論文

• Tatsuya Onishi, Sachiko Matsuda, Yuki Nakamura, Junko Kuramoto, Akinori Tsuruma, Satoshi Sakamoto, Shunichi Suzuki, Daiichiro Fuchimoto, Akira Onishi, Shinichi Chikaki, Miki Kaneko, Akihiro Kuwahata, Masaki Sekino, Hiroshi Yasuno, Naohiro Hanyu, Tomoko Kurita, Hiroyuki Takei, Takashi Sakatani, Kanae Taruno, Seigo NakamuraTetsu Hayashida, Hiromitsu Jinno, Moriaki Kusakabe, Hiroshi Handa, Kaori Kameyama, Yuukou Kitagawa. Magnetically-promoted rapid immunofluorescence staining for frozen tissue sections., J. Histochem. Cytochem., vol. 67, p. 575-587, Apr. 2019.
• Kimura A., Kitajima, M., Nishida, K., Serada, S., Fujimoto, M., Naka, T., Fujii-Kuriyama, Y., Satoshi Sakamoto, Takumi Ito, HIROSHI HANDA, Tanaka, T., Yoshimura, A, Suzuki, H.. NQO1 inhibits TLR-dependent production of selective cytokines by promoting PDLIM2-mediated degradation of IkB-z, J. Exp. Med., Vol. 215, No. 8, p. 2197-2209, June 2018.
• Tomoyuki Mori, Takumi Ito, Shujie Liu, Hideki Ando, Satoshi Sakamoto, Yuki Yamaguchi, Etsuko Tokunaga, Norio Shibata, Hiroshi Handa. Structural basis of thalidomide enantiomer binding to cereblon, Scientific Reports, 8, 1, 1294, Jan. 2018.
• Yasuaki Kabe, Takanori Nakane, Ikko Koike, Tatsuya Yamamoto, Yuki Sugiura, Erisa Harada, Kenji Sugase, Tatsuro Shimamura, Mitsuyo Ohmura, Kazumi Muraoka, Ayumi Yamamoto, Takeshi Uchida, So Iwata, Yuki Yamaguchi, Elena Krayukhina, Masanori Noda, Hiroshi Handa, Koichiro Ishimori, Susumu Uchiyama, Takuya Kobayashi, Makoto Suematsu. Haem-dependent dimerization of PGRMC1/sigma-2 receptor facilitates cancer proliferation and chemoresistance, Nat. Commun., Vol. 7, pp. 11030, Mar. 2016.
• Pérez-Perarnau, A., Preciado, S., Palmeri, C. M., Moncunill-Massaguer, C., Iglesias-Serret, D., González-Gironès, D. M., Miguel, M., Satoki Karasawa, Sakamoto, S, Cosialls, A. M., Rubio-Patiño, C., Saura-Esteller, J., Ramón, R., Caja, L., Fabregat, I., Pons, G., HIROSHI HANDA, Albericio, F., Gil, J., Lavilla, R.. A trifluorinated thiazoline scaffold leading to pro-apoptotic agents targeting prohibitins, Angew. Chem. Int. Ed., Vol. 53, p. 10150-10154, Sept. 2014.
• Junichi Yamamoto, Yuri Hagiwara, Kunitoshi Chiba, Tomoyasu Isobe, Takashi Narita, Hiroshi Handa, Yuki Yamaguchi. DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes., Nat. Commun., Vol. 5, pp. 4263, June 2014.
• Misao Takemoto, Yumi Kawamura, Mikako Hirohama, Yuki Yamaguchi, Hiroshi Handa, Hisato Saitoh, Yoichi Nakao, Manabu Kawada, Khan Khalid, Hiroyuki Koshino, Ken-ichi Kimura, Akihiro Ito, Minoru Yoshida. Inhibition of protein SUMOylation by davidiin, an ellagitannin from Davidia involucrata, J. Antibiot., Vol. 67, No. 4, pp. 335-338, Apr. 2014.
• Satoshi Sakamoto, Kenshi Omagari, Yoshinori Kita, Yusuke Mochizuki, Yasuyuki Naito, Shintaro Kawata, Sachiko Matsuda, Osamu Itano, Hiromitsu Jinno, Hiroya Takeuchi, Yuki Yamaguchi, Yuko Kitagawa, Hiroshi Handa. Magnetically Promoted Rapid Immunoreactions Using Functionalized Fluorescent Magnetic Beads: A Proof of Principle, Clinical Chemistry, American Association for Clinical Chemistry, Vol. 60, No. 4, pp. 610-620, Jan. 2014.
• Shuji Iida, Kensuke Imai, Sachiko Matsuda, Osamu Itano, Mamoru Hatakeyama, Satoshi Sakamoto, Daisuke Kokuryo, Koji Okabayashi, Takashi Endo, Yoshiyuki Ishii, Hirotoshi Hasegawa, Ichio Aoki, Hiroshi Handa, Yuko Kitagawa. In vivo identification of sentinel lymph nodes using MRI and size-controlled and monodispersed magnetite nanoparticles, Journal of Magnetic Resonance Imaging, Vol. 38, No. 6, pp. 1346–1355, Nov. 2013.
• Hitomi Miyazaki, Ken Higashimoto, Yukari Yada, Takaho A. Endo, Jafar Sharif, Toshiharu Komori, Masashi Matsuda, Yoko Koseki, Manabu Nakayama, Hidenobu Soejima, Hiroshi Handa, Haruhiko Koseki, Susumu Hirose, Kenichi Nishioka. Ash1l Methylates Lys36 of Histone H3 Independently of Transcriptional Elongation to Counteract Polycomb Silencing, PLoS Genet, Vol. 9, No. 11, p. e1003897, Nov. 2013.
• Vipul Gupta, Shujie Liu, Hideki Ando, Ryohei Ishii, Shumpei Tateno, Yuki Kaneko, Masato Yugami, Satoshi Sakamoto, Yuki Yamaguchi, Osamu Nureki, Hiroshi Handa. Salicylic acid induces mitochondrial injury by inhibiting ferrochelatase heme biosynthesis activity, Mol. Pharmacol., Vol. 84, No. 6, pp. 824-833, Nov. 2013.
• Kaoru Ohno, Jun-ichi Sawada, Shigeharu Takiya, Mai Kimoto, Akiko Matsumoto, Takuya Tsubota, Keiro Uchino, Chi-chung Hui, Hideki Sezutsu, Hiroshi Handa, Yoshiaki Suzuki. Silk Gland Factor-2, Involved in Fibroin Gene Transcription, Consists of LIM Homeodomain, LIM-interacting, and Single-stranded DNA-binding Proteins, J. biol. chem, Vol. 288, pp. 31581-31591, Nov. 2013.
• Teruya Enomoto, Masa-aki Kawano, Hajime Fukuda, Wataru Sawada, Takamasa Inoue, Kok Chee Haw, Yoshinori Kita, Satoshi Sakamoto, Yuki Yamaguchi, Takeshi Imai, Mamoru Hatakeyama, Shigeyoshi Saito, Adarsh Sandhu, Masanori Matsui, Ichio Aoki, Hiroshi Handa. Viral protein-coating of magnetic nanoparticles using simian virus 40 VP1, J. Biotechnol., Vol. 167, No. 1, pp. 8-15, Aug. 2013.
• Teruya Enomoto, Masaaki Kawano, Hajime Fukuda, Wataru Sawada, Takamasa Inoue, Kok Chee Haw, Yoshinori Kita, Satoshi Sakamoto, Takeshi Imai, Mamoru Hatakeyama, Shigeyoshi Saito, Adarsh Sandhu, Masanori Matsui, Ichio Aoki, Hiroshi Handa. Viral protein-coating of magnetic nanoparticles using simian virus 40 VP1, Journal of Biotechnology, Vol. 167, No. 1, pp. 8-15, Aug. 2013.
• Jinsuk Kang, Zuolian Shen, Jae-Min Lim, Hiroshi Handa, Lance Wells, Dean Tantin. Regulation of Oct1/Pou2f1 transcription activity by O-GlcNAcylation, The FASEB Journal, Vol. 27, No. 7, pp. 2807-2817, July 2013.
• Kentaro Hotta, Akihiro Nashimoto, Eiji Yasumura, Masafumi Suzuki, Motoki Azuma, Yosuke Iizumi, Daisuke Shima, Ryusuke Nabeshima, Masaki Hiramoto, Akira Okada, Kumiko Sakata-Sogawa, Makio Tokunaga, Takumi Ito, Hideki Ando, Satoshi Sakamoto, Yasuaki Kabe, Shinichi Aizawa, Takeshi Imai, Yuki Yamaguchi, Hajime Watanabe, Hiroshi Handa. Vesnarinone suppresses TNFα mRNA expression by inhibiting valosin-containing protein, Mol. Pharmacol., Vol. 83, No. 5, pp. 930-938, May 2013.
• Jeff Kershaw, Christoph Leuze, Ichio Aoki, Takayuki Obata, Iwao Kanno, Hiroshi Ito, Yuki Yamaguchi, Hiroshi Handa. Systematic changes to the apparent diffusion tensor of in vivo rat brain measured with an oscillating-gradient spin-echo sequence, Neuroimage, Vol. 70, pp. 10-20, Apr. 2013.
• Satoki Karasawa, Motoki Azuma, Takeshi Kasama, Satoshi Sakamoto, Yasuaki Kabe, Takeshi Imai, Yuki Yamaguchi, Keisuke Miyazawa, Hiroshi Handa. Vitamin K2 Covalently Binds to Bak and Induces Bak-Mediated Apoptosis, Molecular Pharmacology, Vol. 83, No. 3, pp. 613-620, Mar. 2013.
• Masaaki Kawano, Masanori Matsui, Hiroshi Handa. SV40 virus-like particles as an effective delivery system and its application to a vaccine carrier, Expert Review of Vaccines, Vol. 12, No. 2, pp. 199-210, Feb. 2013.
• Yuki Yamaguchi, Hirotaka Shibata, Hiroshi Handa. Transcription elongation factors DSIF and NELF: Promoter-proximal pausing and beyond, Biochimica et Biophysica Acta. Gene Regulatory Mechanisms, Vol. 1829, No. 1, pp. 98-104, Jan. 2013.
• Tadashi Wada, Masatoshi Hara, Takuya Taneda, Cao Qingfu, Ryouhei Takata, Kanako Moro, Kei Takeda, Takeo Kishimoto, Hiroshi Handa. Antisense morpholino targeting just upstream from a poly(A) tail junction of maternal mRNA removes the tail and inhibits translation, Nucleic Acids Res., Vol. 40, No. 22, p. e173, Dec. 2012.
• Yuki Ito, Takumi Ito, Satoki Karasawa, Teruya Enomoto, Nashimoto, Akihiro, Hase, Yasuyoshi, Sakamoto, Satoshi, Mimori, Tsuneyo, Yoshihisa Matsumoto, Yuki Yamaguchi, HIROSHI HANDA. Identification of DNA-Dependent Protein Kinase Catalytic Subunit (DNA-PKcs) as a Novel Target of Bisphenol A, Plos One, Vol. 7, No. 12, p. e50481, Dec. 2012.  公式リンク  
  
• Lopez-Girona, Mendy D, Ito T, Miller K, Gandhi AK, Kang J, Karasawa S, Carmel G, Jackson P, Abbasian M, Mahmoudi A, Cathers B, Rychak E, Gaidarova S, Chen R, Schafer PH, Handa H, Daniel TO, Evans JF, Chopra R.. Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide, Leukemia, Vol. 26, No. 11, pp. 2326-2335, Nov. 2012.
• Gil Diamant, Liat Amir-Zilberstein, Yuki Yamaguchi, Hiroshi Handa, Rivka Dikstein. DSIF Restricts NF-κB Signaling by Coordinating Elongation with mRNA Processing of Negative Feedback Genes, Cell Reports, Vol. 2, No. 4, pp. 722–731, Oct. 2012.
• Satoshi Sakamoto, Mamoru Hatakeyama, Takumi Ito, Hiroshi Handa. Tools and methodologies capable of isolating and identifying a target molecule for a bioactive compound, Bioorganic & Medicinal Chemistry, Vol. 20, No. 6, pp. 1990–2001, Mar. 2012.
• Emiko Okuda-Ashitaka, Toshiaki Minami, Shingo Tsubouchi, Hiroshi Kiyonari, Akihiro Iwamatsu, Tetsuo Noda, Hiroshi Handa, Seiji Ito. Identification of NIPSNAP1 as a nocistatin-interacting protein involving pain transmission, J Biol Chem, Vol. 287, No. 13, pp. 10403-10413, Mar. 2012.
• HIROSHI HANDA, Takumi Ito. Deciphering the mystery of thalidomide teratogenicity, Congenital Anomalies, Vol. 52, No. 1, pp. 1-7, Mar. 2012.
• 74. M. ABE, T. UEDA, T. MASAKI, Y. KITAMOTO, N. MATSUSHITA, H. HANDA. Detecting Ferrite Nanobeads for Sentinel Lymph Node Mapping with a Highly Sensitive Hall Differential Magnetic Field Sensor, Asia-PacificInterdisciplinaryResearchConference2011(AP-IRC2011), Journal of physics : conference series, Vol. 352, 012015, Jan. 2012.
• Teruya Enomoto, Iwao Kukimoto, Masa-aki Kawano, Yuki Yamaguchi, Arnold J. Berk, Hiroshi Handa. In vitro reconstitution of SV40 particles that are composed of VP1/2/3 capsid proteins and nucleosomal DNA and direct efficient gene transfer, Virology, Vol. 420, No. 1, pp. 1-9, Nov. 2011.
• Yuichi Kitai, Hajime Fukuda, Teruya Enomoto, Yuki Asakawa, Takahiro Suzuki, Satoshi Inouye, Hiroshi Handa. Cell selective targeting of a simian virus 40 virus-like particle conjugated to epidermal growth factor, Journal of Biotechnology, Vol. 155, No. 2, pp. 251–256, Sept. 2011.
• Ayako Yasuma, Toyoko Ochiai, Motoki Azuma, Hiroyuki Nishiyama, Ken Kikuchi, Masao Kondo, Hiroshi Handa. Exogenous coproporphyrin III production by Corynebacterium aurimucosum and Microbacterium oxydans in erythrasma lesions, J. Med. Microbiol., Vol. 60, Pt.7, pp. 1038-1042, July 2011.
• Miho Aizawa, Yuichi Abe, Takumi Ito, Hiroshi Handa, Hiroyuki Nawa. mRNA distribution of the thalidomide binding protein cereblon in adult mouse brain, Neuroscience Research, Vol. 69, No. 4, pp. 343–347, Apr. 2011.
• Naoya Maekawa, Masaki Hiramoto, Satoshi Sakamoto, Motoki Azuma, Takumi Ito, Marie Ikeda, Michitaka Naitou, Hukum P. Acharya, Yuichi Kobayashi, Makoto Suematsu, Hiroshi Handa, Takeshi Imai. High-performance affinity purification for identification of 15-deoxy-Δ^12,14-PGJ₂ interacting factors using magnetic nanobeads, Biomedical Chromatography, Vol. 25, No. 4, pp. 466–471, Apr. 2011.
• Ayumi Kawano, Yohei Hayashi, Shuhei Noguchi, Hiroshi Handa, Masami Horikoshi, Yuki Yamaguchi. Global analysis for functional residues of histone variant Htz1 using the comprehensive point mutant library, Genes Cells, Vol. 16, No. 5, pp. 590-607, Mar. 2011.
• Takumi Ito, Hideki Ando, Hiroshi Handa. Teratogenic effects of thalidomide: molecular mechanisms, Cellular and Molecular Life Sciences, Vol. 68, No. 9, pp. 1569-1579, Mar. 2011.
• Mamoru Hatakeyama, Hiroshi Kishi, Yoshinori Kita, Kensuke Imai, Kosuke Nishio, Satoki Karasawa, Yuka Masaike, Satoshi Sakamoto, Adarsh Sandhu, Akihiro Tanimoto, Tatsuya Gomi, Eiichi Kohda, Masanori Abe, Hiroshi Handa. A two-step ligand exchange reaction generates highly water-dispersed magnetic nanoparticles for biomedical applications, Journal of Materials Chemistry, Vol. 21, No. 16, pp. 5959-5966, Mar. 2011.
• Takuya Taneda, Wenyan Zhu, Qingfu Cao, Hajime Watanabe, Yuki Yamaguchi, Hiroshi Handa, Tadashi Wada. Erythropoiesis is regulated by the transcription elongation factor Foggy/Spt5 through gata1 gene regulation, Genes to Cells, 16, 2, 231–242, Feb. 2011.
• Adarsh Sandhu, Hiroshi Handa, Masanori Abe. Synthesis and applications of magnetic nanoparticles for biorecognition and point of care medical diagnostics, Nanotechnology, Vol. 21, No. 44, pp. 442001-442022, Nov. 2010.
• Kunitoshi Chiba, Junichi Yamamoto, Yuki Yamaguchi, Hiroshi Handa. Promoter-proximal pausing and its release: molecular mechanisms and physiological functions, Exp. Cell Res., Vol. 316, No. 17, p. 2723-2730, Oct. 2010.
• Sol Kim, Junichi Yamamoto, Yexi Chen, Masatoshi Aida, Tadashi Wada, Hiroshi Handa, Yuki Yamaguchi. Evidence that cleavage factor Im is a heterotetrameric protein complex controlling alternative polyadenylation, Genes Cells, Vol. 15, No. 9, p. 1003-1013, Sept. 2010.
• Masaki Hiramoto, Naoya Maekawa, Takeshi Kuge, Fumiaki Ayabe, Atsushi Watanabe, Yuka Masaike, Mamoru Hatakeyama, Hiroshi Handa, Takeshi Imai. High-performance affinity chromatography method for identification of L-arginine interacting factors using magnetic nanobeads, Biomedical Chromatography, Vol. 24, No. 6, pp. 606–612, June 2010.
• Aiko Tominaga, Hideki Sugawara, Toshitaka Futagawa, Kazuhiko Inoue, Kazuki Sasaki, Naoto Minamino, Mamoru Hatakeyama, Hiroshi Handa, Atsuro Miyata. Characterization of the testis-specific promoter region in the human pituitary adenylate cyclase-activating polypeptide (PACAP) gene, Genes to Cells, Vol. 15, No. 6, pp. 595–606, June 2010.
• Sang Yoon Park, Pil Joo Ko, Hiroshi Handa, Adarsh Sandhu. Exploring magneto-optical properties of biofunctionalized magnetic chains for developing label-free immunoassays, Journal of Applied Physics, Vol. 107, No. 9, Page 09B324, May 2010.
• Kanako Kume, Yosuke Iizumi, Masashi Shimada, Yuki Ito, Tsutomu Kishi, Yuki Yamaguchi, Hiroshi Handa. Role of N-end rule ubiquitin ligases UBR1 and UBR2 in regulating the leucine-mTOR signaling pathway, Genes Cells, Vol. 15, No. 4, p. 339-349, Apr. 2010.
• Yoshitaka Morimoto, Tsukasa Takamura, Sang Yoon Park, Satoshi Sakamoto, Shintaro Kawata, Hiroshi Handa, Adarsh Sandhu. Detection of 8 nm Diameter Superparamagnetic Beads by Magnetically-Induced Manipulation of Micrometer-Sized Magnetic Beads: A Novel Protocol for Magnetically-Labeled Biosensing, Japanese Journal of Applied Physics, Vol. 49, Page 04DL07, Apr. 2010.
• Takumi Ito, Hideki Ando, Takayuki Suzuki, Toshihiko Ogura, Kentaro Hotta, Yoshimasa Imamura, Yuki Yamaguchi, Hiroshi Handa. Identification of a primary target of thalidomide teratogenicity, Science, Vol. 327, No. 5971, p. 1345-1350, Mar. 2010.
• Yuka Masaike, Takeshi Takagi, Masataka Hirota, Joe Yamada, Satoru Ishihara, Tetsu M. C. Yung, Takamasa Inoue, Chika Sawa, Hiroshi Sagara, Satoshi Sakamoto, Yasuyuki Takahashi, Yuki Yamaguchi, Hiroshi Handa, Yasuaki Kabe. Identification of Dynamin-2-Mediated Endocytosis as a New Target of Osteoporosis Drugs, Bisphosphonates, Molecular Pharmacology, Vol. 77, No. 2, pp. 262-269, Feb. 2010.
• Sang Yoon Park, Hiroshi Handa, Adarsh Sandhu. Magneto-Optical Biosensing Platform Based on Light Scattering from Self-Assembled Chains of Functionalized Rotating Magnetic Beads, NANO LETT., Vol. 10, No. 2, pp. 446–451, Feb. 2010.
• Yexi Chen, Yuki Yamaguchi, Yuta Tsugeno, Junichi Yamamoto, Tomoko Yamada, Mitsuhiro Nakamura, Koji Hisatake, Hiroshi Handa. DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation, Genes Dev., 23, 23, 2765-2777, Dec. 2009.
• Hui Chen, Xavier Contreras, Yuki Yamaguchi, Hiroshi Handa, B. Matija Peterlin, Su Guo. Repression of RNA Polymerase II elongation in vivo is critically dependent on the C-terminus of Spt5, PLoS ONE, Vol. 4, No. 9, p. e6918, Sept. 2009.
• Tetsu M. C. Yung, Takashi Narita, Toshiharu Komori, Yuki Yamaguchi, Hiroshi Handa. Cellular dynamics of the negative transcription elongation factor NELF, Exp. Cell Res., 315, 10, 1693-1705, June 2009.
• Hiroyuki Kamiya, Akihiro Suzuki, Yuki Yamaguchi, Hiroshi Handa, Hideyoshi Harashima. Incorporation of 8-hydroxyguanosine (8-oxo-7,8-dihydroguanosine) 5'-triphosphate by bacterial and human RNA polymerases, Free Radic. Biol. Med., 46, 12, 1703-1707, June 2009.
• Chikanori Kuramori, Yasuyoshi Hase, Koichi Hoshikawa, Keiko Watanabe, Takeyuki Nishi, Takako Hishiki, Tomoyoshi Soga, Akihiro Nashimoto, Yasuaki Kabe, Yuki Yamaguchi, Hajime Watanabe, Kohsuke Kataoka, Makoto Suematsu, Hiroshi Handa. Mono-(2-ethylhexyl) phthalate targets glycogen debranching enzyme and affects glycogen metabolism in rat testis, Toxicol. Sci., 109, 1, 143-151, May 2009.
• Toshiharu Komori, Naoto Inukai, Tomoko Yamada, Yuki Yamaguchi, Hiroshi Handa. Role of human transcription elongation factor DSIF in the suppression of senescence and apoptosis, Genes Cells, 14, 3, 343-354, Mar. 2009.
• Chikanori Kuramori, Motoki Azuma, Kanako Kume, Yuki Kaneko, Atsushi Inoue, Yuki Yamaguchi, Yasuaki Kabe, Takamitsu Hosoya, Masahiro Kizaki, Makoto Suematsu, Hiroshi Handa. Capsaicin binds to prohibitin 2 and displaces it from the mitochondria to the nucleus, Biochem. Biophys. Res. Commun., 379, 2, 519-525, Feb. 2009.
• HIROSHI HANDA. Preparation of spherical and uniform-sized ferrite nanoparticles with diameters between 50-150 nm for biomedical applications., J.Magn. Magn. Mater, Vol. 321, No. 10, pp. 1417-1420, 2009.
• Satoshi Sakamoto, Yasuaki Kabe, Mamoru Hatakeyama, Yuki Yamaguchi, Hiroshi Handa. Development and application of high-performance affinity beads: toward chemical biology and drug discovery, Chem. Rec., 9, 1, 66-85, 2009.
• Kozue Ando, Satoshi Hirao, Yasuaki Kabe, Yuji Ogura, Iwao Sato, Yuki Yamaguchi, Tadashi Wada, Hiroshi Handa. A new APE1/Ref-1-dependent pathway leading to reduction of NF-kappaB and AP-1, and activation of their DNA-binding activity, Nucleic Acids Res., 36, 13, 4327-4336, Aug. 2008.
• Motoki Azuma, Yasuaki Kabe, Chikanori Kuramori, Masao Kondo, Yuki Yamaguchi, Hiroshi Handa. Adenine nucleotide translocator transports haem precursors into mitochondria, PLoS One, 3, 8, e3070, Aug. 2008.
• Ryou-u Takahashi, Shin-nosuke Kanesashi, Takamasa Inoue, Teruya Enomoto, Masa-aki Kawano, Hiroko Tsukamoto, Fumitaka Takeshita, Takeshi Imai, Takahiro Ochiya, Kohsuke Kataoka, Yuki Yamaguchi, Hiroshi Handa. Presentation of functional foreign peptides on the surface of SV40 virus-like particles, J. Biotechnol., 135, 4, 385-392, July 2008.
• Masafumi Suzuki, Shoichiro Furukawa, Chikanori Kuramori, Chika Sawa, Yasuaki Kabe, Mitsuhiro Nakamura, Jun-ichi Sawada, Yuki Yamaguchi, Satoshi Sakamoto, Satoshi Inouye, Hiroshi Handa. Development of a chemical screening system using aqueorin-fused protein, Biochem. Biophys. Res. Commun., 368, 3, 600-605, Apr. 2008.
• Matsushita Nobuhiro, Nakagawa Kazunori, Taniguchi Takaaki, Handa Hiroshi, Tada Masaru, Abe Masanori, Yoshimura Masahiro. Hundred-nanometer Sized Biomagnetic Beads with Large Magnetization Using Ferrite Nanoparticles Grown by Hydrothermal Process, Journal of Applied Physics, Volume 103, No. 7, p. 07A317, Apr. 2008.
• Takashi Narita, Yung, T.M.C., Junichi Yamamoto, Tsuboi, Y., Tanabe, H., Tanaka, K., Yamaguchi, Y., HIROSHI HANDA, , . NELF interacts with CBC and participates in 3'-end processing of replication-dependent histone mRNAs, Mol. Cell, Vol. 26, No. 3, pp. 349-365, May 2007.
• K. Nishio, M. Ikeda, N. Gokon, S. Tsubouchi, H. Narimatsu, Y. Mochizuki, S. Sakamoto, A. Sandhu, M. Abe, H. Handa. Preparation of size-controlled (30-100nm) magnetite nanoparticles for biomedical applications., J. Magn. Magn. Mater., Vol. 310, pp. 2408-2410, 2007.
• Adarsh Sandhu, Yoshimich Kumagai, Adam Lapicki, Satoshi Sakamoto, Masanori Abe, Hiroshi Handa. High efficiency Hall effect micro-biosensor platform for detection of magnetically labeled biomolecules, Biosensors & Bioelectronics, Vol. 2, No. 9-10, pp. 2115-2120, 2007.
• Hitoshi Uga, Chikanori Kuramori, Akiko Ohta, Yasunori Tsuboi, Hiroshi Tanaka, Mamoru Hatakeyama, Yuki Yamaguchi, Masahiro Kizaki, Takashi Takahashi, Hiroshi Handa. A new mechanism of methotrexate action revealed by target screening with affinity beads, Mol. Pharmacol., Vol. 70, No. 5, pp. 1832-1839, Aug. 2006.
• Hisakage Funabashi, Yasuhiro Tanaka, Yoshimasa Imamura, Masayasu Mie, Takashi Manabe, Hiroshi Tanaka, Takashi Takahashi, Hiroshi Handa, Masuo Aizawa, Eiry Kobatake. Glucose oxidase assisted homogeneous electrochemical receptor binding assay for drug screening, Biosens Bioelectron, Vol. 21, No. 9, pp. 1675-1683, June 2006.  公式リンク  
  
• Kusunoki, N., Ito, T., Sakurai, N., Handa, H., Kawai S.. A celecoxib derivative potently inhibits proliferation of colon adenocarcinoma cells by induction of apoptosis., Anticancer Res., Vol. 26, pp. 3229-3236, 2006.
• Kubo, T., Wada, T., Yamaguchi, Y., Shimizu, A., Handa, H.. Knock-down of 25-kDa Subunit of Cleavage Factor Im in HeLa Cells Alters Alternative Polyadenylation within 3’UTRs., Nucleic Acids Res., Vol. 34, pp. 6264-6271, 2006.
• Okawa, K., Sekine, M., Maeda, M., Tada, M., Abe, M., Matsushita, N., Nishio, K., Handa, H.. Heating ability of magnetite nanobeads with various sizes for magnetic hyperthermia at120kHz, a noninvasive frequency., J. Appl. Phys., Vol. 99, pp. 08H102, 2006.
• Maeda, M., Kuroda, S., Shimura, T., Tada, M., Abe, M., Yamamuro, S., Sumiyama, K., Handa, H.. Magnetic carriers of iron nanoparticles coated with a functional polymer for high thoughput bio-screening., J. Appl. Phys., Vol. 99, pp. 08H103, 2006.
• Togawa, K., Sanbonsugi, H., Sandhu, A., Narimatsu, H., Nishio, K., Handa, H.. Detection of magnetically labeled DNA using pseudomorphic AlGaAs/InGaAs/GaAs heterostructure micro-Hall biosensor., J. Appl. Phys., Vol. 99, pp. 08P103, 2006.
• Ogura, Y., Azuma, M., Tsuboi, Y., Kabe, Y., Yamaguchi, Y., Wada, T., Watanabe, H., Handa, H.. TFII-I down-regulates a subset of estrogen-responsive genes through its interaction with an initiator element and estrogen receptor alpha., Genes Cells., Vol. 11, pp. 373-381, 2006.
• Kawano, M., Inoue, T., Tsukamoto, H., Takaya, T., Enomoto, T., Takahashi, R. U., Yokoyama, N., Yamamoto, N., Nakanishi, A., Imai, T., Wada, T., Kataoka, K., Handa, H.. The VP2/VP3 minor capsid ptotein of SV40 promotes the in vitro assembly of the major capsid protein VP1 into particles., J. Biol. Chem., Vol. 281, pp. 10164-10173, 2006.
• Sakurai, N., Miki, Y., Suzuki, T, Watanabe, K., Narita, T., Ando, K., Young, T.C.Y., Aoki, D., Sasano, H., Handa, H.. Systemic Distribution and Tissue Localizations of Human 17beta-Hydroxysteroid Dehydrogenase Type 12., J. Steroid Biochem. Mol. Biol., Vol. 99, pp. 174-181, 2006.
• Aida, M., Chen, Y., Nakajima, K., Yamaguchi, Y., Wada, T., Handa, H.. Transcriptional pausing caused by NELF plays a dual role in regulating immediate-early expression of the junB gene., Mol. Cell. Biol., Vol. 26, pp. 6094-6104, 2006.
• Nishio, K., Gokon, N., Tsubouchi, S., Ikeda, M., Narimatsu, H., Sakamoto, S., Izumi, Y., Abe, M., Handa, H.. Direct Detection of Redox Reactions of Sulfur-containing Compounds on Ferrite Nanoparticle (FP) Surface., Chem. Lett., Vol. 35, pp. 974-975, 2006.
• Kabe, Y., Ohmori, M., Shinouchi, K., Tsuboi, Y., Hirao, S., Azuma, M., Watanabe, H., Okura, I., Handa, H.. Porphrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier., J. Biol. Chem., Vol. 281, pp. 31729-31735, 2006.
• Uga, H., Kuramori, C., Ohta, A., Tsuboi, Y., Tanaka, H., Hatakeyama, M., Yamaguchi, Y., Takahashi, T., Kizaki, M., Handa, H.. A new mechanism of methotrxate action revealed by target screening with affinity beads., Mol. Pharmacol., Vol. 70, pp. 1832-1839, 2006.
• Yamamoto, N., Suzuki, M., Kawano, M., Inoue, T., Takahashi, R., Tsukamoto, H., Enomoto, T., Yamaguchi, Y., Wada, T., Handa, H.. Adeno-associated virus site-specific integration is　regulated by TRP-185., J.Virol., Vol. 81, pp. 1990-2001, 2006.
• Yugami, M., Kabe, Y., Yamaguchi, Y., Wada, T., Handa, H.. hnRNP-U　enhances　the　expression　of　specific　genes by stabilizing mRNA., FEBS Lett., Vol. 581, pp. 1-7, 2006.
• Kumagai, Y., Togawa, K., Sakamoto, S., Abe, M., Handa, H., Sandhu, A.. Hall biosensor with integrated current microstrips for control of magnetic beads., IEEE Trans. Magn. Soc., Vol. 42, pp. 3803, 2006.
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• M.hiramoto, N.Shimizu, K.Sugimoto, J.Tang, K.Kawakami, M.Ito, S.Aizawa, H.Tanaka, I.Makino, H.Handa. Nuclear targetted suppression of NF-kB activity by the novel quinone derivative E3330., J.Immunol., Vol. 160, pp. 810-819, 1998.
• T.Wada, T.Takagi, Y.Yamaguchi, A.Ferdous, T.Imai, S.Hirose, S.Sugimoto, K.Yano, G.A.Hartog, F.winston, S.Buratowski, h.Handa. DSIF, a novel negative transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs., Genes Dev., No. 12, pp. 343-356, 1998.
• F.Hirano, H.Tanaka, Y.Hirano, M.hiramoto, H.Handa, I.Makino, C.Scheidereit. Functional interference of Sp1 and NF-kB through the same DNA binding site., Mol.Cell.Biol., No. 18, pp. 1266-1274, 1998.
• G.A.Hartog, T.Wada, H.Handa, F.winston. Evidence that Spt4, Spt5, and spt6 control transcription by RNA polymerase II in Saccharomyces cerevisiae., Genes Dev., Vol. 12, pp. 357-369, 1998.
• M.Hatakeyama, S.Iwato, K.Fujimoto, H.Handa, H.Kawaguchi. DNA-carrying latex particles for DNA diagnosis. 1. Separation of normal and point mutant DNAs according to the difference in hybridization efficiency, Colloids and Surfaces B: Biointerfaces, No. 10, pp. 8287-8293, 1998.
• M.Hatakeyama, K.Nakamura, S.Iwato, H.Handa, K.fujimoto, H.Kawaguchi. DNA-carrying latex particles for DNA diagnosis. 2. Distinction of normal and point mutant DNA using S1 nuclease., Colloid and Surfaces B: Biointerfaces, No. 10, pp. 3854-3861, 1998.
• HIROSHI HANDA. NAP-1 is a functional homologo of TAF-1 thet is required for replication and transcription of the adanovirus gonome in chromatin-like structure., Genes to Cells, Vol. 1, pp. 1045-1056, 1997.
• HIROSHI HANDA. Retinoblastoma binding factor I site in the core promoter region of the human RB gene is activated by hGABP/E4TF1., Cancer Res., Vol. 57, pp. 3145-3148, 1997.
• HIROSHI HANDA. Autoregnlation of pax6 transcriptianl activation by two distinct DNA-binding subdomains of the paired domain., Genes Cells, Vol. 2, pp. 255-261, 1997.
• HIROSHI HANDA. Molecular cloning of MBF2 reveals its contact with TFEA that leads to transcriptional activation., Genes Cells, Vol. 2, pp. 143-153, 1997.
• HIROSHI HANDA. Characterization of the human thrombopoietin gene promoter., J. Biol. Chem., Vol. 272, pp. 11361-11368, 1997.
• HIROSHI HANDA. Inhibition of HIV-I protease by oxim devivatives., Biochem. Biophys. Res. Commun., Vol. 230, pp. 557-561, 1997.
• HIROSHI HANDA. ERC-55, a binding protein for the papilloma virus E6 oncoprotein, specifically interacts with vitamin D receptor amony nuclear receptors, Biochem. Biophys. Res. Commun., Vol. 233, pp. 765-769, 1997.
• T.Komai, Y.Ishikawa, R.Yagi, H.Suzuki-Sugawara, T.Nishigaki, H.Handa. Possible involvement of bone marrow stromal cells in agranulocytosis caused by vesnarinone treatment , Acta Hematologica, Vol. 98, pp. 140-146, 1997.
• T.Komai, Y.Ishikawa, R.Yagi, H.Suzuki-Sugawara, T.Nishigaki, H.Handa. Development of HIV-1 protease expression methods using T7 phage promoter system , Appl. Microbiol. Biotechnol, Vol. 98, pp. 140-146, 1997.
• F.Momose, H.Handa, K.Nagata. Identification of host factors that regulate the influenza virus RNA polymerase activity , Biochimie, Vol. 78, pp. 1103-1108, 1997.
• HIROSHI HANDA. The promoter of the androgen dependent gene in the flank argan of Ramsters., J. Dermatol. Sci, Vol. 15, pp. 36-43, 1997.
• HIROSHI HANDA. Effects of vesnarinone on the bone marrow stromal cell-dependent proliferation and differentiation of HL60 cells in vitro., Exp. Hematol., Vol. 25, pp. 509-515, 1997.
• HIROSHI HANDA. Phosphorylation and high level oxpression of Fra-2 in v-src transformed cells : a pathway of activation of endogeneous AP-1., Oncogene, Vol. 14, pp. 2435-2444, 1997.
• 半田宏　共著, 田村隆明, 村松正美編 . 転写のメカニズムと疾患, 羊土社, 1997.
• 半田宏. 「タンパク質化学　第3巻」（遺伝情報の発現）, 廣川書店, 1997.
• 山口雄輝, 半田宏. 転写因子とウイルス「転写因子とその異常」, 中外医学社, Vol. 23, pp. 101-106, 1997.
• 半田宏. 分子細胞生物学辞典, 東京化学同人, 1997.
• HIROSHI HANDA. Promoter structure of the MxA gene that confers resistance to influenza virus., FEBS Lett., Vol. 418, pp. 315-318, 1997.
• HIROSHI HANDA. Preparation of dimerized polypeptido-carrying microspheres and purification of specific proteins bound to these microspheres, Colloids and Sunfaces B : Biointerfaces, Vol. 10, pp. 41-49, 1997.
• HIROSHI HANDA. Inhibition of H1V-1 protease by oxim devivatives, Biochem. Bioplys. Res. Commun., Vol. 230, pp. 557-561, 1997.
• HIROSHI HANDA. Mechanism for inhibition of influenza virus RNA polymeraso activity by matrix protein., J. Virol., Vol. 70, pp. 241-247, 1996.
• HIROSHI HANDA. Assignment of the E4TF1-60 gene, an Ets-related transcription factor, to human chromosome 21q21.2-q21.3., Gene, Vol. 166, pp. 337-338, 1996.
• HIROSHI HANDA. Selective purification of DNA or RNA using single-stranded DNA aftinity latex particles, J. Colloid Interface Sci., Vol. 177, pp. 245-249, 1996.
• HIROSHI HANDA. Copurification of casein kinase II with transcription factor ATF/E4TF3., Nucleic Acids Res., Vol. 24, pp. 876-884, 1996.
• HIROSHI HANDA. Activation of the retinoblastoma gene expression by Bcl-3 : lmplication for muscle cell differentiation., Oncogene, Vol. 12, pp. 1837-1845, 1996.
• HIROSHI HANDA. Atranscription factor with a leucine-zipper motit involved in light-depenclent inhibition of expression of the put operon in the photosynthotic bacterium phodobacter sphaeroides, Plant cell Pysiol., Vol. 37, pp. 515-522, 1996.
• HIROSHI HANDA. Purification and characterization of virus-like particles and pentamers produced by the expression of SV40 capsid proteins in insect cells., Biochim. Biophys. Acta., Vol. 1290, pp. 37-45, 1996.
• HIROSHI HANDA. Detection of amplified genomic sequences in human small-cell lung carcinoma cell lines by arbitrarily primed-PCR genomic fingerprinting., Human Genomis, Vol. 98, pp. 253-258, 1996.
• HIROSHI HANDA. Construction and characterization of a recombinant adenorirus vector carring the human preproinsulin gene under the control of the methallothionein gene promoter., Biochem. Biophys. Res. Commun., Vol. 229, pp. 778-787, 1996.
• HIROSHI HANDA. Functional domains of transcription factor hGABP β1/E4TF1-53 required for nuclear localization and transcription activation., Nucleic Acids Res., Vol. 24, pp. 4954-4961, 1996.
• M.Hashimoto, K.Chayama, A.Tsubota, M.Kobayashi, S.Saitou, Y.Arase, K.Ikeda, M.Kobayashi, A.Nakano, K.Takagi, H.Koike, K.Okamoto, H.Handa, H.Kumada . Typing six major hepatitis C virus genotypes by polymerase chain reaction using primers derived from nucleotide sequences of the NS5 region , Int. Hepatol. Commun, Vol. 4, pp. 263-267, 1996.
• F.Hirano, H.Tanaka, Y.Makino, K.Okamoto, M.Hiramoto, H.Handa, I.Makino . Induction of the transcription factor AP-1 in cultured human colon adenocarcinoma cells following exposure to bile acids , Carcinogenesis, Vol. 17, pp. 427-433, 1996.
• S.Inokuchi, H.Handa, T.Imai, H.Makuuchi, M.Kidokoro, H.Tohya, S.Aizawa, K.Shimamura, Y.Ueyama, T.Mitomi, Y.Sawada . Immortalization of human esophageal epithelial cells by a recombinant SV40-adenovirus vector , Br. J. Cancer, Vol. 71, 819-825, 1995.
• K.Araki-Sasaki, Y.Ohashi, T.Sasabe, K.Hayashi, H.Watanabe, Y.Tano, H.Handa . An SV40-immortalized human corneal epithelial cell line and its characterization. Invest , Ophthalmol. Vis. Sci, Vol. 36, pp. 614-621, 1995.
• Y.Zhang, K.Araki-Sasaki, H.Handa, R.A.Akhtar. Effect of carbachol on phospholipase C-mediated phosphatidylinositol 4,5-bisphosphate hydrolysis,and its modulation by isoproterenol in rabbit corneal epithelial cells , Curr. Eye Res , Vol. 14, pp. 563-571, 1995.
• K.Watanabe, F.Momose, H.Handa, K.Nagata. Interaction between influenza virus proteins and pine cone antitumor substance that inhibits the virus multiplication , Biochem. Biophys. Res. Commun, Vol. 224, pp. 318-323, 1995.
• M.Goto, T.Shimizu, J-I.Sawada, C.Sawa, H.Watanabe, H.Ichikawa, M.Ohira, M.Ohki, H.Handa . Assignment of the E4TF1-60 gene, an Ets-related transcription factor, to human chromosome 21q21.2-q21.3 , Gene, Vol. 166, pp. 337-338, 1995.
• 半田宏. 好みのタイプ, バイオサイエンスとバイオインダストリー, Vol. 53, pp. 731, 1995.
• 半田宏. 転写因子, 炎症と免疫, Vol. 3, pp. 108-110, 1995.
• HIROSHI HANDA. cDNA library for a specific region of chromosome by a novel cDNA selection method using latex porticles., Gene, Vol. 165, pp. 155-161, 1995.
• HIROSHI HANDA. Purification of membrane receptors with peptide-carring affinity latex beads., Colloids and Surfaces B : Biointerfaces, Vol. 4, pp. 231-241, 1995.
• HIROSHI HANDA. Potentiation of glucocorticoid-mediated gene expression by the novel benzoquinone derivative(2E)-3-[5-(2,3-dimethoxy-o-methyl-1,4-benzoquinoyl)]-2-nonyl-2-propenoic acid (E3330)., Eur. J. Pharm, Vol. 291, pp. 121-127, 1995.
• HIROSHI HANDA. Purification of transcription factor IIA using yeast TATA-binding protein affinity latex particles, International J. Bio-Chromatography, Vol. 1, pp. 191-198, 1995.
• HIROSHI HANDA. GABP and PU.I Compete for Binding ,Yet Cooperate to Increase CD18(β┣D22┫D2 Leukocyte Integrin) transcription, J.Biol.Chem, Vol. 270, pp. 23627-23633, 1995.
• HIROSHI HANDA. A Nuclear Factor (NF2d9) That Binds to the Male-Specific P450(Cyd 2d-9) Gare in Mouse Liver, Mol.Cell.Biol., Vol. 15, pp. 4158-4166, 1995.
• HIROSHI HANDA. Cell Type-Specihic Trans-Activation by the B-Myd Gene product:Repuirement of the Putative Cofactor Binding to the C-Terminal Consorved Domain, Oncogene, Vol. 10, pp. 1699-1707, 1995.
• HIROSHI HANDA. Stimulation of DNA Formscription by the Replication factor From the Adenovirus Genome in a Chromation-Like Structure, J.Biol.Chem, Vol. 270, pp. 9645-9650, 1995.
• HIROSHI HANDA. Silk gland factor-1 involved in the regulation of bombyx sericin-1 gene Contains fork head motif., J. Biol. Chem, Vol. 279, pp. 934-9346, 1995.
• HIROSHI HANDA. Replication factor encoded by a putative oncogene, set, associated with myeloid leukemogenesis., Proc. Natl. Acad. Sci. USA, Vol. 92, pp. 4279-4283, 1995.
• HIROSHI HANDA. Regional mapping of two subunits of transcription factor E4TFI to human chromosome., Jap. J. Can. Res., Vol. 86, pp. 10-12, 1995.
• HIROSHI HANDA. Regulation of influenza virus RNA polymerase activity by cellular and viral factors., Nucleic Acids Res., Vol. 22, pp. 5047-5053, 1994.
• 荒木かおる, 笹部哲生, 大橋裕一, 安田昌弘, 半田宏, 田野保雄 . SV40-Adenovirusレコンビナントベクタ－により不死化された　　 ラット角膜上皮細胞について , 日本眼科学会雑誌, Vol. 98, pp. 327-333, 1994.
• 半田宏. 1993年度ノ－ベル医学生理学賞, 日本評論社からだの科学 , Vol. 175, pp. 22, 1994.
• 半田宏. 1993年ノ－ベル生理学医学賞、”分断遺伝子”を発見したP.シャ－プとR.ロバ－ツ－ , 現代化学, Vol. 274, pp. 18-22, 1994.
• 半田宏. 1993年ノ－ベル賞受賞者の業績と人柄, 科学, Vol. 64, pp. 9-11, 1994.
• 半田宏. フィリップ･シャ－プ博士とリチャ－ド･ロバ－ツ博士の業績, 蛋白質核酸酵素, Vol. 39, pp. 83-87, 1994.
• E.Savoysky, T.Mizuno, Y.Sowa, H.Watanabe, J-I.Sawada, H.Nomura, Y.Ohsugi, H.Handa, T.Sakai . The retinoblastoma binding factor 1 (RBF-1) site in RB gene promoter binds preferentially E4TF1, a member of the Ets transcription factors family , Oncogene, Vol. 9, 1839-1846, 1994.
• J-I.Sawada, M.Goto, C.Sawa, H.Watanabe, H.Handa. Transcriptional regulation through the tetrameric complex formation of E4TF1 subunits , EMBO J, Vol. 13, pp. 1396-1402, 1994.
• Y.Sumi, T.Shiroya, K.Fujimoto, T.Wada, H.Handa, H.Kawaguchi. Application of cationic latex particles for protein separation, Colloids and Surfaces B: Biointerfaces , Vol. 2, pp. 419-427, 1994.
• 半田宏. 分断遺伝子の発見が与えた衝撃, 化学, Vol. 49, No. 2, pp. 40-45, 1994.
• 半田宏. 遺伝子発現と転写因子, メビオ, Vol. 11, No. 1, pp. 50-57, 1994.
• 半田宏. DNA固定化ラテックス粒子の診断薬への応用, バイオインダストリー, Vol. 11, No. 11, pp. 12-18, 1994.
• HIROSHI HANDA. Multiple nuclear localization signals of the B-myb gene product, FEBS Lett., Vol. 350, pp. 55-60, 1994.
• HIROSHI HANDA. Synthesis of novel optically active polymethacrylamide having L-leucine structure in the side chain, Macromolecules, Vol. 27, pp. 7928-7929, 1994.
• HIROSHI HANDA. Preparation of DNA-carrying latex and purification of transcription factors with the latex., J. Biomater. Sci. Polymer Edn., Vol. 5, pp. 293-302, 1994.
• HIROSHI HANDA. The retinoblastoma binding factor 1 (RBF-1) site in RB gene promoter binds preferentially E4TFI, a member of the Ets transcription factors family., Oncogene, Vol. 9, pp. 1839-1846, 1994.
• HIROSHI HANDA. Hemopoietic supportive function of human bone marrow stromal cell lines established by a recombinant SV40-adenovirus vector., Exp. Hematol., Vol. 22, pp. 482-487, 1994.
• 半田宏. 遺伝子発現と転写因子DNAウイルスー転写調節モデル系として-, Mebio, Vol. 11, No. 1, pp. 50-57, 1994.
• HIROSHI HANDA. cDNA cloning of transcription factor E4TFI subunits with ETS and Notch motifs., Mol. Cell. Biol., No. 13, pp. 1385-1391, 1993.
• HIROSHI HANDA. Studies of HIV-I protease inhibitors. I. Incorpration of a reduced peptide, simple aminoalcohol and statine analog at the specific site of substrate sequence, Chem. Pharm. Bull., No. 41, pp. 1369-1377, 1993.
• HIROSHI HANDA. Studies of HIV-1 protease inhibitors. II. incorporation of four types of hydroxyethylene dipeptide isosteres at the scissile site of substrate sequences., Chem. Pharm. Bull., No. 41, pp. 1378-1386, 1993.
• HIROSHI HANDA. Immnortalization of rabbit corneal epithelial cells by a recombinant SV40- adenovirus vector., Invest. Ophthalmol. Vis. Sci., No. 34, pp. 2665-2671, 1993.
• HIROSHI HANDA. Isolation of a cDNA encoding the largest subunit of TFIIA reveals functions important for activated transcription., Genes & Dev., No. 7, pp. 2246-2257, 1993.
• 半田宏. がん研究における百年史,臨床内科医会講演集　第二巻, 東京研文社, pp. 219-244, 1993.
• 半田宏, 田村隆明. 転写因子研究法, 羊土社, 1993.
• H.Tabuchi, H.Handa, S.Hirose. Underwinding of DNA on binding of yeast TFIID to the TATA element, Biochem. Biophys. Res. Commun, Vol. 192, pp. 1432-1438, 1993.
• 半田宏. アテツウイルス遺伝子の転写制御, 実験医学, Vol. 11, No. 8, pp. 98-104, 1993.
• HIROSHI HANDA. Novel 8-base pair Sequence(Drosophila DNA Replication-related Element)and Specific Binding Facter Involved in the Expressiorc of Drosophila Genes for DNA polymerase α and Proliferating Cell Nuclear Antigen, J. Biol. Chem, Vol. 268, No. 3, pp. 2092-2099, 1993.
• HIROSHI HANDA. A common trans-acting factor to the promoters of steroidogenic P-450c, J. Biol. Chem., Vol. 267, No. 28, pp. 17913-17919, 1992.
• 半田宏. ラテックス粒子を用いた転写因子の精製法, 実験医学, Vol. 10, pp. 95-99, 1992.
• HIROSHI HANDA. Application of cationic latex particles for protein separation., Colloids and Surfaces B : Biointerfaces, Vol. 2, pp. 419-427, 1992.
• 猪口貞樹, 半田宏, 島村和男, 城所正子, 中村嘉彦, 赤塚明, 上田守三, 正津晃, 橋本一男, 三富利夫 . SV40初期遺伝子導入ヒト表皮細胞の分化, 日本熱傷学会, Vol. 18, pp. 61-66, 1992.
• 今井剛, 半田宏. 腎と分子生物学, 腎と透析, Vol. 33, pp. 25-30, 1992.
• 和田忠士, 半田宏. アデノウイルスの転写制御, 生物物理, Vol. 32, pp. 16-20, 1992.
• 和田忠士, 半田宏. アデノウイルスの複製と遺伝子発現「生命科学を推進する分子ウイルス学」, 蛋白質核酸酵素, Vol. 37, pp. 2511-2518, 1992.
• 島村和男, 猪口貞樹, 半田宏, 上山義人. 培養ヒト表皮細胞のin vitroにおける分化増殖モデルの開発, Medical Immunology, Vol. 24, pp. 227-231, 1992.
• HIROSHI HANDA. Direct purification of multiple ATF/E4TF3 polypeptides from HeLa all crude nuclear extracts using DNA attinity latex particles, Anal. Biochem., pp. 206, 1992.
• Y.Hosaka, A.Kitamoto, M.Shimojo, K.Nakajima, Y.Imai, H.Handa, S.Kohsaka . Generation of microglia cell lines by transfection with simian virus 40 large T gene , Neursci. Lett, Vol. 4, pp. 139-142, 1992.
• T.Hashimoto, K-I.Morohashi, T.Takayama, S-I.Honda, T.Wada, H.Handa, T.Omura . Cooperative transcription activation between Ad1, a CREB-like element, and other elements in the CYPB gene promoter , J. Biochem, Vol. 112, pp. 573-575, 1992.
• F.Hirose, M.Yamaguchi, H.Handa, Y.Inomata, A.Matsukage. Novel 8-bp sequence (DRE) and specific binding factor (DREF) involved in the expression of Drosophila genes for DNA polymeraseαand proliferating cell nuclear antigen , J. Biol. Chem, Vol. 268, pp. 2092-2099, 1992.
• T.Hashimoto, K-I.Morohashi, T.Takayama, S-I.Honda, T.Wada, H.Handa, T.Omura . Cooperative transcription activation between Ad1, a CREB-like element, and other elements in the CYPB gene promoter , J. Biochem, Vol. 112, pp. 573-575, 1992.
• F.Hirose, M.Yamaguchi, H.Handa, Y.Inomata, A.Matsukage. Novel 8-bp sequence (DRE) and specific binding factor (DREF) involved in the expression of Drosophila genes for DNA polymeraseαand proliferating cell nuclear antigen , J. Biol. Chem, Vol. 268, pp. 2092-2099, 1992.
• M.Sakurai, M.Sugano, S.Higashida, A.Kasuya, S.Miyamoto, H.Handa, T.Komai, R.Yagi, T.Nishigaki, Y.Yabe . Synthesis of HIV-1 protease inhibitors. In Peptide Chemistry 1992. (ed. N.Yanaihara) , ESCOM, pp. 532-534, 1992.
• K.Sogawa, H.Handa, A.Fujisawa-Sehara, T.Hiromasa, M.Yamane, Y.Fujii-Kuriyama . Repression of cytochrome P450c gene expression by cotransfection with adenovirus E1a DNA. In Molecular Biology of chytichrome P-450 (ed. T.Omura) , Kyushu University Press, pp. 97-102, 1992.
• 半田宏. DNAアフィニティ－粒子による転写因子の精製, 生化学, Vol. 64, pp. 404-407, 1992.
• HIROSHI HANDA. Transcriptical regulation by a point mutant of adnovirus-2 E1a product lacking DNA binding activity, J. Biol. Chem., No. 267, pp. 20181-20187, 1992.
• 半田宏. アデノウイルス感染症, Medical Immunology, Vol. 21, 366-374, 1991.
• T.Imai, H.Kawaguchi, T.Wada, H.Handa. E1A gene products stimulate in vitro transciption from the adenovirus early region 4 promoter by enhancing stable preinitiation complex , Virus Genes, Vol. 5, pp. 47-55, 1991.
• S.Aizawa, N.Yaguchi, M.Nakano, S.Inokuchi, H.Handa, K.Toyama. Establishment of a variety bone marrow stromal cell lines by the recombinant SV40-adenovirus vector , J. Cell. Physiol, Vol. 148, pp. 245-251, 1991.
• M.S.Sato, C.Moriyama, A.Asai, H.Handa, M.F.Rajewsky, T.Kuroki, M.Huh. Monoclonal antibody-mediated solid-phase assay of mammalian O6-alkylguanine DNA alkyltransferase activity , Anal. Biochem, Vol. 196, pp. 245-251, 1991.
• T.Hibi, T.Fujisawa, T.Kanai, A.Akatsuka, S.Habu, H.Handa, M.Tsuchiya. Establishment of epithelial cell lines from human and mouse thymus immortalized by the 12S adenovirus E1A gene product , Thymus, Vol. 18, pp. 155-167, 1991.
• S.Inokuchi, M.Ueda, K.Hashimoto, H.Handa, T.Mitomi. Immortalization of human epidermal keratinocytes by the recombinant SV40-adenovirus vector , In Vitro Cell. Dev. Biol, Vol. 27, pp. 827-828, 1991.
• S.Inokuchi, M.Ueda, K.Hashimoto, H.Handa, T.Mitomi. Calcium induced differentiation of SV40 immortalized human epidermal keratinocytes cultured in defined medium , Tokai J. Exp. Clin. Med, Vol. 16, pp. 223-229, 1991.
• H.Kawaguchi, A.Asai, Y.Ohtsuka, H.Watanabe, T.Wada, H.Handa. Purification of DNA-binding transcription factors by their selective adsorption on the affinity latex particles. In Transcription Regulation Mechanisms in Eukaryotic Genes. (ed. M.Muramatsu) , Nakanishi Printing Co., Ltd, pp. 18-36, 1991.
• HIROSHI HANDA. Different biological activities of the hetero-and homodimers formed by the 47Kd and 43Kd proteins of transcription factor ATF/E4TF3., J. Vitol, pp. 65, 1991.
• HIROSHI HANDA. Negative supercoiling of DNA facilitates on interaction between tromscription factor IID and fibroin gene promoter, Proc. Natl. Acad. Sci USA, pp. 88, 1991.
• HIROSHI HANDA. Affinity-purification of transcription factor IIA from HeLa cell nuclear extracts., EMBO J., pp. 10, 1991.
• 半田宏. ガン研究の100年史, 健康管理,保健文化社, Vol. 11, pp. 1-26, 1991.
• 猪股幸雄, 川口春馬, 和田忠士, 半田宏. 転写制御タンパク分離精製用のDNAアフィニティ－ラテックスの改良, 高分子論文集,高分子学会, Vol. 48, pp. 335-340, 1991.
• 和田忠士, 半田宏, 猪股幸雄, 川口春馬. DNAアフィニティ－クロマトグラフィ－･ラテックス粒子による転写因子の精製 , Cell Science, Vol. 7, pp. 373-381, 1991.
• 半田宏. バイオテクノロジ－の最前線, 東京工業大学研究･情報交流センタ－（平成3年度東京工業大学公開講座）, pp. 23-32, 1991.
• 半田宏. 細胞増殖と核タンパク質のリン酸化, オンコロジア, Vol. 23, pp. 145-146, 1990.
• T.Wada, Y.Nogi, H.Handa, T.Fukasawa. Strain-specific lethal effect of adenovirus E1a protein of Saccharomyces cerevisiae , Biochem. Biophys. Res.Commun , Vol. 170, pp. 470-476, 1990.
• 半田宏. 医学における遺伝子工学のトピックス, 中央区医師会雑誌, Vol. 5, pp. 20-30, 1990.
• 渡辺肇, 和田忠士, 臼田佳弘, 半田宏. 転写調節におけるタンパク質因子間相互作用, 蛋白質核酸酵素, Vol. 35, pp. 2825-2831, 1990.
• H.Watanabe, T.Wada, H.Handa. Transcription factor E4TF1 contains two subunits with different functions , EMBO J, Vol. 9, pp. 841-847, 1990.
• H.Handa, H.Watanabe, Y.Suzuki, S.Hirose. Effect of DNA supercoiling on transcription from the adenovirus early region 4 , FEBS Lett, Vol. 249, pp. 17-20, 1989.
• K.Sogawa, H.Handa, A.Fujisawa-Sehara, T.Hiromasa, M.Yamane, Y.Fujii-Kuriyama . Repression of cytochrome P-450c gene expression by the adenovirus E1A gene products , Eur. J. Biochem, Vol. 181, pp. 539-544, 1989.
• HIROSHI HANDA. Purification of DNA-binding transcription factors by their selective adsorption on the affinity latex panticles, Nucleic Acids Res., pp. 17, 1989.
• 半田宏. アデノウイルス初期遺伝子の転写制御, 実験医学, Vol. 7, pp. 77-83, 1989.
• HIROSHI HANDA. Transcription in the reverse orientation at either terminus of the adenovirus type 5 genome., EMBO J., pp. 8, 1989.
• T.Nishigaki, S.Hanaka, R.E.Kingston, H.Handa. A specific domain of the adenovirus EIV promoter is necessary to maintain susceptibility of the integrated promoter to E1A transactivation , Mol. Cell Biol, Vol. 8, pp. 353-360, 1988.
• T.Kohama, H.Handa, K.Harigaya. A burst-promoting activity derived from the human bone marrow stromal cell line KM102 is identical to the granulocyte-macrophage colony-stimulating factor , Exp. Hematol, Vol. 16, pp. 603-608, 1988.
• A.Abe, T.Wada, H.Handa, Y.Nogi, T.Fukasawa. Efficient usage of galactose-inducible expression vector in production of heterologus protein in yeast , Agric.Biol.Chem , Vol. 52, pp. 2035-2041, 1988.
• Y.Akahori, H.Handa, K.Imai, M.Abe, K.Kameyama, M.Hibiya, H.Yasui, K.Okamura, M.Naito, H.Matsuoka, Y.Kurosawa . Sigma region located between Cμand Cδ genes of human immunoglobulin heavy chain: Possible involvement of tRNA-like structure in RNA splicing , Nucleic Acids Res, Vol. 16, pp. 9497-9511, 1988.
• HIROSHI HANDA. Identification of two transcription factors that bind to specific elements in the promoter of the adonovirus early region 4., Mol. Cell. Biol., pp. 8, 1988.
• 渡辺肇, 半田宏. 熱ショックタンパク質, 細胞工学, Vol. 7, pp. 27-33, 1988.
• 半田宏, 村松正美. 遺伝子工学, 丸善株式会社, 1988.
• 半田宏. 微生物実習提要, 東京大学医科学研究所学友会編,丸善株式会社, 1988.
• 半田宏. アデノウイルス転写の機構, ウイルス, Vol. 37, pp. 229-240, 1987.
• S.Hanaka, T.Nishigaki, P.A.Sharp, H.Handa. Regulation of in vitro and in vivo transcription of early region IV of adenovirus type 5 by multiple cis-acting elements , Mol. Cell. Biol, Vol. 7, pp. 2578-2587, 1987.
• 半田宏. パルボウイルス･ベクタ－, ウイルス,日本ウイルス学会, Vol. 37, pp. 23-31, 1987.
• 渡辺肇, 半田宏. 熱ショックタンパク質と癌遺伝子, オンコロジア,オンコロジア社, Vol. 16, pp. 125-127, 1986.
• 半田宏. 特異塩基配列を用いた転写制御因子の分離･精製, 学術月報, Vol. 39, pp. 39, 1986.
• K.Oda, M.Masuda-Murata, K.Shiroki, H.Handa. Mitogenic activity of the adenovirus type 12 E1A gene induced by hormones in rat cells , J. Virol., Vol. 58, pp. 125-133, 1986.
• 半田宏, 渡辺肇, 西垣隆. アデノウイルスE4遺伝子の転写制御, 蛋白質核酸酵素, Vol. 30, pp. 1570-1579, 1985.
• H.Handa, K.Mizumoto, K.Oda, H.Okamoto, T.Fukasawa. Transcription of the human adenovirus E1A gene in Saccharimyces cerevisiae , Gene, Vol. 33, pp. 159-168, 1985.
• K.Harigaya, H.Handa. Generation of functional clonal cell lines from human bone marrow stroma , Proc. Natl. Acad. Sci. USA, Vol. 82, pp. 3477-3480, 1985.
• 半田宏. ウイルス遺伝子による発癌機構, 日本医師会雑誌,日本医学会, Vol. 92, pp. 6005-6111, 1984.
• 半田宏. ウイルスベクタ－の利用, 蛋白質核酸酵素, Vol. 27, pp. 389-394, 1984.
• H.Handa, P.A.Sharp. Requirement for distal upstream sequences for maximal transcription in vitro of early region IV of adenovirus , Mol. Cell. Biol, Vol. 4, pp. 791-798, 1984.
• 半田宏. 動物細胞の発現調節, 細胞工学, Vol. 3, pp. 970-977, 1984.
• 半田宏. 癌細胞に発現する細胞周期に関与するp53遺伝子, 細胞工学,秀潤社, Vol. 3, pp. 780-787, 1984.
• M.Notake, T.Kurosaki, T.Yamamoto, H.Handa, M.Mishina, S.Numa. Sequence requirement for in vitro transcription of the human corticotropin/β-Lipotropin precursor gene , Eur. J. Biochem, Vol. 133, pp. 599-605, 1983.
• HIROSHI HANDA. Inhibition of adenovirus early region IV transcription in vitro by purified viral 72,000 DNA binding protein, Nature, No. 302, pp. 545-547, 1983.
• 半田宏. アデノウイルス遺伝子のin vitro転写系, 蛋白質核酸酵素、共立出版株式会社, Vol. 27, pp. 2457-2465, 1982.
• 半田宏. SV40遺伝子の転写, 生化学、日本生化学学会, Vol. 54, pp. 95-98, 1982.
• 内田清二郎, 余郷嘉明, 菅野純夫, 半田宏, 吉池邦人, 小田欽一郎, 羽倉明 . パポバウイルスの最近の知見, 代謝、中山書店, Vol. 19, pp. 75-87, 1982.
• 半田宏. 逆転写酵素の発見, 循環、メジカルビュー社, Vol. 12, pp. 23-24, 1981.
• I.Saito, J.Sato, H.Handa, K.Shiroki, H.Shimojo. Mapping of RNAs transcribed from adenovirus type 12 early VA RNA regions , Virology, Vol. 114, pp. 379-398, 1981.
• 半田宏. ウイルス遺伝の転写－主にmRNAのプロセッシング－, 医学の歩み、医歯薬出版株式会社, Vol. 117, pp. 409-419, 1981.
• H.Handa, R.J.Kaufman, J.L.Manley, M.L.Gefter, P.A.Sharp. Transcription of SV40 DNA using mammalian cell extracts , J. Biol. Chem, Vol. 256, pp. 478-482, 1981.
• C.L.Cepko, U.Hansen, H.Handa, P.A.Sharp. Sequential transcription-translation of SV40 using mammalian cell extracts , Mol. Cell. Biol, Vol. 1, pp. 919-931, 1981.
• H.Handa, P.A.Sharp. Expression of early and late SV40 transcripts in the absence of protein synthesis, J. Virol, Vol. 34, pp. 592-597, 1980.
• J.L.Manley, H.Handa, S-Y.Huang, M.L.Gefter, P.A.Sharp. Transcription of animal virus genes in vitro. In Mobilization and Reassembly of Genetic Information. (eds. W.A.Acott et al) , Academic Press, Inc, pp. 361-378, 1980.
• H.Handa, B.J.Carter. Adeno-associated virus DNA replication complexes in herpes simplex virus or adenovirus-infected cells, J. Biol. Chem, Vol. 254, pp. 6603-6610, 1979.
• K.Hashimoto, H.Handa, K.Umehara, S.Sasaki. Germfree mice reared on an antigen-free diet, Lab. Animal Science, Vol. 28, pp. 38-45, 1978.
• H.Handa, T.Toda, M.Tajima, T.Wada, H.Iida, T.Fukasawa. Expression of the human adenovirus E1A product in yeast , Gene, Vol. 58, pp. 127-136, 1978.
• H.Handa, K.Shiroki, H.Shimojo. Isolation and characterization of KB cell lines latently infected with adeno-associated virus type 1. In Parvovirus: Replication and Biological Properties. (eds. D.C.Ward and P.Tattersall), Cold Spring Harbor, New York, pp. 77-86, 1978.
• H.Handa, K.Shiroki, H.Shimojo. In Parvovirus: Replication and Biological Propeties. (eds. D.C.Ward and P.Tattersall), Cold Spring Harbor, New York, pp. 99-108, 1978.
• K.Shiroki, H.Handa, H.Shimojo, S.Yano, S.Ojima, K.Fujinaga. Establishment and characterization of rat cell lines transformed by restriction endonuclease fragment of adenovirus 12 DNA, Virology, Vol. 82, pp. 462-471, 1977.
• H.Handa, K.Shiroki, H.Shimojo. A helper function(s) for growth of adeno-associated virus in cells transformed by adenovirus 12, Proc.Natl.Acad.Sci.USA, Vol. 74, pp. 4508-4510, 1977.
• H.Handa, K.Shiroki, H.Shimojo. Establishment and characterization of KB cell lines latently infected with adeno-associated virus type 1, Virology, Vol. 82, pp. 84-92, 1977.
• H.Handa, H.shimojo. Viral DNA sysnthesisin vitro with nuclei isolated from adeno-associated virus type 1-infected cells, Virology, Vol. 77, pp. 424-428, 1977.
• H.Handa, H.Shimojo. Isolation of the viral DNA replication complex from adeno-associated virus type 1-infected cells, J.Virol, Vol. 24, pp. 444-450, 1977.
• 半田宏. Adeno-Association Virus １型(AAV1)の増殖の解析, 慶応医学, Vol. 53, pp. 469-478, 1976.
• H.Handa, H.Shimojo, H.Yamagushi. Multiplication of adeno-associated virus type 1 in cells coinfected with a temperature-sensitive mutant of human adeno-virus type 31, Virology, Vol. 74, pp. 1-15, 1976.
• H.Handa, K.Shiroki, H.Shimojo. Complementation of adeno-associated virus growth with temperature-sensitive mutants of human adenovirus types 12 and 5., J.Gen.Virol, Vol. 29, pp. 239-242, 1975.

著書

• 半田宏, 山口雄輝. 新しい遺伝子工学 新版, 朝倉書店, Sept. 2014.
• 坂本聡, 半田宏. 技術予測レポート2023 上巻 「健康寿命の延伸を目指す」日本の技術編, 日本能率協会総合研究所, ソレカラ社, Dec. 2013.
• 半田宏, 加部泰明, 末松誠. 見つける、量る、可視化する! 質量分析実験ガイド〜ライフサイエンス・医学研究で役立つ機器選択、サンプル調製、分析プロトコールのポイント, 実験医学別冊 最強のステップUPシリーズ, 羊土社, pp. 58-68, Apr. 2013.
• 西尾広介, 坂本聡, 宇賀均, 倉森見典, 半田宏. 磁性ビーズのバイオ・環境技術への応用展開（普及版）, CMCテクニカルライブラリー―新材料・新素材シリーズ, シーエムシー出版, pp. 144-153, June 2012.
• 壷内信吾, 池田森人, 成松宏樹, 半田宏. ソフトナノテクノロジーにおける材料開発（普及版）, CMCテクニカルライブラリー―新材料・新素材シリーズ, シーエムシー出版, Dec. 2011.
• 畠山士, 半田宏. ナノ融合による先進バイオデバイス, バイオテクノロジーシリーズ, シーエムシー出版, pp. 8-17, Dec. 2011.
• 畠山士, 加部泰明, 半田宏. ナノ粒子分散系の基礎と応用, CMCテクニカルライブラリー―ファインケミカルシリーズ, シーエムシー出版, Nov. 2011.
• Masaaki Kawano, Li Xing, Kit S. Lam, Hiroshi Handa, Tatsuo Miyamura, Susan Barnett, Indresh K. Srivastava, R. Holland Cheng. Development of Vaccines: From Discovery to Clinical Testing, Wiley, pp. 125-140, Aug. 2011.
• 西尾広介, 池田森人, 成松宏樹, 壺内信吾, 郷右近展之, 半田宏. 医療分野における材料と機能膜（普及版）, CMCテクニカルライブラリー―新材料・新素材シリーズ, シーエムシー出版, pp. 204-214, June 2011.
• Masanori Abe, Hiroshi Handa. Biocompatible Nanomaterials: Synthesis, Characterization and Applications, Nanotechnology Science and Technology, Nova Science Pub Inc, pp. 225-241, July 2010.
• 半田宏, 畠山士. コアシェル微粒子の設計・合成技術・応用の展開, シーエムシー出版, p. 204-214, July 2010.
• 壺内信吾, 西尾広介, 池田森人, 成松宏樹, 郷右近展之, 半田宏. ナノ粒子・マイクロ粒子の調製と応用技術（普及版）, CMCテクニカルライブラリー―ファインケミカルシリーズ, シーエムシー出版, pp. 219-228, Apr. 2010.
• 半田宏, 伊藤武彦, 岩崎博史, 岡田典弘, 岸本健雄, 工藤明, 白髭克彦, 田中幹子, 徳永万喜洋, 広瀬茂久, 村上聡, 菊池韶彦. ハートウェル遺伝学-遺伝子、ゲノム、そして生命システムへ-, メディカルサイエンスインターナショナル, Mar. 2010.
• Yasuaki Kabe, Mamoru Hatakeyama, Satoshi Sakamoto, KOSUKE NISHIO, Hiroshi Handa. Novel Applications of Affinity Beads, PROTEIN TARGETING WITH SMALL MOLECULES, Chemical Biology Techniques and Applications, Jhon Wiley & Sons. Inc., 2009.
• 半田宏, 和田忠士, 坂本聡. 診断学、１．ＭＥＭＳと診断 他, ＭＥＭＳ／ＮＥＭＳ工学全集, 株式会社テクノシステム, p. 212-217, 2009.
• 山口雄輝, 半田宏. 転写制御とエピジェネティクス—ゲノムデコードに向けて, 南山堂, Dec. 2008.
• Sophie Delehouzee, 山口雄輝, 半田宏. ヒトの分子生物学, 丸善株式会社, pp. 618-635, 2006.
• 中村栄一, 濱口宏夫, 半田宏. 化学の明日を考える, 化学, Vol. 1, pp. 12-17, 2006.
• 加部泰明, 坂本聡, 半田宏. タンパク質を操るビーズ技術, バイオニクス, Vol. 10, pp. 32-38, 2006.
• 半田　宏. 東京工業大学21世紀COEプログラム　生命工学フロンティアシステム, 化学と工業, Vol. ６, pp. 4-8, 2006.
• 半田宏, 阿部正紀. 機能性磁性ビーズの構築とバイオテクノロジーへの応用（2）, ライフサイエンスニュースレター　日本語版, No. 4, pp. 31-33, 2006.
• 半田宏, 和田忠士, 山口雄輝. 転写研究集中マスター, 羊土社, pp. 12-26, 2006.
• 半田宏. ナノ粒子分散系の化学と技術, シーエムシー出版, pp. 295-307, 2006.
• 半田宏. 新しい遺伝子工学, 昭晃堂, 2006.
• 半田宏, 阿部正紀, 野田紘憙. 磁性ビーズのバイオ・環境技術への応用展開, シーエムシー出版, 2006.
• 野村祥太郎, 望月勇輔, 西尾広介, 坂本聡, 半田宏. ナノ磁性微粒子による遺伝子導入法, 遺伝子医学MOOK, No. 5, 2006.
• 半田宏, 阿部正紀. 機能性磁性ビーズの構築とバイオテクノロジーへの応用（１）, ライフサイエンスニュースレター 日本語版第3号, pp. 29-31, 2005.
• 川野雅章, 金刺進之介, 高橋陵宇, 井上隆昌, 半田宏. ＤＤＳ研究の現状と将来展望, PHARM TECH JAPAN, Vol. 12, pp. 168-171, 2005.
• 半田宏　共訳. バイオテク用語辞典, 東京化学同人, 2005.
• 郷右近展之, 半田宏. 機能性ナノ磁気ビ－ズの構築とバイオテクノロジ－への応用, 未来材料, Vol. 5, pp. 44-46, 2005.
• 壷内信吾, 池田森人, 成松宏樹, 半田宏. ソフトナノテクノロジー‐バイオマテリアル革命‐, シ－エムシ－出版, 2005.
• 加部泰明, 平尾聡, 半田宏. ナノテクノロジ－の医学への応用-アフィニティナノ粒子を用いた医薬開発の応用展開-, 炎症と免疫, Vol. 2, pp. 3-10, 2005.
• 半田宏　共著. 医療機器と再生医療―開発最前線と今後の動向―, 情報機構, 2005.
• 半田　宏, 阿部正紀, 郷右近展之, 西尾広介. バイオ・医療を志向する次世代の磁性微粒子, シーエムシー出版, シーエムシー出版, No. 8月, pp. 5-6,7-13,21-30, 2004.
• 川口春馬, 杉本忠夫, 山本孝夫, 岩村武, 中條善樹, 福井寛, 菊地隆司, 星川豊久, 江口浩一, 藤正督, 澤上一美, 田島秀二, 今岡享稔, 山元公寿, 鳥越幹二郎, 江角邦男, 長井勝利, 半田宏. ナノ粒子・マイクロ粒子の最先端技術, シーエムシー出版, シーエムシー出版, 2004.
• 宮崎榮三, 猪飼篤, 岩本光正, 髙柳邦夫, 福井賢一, 和田昭英, 枝元一之, 鯉沼秀臣, 間中孝彰, 梶川浩太郎, 池田富樹, 渡辺順次, 竹添秀男, 半那純一, 半田宏, 跡部真人, 大坂武男, 半田宏. 表面科学の基礎と応用, エヌ・ティー・エス, エヌ・ティー・エス, 2004.
• 半田宏　共訳. 「ゲノム 2」村松正實　監訳, メディカル・サイエンス・インターナショナル, メディカル・サイエンス・インターナショナル, 2003.
• 半田宏. アフィニティナノビーズの構築と創薬への応用　Bioベンチャー, 羊土社, 羊土社, Vol. 3, pp. 90-92, 2003.
• 半田宏　川口春馬. ナノアフィニティビーズのすべて, 中山書店, 中山書店, 2003.
• 長谷川慎, 半田宏. ポストゲノムシークエンス時代の細胞内タンパク質複合体ネットワークの解析、化学, （株）化学同人, （株）化学同人, Vol. 57, No. 12, 2002.
• 半田宏　共著：小泉光惠, 奥山喜久夫, 目　義雄　編集. ナノ粒子の製造・評価・応用・機器の最新技術, Recent Advamces in Nano Power Technology-Preparation,Evaluation,Utilization and Equipments-　（株）シーエムシー出版, Recent Advamces in Nano Power Technology-Preparation,Evaluation,Utilization and Equipments-　（株）シーエムシー出版, 2002.
• 半田　宏　編集, 山口雄輝　共著. 転写がわかる　-基本転写から発生、再生、先端医療まで-, 羊土社, 羊土社, 2002.
• 半田　宏　共著, 柳田　博明　監修. 微粒子工学大系　第ニ巻　応用技術, フジ・テクノシステム, フジ・テクノシステム, 2002.
• 半田　宏. サイエンスは個性＆プライド, MEDCHEM NEWS　、社）日本薬学会, MEDCHEM NEWS　、社）日本薬学会, Vol. 12, pp. 6-9, 2002.
• 半田宏. 「NAVIGATOR -Vascular Biologyﾅﾋﾞｹﾞｰﾀｰ‐」, メディカルレビュー社, メディカルレビュー社, 2001.
• 半田宏, 古谷利夫, 増保安彦, 辻本豪三. 「ゲノム創薬－創薬のパラダイム－」, 中山書店, 中山書店, 2001.
• 半田宏　共著. ｢基礎生化学実験法　第3巻 タンパク質Ⅱ 機能・動態解析法｣日本生化学会編, 東京化学同人, 東京化学同人, 2001.
• 半田宏　共著. 「転写因子と疾患」村松正實　編集, 医歯薬出版株式会社, 医歯薬出版株式会社, 2001.
• 石井俊輔, 加藤茂明, 半田宏, 藤井義明, 山本雅之. 転写因子の機能, 蛋白質核酸酵素　増刊, 蛋白質核酸酵素　増刊, Vol. 45, No. 9, pp. 1473－1475,1476－1483, 2000.
• 半田宏, 川口春馬, 松本史朗他. 微粒子・粉体の最先端技術, 株式会社シーエムシー, 株式会社シーエムシー, 2000.
• 半田宏, 石井俊輔, 山本雅之, 藤井義明. ゲノムからの情報発現, シュプリンガー・フェアラーク東京株式会社, シュプリンガー・フェアラーク東京株式会社, 2000.
• HIROSHI HANDA. Real-Time Analysis of Biomolecular Interactions:Applications of BIACORE, Springer, Springer, 2000.
• H.Handa, Y.Yamaguchi& T.Wada. Purification of DNA binding proteins High Resolution Chromatography: A Practical Approach, Oxford University Press, Oxford University Press, pp. 283-302, 1999.
• T.Wada, T.Takagi, Y.Yamaguchi, K.Kawase, M.Hiraomoto, A.Ferdous, M.Takayama, K.A.W.Lee, H.C.Hurst, H.Handa. Copurification of casein kinase II with transcription factor ATF/E4TF3, Alternation of Transcription by DNA Tumor Virus Proteins, Alternation of Transcription by DNA Tumor Virus Proteins, pp. 27-35, 1999.
• 半田宏. 細胞機能と代謝マップ　II.　細胞の動的機能, 東京化学同人, 東京化学同人, 1999.
• 半田宏. 環境ホルモン汚染対策－測定･評価から企業対策まで－, 株式会社　エヌ･ティ－･エス, 株式会社　エヌ･ティ－･エス, 1999.
• 半田宏共著. 新遺伝子工学ハンドブック, 羊土社, 羊土社, 1999.
• 半田宏. Bio Science新用語ライブラリ－、転写因子、第2版, 羊土社, 羊土社, 1999.
• 半田　宏. 転写因子研究1999－基本転写因子・フロマチニ制御から医学研究まで－；(), 羊土社, 羊土社, 1999.
• 半田宏. 「生化学辞典」第3版, 東京化学同人, 東京化学同人, 1998.
• 日本化学学会　編, 半田宏. 「細胞機能と代謝マップII. 細胞の動的機能」, 東京化学同人, 東京化学同人, 1998.
• 永田和宏, 半田宏　共編. 「生体物質相互作用のリアルタイム解析実験法」, シュプリンガ－･フェアラ－ク東京, シュプリンガ－･フェアラ－ク東京, 1998.
• 半田宏. 転写因子研究の最前線'97, 羊士社, 羊士社, 1997.
• 半田宏. 遺伝子診療, 医学書院, 医学書院, 1997.
• 半田宏. わかりやすい遺伝子工学, 昭晃堂, 昭晃堂, 1997.
• HIROSHI HANDA. Affinity latex for DNA diagnosis, Advances in Polymer Biomaterials, Advances in Polymer Biomaterials, 1997.
• 半田宏. 新遺伝子工学ハンドブック, 羊士社, 羊士社, 1996.
• 半田宏. 転写因子,生物機能調節の要, 共立出版株式会社, 共立出版株式会社, 1996.
• 半田宏. 転写のしくみと疾患, 羊士社, 羊士社, 1996.
• 半田宏. Bio Science用語ライブラリー,転写因子, 羊士社, 羊士社, 1995.
• HIROSHI HANDA. DNA affinity chromatography, Methods in Enzymology, Methods in Enzymology, 1995.
• HIROSHI HANDA. Preparation of DNA-carrying affinity latex and purification of transcription factor with the latex., Polymer Biomaterials in Solution, as interfaces and as Solids., Polymer Biomaterials in Solution, as interfaces and as Solids., 1995.
• 半田宏. 分子生物学プロトコール, 南江堂, 南江堂, 1994.
• 半田宏. ウイルス感染症の臨床と病理, 医学書院, 医学書院, 1991.
• 半田宏. 遺伝子の発現と制御II, 丸善株式会社, 丸善株式会社, 1990.

国際会議発表 (査読なし・不明)

• Satoshi Sakamoto, Takumi Ito, Yuki Yamaguchi, Hideki Ando, Hiroshi Handa. Biochemical analyses of CRBN, the target protein for immunomodulatory drugs (IMiDs), PACIFCHEM2015, Dec. 2015.
• Satoshi Sakamoto, Yuki Yamaguchi, Takumi Ito, Hiroshi Handa. Elucidation of the molecular mechanisms of action of bioactive natural products using high performance affinity beads, PACIFCHEM2015, Dec. 2015.
• NOBUHIRO MATSUSHITA, Kazunori Nakagawa, Takaaki Taniguchi, HIROSHI HANDA, Masaru TADA, masanori abe, MASAHIRO YOSHIMURA. Polymer Coated Magnetic Beads for Bio-screening Containing Ferrite Nanoparticles Synthesized by Hydrothermal Treatment, The 10th International Conference on Ferrite, The 10th Intl. Conf. on Ferrites (Chengdu, China), Oct. 2008.
• Toshiyuki Tanaka, Masaru Tada, Takashi Nakagawa, Masanori Abe, Adarsh Sandhu, Hiroshi Handa. "Flow Tubular Reactor Method" for Synthesis of Spherical, SMA International Conference 2008 & 5th International Symposium on Nanomanufacturing, SMA International Conference 2008 & 5th International Symposium on Nanomanufacturing, 63, Jan. 2008.
• T. Kanemaru, T. Hara, M. Tada, T. Nakagawa, H. Handa, M. Abe. Ferrite hollow spheres, 200 nm in diameter, having continuous shell prepared by ferrite plating at low temperature for biomedical carrier application, 52nd Magnetism and Magnetic Materials Conference, 52nd Magnetism and Magnetic Materials Conference, Nov. 2007.
• Kazunori NAKAGAWA, Takaaki TANIGUCHI, Nobuhiro MATSUSHITA, Hiroshi HANDA, Masanori ABE, Masahiro YOSHIMURA. Hundred-nanometer Sized Bio-Magnetic Beads with Large Magnetization Using Ferrite Nanoparticles Grown by Hydrothermal Process, MMM 2007, MMM 2007 Abstracts, Nov. 2007.
• Kazunori NAKAGAWA, Takaaki TANIGUCHI, Nobuhiro MATSUSHITA, Hiroshi HANDA, Masanori ABE, Masahiro YOSHIMURA. Biomagnetic Beads Using Fe3O4 Nanparticles Grown by Hydrothermal Process, IUMRS-ICMAT 2007, IUMRS-ICMAT 2007 Abstracts, July 2007.
• T. Tanaka*, R. Shimazu, M. Tada, T. Nakagawa, A. Sandhu, H. Handa, M. Abe. Size control (50-150 nm) of spherical monodisperse ferrite nanoparticles for biomedical applications, The 1st International Symposium on Advanced Magnetic Materials and Applications, ISAMMA2007, 92, May 2007.
• K. Okawa, T. Kanemaru, M. Tada, T. Nakagawa, Y. Hase, S Nomura, M. Ikeda, K. Nishio, H. Handa, M. Abe. Heating ability of iron oxide nanoparticles at 120-900 kHz for magnetic anticancer hyperthermia, The 1st International Symposium on Advanced Magnetic Materials and Applications, ISAMMA2007, 9, May 2007.
• Abe, M., Matsushita, N., Tada, M., Gokon, N., Nishio, K., Handa, H.. Novel Medical Ferrite Nanobeads with Bioactive Molecules Immobilized Strongly onto the Surfaces, Mater. Res. Soc. Symp., pp. 1-12, 2005.

国内会議発表 (査読なし・不明)

• 坂本 聡, Gupta Vipul, 劉 舒捷, 安藤秀樹, 舘野峻平, 金子裕生, 湯上真人, 石井亮平, 濡木 理, 山口雄輝, 半田 宏. 抗炎症薬サリチル酸が示す生体内作用メカニズムの解析, 日本化学会年第97春季年会, Mar. 2017.
• 坂本 聡, 山口 雄輝, 半田宏. ターゲット因子の解析を基盤とする生物活性物質が示す作用機構の解明, 新学術領域研究「転写サイクル」冬の若手ワークショップ2017, Jan. 2017.
• 坂本 聡, 伊藤 拓水, 森 智行, 安藤 秀樹, 山口 雄輝, 箱嶋 敏雄, 半田 宏. CRBNに対するサリドマイド光学異性体の結合基盤解析, 日本ケミカルバイオロジー学会第11回年会, June 2016.
• 伊藤 拓水, 朝妻 知子, 山本 淳一, 安藤 秀樹, 佐藤 智美, 山口 雄輝, 半田 宏. リガンド依存的ユビキチンリガーゼＣＲＢＮの制御機構, 日本ケミカルバイオロジー学会第11回年会, June 2016.
• 坂本 聡, 伊藤 拓水, 安藤 秀樹, 山口 雄輝, 半田 宏. IMiDs標的タンパク質CRBNの生化学的解析, 日本ケミカルバイオロジー学会第１０回年会, June 2015.
• 坂本 聡, 山口雄輝, 半田 宏. アフィニティビーズを利用した生物活性物質標的タンパク質の単離・同定・評価, 日本薬学会第135年会, Mar. 2015.
• 曹 青福, 陳 業熹, 半田 宏, 山口 雄輝. 新規転写伸長因子ヒトRtf1が関与する転写制御の分子機構, 新学術領域研究「転写サイクル」班会議2014, Aug. 2014.
• 山口雄輝, 山本淳一, 半田宏. ヒトRNA ポリメラーゼII 転写産物のプロセシング経路の選択機構, 新学術領域研究「転写サイクル」班会議2014, Aug. 2014.
• 坂本 聡, Vipul Gupta, 劉 舒捷, 安藤 秀樹, 舘野 峻平, 金子 裕生, 湯上 真人, 石井 亮平, 濡木 理, 山口 雄輝, 半田 宏. 抗炎症薬サリチル酸の生体内作用機構の解析, 日本ケミカルバイオロジー学会第９回年会, June 2014.
• 坂本 聡, 唐澤 慧記, 東 基記, 笠間 健嗣, 宮澤 啓介, 山口 雄輝, 半田 宏. ビタミンK2が引き起こすがん細胞のアポトーシス誘導機構の解析, 日本化学会第９４春季年会, Mar. 2014.
• 曹 青福, 陳 業熹, 半田 宏, 山口 雄輝. 転写伸長因子ヒトPaf1複合体が関与する転写制御の分子機構, 新学術領域研究「転写サイクル」冬の若手ワークショップ2014, Jan. 2014.
• 柴田 紘孝, 半田 宏, 山口 雄輝. 転写伸長因子DSIFおよびNELFがES細胞の多分化能維持に果たす役割, 新学術領域研究「転写サイクル」冬の若手ワークショップ2014, Jan. 2014.
• 舩造 正英, 伊藤 拓水, 安藤 秀樹, 山口 雄輝, 半田 宏. 多発性骨髄腫におけるCRBN 結合因子の探索及び解析, 第３６回日本分子生物学会年会, Dec. 2013.
• 飯田 結, 伊藤 拓水, 安藤 秀樹, 山口 雄輝, 半田 宏. サリドマイドターゲット分子CRBN の生化学的解析, 第３６回日本分子生物学会年会, Dec. 2013.
• 阿部正紀, 中川貴, 多田大, SANDHUAdarsh, 半田宏. 医用磁性ナノビーズの作製と診断・治療への応用, 臨床病理, Vol. 55, pp. 114, Nov. 2007.
• 中川貴, 田中俊行, 島津隆一, 志村拓真, 金丸俊, 黒田カルロス清一, 多田大, 半田宏, 阿部正紀. バイオメディカル応用を目指したFeスピネルナノビーズの作製, 日本セラミックス協会第２０回秋季シンポジウム講演予稿集, 45, Sept. 2007.
• 金丸俊, 原洸, 多田大, 中川貴, 半田宏, 阿部正紀. フェライトめっき反応を用いたフェライト中空ナノ粒子の低温（６０℃）作製, 第31回日本応用磁気学会学術講演会, 第31回日本応用磁気学会学術講演会講演概要集, 120, Sept. 2007.
• 舟橋久景, 田中靖紘, 今村 佳正, 三重正和, 真鍋 孝司, 田中浩士, 高橋孝志, 相澤益男, 半田宏, 小畠英理. 電気化学ホモジニアスアッセイによるドラッグスクリーニング法の開発, 電気化学会第71回大会, 3C09, Mar. 2004.

その他の論文・著書など

• 中村栄一, 濱口宏夫, 半田宏. 「化学の明日を考える」, 化学, Vol. 1, pp. 12-17, 2006.
• 半田宏, 阿部正紀. 「機能性磁性ビーズの構築とバイオテクノロジーへの応用（2）」, ライフサイエンスニュースレター　日本語版, No. 4, pp. 31-33, 2006.

特許など

• 半田宏, 坂本聡. 蛍光性ポリマー微粒子及び蛍光標識セット. 特許. 公開. 国立大学法人東京工業大学, 多摩川精機株式会社. 2014/02/20. 特願2014-030228. 2015/08/27. 特開2015-155813. 2015. Aug.
• 勝亦 優, 半田宏, 坂本聡. 粒子の単分散状態維持方法及び分析対象物の検出方法. 特許. 公開. 国立大学法人東京工業大学, 凸版印刷株式会社. 2013/11/21. 特願2013-240897. 2015/06/04. 特開2015-102337. 2015. June
• 阿部正紀, 半田宏, 中川　貴, 多田大, 嶋津　隆一, 田中　俊行. 球状フェライトナノ粒子及びその製造方法. 特許. 登録. 国立大学法人東京工業大学. 2013/07/12. 特願2013-146286. 2014/02/13. 特開2014-028751. 特許第5733586号. 2015/04/24 2015.
• 阿部正紀, 半田宏, 中川　貴, 多田大, 嶋津　隆一, 田中　俊行. 球状フェライトナノ粒子及びその製造方法. 特許. 登録. 国立大学法人東京工業大学. 2013/07/12. 特願2013-146285. 2014/01/23. 特開2014-012632. 特許第5700590号. 2015/02/27 2015.
• 平瀬 匠, 中山 雅人, 半田 宏, 坂本 聡, 内藤 靖之. 被検物質の検出システム. 特許. 登録. 国立大学法人東京工業大学, 凸版印刷株式会社. 2013/07/02. 特願2014-523750. 2016/06/02. 再表2014/007248. 特許第6217936号. 2017/10/06 2017. Oct.
• 半田宏, 坂本聡, 河田 慎太郎. ポリマー微粒子の製造方法. 特許. 登録. 国立大学法人東京工業大学, 多摩川精機株式会社. 2013/03/29. 特願2013-071029. 2014/10/09. 特開2014-193972. 特許第6123053号. 2017/04/14 2017. Apr.
• 半田宏, 和田　忠士, 竹田　圭　. mRNAのpoly(A)鎖および/または3'末端配列の一部を切断し、翻訳反応を抑制する技術. 特許. 登録. 国立大学法人東京工業大学, 公立大学法人横浜市立大学, 株式会社陽進堂. 2012/07/17. 特願2013-525673. 2015/02/23. 特開（再表）2013/015152. 特許第5953617号. 2016/06/24 2016.
• 阿部正紀, 中川　貴, 多田大, 半田宏, 田中　俊之. 表面修飾されたフェライト微粒子の製造方法、表面修飾されたフェライト微粒子の製造装置、フェライト微粒子の製造装置. 特許. 登録. 国立大学法人東京工業大学, 多摩川精機株式会社. 2012/06/28. 特願2012-145120. 2012/11/29. 特開2012-232893. 特許第5532356号. 2014/05/09 2014.
• 今井剛, 半田宏, 山口雄輝. 骨、関節又は歯異常症の治療物質のスクリーニング方法. 特許. 公開. 国立大学法人東京工業大学. 2012/06/22. 特願2012-140671. 2013/09/26. 特開2013-188201. 2013.
• 今井剛, 半田宏, 山口雄輝. 相乗的抗糖尿病治療剤. 特許. 登録. 国立大学法人東京工業大学. 2012/05/10. 特願2012-108729. 2013/11/21. 特開2013-234159. 特許第6015903号. 2016/10/07 2016.
• 半田宏, 畠山 士, 坂本聡. 機能性物質包含微粒子を用いたバイオセンシング方法. 特許. 登録. 国立大学法人東京工業大学. 2011/11/29. 特願2011-260624. 2013/06/10. 特開2013-113735. 特許第5924571号. 2016/04/28 2016. Apr.
• 今井剛, 半田宏. 新たに同定したインスリン分泌制御因子を用いた抗糖尿病薬剤のスクリーニング法. 特許. 登録. 国立大学法人東京工業大学. 2011/09/02. 特願2012-531980. 2013/10/31. 特開（再表）2012/029958. 特許第5881065号. 2016/02/12 2016.
• 今井剛, 半田宏. 膵臓β細胞増殖因子を利用した医薬組成物. 特許. 公開. 国立大学法人東京工業大学. 2011/06/13. 特願2012-521423. 2013/08/19. 特開（再表）2011/162115. 2013.
• 平瀬 匠, 勝亦 優, 土屋 真紀子, 星野 昭裕, 入江 新司, 中山 雅人, 半田宏, 坂本聡, 河田 慎太郎, 内藤 靖之. 標識磁性粒子を用いた被検物質の検出方法、及び被検物質の検出システム. 特許. 登録. 国立大学法人東京工業大学, 凸版印刷株式会社. 2011/03/10. 特願2011-053415. 2012/10/04. 特開2012-189453. 特許第5645020号. 2014/11/14 2014. Nov.
• 半田宏, 畠山 士, 坂本聡, 岸寛. ポリマー被覆フェライト微粒子および製造方法. 特許. 登録. 国立大学法人東京工業大学. 2010/10/28. 特願2011-538254. 2013/03/14. 特開（再表）2011/052205. 特許第5688807号. 2015/02/06 2015. Feb.
• 半田宏, 安藤秀樹, 伊藤拓水, 堀田　健太郎. サリドマイド標的因子を利用したスクリーニング方法. 特許. 登録. 国立大学法人東京工業大学, 藤本製薬株式会社. 2010/10/18. 特願2011-537238. 2013/03/14. 特開（再表）2011/049043. 特許第5660578号. 2014/12/12 2014.
• 今井　剛, 半田宏, 稲富　聡, 川井　絢矢. インスリン分泌促進剤、これを主成分叉は添加した糖尿病予防・改善剤及び同食品. 特許. 公開. 国立大学法人東京工業大学, ホクト株式会社. 2010/09/30. 特願2010-220786. 2012/04/19. 特開2012-077004. 2012.
• 今井　剛, 半田宏. 骨形成促進剤. 特許. 公開. 国立大学法人東京工業大学, 株式会社アフェニックス. 2010/09/29. 特願2010-219371. 2012/04/12. 特開2012-072095. 2012.
• 半田宏, 土井　浩司, 榎本輝也, 川野　雅章. ウイルス外殻構成タンパク質被覆構造体及びその製造方法. 特許. 公開. 国立大学法人東京工業大学. 2010/08/30. 特願2011-530804. 2013/02/07. 特開（再表）2011/030682. 2013.
• 半田宏, 中西章, 川野　雅章. 生理的条件下でのウイルス粒子様構造体及びその形成方法. 特許. 登録. 国立大学法人東京工業大学. 2010/06/14. 特願2010-135520. 2010/09/24. 特開2010-207246. 特許第5621132号. 2014/10/03 2014.
• 半田宏, 安藤秀樹, 伊藤拓水, 堀田　健太郎. 中枢神経細胞の増殖及び分化に係る中核因子を含む医薬組成物. 特許. 公開. 国立大学法人東京工業大学. 2010/05/24. 特願2011-516008. 2012/11/15. 特開（再表）2010-137547. 2012.
• 半田宏, 安藤秀樹, 伊藤拓水, 堀田　健太郎. 中枢神経細胞の増殖及び分化に係る中核因子を含む医薬組成物. 特許. 登録. 国立大学法人東京工業大学. 2010/05/24. 特願2011-516008. 2012/11/15. 特開2010-137547. 特許第5645816号. 2014/11/14 2014.
• 半田宏, 畠山 士, 阿部　正紀, 今井　乾介, 上田　政和, 村松　俊英. センチネルリンパ節の造影剤ないし同定剤、温熱療法剤. 特許. 公開. 国立大学法人東京工業大学, 学校法人慶應義塾. 2009/10/08. 特願2009-234000. 2011/04/21. 特開2011-079781. 2011.
• 半田宏, 畠山 士, 坂本　聡, 望月　勇輔, 河田　慎太郎. 蛍光分子を含有するポリマー粒子およびその製造方法. 特許. 公開. 国立大学法人東京工業大学. 2009/09/10. 特願2010-528640. 2012/02/02. 特開（再表）2010/029739. 2012.
• 半田宏, 畠山　士, 坂本聡, 望月　勇輔, 河田　慎太郎. 蛍光分子を含有するポリマー粒子およびその製造方法. 特許. 登録. 国立大学法人東京工業大学. 2009/09/10. 特願2010-528640. 2012/02/02. 特開（再表）2010/029739. 特許第5574492号. 2014/07/11 2014.
• 阿部正紀, 中川　貴, 多田　大, 山本　修平, 半田宏. 磁気温熱療法用発熱体および製造方法. 特許. 公開. 国立大学法人東京工業大学. 2009/08/04. 特願2009-181597. 2011/02/17. 特開2011-032238. 2011.
• 半田宏, 阿部正紀, 畠山 士, 坂本　聡, 多田大, 岸　寛, 西尾　広介, 北　善紀. 磁性中空粒子およびその製造方法. 特許. 公開. 国立大学法人東京工業大学. 2009/03/09. 特願2009-054774. 2010/09/24. 特開2010-208875. 2010.
• 半田宏, 畠山　士, 坂本聡, 政池　由佳, 西尾　広介, 北　善紀, 阿部正紀, 岸寛. 表面被覆無機物粒子の製造方法. 特許. 登録. 国立大学法人東京工業大学. 2008/07/25. 特願2009-524516. 2010/10/07. 特開（再表）2009/014201. 特許第5569837号. 2014/07/04 2014.
• 阿部正紀, 半田宏, 中川　貴, 多田大, 嶋津　隆一, 田中　俊行. 球状フェライトナノ粒子の製造方法. 特許. 登録. 国立大学法人東京工業大学. 2007/12/28. 特願2007-340903. 2008/09/04. 特開2008-201666. 特許第5353004号. 2013/09/06 2013.
• 阿部正紀, 中川　貴, 多田大, 半田宏, 金丸 俊. 低沸点化合物内包中空微粒子. 特許. 公開. 国立大学法人東京工業大学. 2007/09/10. 特願2007-234572. 2009/04/02. 特開2009-067684. 2009.
• 阿部正紀, 中川　貴, 多田大, 半田宏, 金丸 俊. フェライト中空微粒子の製造方法. 特許. 公開. 国立大学法人東京工業大学. 2007/09/10. 特願2007-234573. 2009/04/02. 特開2009-067606. 2009.
• 阿部正紀, 中川　貴, 多田大, 半田宏, 田中　俊之. フェライト微粒子の製造方法、フェライト微粒子、及びフェライト微粒子の製造装置. 特許. 登録. 国立大学法人東京工業大学, 多摩川精機株式会社. 2007/08/30. 特願2007-224744. 2009/03/19. 特開2009-057230. 特許第5504399号. 2014/03/28 2014.
• 半田宏, 榎本　輝也, 井上　隆昌, 西尾　広介, 澤田　航, 竹山　敏久, 上田　栄一, 西脇　州. ウイルス粒子様構造体およびそれを含有する製剤. 特許. 登録. 国立大学法人東京工業大学, コニカミノルタホールディングス株式会社. 2007/03/29. 特願2008-509810. 2009/08/20. 特開（再表）2007/116808. 特許第5364876号. 2013/09/20 2013.
• 半田宏, 澤　智華, 廣田　雅隆, 山田　丈. ウイルス感染阻害薬のスクリーニング法及びビスフォスフォネートを含む感染阻害薬. 特許. 公開. 国立大学法人東京工業大学. 2006/11/17. 特願2006-311865. 2008/06/05. 特開2008-125391. 2008.
• 半田宏, 阿部正紀, 西尾　広介, 北　善紀. 蛍光機能具備磁性ポリマー粒子とその製造方法. 特許. 登録. 国立大学法人東京工業大学. 2006/11/20. 特願2006-313493. 2008/06/05. 特開2008-127454. 特許第5156944号. 2012/12/21 2012.
• 半田宏, 山本　法明. アデノ随伴ウイルスのITRをもつDNAのヒト第19番染色体への組込み部位の制御方法. 特許. 公開. 国立大学法人東京工業大学. 2006/09/27. 特願2006-263018. 2008/04/10. 特開2008-079539. 2008.
• 半田宏, 鷲田　尚洋, 小山内　敬, 木村　幸恵. 自己免疫疾患の予防及び／又は治療剤の有効成分の同定方法. 特許. 公開. 国立大学法人東京工業大学, 第一製薬株式会社. 2006/02/27. 特願2006-050851. 2007/09/13. 特開2007-228808. 2007.
• 半田宏, 小倉　裕次. TFII-Iを利用したスクリーニング方法. 特許. 公開. 国立大学法人東京工業大学. 2005/12/28. 特願2005-379612. 2007/07/12. 特開2007-175019. 2007.
• 半田宏, 岩崎　時男, 安野　寛. 蛋白質スクリーニング装置. 特許. 登録. 国立大学法人東京工業大学, 多摩川精機株式会社. 2005/11/21. 特願2005-335469. 2007/06/07. 特開2007-139635. 特許第4862121号. 2011/11/18 2011.
• 半田宏, 安野　寛. ノズルピッチ可変型多連ノズルユニット. 特許. 登録. 国立大学法人東京工業大学, 多摩川精機株式会社. 2005/11/21. 特願2005-335477. 2007/06/07. 特開2007-139636. 特許第4747230号. 2011/05/27 2011.
• 半田宏, 阿部正紀, 郷右近 展之, 西尾　広介. 有機物質とフェライト粒子とを有する複合粒子及びその製造方法. 特許. 公開. 国立大学法人東京工業大学. 2005/09/09. 特願2005-261823. 2007/03/22. 特開2007-070195. 2007.
• 半田宏, 飯泉　陽介, 笹川　千尋. 病原性大腸菌感染症の予防治療薬のスクリーニング法. 特許. 公開. 国立大学法人東京工業大学. 2005/08/26. 特願2005-246009. 2007/03/08. 特開2007-057477. 2007.
• 半田宏, 阿部正紀, 池田　森人, 西尾　広介. 表面修飾無機微粒子の製造方法および表面修飾無機微粒子. 特許. 公開. 国立大学法人東京工業大学. 2005/03/31. 特願2005-104699. 2006/10/19. 特開2006-282582. 2006.
• 半田宏, 阿部正紀, 郷右近 展之, 池田　森人, 西尾　広介. マグネタイト微粒子の製造方法. 特許. 登録. 国立大学法人東京工業大学. 2005/02/10. 特願2005-035257. 2006/08/24. 特開2006-219353. 特許第4621911号. 2010/11/12 2010.
• 阿部正紀, 半田宏, 西開　宏史. ポリマー被覆磁性ビーズおよびその製造方法. 特許. 公開. 国立大学法人東京工業大学. 2004/11/05. 特願2004-322819. 2006/05/25. 特開2006-131771. 2006.

学位論文

• Adeno-associated virus 1型(AAV1)の増殖の解析,  本文,  Doctor of Medicine,  慶応義塾大学大学院医学研究科,  1976/--/--, 

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