@article{CTT100875112, author = {Keijun Kakihara and Kengo Asamizu and Kei Moritsugu and Masahide Kubo and Tetsuya Kitaguchi and Akinori Endo and Akinori Kidera and Mitsunori Ikeguchi and Akira Kato and Masayuki Komada and Toshiaki Fukushima.}, title = {Molecular basis of ubiquitin-specific protease 8 autoinhibition by the WW-like domain.}, journal = {Commun Biol}, year = 2021, } @inproceedings{CTT100898133, author = {Keijun Kakihara and Masayuki Komada and Toshiaki Fukushima}, title = {Caspase-dependent STAMBPL1 cleavage promotes cell death through its C-terminal fragment with hyperactive deubiquitinating activity}, booktitle = {}, year = 2023, } @inproceedings{CTT100918036, author = {安藤 凱 and 森次 圭 and 木寺 詔紀 and 柿原 慧遵 and 駒田 雅之 and 福嶋 俊明}, title = {脱ユビキチン化酵素USP48の活性制御機構とクッシング病関連変異による制御異常}, booktitle = {}, year = 2023, } @inproceedings{CTT100918035, author = {萩生田 健太 and 氷見 雄哉 and 柿原 慧遵 and 駒田 雅之 and 福嶋 俊明}, title = {ユビキチン化依存的なGagとALIXの相互作用によってレンチウイルスRNAのウイルス粒子への取り込みが促進される}, booktitle = {}, year = 2023, } @inproceedings{CTT100898129, author = {Keijun Kakihara and Masayuki Komada and Toshiaki Fukushima}, title = {Cis-activity regulation of USP8 and STAMBPL1, two endosomal deubiquitinating enzymes, and role of dysregulation in disease onset}, booktitle = {}, year = 2022, } @inproceedings{CTT100898131, author = {Gai Ando and Keijun Kakihara and Masayuki Komada and Toshiaki Fukushima}, title = {Molecular mechanisms underlying the over-activation of USP8 and USP48 by Cushing’s disease-associated mutations}, booktitle = {}, year = 2022, } @inproceedings{CTT100898138, author = {福嶋 俊明 and 柿原 慧遵 and 浅水 謙吾 and 森次 圭 and 北口 哲也 and 駒田 雅之}, title = {クッシング病を引き起こすUSP8の過剰活性化機構}, booktitle = {第95回日本生化学会大会要旨集}, year = 2022, } @inproceedings{CTT100898134, author = {西岡 柚香 and 柿原 慧遵 and 遠藤 彬則 and 駒田 雅之 and 福嶋 俊明}, title = {脱ユビキチン化酵素USP8によるVAMP8の制御とその細胞質分裂における意義の解明}, booktitle = {}, year = 2022, } @inproceedings{CTT100898141, author = {Keijun Kakihara and Kei Moritsugu and Tetsuya Kitaguchi and Akinori Endo and Masayuki Komada and Toshiaki Fukushima}, title = {Autoinhibition of USP8 by WW-like domain and the dysregulation in Cushing’s disease}, booktitle = {EMBO Workshop “Ubiquitin and ubiquitin-like proteins in health and disease”}, year = 2022, } @inproceedings{CTT100898140, author = {福嶋 俊明 and 柿原 慧遵 and 駒田 雅之}, title = {脱ユビキチン化酵素USP8の遺伝子変異を介したクッシング病の発症メカニズム}, booktitle = {}, year = 2022, } @inproceedings{CTT100875547, author = {氷見 雄哉 and 柿原 慧遵 and 加藤 明 and 駒田 雅之 and 福嶋 俊明}, title = {脱ユビキチン酵素USP8はレンチウイルス粒子へのウイルスRNAの動員を阻害することによってウイルスの増殖を防ぐ}, booktitle = {}, year = 2021, } @inproceedings{CTT100875225, author = {柿原慧遵 and 浅水謙吾 and 森次圭 and 北口哲也 and 遠藤彬則 and 木寺詔記 and 池口満徳 and 駒田雅之 and 福嶋俊明}, title = {脱ユビキチン化酵素USP8の自己阻害機構とクッシング病関連変異によるその解除}, booktitle = {第44回日本分子生物学会年会要旨集}, year = 2021, } @inproceedings{CTT100813515, author = {Keijun Kakihara and Kengo Asamizu and Akinori Endo and Kei Moritsugu and Akira Kato and Masayuki Komada and Toshiaki Fukushima}, title = {The enzyme activity of USP8 is regulated by the intramolecular interaction of the USP domain and the WW domain}, booktitle = {}, year = 2019, } @inproceedings{CTT100813519, author = {Keijun Kakihara and Kengo Asamizu and Akinori Endo and Masayuki Komada and Toshiaki Fukushima}, title = {A novel autoinhibitory mechanism of ubiquitin-specific protease 8 activity via the intramolecular interaction}, booktitle = {}, year = 2019, } @inproceedings{CTT100813525, author = {Keijun Kakihara and Kengo Asamizu and Akinori Endo and Masayuki Komada and Toshiaki Fukushima}, title = {A novel autoinhibitory mechanism of ubiquitin-specific protease 8 activity via the intramolecular interaction}, booktitle = {}, year = 2019, } @inproceedings{CTT100813526, author = {柿原 慧遵 and 浅水 謙吾 and 遠藤 彬則 and 駒田 雅之 and 福嶋 俊明}, title = {脱ユビキチン化酵素 USP8 の自己活性抑制機構}, booktitle = {}, year = 2019, } @inproceedings{CTT100813529, author = {柿原慧遵 and 浅水謙吾 and 遠藤彬則 and 駒田雅之 and 福嶋俊明}, title = {脱ユビキチン化酵素USP8の自己活性抑制機構}, booktitle = {}, year = 2019, } @misc{CTT100853023, author = {Keijun Kakihara and Kengo Asamizu and Kei Moritsugu and Masahide Kubo and Tetsuya Kitaguchi and Akinori Endo and Akinori Kidera and Mitsunori Ikeguchi and Akira Kato and Masayuki Komada and Toshiaki Fukushima}, title = {The molecular basis of ubiquitin-specific protease 8 autoinhibition by the WW-like domain}, year = 2021, } @misc{CTT100886440, author = {Keijun Kakihara}, title = {Cis-regulations of USP8 and STAMBPL1 deubiquitinases and their pathophysiological roles}, year = 2023, } @misc{CTT100886439, author = {Keijun Kakihara}, title = {Cis-regulations of USP8 and STAMBPL1 deubiquitinases and their pathophysiological roles}, year = 2023, } @misc{CTT100910899, author = {Keijun Kakihara}, title = {Cis-regulations of USP8 and STAMBPL1 deubiquitinases and their pathophysiological roles}, year = 2023, } @phdthesis{CTT100886440, author = {Keijun Kakihara}, title = {Cis-regulations of USP8 and STAMBPL1 deubiquitinases and their pathophysiological roles}, school = {東京工業大学}, year = 2023, } @phdthesis{CTT100886439, author = {Keijun Kakihara}, title = {Cis-regulations of USP8 and STAMBPL1 deubiquitinases and their pathophysiological roles}, school = {東京工業大学}, year = 2023, } @phdthesis{CTT100910899, author = {Keijun Kakihara}, title = {Cis-regulations of USP8 and STAMBPL1 deubiquitinases and their pathophysiological roles}, school = {東京工業大学}, year = 2023, }