論文

• Shuya Fan, Jie Xu, Yasuko Osakada, Katsunori Hashimoto, Kazuya Takayama, Atsushi Natsume, Masaki Hirano, Atsushi Maruyama, Mamoru Fujitsuka, Kumi Kawai, Kiyohiko Kawai. Electron-transfer kinetics through nucleic acids untangled by single-molecular fluorescence blinking, Chem, Cell Press, Vol. 8, No. 11, pp. 3109-3119, Sept. 2022.
• Zouyue Liu, Hieu Thi Minh Nguyen, Daiki Asanuma, Sachiko Tojo, Minoru Yamaji, Kiyohiko Kawai, Guillem Pratx, Mamoru Fujitsuka, Yasuko Osakada. Red, green, and blue radio-luminescent polymer dots doped with heteroleptic tris-cyclometalated iridium complexes, RSC Advances, Royal Society of Chemistry, Vol. 13, No. 22, pp. 15126-15131, May 2023.
• Daiki Asanuma, Hieu Thi Minh Nguyen, Zuoyue Liu, Sachiko Tojo, Hajime Shigemitsu, Minoru Yamaji, Kiyohiko Kawai, Tadashi Mori, Toshiyuki Kida, Guillem Pratx, Mamoru Fujitsuka, Yasuko Osakada. Radioluminescence from polymer dots based on thermally activated delayed fluorescence, Nanoscale Advances, Royal Society of Chemistry, Vol. 5, No. 13, pp. 3424-3427, May 2023.
• Shuya Fan, Tadao Takada, Atsushi Maruyama, Mamoru Fujitsuka, Kiyohiko Kawai. Programmed Control of Fluorescence Blinking Patterns based on Electron Transfer in DNA, Chemistry - A European Journal, Wiley-VCH Verlag GmbH & Co. KGaA, Vol. 29, No. 19, pp. e202203552, Jan. 2023.
• Shuya Fan, Tadao Takada, Atsushi Maruyama, Mamoru Fujitsuka, Kiyohiko Kawai. Large Heterogeneity Observed in Single Molecule Measurements of Intramolecular Electron Transfer Rates through DNA, Bulletin of the Chemical Society of Japan, Chemical Society of Japan, Vol. 95, No. 12, pp. 1697-1702, Dec. 2022.
• Kiyohiko Kawai, Mamoru Fujitsuka. Single-molecule Fluorescence Kinetic Sandwich Assay Using a DNA Sequencer, Chemistry Letters, Chemical Society of Japan, Vol. 51, No. 2, pp. 139-141, Jan. 2022.
• Tadao Takada, Koma Nishida, Yurika Honda, Aoi Nakano, Mitsunobu Nakamura, Shuya Fan, Kiyohiko Kawai, Mamoru Fujitsuka, Kazushige Yamana. Stacked Thiazole Orange Dyes in DNA Capable of Switching Emissive Behavior in Response to Structural Transitions, ChemBioChem, Wiley-VCH Verlag GmbH & Co. KGaA, Vol. 22, No. 17, pp. 2729-2735, June 2021.
• Jie Xu, Shuya Fan, Lei Xu, Mamoru Fujitsuka, Kiyohiko Kawai, Atsushi Maruyama. Control of Triplet Blinking Using Cyclooctatetraene to Access the Dynamics of Biomolecules at the Single-Molecule Level, Angewandte Chemie, International Edition, Wiley-VCH Verlag GmbH & Co. KGaA, Vol. 60, No. 23, pp. 12941-12948, Mar. 2021.  公式リンク  
  
• Jie Xu, Shuya Fan, Lei Xu, Mamoru Fujitsuka, Kiyohiko Kawai, Atsushi Maruyama. Control of Triplet Blinking Using Cyclooctatetraene to Access the Dynamics of Biomolecules at the Single-Molecule Level, Angewandte Chemie, International Edition, Wiley-VCH Verlag GmbH & Co. KGaA, Vol. 60, No. 23, pp. 12941-12948, Mar. 2021.  公式リンク  
  
• Kiyohiko Kawai, Mamoru Fujitsuka, Atsushi Maruyama. Single-Molecule Study of Redox Reaction Kinetics by Observing Fluorescence Blinking, Accounts of Chemical Research, American Chemical Society, Vol. 54, No. 4, pp. 1001-1010, Feb. 2021.  公式リンク  
  
• Jie Xu, Sachiko Tojo, Mamoru Fujitsuka, Kiyohiko Kawai. Dynamics of Single-Stranded RNA Looping Probed and Photoregulated by Sulfonated Pyrene, ChemistrySelect, Wiley-VCH Verlag GmbH & Co. KGaA, Vol. 5, No. 26, pp. 8002-8008, July 2020.
• Kiyohiko Kawai, Atsushi Maruyama. Kinetics of Photoinduced Reactions at the Single-Molecule Level: The KACB Method, Chemistry - A European Journal, Wiley-VCH Verlag GmbH & Co. KGaA, Vol. 26, No. 35, pp. 7740-7746, Feb. 2020.
• Jie Xu, Shunichi Miyamoto, Sachiko Tojo, Kiyohiko Kawai. Sulfonated Pyrene as a Photoregulator for Single-Stranded DNA Looping, Chemistry - A European Journal, Wiley-VCH Verlag GmbH & Co. KGaA, Vol. 26, No. 22, pp. 5075-5084, Feb. 2020.
• Takafumi Miyata, Naohiko Shimada, Atsushi Maruyama, Kiyohiko Kawai. Fluorescence Redox Blinking Adaptable to Structural Analysis of Nucleic Acids, Chemistry - A European Journal, Wiley-VCH Verlag GmbH & Co. KGaA, Vol. 24, No. 26, pp. 6755-6761, May 2018.  公式リンク  
  
• Kiyohiko Kawai, Takafumi Miyata, Naohiko Shimada, Syoji Ito, Hiroshi Miyasaka, Atsushi Maruyama. Single-Molecule Monitoring of the Structural Switching Dynamics of Nucleic Acids through Controlling Fluorescence Blinking, Angewandte Chemie, International Edition, Wiley-VCH Verlag GmbH & Co. KGaA, Vol. 56, No. 48, pp. 15329-15333, Oct. 2017.
• Kiyohiko Kawai, Eri Matsutani, Atsushi Maruyama, Tetsuro Majima. Probing the Charge-Transfer Dynamics in DNA at the Single-Molecule Level, Journal of the American Chemical Society, American Chemical Society, Vol. 133, No. 39, pp. 15568-15577, Aug. 2011.  公式リンク  
  
• Kiyohiko Kawai, Yasuko Osakada, Eri Matsutani, Tetsuro Majima. Charge Separation and Photosensitized Damage in DNA Mediated by Naphthalimide, Naphthaldiimide, and Anthraquinone, Journal of Physical Chemistry B, American Chemical Society, Vol. 114, No. 31, pp. 10195-10199, July 2010.
• Kazuki Tainaka, Mamoru Fujitsuka, Tadao Takada, Kiyohiko Kawai, Tetsuro Majima. Sequence Dependence of Excess Electron Transfer in DNA, Journal of Physical Chemistry B, American Chemical Society, Vol. 114, No. 45, pp. 14657-14663, May 2010.
• Kiyohiko Kawai, Eri Matsutani, Tetsuro Majima. 8-Oxo-7,8-dihydro-2'-deoxyguanosine produces a long-lived charge-separated state during the photosensitized one-electron oxidation of DNA resulting in efficient and exclusive degradation, Chemical Communications (Cambridge, United Kingdom), Royal Society of Chemistry, Vol. 46, No. 19, pp. 3277-3279, Mar. 2010.
• Kiyohiko Kawai, Haruka Kodera, Tetsuro Majima. Long-Range Charge Transfer through DNA by Replacing Adenine with Diaminopurine, Journal of the American Chemical Society, American Chemical Society, Vol. 132, No. 2, pp. 627-630, 2010.

国際会議発表 (査読なし・不明)

• Shuya Fan, Tadao Takada, Atsushi Maruyama, Mamoru Fujitsuka, Kiyohiko Kawai. Blinking as an Additional Fluorescence-Based Readout Parameter: Blinking controlled by Electron Transfer through DNA, The 50th International Symposium on Nucleic Acids Chemistry, Nov. 2024.
• Kiyohiko Kawai. Single molecule study of electron transfer through DNA, The 31st International Conference on Photochemistry, July 2024.
• Kiyohiko Kawai. Red, green, and blue radio-luminescent polymer dots doped with heteroleptic tris-cyclometalated iridium complexes, The 31st International Conference on Photochemistry, July 2024.
• Kiyohiko KAWAI. Single molecule analysis and diagnosis by monitoring fluorescence blinking, 12th Tokyo Tech International Symposium on Life Science and Technology, Jan. 2024.
• Shuya FAN, Jie XU, Yasuko OSAKADA, Katsunori HASHIMOTO, Kazuya TAKAYAMA, Atsushi NATSUME, Masaki HIRANO, Atsushi MARUYAMA, Mamoru FUJITSUKA, Kumi KAWAI, Kiyohiko KAWAI. In situ single molecule identification of point mutations in tumor cell block specimens by monitoring fluorescence blinking, The 49th International Symposium on Nucleic Acids Chemistry, Nov. 2022.
• 川井 清彦, 丸山 厚, Mamoru FUJITSUKA. Single molecule analysis and diagnosis by measuring chemical reaction rates, Jan. 2022.

国内会議発表 (査読なし・不明)

• 中村和磨, 近藤洋平, 丸山厚, 川井清彦, 高田忠雄, 藤塚守. 物質科学動的データに対する隠れマルコフシミュレーション： DNA分子の蛍光時系列データ解析, 日本物理学会 2024年春季大会, Mar. 2024.
• 范 姝亜, 高田 忠雄, 丸山 厚, 藤塚 守, 川井清彦. DNA内電子移動による1分子蛍光blinkingの制御と情報読み分け, 第17回バイオ関連化学シンポジウム, Sept. 2023.
• 土取 章太郎, 米澤 祐基, 范 姝亜, 丸山 厚, 藤塚 守, 川井 清彦. レドックス制御型蛍光blinkingを用いた生体還元剤の定量, Mar. 2023.
• 川井清彦. 蛍光の点滅現象＝blinking観測に基づく1分子分析・診断, バイオ機能医工学研究領域セミナー, Feb. 2023.
• 川井清彦. 1分子蛍光blinking観測に基づく分析・診断法, 日本環境変異ゲノム学会, Nov. 2022.
• FAN Shuya, MARUYAMA Atsushi, FUJITSUKA Mamoru, KAWAI Kiyohiko. Distance-dependent electron transfer kinetics in DNA at the single-molecule level, 光化学討論会2023, Sept. 2022.
• Kiyohiko Kawai. Single-molecule photochemistry of nucleic acids and its application to single-molecule analysis and diagnosis, 光化学討論会2023, Sept. 2022.
• 范姝亜, 徐潔, 小阪田泰子, 橋本克訓, 髙山和也, 夏目敦至, 平野雅規, ATSUSHI MARUYAMA, 藤塚守, 川井久美, Kiyohiko Kawai. In situ detection of point mutation in tumor cell block specimens by monitoring single-molecule fluorescence blinking, 第16回バイオ関連化学シンポジウム, Sept. 2022.

その他の論文・著書など

• Kiyohiko Kawai, 丸山厚, 藤塚守. 蛍光分子を一つひとつ見ると ― 蛍光の点滅パターンから情報を読む ―, 化学, Kagaku Dojin, Vol. 77, No. 10, pp. 68-69, Oct. 2022.
• Xinxi Li, Kiyohiko Kawai, Mamoru Fujitsuka, Yasuko Osakada. COF-based photocatalyst for energy and environment applications, Surfaces and Interfaces, Elsevier B.V., Vol. 25, pp. 101249, June 2021.

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