論文

• Hung Wei Lai, Yukitaka Tani, Udomlak Sukatta, Prapassorn Rugthaworn, Asada Thepyos, Shinkuro Yamamoto, Hideo Fukuhara, Keiji Inoue, Hideya Yuasa, Hiroyuki Nakamura, Shun-ichiro Ogura. Mangostin enhances efficacy of aminolevulinic acid-photodynamic therapy against cancer through inhibition of ABCG2 activity, Photodiagnosis and Photodynamic Therapy, Vol. 44, Sept. 2023.
• Hung Wei Lai, Moe Kasai, Shinkuro Yamamoto, Hideo Fukuhara, Takashi Karashima, Atsuhi Kurabayashi, Mutsuo Furihata, Kazuhiro Hanazaki, Keiji Inoue, Shun-ichiro Ogura. Metabolic shift towards oxidative phosphorylation reduces cell-density-induced cancer-stem-cell-like characteristics in prostate cancer in vitro, Biology Open, Vol. 12, Apr. 2023.
• Hung Wei Lai, Shinkuro Yamamoto, Hideo Fukuhara, Shun-ichiro Ogura, Keiji Inoue. Cell senescence-associated porphyrin metabolism affects the efficacy of aminolevulinic acid-photodynamic diagnosis in bladder cancer, Photodiagnosis and Photodynamic Therapy, Vol. 42, Apr. 2023.
• 小倉俊一郎, 中山沢, 山本新九郎, 福原秀雄, 花﨑和弘, 井上啓史. 5-アミノレブリン酸を用いた休眠がん細胞を標的とする光線力学療法, 日本レーザー医学会誌, Vol. 43, No. 4, pp. 238-248, Nov. 2022.
• Keiji Inoue, Hideo Fukuhara, Shinkuro Yamamoto, Takashi Karashima, Atsushi Kurabayashi, Mutsuo Furihata, Kazuhiro Hanazaki, Hung Wei Lai, Shun-Ichiro Ogura. Current status of photodynamic technology for urothelial cancer, Cancer Science, Vol. 113, Dec. 2021.
• Shumpei Morisawa, Kohei Jobu, Tomoaki Ishida, Kei Kawada, Hitoshi Fukuda, Yu Kawanishi, Taku Nakayama, Shinkuro Yamamoto, Naohisa Tamura, Mitsuhiro Takemura, Nao Kagimoto, Tsuyoshi Ohta, Noritaka Masahira, Hideo Fukuhara, Shun-ichiro Ogura, Tetsuya Ueba, Keiji Inoue, Mitsuhiko Miyamura. Association of 5-aminolevulinic acid with intraoperative hypotension in malignant glioma surgery, Photodiagnosis and Photodynamic Therapy, Vol. 37, Nov. 2021.
• Shinkuro Yamamoto, Taku Nakayama, Hitomi Seki, Chiaki Kawada, Hideo Fukuhara, Takashi Karashima, Shun-Ichiro Ogura, Keiji Inoue. Sunitinib with photoirradiation-mediated reactive oxygen species generation induces apoptosis of renal cell carcinoma cells, Photodiagnosis and Photodynamic Therapy, Vol. 35, July 2021.
• Shinkuro Yamamoto, Hideo Fukuhara, Hitomi Seki, Chiaki Kawada, Taku Nakayama, Takashi Karashima, Shun-Ichiro Ogura, Keiji Inoue. Predictors of therapeutic efficacy of 5-aminolevulinic acid-based photodynamic therapy in human prostate cancer, Photodiagnosis and Photodynamic Therapy, Vol. 35, July 2021.
• Taku Nakayama, Tomonori Sano, Yoshiki Oshimo, Chiaki Kawada, Moe Kasai, Shinkuro Yamamoto, Hideo Fukuhara, Keiji Inoue, Shun-ichiro Ogura. Enhanced lipid metabolism induces the sensitivity of dormant cancer cells to 5-aminolevulinic acid-based photodynamic therapy, Scientific Reports, Vol. 11, Apr. 2021.
• Taku Nakayama, Naoko Nozawa, Chiaki Kawada, Shinkuro Yamamoto, Takuya Ishii, Masahiro Ishizuka, Tsutomu Namikawa, Shun-ichiro Ogura, Kazuhiro Hanazaki, Keiji Inoue, Takashi Karashima. Mitomycin C-induced cell cycle arrest enhances 5-aminolevulinic acid-based photodynamic therapy for bladder cancer, Photodiagnosis and Photodynamic Therapy, Vol. 31, pp. 101893, Sept. 2020.
• Taku Nakayama, Tatsuya Kobayashi, Otsuka Shinpei, Hideo Fukuhara, Tsutomu Namikawa, Keiji Inoue, Kazuhiro Hanazaki, Kiwamu Takahashi, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. Photoirradiation after aminolevulinic acid treatment suppresses cancer cell proliferation through the HO-1/p21 pathway, Photodiagnosis and photodynamic therapy, Vol. 28, pp. 10-17, Dec. 2019.
• Taku Nakayama, Shinpei Otsuka, Tatsuya Kobayashi, Hodaka Okajima, Kentaro Matsumoto, Yuichiro Hagiya, Keiji Inoue, Taro Shuin, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy, Scientific Reports, Vol. 6, No. 36478, Nov. 2016.
• Shihu Wei, Hideo Fukuhara, Chiaki Kawada, Atsushi Kurabayashi, Mutsuo Furihata, Shun-ichiro Ogura, Keiji Inoue, Taro Shuin. Silencing of ATPase inhibitory factor 1 inhibits cell growth via cell cycle arrest in bladder cancer, Pathobiology, 82, 224-232, Sept. 2015.
• Urara Ota, Hideo Fukuhara, Masahiro Ishizuka, Fuminori Abe, Chiaki Kawada, Kenji Tamura, Tohru Tanaka, Keiji Inoue, Shun-ichiro Ogura, Taro Shuin. Plasma protoporphyrin IX following administration of 5-aminolevulinic acid as a potential tumor marker, Molecular and Clinical Oncology, 11, 1813-1819, July 2015.
• Maiko Hayashi, Hideo Fukuhara, Keiji Inoue, Taro Shuin, Yuichiro Hagiya, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. The effect of iron ion on the specificity of photodynamic therapy with 5-aminolevulinic acid, PLOS ONE, 10, e0122351, Mar. 2015.

国際会議発表 (査読有り)

• Taku Nakayama, Shinpei Otsuka, Kazuhiro Hanazaki, Keiji Inoue, Taro Shuin, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. Dormant Cancer Cells Accumulate High Protoporphyrin IX Levels And Are Sensitive To 5-aminolevulinic Acid-based Photodynamic Therapy, 17th International Photodynamic Association World Congress, June 2019.

国際会議発表 (査読なし・不明)

• Lai HW,  Yamamoto S, Takahashi K, Nakajima M, Hanazaki K, Inoue K, Ogura S. Novel strategy to increase specificity of aminolevulinic acid-photodynamic therapy in cancer, 5th International Conference on Molecular Biology & Biotechnology 2022, June 2022.
• Shinkuro Yamamoto, Taku Nakayama, Hideo Fukuhara, Takashi Karashima, Shun-Ichiro Ogura, Keiji Inoue. Sunitinib with photoirradiation critically response on renal cancer, The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem 2021), Dec. 2021.
• Yamamoto S, Nakayama T, Fukuhara H, Karashima T, Ogura S, Inoue K. Sunitinib-PDT mediated ROSs generation induces apoptosis on renal cancer cells, Photodynamic Therapy and Photodiagnosis Update 2020, Nov. 2020.
• Nakayama T, Nozawa N, Kawada C, Yamamoto S, Ishii T, Ishizuka M, Namikawa T, Ogura S, Hanazaki K, Inoue K, Karashima T.. Mitomycin C-induced cell cycle arrest enhances 5-aminolevulinic acid-based photodynamic therapy for bladder cancer, Photodynamic Therapy and Photodiagnosis Update 2020, Nov. 2020.
• Taku Nakayama, Masuomi Kaneko, Airi Saito, Shinkuro Yamamoto, Shun-ichiro Ogura, Keiji Inoue, Kazuhiro Hanazaki, Yosuke Niko. Amplify PpIX Fluorescence Via FRET With Giant Light-harvesting Nanoantenna System: Ex-vitro Trial, The 7 th International ALA and Porphyrin Symposium, Dec. 2019.
• Taku Nakayama, Shimpei Otsuka, Kazuhiro Hanazaki, Keiji Inoue, Taro Shuin, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. Dormant Cancer Cells Accumulate High Protoporphyrin IX Levels And Are Sensitive To 5-aminolevulinic Acid-based Photodynamic Therapy, 6th International ALA and Porphyrin Symposium, Oct. 2018.
• Shun-ichiro Ogura, Taku Nakayama, Keiji Inoue, Motowo Nakajima, Tohru Tanaka. Applications of Aminolevulinic acid in tumor – From Diagnosis and Therapy to Screening, Photodynamic Therapy and Photodiagnosis Update 2018, Sept. 2018.
• Shun-ichiro Ogura, Keiji Inoue, Hideo Fukuhara, Motowo Nakajima, Tohru Tanaka. Porphyrins as urinary biomarkers for bladder cancer after 5-aminolevulinic acid administration: The potential of photodynamic screening for tumors, The 5th International ALA and Porphyrin Symposium, Dec. 2017.

国内会議発表 (査読なし・不明)

• Lai Hung Wei, 小倉 俊一郎, 山本新九郎, 福原秀雄, 井上啓史. 細胞老化に伴うポルフィリン代謝がアミノレブリン酸を用いた光線力学的がん診断に与える影響, 第5回 泌尿器光力学研究会学術集会, Nov. 2022.
• 井上啓史, 山本新九郎, 福原秀雄, Lai Hung Wei, 小倉俊一郎. 光線力学診断 (PDD) の今 光線力学スクリーニング (PDS) の未来, 第30回 日本がん検診・診断学会総会 シンポジウム, Sept. 2022.
• 小倉俊一郎, 井上啓史. アミノレブリン酸を用いたがんの光線力学診療, 第26回日本がん分子標的治療学会学術集会, July 2022.
• Hung Wei Lai, 山本新九郎, 福原秀雄, 花崎和弘, 井上啓史, 小倉俊一郎. 異なるがん悪性度でALA取り込みトラン ポーター発現量の変化におけるALA-PDT の効率, 第10回ポルフィリン・ALA学会, Mar. 2022.
• Hung Wei Lai, 山本新九郎, 福原秀雄, 花崎和弘, 井上啓史, 小倉俊一郎. 前立腺がんにおけるアミノレブリ酸を用いた光線力学療法のがん特異性を向上させる新規戦略, 第31回泌尿器科分子・細胞研究会, Feb. 2022.
• Hung Wei Lai, 山本新九郎, 福原秀雄, 花崎和弘, 井上啓史, 小倉俊一郎. アミノレブリン酸（ALA）を用いた光線力学療法におけるALA取り込みトランスポーターの役割, 第8回先端PDDTフォーラム, Nov. 2021.
• 小倉俊一郎, 井上啓史. PDDの未来～光線力学診断から光線力学スクリーニングまで～, LASERWEEK in TOKYO II, Oct. 2021.
• 山本新九郎, 福原秀雄, 中山 沢, 小倉俊一郎, 井上啓史. 前立腺癌における ABCG2 トランスポーターの発現評価はALA-PDTの治療効果予測因子となり得る, 第7回先端PDDTフォーラム, Dec. 2020.
• 中山 沢, 野澤菜緒子, 川田千明, 山本新九郎, 福原秀雄, 石井琢也, 石塚昌宏, 小倉俊一郎, 井上啓史, 辛島 尚. 膀胱がんにおけるマイトマイシンCと5-ALA-PDTの併用効果, 第7回先端PDDTフォーラム, Dec. 2020.
• 山本新九郎, 福原秀雄, 中山沢, 小倉俊一郎, 井上啓史. 前立腺癌細胞における5-アミノレブリン酸によるPDTの治療効果予測因子としてのABCG2トランスポーターの発現評価, LASER WEEK in KOCHI, Oct. 2020.
• 中山 沢, 山本新九郎, 花崎和弘, 井上啓史, 中島元夫, 田中 徹, 小倉俊一郎. 休眠がん細胞における5-ALA-PDTの評価, LASER WEEK in KOCHI, Oct. 2020.
• Nakayama T, Takahashi K, Nakajima M, Inoue K, Ogura S. Mitomycin C-induced cell cycle arrest enhances 5-aminolevulinic acid-based photodynamic therapy for bladder cancer, 第79回日本癌学会学術総会, Oct. 2020.
• 小倉俊一郎, 井上啓史. アミノレブリン酸を用いたがんの光線力学診療, LASER WEEK in KOCHI, Oct. 2020.
• 中山 沢, 大塚慎平, 花崎和弘, 井上啓史, 中島元夫, 田中 徹, 小倉俊一郎. 休眠がん細胞における5-ALA-PDTの評価, 第38回日本ヒト細胞学会学術集会, Aug. 2020.
• 小倉俊一郎, 井上啓史. アミノレブリン酸を用いたがんの光線力学診療, 第81回日本臨床外科学会総会, Nov. 2019.
• 小倉俊一郎, 井上啓史. アミノレブリン酸を用いたがんの光線力学診療, 第57回日本癌治療学会学術集会, Oct. 2019.
• 中山沢, 小林竜也, 高橋究, 中島元夫, 田中徹, 福原秀雄, 井上啓史, 小倉俊一郎. 腫瘍細胞におけるALA-PDT後の遺伝子変化および細胞増殖評価, 第40回日本レーザー医学会総会, Oct. 2019.
• 小倉俊一郎, 中山沢, 大塚慎平, 中島元夫, 田中徹, 山本新九郎, 花崎和弘, 井上啓史. 休眠がん細胞モデルにおけるALA添加後のPpIX蓄積およびPDT感受性の評価, 2019年 日本光線力学学会・日本脳神経外科光線力学学会 合同学術講演会, Sept. 2019.
• 中山沢, 小林竜也, 高橋究, 中島元夫, 田中徹, 福原秀雄, 井上啓史, 小倉俊一郎. 腫瘍細胞におけるALA-PDT後の遺伝子変化および細胞増殖評価, 第9回 ポルフィリン-ALA学会, Apr. 2019.
• 小倉俊一郎, 林麻衣子, 福原秀雄, 井上啓史, 執印太郎, 中島元夫, 田中徹. アミノレブリン酸を用いたがんの光線力学療法における鉄イオンの役割, 先端錯体工学研究会2017年度年会, Aug. 2017.

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