論文

• Thi Kim Dung Doan, Masakazu Umezawa, Kyohei Okubo, Masao Kamimura, Kohei Soga. Enhancing near-infrared fluorescence intensity and stability of PLGA-b-PEG micelles by introducing Gd-DOTA at the core boundary, Journal of Biomedical Materials Research Part B: Applied Biomaterials, Wiley, Vol. 112, Issue 1, e35327, Jan. 2024.  公式リンク  
  
• Akino Mori, Masakazu Umezawa, Kyohei Okubo, Tomonori Kamiya, Masao Kamimura, Naoko Ohtani, Kohei Soga. Visualization of hydrocarbon chain length and degree of saturation of fatty acids in mouse livers by combining near-infrared hyperspectral imaging and machine learning, Scientific Reports, Springer Nature, Vol. 13, 20555, Nov. 2023.  公式リンク  
  
• Tomohiro Mitsui, Akino Mori, Toshihiro Takamatsu, Tomohiro Kadota, Konosuke Sato, Ryodai Fukushima, Kyohei Okubo, Masakazu Umezawa, Hiroshi Takemura, Hideo Yokota, Takeshi Kuwata, Takahiro Kinoshita, Hiroaki Ikematsu, Tomonori Yano, Shin Maeda, Kohei Soga. Evaluating the identification of the extent of gastric cancer by over-1000 nm near-infrared hyperspectral imaging using surgical specimens, Journal of Biomedical Optics, SPIE, Vol. 28, Issue 8, 086001, Aug. 2023.  公式リンク  
  
• Thi Kim Dung Doan, Masakazu Umezawa, Kazuno Ikeda, Kazunobu Ohnuki, Mizuki Akatsuka, Kyohei Okubo, Masao Kamimura, Masayuki Yamaguchi, Hirofumi Fujii, Kohei Soga. Influence of Carboxyl Group Ratios on the Design of Breast Cancer Targeting Bimodal MR/NIR-II Imaging Probe from PLGA@Gd-DOTA@PEG Micelles Conjugating Herceptin, ACS Applied Bio Materials, ACS Publications, June 2023.  公式リンク  
  
• Doan, T.K.D., Umezawa, M., Okubo, K., Kamimura, M., Masayuki Yamaguchi, Fujii, H., Soga, K.. The effect of Gd-DOTA locations within PLGA-b-PEG micelle encapsulated IR-1061 on bimodal over-1000 nm near-infrared fluorescence and magnetic resonance imaging, Biomaterials Science, Vol. 10, No. 21, pp. 6244-6257, Sept. 2022.  公式リンク  
  
• Umezawa, M., Miyata, K., Okubo, K., Soga, K.. Three Dimensional Lifetime-Multiplex Tomography Based on Time-Gated Capturing of Near-Infrared Fluorescence Images, Applied Sciences, July 2022.  公式リンク  
  
• Umezawa, M., Kobayashi, H., Ichihashi, K., Sekiyama, S., Okubo, K., Kamimura, M., Soga, K.. Heat Treatment Effects for Controlling Dye Molecular States in the Hydrophobic Core of Over-1000 nm Near-Infrared (NIR-II) Fluorescent Micellar Nanoparticles, ACS Omega, Vol. 7, No. 7, pp. 5817-5824, Feb. 2022.  公式リンク  
  
• Takematsu, M., Umezawa, M., Sera, T., Kitagawa, Y., Kurahashi, H., Yamada, S., Okubo, K., Kamimura, M., Yokota, H., Soga, K.. Influence of the difference in refractive index on the interface of an object and the surroundings in near-infrared fluorescence tomography, Applied Optics, Vol. 61, No. 2, pp. 638, Jan. 2022.  公式リンク  
  
• Ichihashi, K., Umezawa, M., Okubo, K., Ueya, Y., Takamoto, E., Matsuda, T., Kamimura, M., Soga, K.. Effect of the enantiomeric structure of hydrophobic polymers on the encapsulation properties of a second near infrared (NIR-II) fluorescent dye for in vivo deep imaging, RSC Advances, Vol. 12, No. 3, pp. 1310-1318, Jan. 2022.  公式リンク  
  
• Doan, T.K.D., Umezawa, M., Kazunobu Ohnuki, Okubo, K., Nigoghossian, K., Kamimura, M., Yamaguchi, M., Fujii, H., Soga, K.. The influence of Gd-DOTA ratios conjugating PLGA-PEG micelles encapsulated IR-1061 in bimodal over–1000 nm near–infrared fluorescence and magnetic resonance imaging, Biomaterials Science, Vol. 10, pp. 1217-1230, Jan. 2022.  公式リンク  
  
• Okubo, K., Takeda, R., Murayama, S., Umezawa, M., Kamimura, M., Osada, K., Aoki, I., Soga, K.. Size-controlled bimodal in vivo nanoprobes as near-infrared phosphors and positive contrast agents for magnetic resonance imaging, Science and Technology of Advanced Materials, Vol. 22, No. 1, pp. 160-172, Dec. 2021.  公式リンク  
  
• Okubo, K., Umezawa, M., Soga, K.. Near Infrared Fluorescent Nanostructure Design for Organic/Inorganic Hybrid System, Biomedicines, Vol. 9, Issue 11, Page 1583, Oct. 2021.  公式リンク  
  
• Okubo, K., Umezawa, M., Soga, K.. Review—Concept and Application of Thermal Phenomena at 4f Electrons of Trivalent Lanthanide Ions in Organic/Inorganic Hybrid Nanostructure, ECS Journal of Solid State Science and Technology, Vol. 10, No. 9, pp. 096006, Sept. 2021.  公式リンク  
  
• Nomura, K., Umezawa, M., Tezuka, K., Tasaki, T., Okubo, K, Soga, K.. Effect of polarization of surrounding organic molecules on upconversion emission of β-NaYF4 Co-Doped with Er3+ and Yb3+, Journal of Luminescence, Vol. 239, pp. 118394, Aug. 2021.  公式リンク  
  
• Tezuka, K., Umezawa, M., Liu, T.-I., Nomura, K., Okubo, K., Chiu, H.-C., Kamimura, M., Soga, K.. Upconversion Luminescent Nanostructure with Ultrasmall Ceramic Nanoparticles Coupled with Rose Bengal for NIR-Induced Photodynamic Therapy, ACS Applied Bio Materials, Vol. 4, No. 5, pp. 4462-4469, May 2021.  公式リンク  
  
• Takamatsu, T., Kitagawa, Y., Akimoto, K., Iwanami, R., Endo, Y., Takashima, K., Okubo, K., Umezawa, M., Kuwata, T., Sato, D., Kadota, T., Tomohiro Mitsui, Ikematsu, H., Yokota, H., Soga, K., Takemura, H.. Over 1000 nm Near-Infrared Multispectral Imaging System for Laparoscopic In Vivo Imaging, Sensors, Vol. 21, Issue 8, Page 2649, Apr. 2021.  公式リンク  
  
• Okubo, K., Yuichi Kitagawa, Hosokawa, N., Masakazu Umezawa, Masao Kamimura, Kamiya, T., Ohtani, N., Soga, K.. Visualization of quantitative lipid distribution in mouse liver through near-infrared hyperspectral imaging, Biomedical Optics Express, Vol. 12, No. 2, pp. 823-835, Jan. 2021.  公式リンク  
  
• Sato, D., Takamatsu, T., Masakazu Umezawa, Yuichi Kitagawa, Maeda, K., Hosokawa, N., Okubo, K., Masao Kamimura, Kadota, T., Akimoto, T., Kinoshita, T., Yano, T., Kuwata, T., Ikematsu, H., Takemura, H., Yokota, H., Soga, K.. Distinction of surgically resected gastrointestinal stromal tumor by near-infrared hyperspectral imaging, Scientific reports, Vol. 10, No. 1, pp. 21852, Dec. 2020.  公式リンク  
  
• Nigoghossian, K., Miyashita, T., Omura, A., Yeroslavsky, G., Doan, T.K.D., Okubo, K., Masakazu Umezawa, Masao Kamimura, Soga, K.. Infrared to visible upconversion luminescence of trivalent erbium tetrafluoroborate complexes, Optical Materials Express, Vol. 10, No. 10, pp. 1749-1766, July 2020.  公式リンク  
  
• Yeroslavsky, G., Okubo, K., Masakazu Umezawa, Nigoghossian, K., Dung, T.K.D., Miyata, K., Nomura, K., Masao Kamimura, Soga, K.. Energy transfer between rare earth-doped ceramic nanoparticles for gauging strain and temperature in elastic polymers, Journal of Photopolymer Science and Technology, Vol. 33, No. 1, pp. 129-137, July 2020.  公式リンク  
  
• Doan, T.K.D., Masakazu Umezawa, Nigoghossian, K., Yeroslavsky, G., Okubo, K., Masao Kamimura, Yamaguchi, M., Fujii, H., Soga, K.. Development of molecular imaging probe for dual NIR/MR imaging, Journal of Photopolymer Science and Technology, Vol. 33, No. 1, pp. 117-122, July 2020.  公式リンク  
  
• Yeroslavsky, G., Umezawa, M., Okubo, K., Nigoghossian, K., Doan, T.K.D., Miyata, K., Kamimura, M., Soga, K.. Stabilization of indocyanine green dye in polymeric micelles for NIR-II fluorescence imaging and cancer treatment, Biomaterials Science, Vol. 8, No. 8, pp. 2245-2254, Mar. 2020.  公式リンク  
  
• Chihara, T., Umezawa, M., Miyata, K., Sekiyama, S., Hosokawa, N., Kyohei Okubo, Masao Kamimura, Kohei Soga. Biological Deep Temperature Imaging with Fluorescence Lifetime of Rare-Earth-Doped Ceramics Particles in the Second NIR Biological Window, Scientific Reports, Vol. 9, No. 1, Sept. 2019.  公式リンク  
  

著書

• Soga, K., Okubo, K., Umezawa, M.. Transparency in Biology, Springer Singapore, Dec. 2021.  公式リンク  

国際会議発表 (査読有り)

• R. Fukushima, T. Takamatsu, A. Mori, K. Sato, K. Okubo, M. Umezawa, N. Takeshita, H. Hasegawa, H. Yokota, K. Soga, H. Takemura. Hyperspectral Imaging and Detection Mapping of In vivo Biological Tissues Applying Near-Infrared Laparoscope, SPIE Medical Imaging 2023: Image- Guided Procedures, Robotic Interventions, and Modeling, 124662K, Apr. 2023.  公式リンク  
  
• Kyohei Okubo, Masakazu Umezawa, Kohei Soga. Near infrared hyperspectral imaging for biomedical applications including lipid visualization in liver and submucosal tumor detection, Spectral shapIng for biomedical and energy applicaTions (SHIFT 2022), Oct. 2022.
• Kyohei Okubo, Masakazu Umezawa, Kohei Soga. Strategy for Designing Near Infrared Fluorescent Nanostructure with Organic and Inorganic Hybrid System, 5th International Conference on Chromogenic and Emissive Materials 2022 (I3CEM2022), July 2022.
• Kyohei Okubo, Masakazu Umezawa, Kohei Soga. Chemical Polarity for Designing Near Infrared Fluorescent Organic/Inorganic Hybrid Nanoprobes, 5th International Conference on Chromogenic and Emissive Materials 2022 (I3CEM2022), July 2022.
• Kohei Soga, Kyohei Okubo, Masakazu Umezawa, Doan Thi Kim Dung, Masao Kamimura. Rare-Earth Doped Ceramics for Near Infrared Bio and Medical Photonics, 14th Pacific Rim Conference on Ceramic and Glass Technology (PACRIM 14), Dec. 2021.
• Yahata, A., Takemura, H., Takamatsu, T., Yokota, H., Iwanami, R., Umezawa, M., Okubo, K., Soga, K., Mitsui, T., Kadota, T., Kuwata, T., Ikematsu, H.. Wavelength Selection of Near-Infrared Hyperspectral Imaging for Gastric Cancer Detection, 2021 6th International Conference on Intelligent Informatics and Biomedical Sciences (ICIIBMS), 2021 6th International Conference on Intelligent Informatics and Biomedical Sciences (ICIIBMS), 21530713, Dec. 2021.  公式リンク  
  

国内会議発表 (査読なし・不明)

• 森彬乃, 大久保喬平, 神谷知憲, 梅澤雅和, 上村真生, 大谷直子, 曽我公平. 近赤外ハイパースペクトルイメージングとサポートベクトル回帰分析によるマウス肝臓中脂肪酸の飽和度分布の可視化, 第31回日本バイオイメージング学会学術集会, バイオイメージング, Vol. 31, No. 2, p. 125, Aug. 2022.
• 森 彬乃, 岩波廉, 梅澤雅和, 大久保喬平, 曽我公平, 高松利寛, 桑田健, 門田智裕, 三井智弘, 池松弘朗, 横田秀夫, 福島 諒大, 竹村裕. 近赤外ハイパースペクトルイメージングを用いた消化間質腫瘍と胃がんの識別及び軟性内視鏡デバイスの開発, 日本分光学会年次講演会, p. 53, Oct. 2021.
• 竹松真歩, 梅澤雅和, 世良俊博, 横田秀夫, 大久保喬平, 上村真生, 曽我公平. 試料表面の屈折率差が近赤外蛍光CTに及ぼす影響, 第30回日本バイオイメージング学会学術集会, バイオイメージング, Vol. 30, Issue 2, p. 65, Aug. 2021.
• 市橋理江, 梅澤雅和, 植屋佑一, 高本英司, 大久保喬平, 上村真生, 曽我公平. 疎水性高分子の立体構造がOTN近赤外蛍光色素の内包特性に及ぼす影響, 第30回日本バイオイメージング学会学術集会, バイオイメージング, Vol. 30, Issue 2, p. 66, Aug. 2021.
• 竹松真歩, 宮田敬充, 梅澤雅和, 世良俊博, 横田秀夫, 大久保喬平, 上村真生, 曽我公平. 小動物3次元近赤外蛍光イメージングにおける屈折の抑制, 第29回日本バイオイメージング学会学術集会, バイオイメージング, Vol. 29, Issue 1, p. 49, Nov. 2020.
• 宮田敬充, 梅澤雅和, 野村洸希, 大久保喬平, 世良俊博, 横田秀夫, 曽我公平. 近赤外蛍光タイムゲートCTを用いた蛍光寿命の断層画像法による多色3次元イメージング, 第29回日本バイオイメージング学会学術集会, バイオイメージング, Vol. 29, Issue 1, p. 46, Nov. 2020.
• 北川雄一, 大久保喬平, 梅澤雅和, 上村真生, 大谷 直子, 曽我公平. Visualization of quantitative lipid distribution in mouse livers using near-infrared hyperspectral imaging, 第29回日本バイオイメージング学会, Nov. 2020.
• 手塚景子, 梅澤雅和, Tei-I Liu, 野村洸希, 大久保喬平, Hsin-Cheng Chiu, 上村真生, 曽我公平. Hybrid nanostructure of ultrasmall Yb/Er doped beta-NaYF4 nanoparticles with hydrocarbonized rose bengal for NIR-induced photodynamic therapy, 第29回日本バイオイメージング学会, Nov. 2020.
• 佐藤大幹, 細川直輝, 前田耕輔, 高松利寛, 大久保喬平, 梅澤雅和, 上村真生, 横田秀夫, 竹村裕, 桑田健, 池松弘朗, 矢野 友規, 曽我公平. 近赤外ハイパースクペクトルイメージング内視鏡の開発にむけて, 日本消化管学会, 日本消化管学会雑誌, Vol. 3, Supplement, p. 113, Feb. 2019.

[ BibTeX 形式で保存 ]    [ 論文・著書をCSV形式で保存 ]    [ 特許をCSV形式で保存 ]