz Awaad and Hiroyasu Takemoto and Muneaki Iizuka and Koichi Ogi and Yuki Mochida and Abdul-Hackam Ranneh and Masahiro Toyoda and Makoto Matsui and Takahiro Nomoto and Yuto Honda and Kotaro Hayashi and Keishiro Tomoda and Tomoyuki Ohtake and Yutaka Miura and Nobuhiro Nishiyama}, title = {Changeable net charge on nanoparticles facilitates intratumor accumulation and penetration}, journal = {Journal of Controlled Release}, year = 2022, } @article{CTT100863940, author = {Yuto Honda* and Takahiro Nomoto and Makoto Matsui and Hiroyasu Takemoto and Yutaka Miura and Nobuhiro Nishiyama*}, title = {Sequentially Self-Assembled Nanoreactor Comprising Tannic Acid and Phenylboronic Acid-Conjugated Polymers Inducing Tumor-Selective Enzymatic Activity}, journal = {ACS Applied Materials and Interfaces}, year = 2021, } @article{CTT100863939, author = {Yuto Honda* and Takahiro Nomoto and Hiroyasu Takemoto and Makoto Matsui and Kaori Taniwaki and Haochen Guo and Yutaka Miura and Nobuhiro Nishiyama*}, title = {Systemically Applicable Glutamine-Functionalized Polymer Exerting Multivalent Interaction with Tumors Overexpressing ASCT2.}, journal = {ACS Applied Bio Materials}, year = 2021, } @article{CTT100837301, author = {Natsumi Fukuhara and Yuto Honda and Nao Ukita and Makoto Matsui and Yutaka Miura and Katsuyuki Hoshina}, title = {Efficient Suppression of Abdominal Aortic Aneurysm Expansion in Rats through Systemic Administration of Statin-Loaded Nanomedicine}, journal = {International Journal of Molecular Sciences}, year = 2020, } @article{CTT100835414, author = {Yuto Honda and Takahiro Nomoto and Makoto Matsui and Hiroyasu Takemoto and Yuka Kaihara and Yutaka Miura and Nobuhiro Nishiyama}, title = {Sequential Self-Assembly Using Tannic Acid and Phenylboronic Acid-Modified Copolymers for Potential Protein Delivery}, journal = {Biomacromolecules}, year = 2020, } @article{CTT100827009, author = {Hiroyasu Takemoto and Takanori Inaba and Takahiro Nomoto and Makoto Matsui and Gyomon Ryu and Masahiro Toyoda and Yuto Honda and Kaori Taniwaki and Naoki Yamada and Junhyun Kim and Keishiro Tomoda and Nobuhiro Nishiyama}, title = {Polymeric modification of gemcitabine via cyclic acetal linkage for enhanced anticancer potency with negligible side effects}, journal = {Biomaterials}, year = 2020, } @article{CTT100811952, author = {N. Yamada and Y. Honda and H. Takemoto and T. Nomoto and M. Matsui and K. Tomoda and M. Konno and H. Ishii and M. Mori and N. Nishiyama}, title = {Engineering tumour cell-binding synthetic polymers with sensing dense transporters associated with aberrant glutamine metabolism}, journal = {Scientific Reports}, year = 2017, } @inproceedings{CTT100900269, author = {本田雄士 and 長尾周平 and 喜納宏昭 and 松平望 and Xueying Liu and 野本貴大 and Anjaneyulu Dirisala and 三浦裕 and 片岡一則 and 西山伸宏}, title = {集束超音波と高分子複合体を組み合わせた脳選択的AAV送達システムの構築}, booktitle = {}, year = 2023, } @inproceedings{CTT100920606, author = {新田祥子 and 持田祐希 and 本田雄士 and 西山伸宏}, title = {cRGD 結合 PEG 修飾抗 PD-L1 抗体の開発と腫瘍標的性向上のための最適化}, booktitle = {}, year = 2023, } @inproceedings{CTT100920605, author = {Anudari Batbayar and 大橋遼太郎 and 本田雄士 and 野本貴大 and 三浦裕 and 西山伸宏}, title = {タンニン酸とフェニルボロン酸導入高分子から形成されるオボアルブミン内包三元系複合体の構築とがんワクチンアジュバントとしての応用}, booktitle = {}, year = 2023, } @inproceedings{CTT100920604, author = {登倉大貴 and 小成田翔 and 鈴木実 and 本田雄士 and 西山伸宏 and 野本貴大}, title = {PHPMA を基盤としたホウ素中性子捕捉療法用薬物送達システムの開発}, booktitle = {}, year = 2023, } @inproceedings{CTT100920597, author = {松平望 and 本田雄士 and 長尾周平 and 喜納宏明 and 野本貴大 and 三浦裕 and 西山伸宏}, title = {アデノ随伴ウイルス (AAV)の腫瘍選択性を向上させる環状ペプチドリガンド導入三元系 複合体の開発}, booktitle = {}, year = 2023, } @inproceedings{CTT100920596, author = {本田雄士 and 松尾拓海 and 野本貴大 and 西山伸宏}, title = {超分子複合体を基盤とした全身投与可能なCas9-sgRNP RNP送達システムの開発}, booktitle = {}, year = 2023, } @inproceedings{CTT100920594, author = {松平望 and 本田雄士 and 長尾周平 and 喜納宏明 and 野本貴大 and 三浦裕 and 西山伸宏}, title = {腫瘍標的機能を備えた環状ペプチド搭載アデノ随伴ウイルス(AAV)三元系複合体の開発}, booktitle = {}, year = 2023, } @inproceedings{CTT100920603, author = {Anudari Batbayar and 大橋遼太郎 and 本田雄士 and 野本貴大 and 三浦裕 and 西山伸宏}, title = {タンニン酸とフェニルボロン酸導入高分子から形成されるオボアルブミン内包三元系複合体の構築とがんワクチンアジュバントとしての応用}, booktitle = {}, year = 2023, } @inproceedings{CTT100920602, author = {小林基晃 and Ghasemizadeh Aria and 豊田真広 and Chintrakulchai Wanphiwat and Sung Yijung and Shen Xin and 本田雄士 and 野本貴大 and 三浦裕 and 西山伸宏}, title = {ポリベタイン修飾脂質ナノ粒子を用いたpH変化をトリガーとする腫瘍選択的siRNA送達システムの開発}, booktitle = {}, year = 2023, } @inproceedings{CTT100920601, author = {本田雄士 and Yao Xiao and 喜納宏明 and 西山伸宏}, title = {抗体耐性を中和するポリマーコーティングと組み合わせたアデノ随伴ウイルス(AAV)送達システムの開発}, booktitle = {}, year = 2023, } @inproceedings{CTT100920600, author = {本田雄士 and シャイクリザル エル ムツタキン and 西山 伸宏 and 野本 貴大}, title = {ボロン酸エステルを基盤とした細胞内相転移による高分子-細胞間相互作用制御および 薬物送達キャリアとしての応用}, booktitle = {}, year = 2023, } @inproceedings{CTT100920599, author = {本田雄士 and 松尾 拓海 and 野本貴大 and 刑部祐里子 and 西山伸宏}, title = {高分子三元系複合体を基盤とした全身投与型 Cas9-sgRNP RNP 送達システムの開発}, booktitle = {}, year = 2023, } @inproceedings{CTT100920598, author = {本田雄士 and 臼倉幸一 and 野本貴大 and 西山伸宏}, title = {ポリフェノールと自己会合型三元系複合体を形成するボロン 酸導入高分子の構造検討と機械学習を用いた解析}, booktitle = {}, year = 2023, } @inproceedings{CTT100900272, author = {松平望 and 本田雄士 and 長尾周平 and 喜納宏昭 and 野本貴大 and Xueying Liu and Anjaneyulu Dirisala and 三浦裕 and 片岡一則 and 西山伸宏}, title = {腫瘍細胞標的機能を備えた全身投与型アデノ随伴ウイルス(AAV)三元系複合体の開発}, booktitle = {}, year = 2022, } @inproceedings{CTT100876897, author = {本田雄士 and 長尾周平 and 喜納宏昭 and 野本貴大 and Liu Xueying and Dirisala Anjaneyulu and 松井誠 and 三浦裕 and 片岡一則 and 西山伸宏}, title = {アデノ随伴ウイルス(AAV)の中和抗体回避および活性を向上させるAAV内包三元系複合体}, booktitle = {}, year = 2022, } @inproceedings{CTT100876898, author = {松尾拓海 and 本田雄士 and 野本貴大 and 松井誠 and 三浦裕 and 西山伸宏}, title = {タンニン酸とフェニルボロン酸導入高分子で構築されたCas9 RNPデリバリーシステムの開発}, booktitle = {}, year = 2022, } @inproceedings{CTT100863942, author = {長尾周平 and 本田雄士 and 喜納宏昭 and 野本貴大 and Liu Xueying and Dirisala Anjaneyulu and 松井誠 and 三浦裕 and 片岡一則 and 西山伸宏}, title = {アデノ随伴ウイルス(AAV)中和抗体回避を可能にする全身投与型AAV搭載三元系複合体の開発}, booktitle = {}, year = 2021, } @inproceedings{CTT100863943, author = {本田雄士 and 山田直生 and 野本貴大 and 松井誠 and 西山伸宏}, title = {グルタミントランスポーターを高密度で発現しているがん細胞を認識する機能性高分子の開発}, booktitle = {}, year = 2021, } @inproceedings{CTT100863941, author = {松尾拓海 and 本田雄士 and 野本貴大 and 松井誠 and 三浦裕 and 西山伸宏}, title = {タンニン酸とフェニルボロン酸導入高分子の自己会合によって構成されたCas9 RNPデリバリーシステムの開発}, booktitle = {}, year = 2021, } @inproceedings{CTT100861662, author = {本田雄士 and 野本貴大 and 松井誠 and 三浦裕 and 西山伸宏}, title = {効率的なタンパク質送達を指向したタンニン酸とフェニルボロン酸導入高分子で構成されたタンパク質内包三元系複合体の構築}, booktitle = {}, year = 2021, } @inproceedings{CTT100861663, author = {松尾拓海 and 本田雄士 and 野本貴大 and 松井誠 and 三浦裕 and 西山伸宏}, title = {タンニン酸とフェニルボロン酸導入高分子で構築された自己会合型Cas9 RNP送達システムの開発}, booktitle = {}, year = 2021, } @inproceedings{CTT100861664, author = {臼倉幸一 and 本田雄士 and 野本貴大 and 松井誠 and 三浦裕 and 西山伸宏}, title = {官能基が異なるボロン酸導入高分子とタンニン酸で構成されたタンパク質三元系複合体の安定性評価}, booktitle = {}, year = 2021, } @inproceedings{CTT100861606, author = {Yuto Honda and Takahiro Nomoto and Makoto Matsui and Yutaka Miura and Nobuhiro Nishiyama}, title = {Construction of sequential self-assembled protein ternary complex utilizing boronic acid conjugated-polymer and tannic acid for protein delivery}, booktitle = {}, year = 2021, } @inproceedings{CTT100857503, author = {本田雄士 and 野本貴大 and 松井誠 and 三浦裕 and 西山伸宏}, title = {タンニン酸とフェニルボロン酸導入高分子の自己会合によって形成されたナノリアクターの酵素プロドラッグ療法への応用}, booktitle = {}, year = 2021, } @inproceedings{CTT100857508, author = {本田雄士 and 福原菜摘 and 浮田菜央 and 松井誠 and 大野哲史 and 野本貴大 and 西山伸宏 and 保科克行 and 三浦裕}, title = {ボロン酸エステルを介したスタチン内包高分子型ミセルの構築および薬理効果}, booktitle = {}, year = 2021, } @inproceedings{CTT100857507, author = {本田雄士 and 野本貴大 and 松井誠 and 三浦裕 and 西山伸宏}, title = {タンニン酸とフェニルボロン酸導入高分子から成る自己会合型ナノリアクターの構築および酵素プロドラッグ療法への応用}, booktitle = {}, year = 2021, } @inproceedings{CTT100857506, author = {長尾周平 and 本田雄士 and 喜納宏昭 and 野本貴大 and Liu Xueying and Dirisala Anjaneyulu and 松井誠 and 三浦裕 and 片岡一則 and 西山伸宏}, title = {アデノ随伴ウイルス(AAV)ベクターの中和抗体および副作用を克服するAAV/タンニン酸/ボロン酸導入高分子三元系複合体の構築}, booktitle = {}, year = 2021, } @inproceedings{CTT100857505, author = {大橋遼太郎 and 本田雄士 and 野本貴大 and 松井誠 and 三浦裕 and 西山伸宏}, title = {タンニン酸とフェニルボロン酸導入高分子で構成されるオボアルブミン封入三元系複合体の構築とがん免疫療法への応用}, booktitle = {}, year = 2021, } @inproceedings{CTT100857504, author = {松尾拓海 and 本田雄士 and 野本貴大 and 松井誠 and 三浦裕 and 西山伸宏}, title = {タンニン酸とフェニルボロン酸修飾高分子からなるCRISPR/Casタンパク質デリバリーシステムの開発}, booktitle = {}, year = 2021, } @inproceedings{CTT100836388, author = {I Dewa Agung Panji Dwipayana and Yuto Honda and Takahiro Nomoto and Hiroyasu Takemoto and Makoto Matsui and Yutaka Miura and Nobuhiro Nishiyama}, title = {Development of a versatile drug delivery system using tannic acid and boronic acid-conjugated polymer}, booktitle = {}, year = 2020, } @inproceedings{CTT100835424, author = {野本貴大 and 本田雄士 and 海原悠可 and 喜納宏昭 and 武元宏泰 and 松井誠 and 西山伸宏}, title = {タンニン酸とボロン酸ケミストリーを利用した高分子複合体の簡便調製法}, booktitle = {}, year = 2020, } @inproceedings{CTT100835417, author = {Yuto Honda and Takahiro NOMOTO and Makoto MATSUI and Hiroyasu TAKEMOTO and Yuka KAIHARA and Yutaka MIURA and Nobuhiro NISHIYAMA}, title = {Development of intracellular pH- responsive protein delivery system utilizing boronic acid-conjugated polymer and tannic acid}, booktitle = {}, year = 2020, } @inproceedings{CTT100813353, author = {本田雄士 and 山田直生 and 武元宏泰 and 野本貴大 and 松井誠 and 友田敬士郎 and 西山伸宏}, title = {がん細胞の高密度グルタミントランスポーターと選 択的な相互作用を示す機能性高分子の開発}, booktitle = {}, year = 2019, } @inproceedings{CTT100813344, author = {本田雄士 and 山田直生 and 武元宏泰 and 野本貴大 and 松井誠 and 友田敬士郎 and 西山伸宏}, title = {がん細胞の高密度グルタミントランスポーターを標的として選択的な相互作用を示す機能性高分子の開発}, booktitle = {}, year = 2019, } @inproceedings{CTT100811939, author = {Yuto Honda and Naoki Yamada and Takahiro Nomoto and Yukiya Inoue and Ying Yao and Minoru Suzuki and Kaito Kanamori and Hiroyasu Takemoto and Makoto Matsui and Keishiro Tomoda and Nobuhiro Nishiyama}, title = {Tumor cell-targeting glutamine-derived polymer that can interact with high density glutamine transporter based on aberrant glutamine metabolism.}, booktitle = {}, year = 2018, } @inproceedings{CTT100774000, author = {本田雄士 and 山田 直生 and 武元 宏泰 and 野本 貴 大 and 松井 誠 and 友田 敬士郎 and 西山 伸宏}, title = {グルタミン代謝が亢進したがん細胞の高密度グルタ ミントランスポーターを認識してアフィニティを示す機能性高 分子}, booktitle = {}, year = 2018, } @inproceedings{CTT100773989, author = {Naoki Yamada and Yuto Honda and Hiroyasu Takemoto and Takahiro Nomoto and Makoto Matsui and Keishiro Tomoda and Nobuhiro Nishiyama}, title = {Glutamine-Functionalized Polymer for Tumor-Selective High Affinity by Sensing Dense Glutamine Transporters Associated with Aberrant Metabolism}, booktitle = {}, year = 2017, } @inproceedings{CTT100773987, author = {山田直生 and 本田雄士 and 武元宏泰 and 野本貴大 and 松井 誠 and 友田敬士郎 and 西山伸宏}, title = {がん選択的に相互作用するグルタミン担持高分子の創製と機能評価}, booktitle = {}, year = 2017, } @inproceedings{CTT100752097, author = {Naoki Yamada and Yuto Honda and Hiroyasu Takemoto and Takahiro Nomoto and Makoto Matsui and Keishiro Tomoda and Nobuhiro Nishiyama}, title = {Design of synthetic polymer toward achieving a selective high affinity to tumor cells by interacting with dense glutaminolysis-related transporters}, booktitle = {}, year = 2017, } @inproceedings{CTT100752161, author = {Yuto Honda and Naoki Yamada and Hiroyasu Takemoto and Takahiro Nomoto and Makoto Matsui and Keishiro Tomoda and Nobuhiro Nishiyama}, title = {Novel design of glutamine-derived polymer with a high affinity to cancer cells based on aberrant glutamine metabolism.}, booktitle = {}, year = 2017, } @inproceedings{CTT100752144, author = {Naoki Yamada and Yuto Honda and Hiroyasu Takemoto and Takahiro Nomoto and Makoto Matsui and Keishiro Tomoda and Nobuhiro Nishiyama}, title = {Novel glutamine-based polymeric ligand for transporter-mediated tumor targeting}, booktitle = {}, year = 2016, } @misc{CTT100884501, author = {Yuto Honda}, title = {Construction of polyphenol/phenylboronic acid-conjugated polymer complexes-based drug delivery system}, year = 2021, } @misc{CTT100884502, author = {Yuto Honda}, title = {Construction of polyphenol/phenylboronic acid-conjugated polymer complexes-based drug delivery system}, year = 2021, } @misc{CTT100884503, author = {Yuto Honda}, title = {Construction of polyphenol/phenylboronic acid-conjugated polymer complexes-based drug delivery system}, year = 2021, } @misc{CTT100884504, author = {Yuto Honda}, title = {Construction of polyphenol/phenylboronic acid-conjugated polymer complexes-based drug delivery system}, year = 2021, } @misc{CTT100927751, author = {西山伸宏 and 本田雄士 and 野本貴大 and 武元宏泰 and 松井誠 and 喜納 宏昭 and 片岡 一則 and 劉 学蛍 and ディリサラ アンジャネユル}, title = {複合体、医薬、癌治療剤、キット及び結合体}, howpublished = {登録特許}, year = 2024, month = {}, note = {特願2021-522894(2020/05/29), WO 2020/241819(2020/12/03), 特許第7536258号(2024/08/09)} } @misc{CTT100869592, author = {西山伸宏 and 本田雄士 and 野本貴大 and 武元宏泰 and 松井誠 and 喜納 宏昭 and 片岡 一則 and 劉 学蛍 and Dirisala, Anjaneyulu}, title = {複合体、医薬、癌治療剤、キット及び結合体}, howpublished = {公開特許}, year = 2020, month = {}, note = {PCT/JP2020/021301(2020/05/29), WO 2020/241819(2020/12/03)} } @misc{CTT100806622, author = {西山伸宏 and 武元宏泰 and 野本貴大 and 友田敬士郎 and 松井誠 and 山田直生 and 本田雄士 and 森 正樹 and 石井 秀始 and 今野 雅允}, title = {グルタミントランスポーターと多価結合することができるリガンド、及び当該リガンドを含む組成物}, howpublished = {登録特許}, year = 2022, month = {}, note = {特願2018-535630(2017/08/17), 特開(再表)2018-037996(2019/06/20), 特許第7076104号(2022/05/19)} } @phdthesis{CTT100884501, author = {Yuto Honda}, title = {Construction of polyphenol/phenylboronic acid-conjugated polymer complexes-based drug delivery system}, school = {東京工業大学}, year = 2021, } @phdthesis{CTT100884502, author = {Yuto Honda}, title = {Construction of polyphenol/phenylboronic acid-conjugated polymer complexes-based drug delivery system}, school = {東京工業大学}, year = 2021, } @phdthesis{CTT100884503, author = {Yuto Honda}, title = {Construction of polyphenol/phenylboronic acid-conjugated polymer complexes-based drug delivery system}, school = {東京工業大学}, year = 2021, } @phdthesis{CTT100884504, author = {Yuto Honda}, title = {Construction of polyphenol/phenylboronic acid-conjugated polymer complexes-based drug delivery system}, school = {東京工業大学}, year = 2021, }